Abstract:
OBJECTIVE:To evaluate the degree of ischemic changes of the small intestine after arterial embolization of proximal or distal arteries with Gelfoam particles and coils in dogs. METHODS:Superselective arterial embolization in 18 dogs was performed using a coaxial catheter system. Gelfoam occlusion of the proximal level of ileal or jejunal arteries was performed in four dogs (group A). Gelfoam occlusion of the distal level was performed in four dogs (group B). Coil occlusion of the proximal level was performed in five dogs (group C). Coil occlusion of the distal level was performed in five dogs (group D). All 18 dogs were killed 1 day after the procedure. Gross and microscopic findings were evaluated. RESULTS:The embolizations were successful in all dogs. In group B, significant mucosal destruction, lymphocyte proliferation of the submucosa and mucosa, and diffuse swelling in all layers of the intestine were found in all four dogs. Three revealed diffuse ischemic changes and one showed focal ischemic changes. In groups A and C, all the layers of the intestine were intact and did not show any ischemic changes. In group D, one dog showed erosion of a small portion of mucosa and lymphocytic infiltration. The other dogs showed nonspecific findings in all layers of the intestine. CONCLUSIONS:Proximal embolization with Gelfoam and coils as well as distal embolization with coils did not cause ischemia. However, ischemic changes in the intestinal wall could be observed after distal embolization with Gelfoam.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Han YM,Lee JM,Jin KY,Lee SY,Kim CSdoi
10.1097/00004424-199910000-00004keywords:
subject
Has Abstractpub_date
1999-10-01 00:00:00pages
629-35issue
10eissn
0020-9996issn
1536-0210journal_volume
34pub_type
杂志文章abstract:RATIONALE AND OBJECTIVES:The authors investigated whether the ability of human malignant melanoma cells to increase in cell number or their ability to remain viable was compromised by high-field strength static magnetic fields. Normal human fibroblasts also were studied to determine if any magnetic field-related altera...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199210000-00014
更新日期:1992-10-01 00:00:00
abstract::A photographic unsharp masking technique for improving the latitude of chest radiographs without sacrificing image contrast or detail is described. An unsharp mask film, prepared from a scout film of the patient's chest, is placed between the film and the front (entrance) screen in the cassette. A second radiograph th...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198107000-00007
更新日期:1981-07-01 00:00:00
abstract:OBJECTIVES:To prospectively evaluate the safety and efficacy of combined unenhanced and gadoxetic acid disodium (Gd-EOB-DTPA)-enhanced magnetic resonance (MR) imaging compared with unenhanced MR imaging and triphasic contrast-enhanced spiral computed tomography (CT) for the detection and characterization of focal liver...
journal_title:Investigative radiology
pub_type: 杂志文章,多中心研究
doi:10.1097/RLI.0b013e3181caea5b
更新日期:2010-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To develop a computer-assisted analysis of complex joint motion based on standard fluoroscopic sequences. MATERIALS AND METHODS:Fluoroscopic sequences of 10 normal shoulders and 20 patients after total shoulder arthroplasty were recorded during abduction and adduction. The analysis of the shou...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200202000-00004
更新日期:2002-02-01 00:00:00
abstract::The effect of contrast media (CM) dilution on contrast enhancement was studied using CM representing four structurally different molecular types at osmolalities ranging from 135 to 1340 mosm/kg. Diatrizoate (ionic monomer), iopamidol (nonionic monomer), ioxaglate (ionic dimer), and iodecol (nonionic dimer) were each g...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198809001-00014
更新日期:1988-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To compare the visibility and localization of extratemporal cortical lesions in extratemporal epilepsy by using curved reconstruction (CR) and three-dimensional surface rendering (3D SR) of 3D-acquired MR images and to study the degree of confidence with which localizations are made, particular...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200104000-00005
更新日期:2001-04-01 00:00:00
abstract::Dense cavitary "photopenia" was observed on 21 of 200 consecutive stress perfusion scintigrams. A prominent finding in many cases, it sometimes occupied only a portion of the region overlying the ventricular cavity, was often seen in some projections and not others, and was frequently adjacent to myocardial perfusion ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198507000-00009
更新日期:1985-07-01 00:00:00
