Development of echogenic, plasmid-incorporated, tissue-targeted cationic liposomes that can be used for directed gene delivery.

abstract：:The effects of an intravenously administered nitroxyl spin label (PCA) on the magnetic resonance imaging (MRI) appearance and relaxation times of acute canine myocardial infarctions were studied. Twenty-four hours after ligation of the left anterior descending coronary artery (LAD), animals were either sacrificed imme...

journal_title：Investigative radiology

authors： McNamara MT,Wesbey GE,Brasch RC,Sievers R,Lipton MJ,Higgins CB

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to assess and compare the overall performance, reliability, variability, as well as the accuracy of diffusion tensor imaging (DTI) and fiber tracking metrics, for the muscles of the calf at 3 T and 7 T. MATERIALS AND METHODS:Ten volunteers (5 males; mean age, 29.1 ± 4.7 years), with...

journal_title：Investigative radiology

authors： Giraudo C,Motyka S,Weber M,Feiweier T,Trattnig S,Bogner W

更新日期：2019-01-01 00:00:00

abstract：RATIONAL AND OBJECTIVES:The feasibility of tubal occlusion by selective salpingography was tested in an animal model; three novel occluding materials also were tested for this application. METHODS:Unilateral selective salpingography was performed in three groups of six rabbits; fallopian tubes were embolized with etha...

journal_title：Investigative radiology

authors： Maubon A,Rouanet JP,Laurent A,Joujoux JM,Cover S,Courtieu C,Wassef M,Godlewski G,Honiger J,Lopez FM

更新日期：1994-02-01 00:00:00

abstract：:Human gallstones were surgically placed into the gallbladders of 200 swine. Eight of these swine were used as a prospective series to verify that the placement and presence of human gallstones in their gallbladders caused no significant pathologic changes in the gallbladder and that the gallstones were not spontaneous...

journal_title：Investigative radiology

authors： Griffith SL,Burney BT,Fry FJ,Franklin TD Jr

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVES:: To evaluate the performance of a gadolinium-based contrast compound (P846) as well as an ultra-small particle of iron oxide agent (P904) in contrast-enhanced magnetic resonance angiography (MRA) in rabbits and to compare those agents with gadoterate meglumine (Gd-DOTA) for first pass and steady state imagi...

journal_title：Investigative radiology

authors： Kinner S,Maderwald S,Parohl N,Albert J,Corot C,Robert P,Barkhausen J,Vogt FM

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to analyze the effect of dual-energy computed tomography (DECT) scanners and fluid characteristics on iodine quantification and to calculate the measurement variability range induced by those variables. METHODS:We performed an experimental phantom study with 4 mediastinal iodine ...

journal_title：Investigative radiology

authors： Kim H,Goo JM,Kang CK,Chae KJ,Park CM

更新日期：2018-06-01 00:00:00

abstract：:The authors correlated sonographic findings with histologic findings in a rabbit model of osteomyelitis. Staphylococcus aureus osteomyelitis was induced in the femora of 11 New Zealand white rabbits. The opposite leg was used as a control. Sonographic findings showed fluid adjacent to the bone in 11 cases. The fluid w...

journal_title：Investigative radiology

authors： Abiri MM,DeAngelis GA,Kirpekar M,Abou AN,Ablow RC

更新日期：1992-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this study evaluating a cesium iodide-amorphous silicon-based flat-panel detector was to optimize the x-ray spectrum for chest radiography combining excellent contrast-detail visibility with reduced patient exposure. MATERIALS AND METHODS:A Lucite plate with 36 drilled holes of ...

journal_title：Investigative radiology

authors： Hamer OW,Völk M,Zorger N,Borisch I,Büttner R,Feuerbach S,Strotzer M

更新日期：2004-10-01 00:00:00

abstract：:Renal arteriography gives a reliable anatomic delineation of the renal vasculature. However, the presence of renal arterial disease does not determine the physiologic significance of the lesion. The intravenous infusion of saralasin, a specific angiotensin II antagonist, has been investigated as a method for identify...

journal_title：Investigative radiology

authors： Tegtmeyer CJ,Latour EA,Vaughan ED Jr,Ayers CR,Carey RM,Wellons HA Jr

更新日期：1977-11-01 00:00:00

abstract：:Computed tomography followed by sectional radiography and photography as performed on eight cadaveric specimens in order to define the anatomy and normal motion of both the proximal and the distal radioulnar articulations. Osseous landmarks were defined that allowed measurement of rotation at the glenohumeral, proxima...

