Can Ferumoxytol be Used as a Contrast Agent to Differentiate Between Acute and Chronic Inflammatory Kidney Disease?: Feasibility Study in a Rat Model.

abstract：RATIONALE AND OBJECTIVES:The objective is to assess the diagnostic accuracy and interobserver variability of multiphase 3D gadolinium-enhanced magnetic resonance angiography (3D-Gd-MRA) for assessment of abdominal and pelvic vascular disease. METHODS:In 41 patients from two different institutions multiphase 3D-Gd-MRA ...

journal_title：Investigative radiology

authors： Schoenberg SO,Essig M,Hallscheidt P,Sharafuddin MJ,Stolpen AH,Knopp MV,Yuh WT

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:To determine the impact of slice thickness on semiautomatic lymph node analysis. MATERIALS AND METHODS:Thoracic multislice computed tomography (MSCT) of 46 patients with NSCLC were reconstructed at 1.0-, 3.0-, and 5.0-mm slice thickness. Two radiologists independently determined long and short axis diameter...

journal_title：Investigative radiology

authors： Buerke B,Puesken M,Beyer F,Gerss J,Weckesser M,Seifarth H,Heindel W,Wessling J

更新日期：2010-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the effect of the transverse ligament on translation of the menisci. METHODS:Six cadaveric knees were examined by MR imaging inside a positioning device before and after transecting the transverse ligament. The knees were examined at various positions: extension, 30 degrees of flex...

journal_title：Investigative radiology

authors： Muhle C,Thompson WO,Sciulli R,Pedowitz R,Ahn JM,Yeh L,Clopton P,Haghighi P,Trudell DJ,Resnick D

更新日期：1999-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Two independent gold standards and diagnoses from three-dimensional computed tomography (CT) images were used to examine the possibility that craniosynostosis is a binary abnormality that potentially may be diagnosed without error. METHODS:Surgical reports, histology of excised sutures, and th...

journal_title：Investigative radiology

authors： Pilgram TK,Vannier MW,Marsh JL,Kraemer BB,Rayne SC,Gado MH,Moran CJ,McAlister WH,Shackelford GD,Hardesty RA

更新日期：1994-10-01 00:00:00

abstract：:Frequency spectral analysis of cardiac wall motion as calculated from the recorded video kymogram are demonstrated. Characteristic harmonics following the fundamental frequency of the cardiac rate have been demonstrated to have an alternating sequential energy distribution as measured from the free margin of the left ...

journal_title：Investigative radiology

authors： Silverman NR,Rosen L,Helland DR

更新日期：1975-03-01 00:00:00

abstract：OBJECTIVE:To demonstrate a method of assessing radiologic diagnostic agreement utilizing multiple blinded external readers. METHODS:Six body CT studies interpreted by one reader (primary reader) at the host institution were compiled with patient identifiers removed. Brief clinical histories that were available to the ...

journal_title：Investigative radiology

authors： Ryan AF,Semelka RC,Molina PL,Yonkers S,Vaidean G

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate if pancreatic steatosis measured by proton density fat fraction (PDFF) is associated with exocrine pancreatic function defined by fecal elastase concentrations. MATERIALS AND METHODS:A total of 1458 volunteers (777 women; age range, 21-88 years) underwent magnetic re...

journal_title：Investigative radiology

authors： Kromrey ML,Friedrich N,Hoffmann RT,Bülow R,Völzke H,Weiss FU,Lerch MM,Motosugi U,Kühn JP

更新日期：2019-07-01 00:00:00

abstract：:The issue of dechelation (transmetallation) in vivo after administration of the linear gadolinium-based contrast agents, and potential safety concerns, is considered on the basis of an extensive, focused literature review. Early indications of potential problems included the high level of excess ligand used in the for...

journal_title：Investigative radiology

authors： Runge VM

更新日期：2018-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors used gadolinium (Gd) chelate as a T1, T2, and T2* enhancing agent in reperfused myocardial infarction to compare the appearance of reperfused myocardial infarction on spin echo and gradient echo magnetic resonance (MR) sequences. METHODS:Rats (n = 28) were subjected to reperfused m...

journal_title：Investigative radiology

authors： Geschwind JF,Saeed M,Wendland MF,Higgins CB

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:We sought to develop a robotic system for computed tomography (CT)-guided biopsy to validate the feasibility, accuracy, and efficacy of the system using phantom tests. MATERIALS AND METHODS:Ten peas (mean diameter 9.9+/-0.4 mm) embedded within a gel phantom were selected for biopsy. Once the best access was de...