abstract:PURPOSE:The purpose of this study was to evaluate the magnetic resonance prostate imaging reporting and data system (PI-RADS) for the detection of prostate cancer by the results of magnetic resonance imaging (MRI)-guided biopsy of the prostate as a reference standard. PATIENTS AND METHODS:In 55 patients who had underg...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000030
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to assess the impact of oral water and intravenous furosemide challenges on blood oxygenation level-dependent magnetic resonance imaging measurements in the kidney and to examine the contribution of R2 (=1/T2) to changes in R2* (=1/T2*). MATERIALS AND METHODS:This Health Insurance ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3182823591
更新日期:2013-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Studies describing the effects of radiographic contrast media (RCM) in leukocyte chemotaxis have been contradictory. No studies have been performed after in-vivo exposure. The authors assess the effect of RCM on leukocytes following in-vivo exposure. METHODS:Seventeen patients were studied aft...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199401000-00012
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to assess the value of in vivo T2 measurements to noninvasively quantify myocardial fibrosis in diabetic mice at 11.75 T. Diabetic cardiomyopathy is characterized by extracellular matrix alteration and microcirculation impairment. These conditions might provide electrical heterogeneit...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e318243e062
更新日期:2012-05-01 00:00:00
abstract:PURPOSE:The relaxivities of 3 macrocyclic gadolinium-based contrast agents (GBCAs) were determined in human plasma and blood under standardized and clinically relevant laboratory conditions. METHODS:The T1 relaxivity, r1, was determined in human plasma at 1.5, 3, and 7 T, and in human blood at 3 T at 37°C in phantoms ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000577
更新日期:2019-09-01 00:00:00
abstract::Polylysine covalently linked to moieties of gadopentetate (Gd-DTPA), for use as a macromolecular blood pool marker for contrast material-enhanced magnetic resonance imaging (MRI), was characterized by means of physicochemical measurements and pharmacokinetics in rats and rabbits and compared with Gd-DTPA. Gd-DTPA-poly...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199111000-00008
更新日期:1991-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:To estimate the sensitivity to find small coronary artery calcium lesions with use of different slice widths with electron beam tomography. MATERIALS AND METHODS:Two studies were performed. Study 1 utilized double scanning of a stationary cork phantom with three different slice thickness (1.5, ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.RLI.0000055289.97726.B1
更新日期:2003-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To present the results of two studies conducted to evaluate the pharmacokinetics and safety of iomeprol in healthy volunteers and in patients with various degrees of renal impairment. METHODS:In these two open-label, single-dose, phase I studies, a 50-mL dose of iomeprol 400 was administered i...
journal_title:Investigative radiology
pub_type: 临床试验,杂志文章
doi:10.1097/00004424-200106000-00002
更新日期:2001-06-01 00:00:00
abstract::A method is presented by whichcomputed tomography scans carried out at a number of energies may be utilized to obtain cross-sectional images of density and atomic number in addition to the conventional array of linear attenuation coefficients. This type of analysis has been carried out for various substances of biolog...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197703000-00016
更新日期:1977-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Gray scale and power Doppler sonography are commonly used to evaluate cervical lymph nodes. This study was undertaken to identify which of the features used in ultrasound of cervical lymph nodes is readily applicable in routine clinical practice. METHODS:Two hundred and eight-six patients diag...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200206000-00005
更新日期:2002-06-01 00:00:00
abstract::There are a number of sonographic findings seen in fibroadenoma of the breast. In a retrospective study, we examined the biopsy results of 59 masses given the sonographic diagnosis of fibroadenoma. We also reviewed the sonograms of an additional 26 biopsy-proven fibroadenomas that were not diagnosed as such with ultra...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198601000-00006
更新日期:1986-01-01 00:00:00
abstract::Intravenous or intra-aortic injections of meglumine iothalamate in dogs indicate a slightly different tissue distribution and excretory pattern of the meglumine cation and the iothalamate anion. Differences in serum and urinary concentrations of these ions suggest some cellular penetration of the meglumine anion. In a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197507000-00004
