Radiologic-pathologic-clinical correlation in mechanisms of disease course.

abstract：OBJECTIVE:The objective of this study was to evaluate the diagnostic performance and safety of magnetic resonance (MR) imaging-guided percutaneous mediastinal biopsy procedures using a 0.23-T open MR system with optical tracking navigation. MATERIALS AND METHODS:A retrospective analysis of 59 participants (38 males an...

journal_title：Investigative radiology

authors： Lü Y,Fritz J,Li C,Liu M,Lee P,Wu L,Carrino JA

更新日期：2013-06-01 00:00:00

abstract：:The effects of an intravenously administered nitroxyl spin label (PCA) on the magnetic resonance imaging (MRI) appearance and relaxation times of acute canine myocardial infarctions were studied. Twenty-four hours after ligation of the left anterior descending coronary artery (LAD), animals were either sacrificed imme...

journal_title：Investigative radiology

authors： McNamara MT,Wesbey GE,Brasch RC,Sievers R,Lipton MJ,Higgins CB

更新日期：1985-09-01 00:00:00

abstract：:Due to the small size of the bronchial arteries, the bronchial circulation is difficult to study and remains poorly understood. We have utilized single photon emission computed tomography (SPECT) as a noninvasive means of studying the bronchial circulation. Imaging studies were performed in sheep before and after the ...

journal_title：Investigative radiology

authors： Chiles C,Newman GE,Blinder RA

更新日期：1990-01-01 00:00:00

abstract：:A battery of tests for toxicity assessment of new contrast media is reviewed. Cell toxicity in a protozoan culture (Blepharisma americanum); lethal dose determination in mice; EEG Spectral analysis following cisternography in rabbits; ED50 and LD50 determination by intra- and pericerebral injection in rats; intraciste...

journal_title：Investigative radiology

authors： Sovak M,Siefert HM,Ranganathan R

更新日期：1980-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Echogenic antibody-conjugated anionic liposomes have been developed that allow directed tissue targeting and acoustic enhancement. These are not efficient for gene delivery. A cationic formulation that allows directed gene delivery while retaining acoustic properties may provide more efficient ...

journal_title：Investigative radiology

authors： Tiukinhoy SD,Mahowald ME,Shively VP,Nagaraj A,Kane BJ,Klegerman ME,MacDonald RC,McPherson DD,Matsumura JS

更新日期：2000-12-01 00:00:00

abstract：:Gallbladder sclerotherapy after permanent cystic duct occlusion, to prevent gallstone recurrence in nonsurgical gallstone therapy, is at least a two-stage procedure. A balloon catheter was developed to perform gallbladder sclerotherapy with only temporary occlusion of the cystic duct, and the efficacy and safety of th...

journal_title：Investigative radiology

authors： Brakel K,Laméris JS,Vergunst H,Ten Kate FJ,Nijs HG,Terpstra OT

更新日期：1991-09-01 00:00:00

abstract：:The authors evaluated double-blind comparative and open-label clinical trials in 1,186 patients who received ioversol to evaluate the safety and efficacy of ioversol, a new nonionic low-osmolality contrast medium, at iodine concentrations of 32%, 24%, and 16%. The results indicate that ioversol was well tolerated in a...

journal_title：Investigative radiology

authors： Benamor M,Aten EM,McElvany KD,Lankin DG,James MA,Buy-Gandal T,Harashe LT,Weinandt WJ

更新日期：1989-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to develop a method to delineate the lethally frozen-tissue region (temperature less than -40°C) arising from interventional cryoablation procedures using a short tau inversion-recovery ultrashort echo-time (STIR-UTE) magnetic resonance (MR) imaging sequence. This method could serve as...

journal_title：Investigative radiology

authors： Tokuda J,Wang Q,Tuncali K,Seethamraju RT,Tempany CM,Schmidt EJ

更新日期：2020-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Interstitial laser photocoagulation (ILP) causes localized tissue necrosis. This study was performed to determine 1) whether the changes seen on computed tomography (CT) correspond to the necrosis pathologically, and 2) which CT technique best shows the necrosis. METHODS:Eighteen Wistar rats h...

journal_title：Investigative radiology

authors： Amin Z,Thurrell W,Spencer GM,Harries SA,Grant WE,Bown SG,Lees WR

更新日期：1993-12-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To measure the hepatic uptake and biliary elimination kinetics of gadolinium (Gd)-EOB-DTPA in dogs. METHOD:Two groups of four beagles each were anesthetized and given an intravenous bolus of 25 mumol/kg or 250 mumol/kg of Gd-EOB-DTPA. Blood, hepatic bile, and urine were collected over 140 minu...

