Ioversol clinical safety summary.

Abstract:

:The authors evaluated double-blind comparative and open-label clinical trials in 1,186 patients who received ioversol to evaluate the safety and efficacy of ioversol, a new nonionic low-osmolality contrast medium, at iodine concentrations of 32%, 24%, and 16%. The results indicate that ioversol was well tolerated in all patients and showed fewer adverse effects than conventional ionic agents. The diagnostic efficacy of ioversol was comparable to both conventional and other nonionic agents with respect to diagnostic quality. However, the improved patient tolerance may contribute to higher quality radiographs. The effects on renal function were monitored at 24, 48, 72, and 96 hours and did not reveal any clinically or statistically significant changes.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Benamor M,Aten EM,McElvany KD,Lankin DG,James MA,Buy-Gandal T,Harashe LT,Weinandt WJ

doi

10.1097/00004424-198906001-00020

subject

Has Abstract

pub_date

1989-06-01 00:00:00

pages

S67-72

eissn

0020-9996

issn

1536-0210

journal_volume

24 Suppl 1

pub_type

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