journal_title：Investigative radiology

authors： Kettenbach J,Kronreif G,Figl M,Fürst M,Birkfellner W,Hanel R,Ptacek W,Bergmann H

更新日期：2005-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Because of the complex relationships between the dynamic three-dimensional cardiac surface shape and its projected image, errors arise with the use of two-dimensional silhouettes to measure displacements of the heart. The character and frequency of such errors are examined. METHODS:A high-prec...

journal_title：Investigative radiology

authors： McInerney JJ,Weldner PW,Herr MD,Copenhaver GL

更新日期：1994-03-01 00:00:00

abstract：:Lymphangiograms of canine cardiac and pulmonary efferent mediastinal lymphatics were made by cannulation and injection of Ethiodol. Injections were made singly and serially. The mediastinal lymphatics and lymph nodes, which constitute the pathways of drainage of the heart and lungs, were delineated from the point of c...

journal_title：Investigative radiology

authors： Leeds SE,Uhley HN,Meister RB

更新日期：1979-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Emulsions of perfluorocarbons (PFCs) have been tested as blood substitutes. However, evidence exists that there is long-term retention of some PFCs by the organs of the reticuloendothelial system (RES). The authors investigate organ retention of the blood substitute component, perfluorotripropy...

journal_title：Investigative radiology

authors： Meyer KL,Carvlin MJ,Mukherji B,Sloviter HA,Joseph PM

更新日期：1992-08-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Measurements of segmental contraction of the left ventricle by standard magnetic resonance imaging (MRI) and two-dimensional echocardiography involve the comparison of diastolic and systolic time frames acquired from the same imaging plane in space. As the cone-shaped left ventricle shortens al...

journal_title：Investigative radiology

authors： Pattynama PM,Doornbos J,Hermans J,van der Wall EE,de Roos A

更新日期：1992-09-01 00:00:00

abstract：:A method is presented for selective catheterization and filming of the small internal spermatic and proper hepatic arteries in rabbits. The angiograms thus obtained afford clear delineation of the vessels and their branches and can enhance radiographic investigation of a variety of experimental disease models. ...

journal_title：Investigative radiology

authors： Young S,Hollenberg NK

更新日期：1977-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Ureteric jet index (UJI), a newly developed technique derived from color Doppler ultrasonography, may hold promise in evaluating renal function because of its ability to evaluate individual renal function and the use of nonionizing radiation. To assess the usefulness of UJI, the authors in this...

journal_title：Investigative radiology

authors： Chiu NT,Wu CC,Yao WJ,Tu DG,Lee BF,Tong YC,Pan CC

更新日期：1999-08-01 00:00:00

abstract：RATIONAL AND OBJECTIVES:The feasibility of tubal occlusion by selective salpingography was tested in an animal model; three novel occluding materials also were tested for this application. METHODS:Unilateral selective salpingography was performed in three groups of six rabbits; fallopian tubes were embolized with etha...

journal_title：Investigative radiology

authors： Maubon A,Rouanet JP,Laurent A,Joujoux JM,Cover S,Courtieu C,Wassef M,Godlewski G,Honiger J,Lopez FM

更新日期：1994-02-01 00:00:00

abstract：:Previous investigations in this laboratory have confirmed the observation of facial muscle twitching during intracarotid injections of nonionic contrast media (CM) in rabbits. The reaction appears to be a locally mediated effect. To further investigate this reaction, cortical electroencephalogram (EEG) and facial elec...

journal_title：Investigative radiology

authors： Whisson CC,Evill CA,Sage MR,Wilson AJ

更新日期：1990-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Because of the greatly increased cost of nonionic, low-osmolar contrast material, some practitioners reserve its use for patients at high risk for an adverse contrast reaction. The authors attempt to evaluate the proportion of low-risk outpatients--when offered a choice between the more expensi...

journal_title：Investigative radiology

authors： Hopper KD,Matthews YL

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Nephrogenic systemic fibrosis (NSF) has been related to the use of gadolinium-based contrast agents (GBCAs) in patients undergoing dialysis. The Prospective Fibrose Nephrogénique Systémique study, a French prospective study supported by the French drug regulatory agency (Agence Nationale de Sécurité du Médic...

journal_title：Investigative radiology

authors： Amet S,Launay-Vacher V,Clément O,Frances C,Tricotel A,Stengel B,Gauvrit JY,Grenier N,Reinhardt G,Janus N,Choukroun G,Laville M,Deray G