journal_title：Investigative radiology

authors： Benness G,Khangure M,Morris I,Warwick A,Burrows P,Vogler H,Weinmann HJ

更新日期：1996-04-01 00:00:00

abstract：:The effect of intravenous urography (IVU) on the excretion rate and precipitation of Tamm-Horsfall glycoprotein (THG) has been evaluated in 19 patients. Urine samples were collected immediately before the administration of contrast medium (U1) and then during the period of the excretion urogram (U2). The urinary THG: ...

journal_title：Investigative radiology

authors： Dawnay AB,Thornley C,Nockler I,Webb JA,Cattell WR

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To compare image quality and geometric distortion between readout-segmented diffusion-weighted imaging (rs-DWI) and selective-excitation accelerated reduced-field of view (FOV) DWI (sTX-DWI) of the prostate. MATERIALS AND METHODS:Sixty-five patients underwent 3-T MRI of the prostate including rs-DWI and sTX-...

journal_title：Investigative radiology

authors： Barth BK,Cornelius A,Nanz D,Eberli D,Donati OF

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To investigate the correlation between intravoxel incoherent motion (IVIM) model-derived parameters and histologically determined microvascularity in pancreatic ductal adenocarcinomas (PDACs) and pancreatic neuroendocrine tumors (PNETs). MATERIALS AND METHODS:From April 2013 to May 2014, 42 patients with mal...

journal_title：Investigative radiology

authors： Klau M,Mayer P,Bergmann F,Maier-Hein K,Hase J,Hackert T,Kauczor HU,Grenacher L,Stieltjes B

更新日期：2015-11-01 00:00:00

abstract：:The use of microbubble contrast agents for general tissue delineation and perfusion enjoys steady interest in ultrasound imaging. Microbubbles as contrast materials require a small dosage and show excellent detection sensitivity. Targeting ligands on the surface of microbubbles permit the selective accumulation of the...

journal_title：Investigative radiology

authors： Klibanov AL

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVES:Comparison of intravenous Fenestra VC-enhanced computed tomography (CT) with gadopentetate dimeglumine and Ferucarbotran contrast-enhanced magnetic resonance imaging (MRI) for the in vivo imaging of hepatic ischemia/reperfusion injury (IRI) in a murine model. MATERIAL AND METHODS:After induction of hepatic ...

journal_title：Investigative radiology

authors： Choukèr A,Lizak M,Schimel D,Helmberger T,Ward JM,Despres D,Kaufmann I,Bruns C,Löhe F,Ohta A,Sitkovsky MV,Klaunberg B,Thiel M

更新日期：2008-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The reflux of ethanol into the peritoneal cavity during percutaneous ethanol injection therapy (PEIT) of liver neoplasms may cause pain and other side effects. This article studies the optimal injection technique to minimize the reflux of ethanol. METHODS:A technique using normal postmortem pi...

journal_title：Investigative radiology

authors： Vehmas T

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to evaluate the extent to which various commercially available gadolinium-containing contrast-enhancing (CE) agents can interfere with the measurement of calcium levels by currently used laboratory methods, suggesting (spurious) hypocalcemia or hypercalcemia with a potential ris...

journal_title：Investigative radiology

authors： Löwe A,Balzer T,Hirt U

更新日期：2005-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the changes in the microbubble population of a currently available ultrasound contrast agent (USCA) through attenuation measurements to optimize its clinical use. MATERIALS AND METHODS:The microbubble population from a galactose-based USCA (Levovist, Schering AG, Germany) was chara...

journal_title：Investigative radiology

authors： Correas JM,Kurtisovski E,Bridal SL,Amararene A,Hélénon O,Berger G

更新日期：2002-12-01 00:00:00

abstract：:The problem of inhomogeneous mixing encountered during hepatic artery (HA) chemotherapy infusion was assessed and a practical solution examined. A glass model of the human HA distribution was used to determine mixing homogeneity of low flow (1.4 mL/minute) dye infusion into pulsatile flow (280-300 mL/minute) of a flui...

journal_title：Investigative radiology

authors： Barth KH,Lutz RJ,Kremers PW,Miller DL

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to analyze the effect of dual-energy computed tomography (DECT) scanners and fluid characteristics on iodine quantification and to calculate the measurement variability range induced by those variables. METHODS:We performed an experimental phantom study with 4 mediastinal iodine ...