journal_title：Investigative radiology

authors： Cone RO,Szabo R,Resnick D,Gelberman R,Taleisnik J,Gilula LA

更新日期：1983-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors studied the incidence and distribution of orthopedic injuries sustained in Operation Desert Shield and Desert Storm by evaluating whether existing diagnostic imaging modalities were sufficient to diagnose the types of musculoskeletal injuries incurred. The authors also sought to det...

journal_title：Investigative radiology

authors： Truax AL,Chandnani VP,Chacko AK,Gonzalez DM

更新日期：1997-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare the visibility and localization of extratemporal cortical lesions in extratemporal epilepsy by using curved reconstruction (CR) and three-dimensional surface rendering (3D SR) of 3D-acquired MR images and to study the degree of confidence with which localizations are made, particular...

journal_title：Investigative radiology

authors： Meiners LC,Scheffers JM,De Kort GA,Burger H,Van Huffelen AC,Van Rijen PC,Van Veelen CW

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVE:To demonstrate a method of assessing radiologic diagnostic agreement utilizing multiple blinded external readers. METHODS:Six body CT studies interpreted by one reader (primary reader) at the host institution were compiled with patient identifiers removed. Brief clinical histories that were available to the ...

journal_title：Investigative radiology

authors： Ryan AF,Semelka RC,Molina PL,Yonkers S,Vaidean G

更新日期：2010-04-01 00:00:00

abstract：:Simultaneous inflation of two balloons may be necessary for balloon dilation valvuloplasty in patients with a large annulus. We examined the cardiovascular effects of dilating the pulmonary annulus with two balloons in 18 normal dogs using pulsed Doppler ultrasound and gross and microscopic examination. When the ratio...

journal_title：Investigative radiology

authors： Butto F,Burke B,Berry JM,Amplatz K,Bass JL

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVE:Though functional intravascular parameters such as blood velocity and direction of blood flow are available via imaging modalities such as Doppler ultrasound and phase contrast magnetic resonance imaging, such quantitative information is not yet supported by computed tomography (CT). In this study, we examine...

journal_title：Investigative radiology

authors： Barfett JJ,Fierstra J,Mikulis DJ,Krings T

更新日期：2010-12-01 00:00:00

abstract：:Three facets of dual-energy quantitative computed tomography are studied: (1) the algorithm for postprocessing data (the methods of Cann, Laval-Jeantet et al, Goodsitt et al [two methods], and Nickoloff et al); (2) the influence of choice of tissue-equivalent materials for calibration; and (3) the difference between c...

journal_title：Investigative radiology

authors： van Kuijk C,Grashuis JL,Steenbeek JC,Schütte HE,Trouerbach WT

更新日期：1990-08-01 00:00:00

abstract：:We evaluated the density distribution (anterior-posterior) of the right lung in 19 acutely anesthetized supine dogs using computed transmission tomography (CTT). Eleven dogs served as controls, and eight received 0.12 cc/kg of intravenously administered oleic acid. The latter were sequentially imaged over 1 hour. Nine...

journal_title：Investigative radiology

authors： Slutsky RA,Long S,Peck WW,Higgins CB,Mattrey R

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:Gadolinium leakage in ocular structures (GLOS) was recently observed in fluid-attenuated inversion recovery (FLAIR) images obtained the day after an initial gadolinium injection in stroke patients. The specificity of GLOS to stroke and its mechanisms remain unclear. OBJECTIVE:We investigated the factors ass...

journal_title：Investigative radiology

authors： Galmiche C,Moal B,Marnat G,Sagnier S,Schweitzer C,Dousset V,Sibon I,Tourdias T

更新日期：2021-01-19 00:00:00

abstract：OBJECTIVE:To investigate the efficacy of true fast imaging with steady state precession (true-FISP) compared with T2-weighted fast spin echo (T2W-FSE) in monitoring changes in cyst volume and renal expansion in an ischemia reperfusion (IR) injured PKD1 knockout (IKO) mouse model. MATERIALS AND METHODS:The animal study...

journal_title：Investigative radiology

authors： Zhou X,Bao H,Takakura A,Zhou J,Albert M,Sun Y

更新日期：2010-01-01 00:00:00

abstract：:Even though we have made much progress over the last decade, much still needs to be done. I am personally very pleased with the excellent management and authority of my coauthor, Joe Frank, in assuming the Acting Directorship of our DRRP. You will be hearing more from him in the immediate future about this research pr...

journal_title：Investigative radiology

authors： Putman CE,Frank JA

更新日期：1993-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To develop a computer-assisted analysis of complex joint motion based on standard fluoroscopic sequences. MATERIALS AND METHODS:Fluoroscopic sequences of 10 normal shoulders and 20 patients after total shoulder arthroplasty were recorded during abduction and adduction. The analysis of the shou...