更新日期:1975-07-01 00:00:00
abstract::The sonographic appearance of kidneys in patients presenting with acute renal failure due to hemolytic-uremic syndrome (HUS) was evaluated and compared with that in an age-matched control series. In nine patients with HUS, the renal cortex was typically hyperechogenic and the renal pyramids appeared sonolucent. The re...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198607000-00006
更新日期:1986-07-01 00:00:00
abstract::Iohexol and meglumine-sodium diatrizoate were injected intravenously into 18 pigs as either a 99:1 or 1:99 mixture. Blood samples were taken for 30 minutes and the concentration of each of the two contrast media was measured by means of a double labeling technique with 125I and 131I. Relative concentrations of iohexol...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198511000-00016
更新日期:1985-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To assess the potential of magnetic resonance imaging (MRI) for evaluating the evolution of tumor necrosis, the authors evaluated 28 VX2 carcinomas inoculated in the thigh muscles of rabbits. METHODS:MRI of VX2 carcinomas at 2.0 T was done with spin-echo technique 1 week (14 tumors) and 3 week...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199301000-00010
更新日期:1993-01-01 00:00:00
abstract:OBJECTIVE:BR55, a vascular endothelial growth factor receptor 2 (VEGFR2)-specific ultrasound molecular contrast agent (MCA), has shown promising results in multiple preclinical models regarding cancer imaging. In this first-in-human, phase 0, exploratory study, we investigated the feasibility and safety of the MCA for ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000362
更新日期:2017-07-01 00:00:00
abstract::Recent publications of the magnetic resonance safety profile of neurostimulators, cardiac pacemakers, and other implanted devices imply that these devices are no longer a contraindication for magnetic resonance imaging. It is very promising that patients who have these implanted devices may in the future no longer be ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000185898.59140.91
更新日期:2005-12-01 00:00:00
abstract::The magnitude and time course of contrast enhancement in spontaneous canine brain tumors was determined for two contrast agents: meglumine iothalamate and sodium meglumine ioxaglate. Tumor enhancement during contrast infusion and at 5, 10, 15, 30 and 45 minutes was measured using quantitative computed tomography. Bloo...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198411001-00007
更新日期:1984-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the attenuation, size, and volume of the pericardial sinuses and recesses by using electrocardiographically triggered, noncontrast-enhanced electron beam tomography (EBT) and to consider its relation with sex, age, and heart volume. METHODS:Findings in 213 consecutive patients with...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-200006000-00004
更新日期:2000-06-01 00:00:00
abstract::Four-hour delayed contrast-enhanced computed tomography (DCECT) shows promise for improved detection of focal liver lesions. No previous studies have examined the use of nonionic contrast materials for DCECT. The authors undertook a case-controlled study in monkeys to define the relative efficacies of iopamidol and di...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198910000-00010
更新日期:1989-10-01 00:00:00
abstract::Groups of 5 fasting male and female patients aged 32-83 years were each given 3 gm of the cholecystographic contrast medium iosumetic acid in micronized form (particle size less than 20 mum); Group I with 150 ml tea (standard administration); Group II with 500 ml tea; Group III with 150 ml tea plus 10 mg metocloprami...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197607000-00009
更新日期:1976-07-01 00:00:00
abstract::Even though we have made much progress over the last decade, much still needs to be done. I am personally very pleased with the excellent management and authority of my coauthor, Joe Frank, in assuming the Acting Directorship of our DRRP. You will be hearing more from him in the immediate future about this research pr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199304001-00014
更新日期:1993-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:The authors performed a retrospective study in ultrasound to investigate new aspects in the sonomorphology of lymph node metastases of the neck. In this study, it could be demonstrated the first time that the histologic characteristics of the metastases determine the sonographic appearance. In a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199609000-00001
更新日期:1996-09-01 00:00:00