journal_title：Investigative radiology

authors： Kim H,Goo JM,Kang CK,Chae KJ,Park CM

更新日期：2018-06-01 00:00:00

abstract：:A technique to measure absolute arterial blood flow in ml/min has been developed utilizing software programs with high-speed digital recording for the off-line analysis of intra-arterial injections of contrast medium. Measurements of pulsatile flow in a phantom for a physical flow model showed that calculations with t...

journal_title：Investigative radiology

authors： Forbes G,Gray JE,Felmlee JP

更新日期：1985-03-01 00:00:00

abstract：OBJECTIVES:Ferumoxytol, an intravenous iron supplement, can be used in off-label mode as a contrast agent in magnetic resonance imaging. The aim of this study was to assess whether ferumoxytol can be used as a marker of inflammation in animal models of acute and chronic inflammatory kidney diseases. MATERIAL AND METHO...

journal_title：Investigative radiology

authors： Budjan J,Neudecker S,Schock-Kusch D,Kraenzlin B,Schoenberg SO,Michaely HJ,Attenberger UI

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Gadolinium leakage in ocular structures (GLOS) was recently observed in fluid-attenuated inversion recovery (FLAIR) images obtained the day after an initial gadolinium injection in stroke patients. The specificity of GLOS to stroke and its mechanisms remain unclear. OBJECTIVE:We investigated the factors ass...

journal_title：Investigative radiology

authors： Galmiche C,Moal B,Marnat G,Sagnier S,Schweitzer C,Dousset V,Sibon I,Tourdias T

更新日期：2021-01-19 00:00:00

abstract：RATIONALE AND OBJECTIVES:Validation of new positron emission tomography (PET) tracers or magnetic (MR) imaging contrast agents is based on isolated rodent heart preparations. The use of larger animals could provide a more direct validation using the devices used for humans. METHODS:An isolated pig heart preparation ha...

journal_title：Investigative radiology

authors： Casali C,Obadia JF,Canet E,Bendjelid K,André-Fouët X,Revel D,Janier MF

更新日期：1997-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The efficacy of gadoteridol for contrast enhancement of central nervous system pathology was assessed in a multicenter clinical trial involving 411 patients suspected of having intracranial or spinal pathology. METHODS:Magnetic resonance imaging was performed before and after intravenous admin...

journal_title：Investigative radiology

authors： Runge VM,Bronen RA,Davis KR

更新日期：1992-08-01 00:00:00

abstract：:Diagnostic radiology is expanding, playing an increasingly central role in patient care, which heightens the importance of radiology teaching in undergraduate medical education. This study examined the impact of increased structure and systematic evaluation on student performance in a radiology elective. The evaluatio...

journal_title：Investigative radiology

authors： Blane CE,Calhoun JG,Maxim BR,Martel W,Davis WK

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVE:Computed tomography (CT) and magnetic resonance imaging (MRI) are introduced as an alternative to traditional autopsy. The purpose of this study was to investigate their accuracy in mass estimation of liver and spleen. METHODS:In 44 cases, the weights of spleen and liver were estimated based on MRI and CT da...

journal_title：Investigative radiology

authors： Jackowski C,Thali MJ,Buck U,Aghayev E,Sonnenschein M,Yen K,Dirnhofer R,Vock P

更新日期：2006-07-01 00:00:00

abstract：:Early detection of pancreatic ductal adenocarcinoma (PDAC) represents the most significant step toward the treatment of this aggressive lethal disease. Previously, we engineered a preclinical Thy1-targeted microbubble (MBThy1) contrast agent that specifically recognizes Thy1 antigen overexpressed in the vasculature of...

journal_title：Investigative radiology

authors： Bam R,Daryaei I,Abou-Elkacem L,Vilches-Moure JG,Meuillet EJ,Lutz A,Marinelli ER,Unger EC,Gambhir SS,Paulmurugan R

更新日期：2020-11-01 00:00:00

abstract：:The purpose of this study was to establish the proton NMR relaxation times of collapsed but otherwise normal lung tissue and to determine whether an inflammatory process within a collapsed lung can be detected by alterations in relaxation times. The lungs of three groups of rabbits were studied: group A (n = 7) had a ...

journal_title：Investigative radiology

authors： Huber DJ,Kobzik L,Melanson G,Adams DF

更新日期：1985-08-01 00:00:00

abstract：OBJECTIVE:Though functional intravascular parameters such as blood velocity and direction of blood flow are available via imaging modalities such as Doppler ultrasound and phase contrast magnetic resonance imaging, such quantitative information is not yet supported by computed tomography (CT). In this study, we examine...

journal_title：Investigative radiology

authors： Barfett JJ,Fierstra J,Mikulis DJ,Krings T

更新日期：2010-12-01 00:00:00