journal_title：Investigative radiology

authors： Pfirrmann CW,Huser M,Székely G,Hodler J,Gerber C

更新日期：2002-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the safety and pharmacokinetics of a newly developed MR contrast medium consisting of very small superparamagnetic iron oxide particles (VSOP) coated with citrate (VSOP-C184) in a clinical phase I trial. METHODS:A total of 18 healthy subjects received either VSOP-C184 (core diamete...

journal_title：Investigative radiology

authors： Taupitz M,Wagner S,Schnorr J,Kravec I,Pilgrimm H,Bergmann-Fritsch H,Hamm B

更新日期：2004-07-01 00:00:00

abstract：:High-resolution real-time ultrasonography (5, 7.5, and 10 MHz) was used to examine the menisci of the knee in ten normal volunteers and in ten patients with knee injuries. The posterior horns of the medial and lateral menisci were easily demonstrated. Normal anatomy and pathologic changes could be imaged in the menisc...

journal_title：Investigative radiology

authors： Selby B,Richardson ML,Montana MA,Teitz CC,Larson RV,Mack LA

更新日期：1986-04-01 00:00:00

abstract：PURPOSE:To evaluate the feasibility of ex vivo ablation implementing a cryo-based internally cooled bipolar radiofrequency (RF) applicator and to determine the influence of power and gas pressure on the size and shape of the resulting ablation zones. MATERIALS AND METHODS:Two hundred twenty-five ablations were perform...

journal_title：Investigative radiology

authors： Rempp H,Voigtländer M,Clasen S,Kempf S,Neugebauer A,Schraml C,Schmidt D,Claussen CD,Enderle MD,Goldberg SN,Pereira PL

更新日期：2009-12-01 00:00:00

abstract：OBJECTIVES:Intra-arterial digital subtraction angiography (IA-DSA), an invasive procedure, is the current reference examination after percutaneous transluminal angioplasty and stenting for the detection of in-stent restenosis (ISR). In this phantom study, we evaluated flat-panel angiographic computed tomography after i...

journal_title：Investigative radiology

authors： Psychogios MN,Schramm P,Amelung N,Pilgram-Pastor SM,Gröschel K,Wasser K,Frölich AM,Mohr A,Knauth M

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To determine the prevalence of nephrogenic systemic fibrosis (NSF) in patients with chronic kidney disease (CKD) who have received gadopentetate dimeglumine. MATERIALS AND METHODS:We retrospectively studied all patients who underwent contrast-enhanced magnetic resonance imagings (CE-MRIs) between January 1, ...

journal_title：Investigative radiology

authors： Hope TA,Herfkens RJ,Denianke KS,LeBoit PE,Hung YY,Weil E

更新日期：2009-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors developed a two-dimensional breathhold magnetic resonance (MR) technique for the direct imaging of pulmonary emboli. METHODS:In vitro MR imaging was performed to demonstrate the potential generation of clot-blood contrast by in vivo pulmonary embolism (PE). A two-dimensional magnet...

journal_title：Investigative radiology

authors： Moody AR,Liddicoat A,Krarup K

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVE:As an imaging modality for follow-up during continuous or repeated hepatic arterial infusion chemotherapy using a hepatic intra-arterial indwelling catheter, the usefulness of CT while infusing contrast through the indwelling catheter (reservoir port) was examined. METHODS:Using reservoir ports implanted in ...

journal_title：Investigative radiology

authors： Morimoto M,Satake M,Sekiguchi R,Haruno M,Moriyama N

更新日期：1999-12-01 00:00:00

abstract：OBJECTIVE:Dynamic ventilation (3)He-MRI is a new method to assess pulmonary gas inflow. As differing airway diameters throughout the ventilatory cycle can influence gas inflow this study intends to investigate the influence of volume and timing of a He gas bolus with respect to the beginning of the tidal volume on insp...

journal_title：Investigative radiology

authors： Gast KK,Hawig K,Windirsch M,Markstaller K,Schreiber WG,Schmiedeskamp J,Düber C,Kauczor HU,Heussel CP

更新日期：2008-06-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors used gadolinium (Gd) chelate as a T1, T2, and T2* enhancing agent in reperfused myocardial infarction to compare the appearance of reperfused myocardial infarction on spin echo and gradient echo magnetic resonance (MR) sequences. METHODS:Rats (n = 28) were subjected to reperfused m...

journal_title：Investigative radiology

authors： Geschwind JF,Saeed M,Wendland MF,Higgins CB

更新日期：1998-07-01 00:00:00