更新日期：2014-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors investigated whether the ability of human malignant melanoma cells to increase in cell number or their ability to remain viable was compromised by high-field strength static magnetic fields. Normal human fibroblasts also were studied to determine if any magnetic field-related altera...

journal_title：Investigative radiology

authors： Short WO,Goodwill L,Taylor CW,Job C,Arthur ME,Cress AE

更新日期：1992-10-01 00:00:00

abstract：OBJECTIVE:To investigate the efficacy of true fast imaging with steady state precession (true-FISP) compared with T2-weighted fast spin echo (T2W-FSE) in monitoring changes in cyst volume and renal expansion in an ischemia reperfusion (IR) injured PKD1 knockout (IKO) mouse model. MATERIALS AND METHODS:The animal study...

journal_title：Investigative radiology

authors： Zhou X,Bao H,Takakura A,Zhou J,Albert M,Sun Y

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare the prognostic utility of a staging system using magnetic resonance imaging (MRI) with the seventh American Joint Committee on Cancer (AJCC) staging system in patients with hepatocellular carcinoma (HCC) who underwent hepatic resection. MATERIALS AND METHODS:A total of 1...

journal_title：Investigative radiology

authors： An C,Choi GH,Lee HS,Kim MJ

更新日期：2012-11-01 00:00:00

abstract：:Capacity-limited elimination of sodium iopanoate and a reproducible apparent transport maximum (Tm) were demonstrated in nonoperated dogs having an intact enterohepatic circulation and normal endogenous bile salt pool. Using a multiple infusion technique, estimation of apparent Tm of iopanoate in the liver was possibl...

journal_title：Investigative radiology

authors： Herzog RJ,Nelson JA,Staubus AE

更新日期：1976-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate a prototype dual-energy computed tomography calcium subtraction algorithm and its impact on luminal visualization in patients with heavily calcified coronary arteries. MATERIALS AND METHODS:Twenty-nine patients (62% male; mean age, 64 ± 7 years) who had undergone dual-e...

journal_title：Investigative radiology

authors： De Santis D,Jin KN,Schoepf UJ,Grant KL,De Cecco CN,Nance JW Jr,Vogl TJ,Laghi A,Albrecht MH

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:BR55, a vascular endothelial growth factor receptor 2 (VEGFR2)-specific ultrasound molecular contrast agent (MCA), has shown promising results in multiple preclinical models regarding cancer imaging. In this first-in-human, phase 0, exploratory study, we investigated the feasibility and safety of the MCA for ...

journal_title：Investigative radiology

authors： Smeenge M,Tranquart F,Mannaerts CK,de Reijke TM,van de Vijver MJ,Laguna MP,Pochon S,de la Rosette JJMCH,Wijkstra H

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:To test the technique and feasibility of translating tumor suspicious region maps in the prostate, obtained by multimodality, anatomic, and functional 3T magnetic resonance imaging (MRI) data to 32-channel coil, T2-weighted (T2-w), 3T MR images, for directing MR-guided biopsies. Furthermore, to evaluate the ...

journal_title：Investigative radiology

authors： Hambrock T,Fütterer JJ,Huisman HJ,Hulsbergen-vandeKaa C,van Basten JP,van Oort I,Witjes JA,Barentsz JO

更新日期：2008-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors conduct technical feasibility and performance studies on a new 0.009-inch nitinol microguidewire for potential neuroendovascular applications. METHODS:In vivo microcatheterizations of brachiocephalic arteries were performed in four pigs using the 0.009-inch nitinol microguidewire w...

journal_title：Investigative radiology

authors： Putman CM,Chaloupka JC,Kailasnath P,Alderman J

更新日期：1997-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this study was to determine whether cerebral fat embolism demonstrated reversible or irreversible findings in magnetic resonance (MR) imaging over time and to compare the features in MR images with histologic findings in a cat model. MATERIALS AND METHODS:MR images were obtained...

journal_title：Investigative radiology

authors： Kim HJ,Lee CH,Lee SH,Moon TY

更新日期：2003-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:It is widely believed that down-sizing catheters, and possibly needles, will decrease damage to the entry vessel in the performance of angiography. The purposes of this in vitro experiment are to determine if smaller needles produce less arterial wall damage than larger needles and to assess th...

journal_title：Investigative radiology

authors： Smith DC,Hamlin JA,Jensen DA,Pappas JM,Westengard JC,Saukel GW

更新日期：1992-10-01 00:00:00