Abstract:
OBJECTIVE:The aim of this study was to assess and compare the overall performance, reliability, variability, as well as the accuracy of diffusion tensor imaging (DTI) and fiber tracking metrics, for the muscles of the calf at 3 T and 7 T. MATERIALS AND METHODS:Ten volunteers (5 males; mean age, 29.1 ± 4.7 years), with no history of muscle disease, were examined twice at 3 T and 7 T, using a stimulated-echo acquisition mode DTI sequence. Signal-to-noise ratio (SNR) and DTI metrics (track numbers [trn], length [trl], volume [trv], fractional anisotropy [FA], mean [MD], axial [AD], and radial diffusivity [RD]) of the whole-calf muscles, the tibialis anterior, the gastrocnemius medialis, the gastrocnemius lateralis, and the soleus were collected. The Student t test was used to compare SNR and DTI metrics obtained at 3 T and 7 T. The coefficients of variation and the intraclass correlation coefficients were derived to assess the variability and the reliability of the DTI measurements at 3 T and 7 T. To further assess the accuracy of the measurements, the absolute difference was computed for each DTI metric at 3 T and 7 T and then compared (Student t test). The applied level of significance for all the statistical analyses was P < 0.05. RESULTS:As expected, the SNR was higher at 7 T than at 3 T (+111%; P < 0.001). At 7 T, the tracked fibers of the whole calf muscles, the gastrocnemii, and the soleus were more numerous (trn +5.5%, +3.1%, +8.5%, and +15.1%, respectively), longer (trl +13.1%, +18.8%, +19.3%, and +33.3%, respectively), and showed a greater volume (trv +12.1%, +12.2%, +14.7%, and +15.7%, respectively) than at 3 T (P < 0.05 each). The soleus demonstrated higher FA (+14.3%), lower MD (-1.7%), AD (-1.9%), and RD (-2%) at 7 T than at 3 T (P < 0.05 each), whereas the other muscles showed more heterogeneous results. The coefficients of variation were good (ie, <10%) for all DTI metrics at both 3 T and 7 T. The intraclass correlation coefficient was excellent (>0.750) at 7 T and 3 T for several DTI metrics, such as the trn of the gastrocnemii and the soleus, the trv of the gastrocnemii, the FA of the whole-calf muscles, gastrocnemius medialis, tibialis anterior, and soleus, and the RD of all investigated muscles (ie, whole-calf muscles, gastrocnemii, tibialis anterior, and soleus). There were no significant differences between the 2 consecutive measurements with each device, except for the trn of the whole-calf muscles and the FA of the gastrocnemius lateralis (higher mean absolute difference at 3 T and 7 T, respectively; P < 0.05 each). CONCLUSIONS:Despite the numerous challenges associated with DTI of the muscles, both 3 T and 7 T demonstrated reliable and precise results.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Giraudo C,Motyka S,Weber M,Feiweier T,Trattnig S,Bogner Wdoi
10.1097/RLI.0000000000000508subject
Has Abstractpub_date
2019-01-01 00:00:00pages
48-54issue
1eissn
0020-9996issn
1536-0210journal_volume
54pub_type
杂志文章abstract:OBJECTIVE:To assess prospectively, in healthy subjects and in patients with dilated cardiomyopathy (DCM) and hypertrophic obstructive cardiomyopathy (HOCM), the 3-dimensional (3D) shape, size, and motion of the mitral annulus (MA) using computed tomography (CT). MATERIALS AND METHODS:Twenty patients with no cardiac ab...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181994a73
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVES:Multidetector-row computed tomography coronary images are usually analyzed in mid-diastole (MD). Because of slow coronary motion also in end-systole (ES), we evaluated the impact on image quality of including ES images and defined an efficient reconstruction protocol. MATERIAL AND METHODS:In 50 coronary mul...
journal_title:Investigative radiology
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abstract:RATIONALE AND OBJECTIVES:To measure the hepatic uptake and biliary elimination kinetics of gadolinium (Gd)-EOB-DTPA in dogs. METHOD:Two groups of four beagles each were anesthetized and given an intravenous bolus of 25 mumol/kg or 250 mumol/kg of Gd-EOB-DTPA. Blood, hepatic bile, and urine were collected over 140 minu...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199604000-00005
更新日期:1996-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The vascular opacification characteristics of a new nonionic, dimeric contrast agent, iodixanol, have been compared with a nonionic, monomeric agent, iohexol, using ultrafast computed tomography (UFCT). METHODS:In 10 experiments with mongrel dogs, the contrast agents were alternately injected ...
journal_title:Investigative radiology
pub_type: 杂志文章
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abstract::The study aim was to define potential differences and advantages in magnetic resonance (MR) patterns of tumoral contrast enhancement using either a small molecular, extracellular fluid contrast enhancer [Gd-DTPA] or a macromolecular agent [albumin-(Gd-DTPA)20], designed for primary intravascular biodistribution. MR im...
journal_title:Investigative radiology
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journal_title:Investigative radiology
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abstract:OBJECTIVE:To investigate three-echo T2*-corrected Dixon magnetic resonance imaging (MRI) for noninvasively estimating hepatic fat content (HFC) compared with biopsy. MATERIALS AND METHODS:One hundred patients (50 men, 50 women; mean age, 57.7±14.2 years) underwent clinically indicated liver core biopsy (102 valid tiss...
journal_title:Investigative radiology
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abstract::Three facets of dual-energy quantitative computed tomography are studied: (1) the algorithm for postprocessing data (the methods of Cann, Laval-Jeantet et al, Goodsitt et al [two methods], and Nickoloff et al); (2) the influence of choice of tissue-equivalent materials for calibration; and (3) the difference between c...
journal_title:Investigative radiology
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doi:10.1097/00004424-199008000-00003
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abstract::A photographic unsharp masking technique for improving the latitude of chest radiographs without sacrificing image contrast or detail is described. An unsharp mask film, prepared from a scout film of the patient's chest, is placed between the film and the front (entrance) screen in the cassette. A second radiograph th...
journal_title:Investigative radiology
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199507000-00004
更新日期:1995-07-01 00:00:00
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journal_title:Investigative radiology
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doi:10.1097/01.rli.0000167421.83203.4e
更新日期:2005-07-01 00:00:00
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journal_title:Investigative radiology
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doi:10.1097/RLI.0000000000000381
更新日期:2017-10-01 00:00:00
abstract::Using a 1.5 T magnetic resonance imaging (MRI) system, cine phase-contrast and magnitude images were obtained in three phantoms that simulated different anatomic configurations of aortic dissection. The dissection phantoms were made of compliant materials, and pulsatile flow was used in all experiments. Phantoms diffe...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199112000-00007
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journal_title:Investigative radiology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/RLI.0000000000000121
更新日期:2015-03-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2018-10-01 00:00:00
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journal_title:Investigative radiology
pub_type: 杂志文章
doi:
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journal_title:Investigative radiology
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journal_title:Investigative radiology
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更新日期:2000-07-01 00:00:00
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journal_title:Investigative radiology
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更新日期:2014-05-01 00:00:00
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更新日期:1993-01-01 00:00:00
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journal_title:Investigative radiology
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doi:10.1097/00004424-199704000-00008
更新日期:1997-04-01 00:00:00
abstract::The large intestines of eight boxer dogs with canine histiocytic ulcerative colitis (CHUC) and 10 normal dogs were studied by in vivo angiography and postmortem microangiography. The vascular abnormalities were correlated with the gross and histologic pathology found at necropsy. The angiographic abnormalities were ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197505000-00005
更新日期:1975-05-01 00:00:00
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更新日期:2015-03-01 00:00:00