Abstract:
OBJECTIVE:We aimed to assess whether migraine is associated with changes in the distribution of the venous drainage through primary and secondary pathways by using phase-contrast magnetic resonance imaging (MRI). METHODS:We examined 26 patients (37.3 ± 13.9 years) with recurring migraine headaches and 26 age- and gender-matched controls with no neurologic disease (37.3 ± 13.7 years) on a 3 Tesla MR scanner. A 2D time-of-flight MR-venography of the upper neck region was performed to visualize the venous vasculature. Cine-phase contrast scans with high-velocity encoding were employed to quantify arterial inflow and flow in the primary venous channels (right and left jugular veins), whereas scans with low-velocity encoding were employed to quantify flow in the secondary venous channels (epidural, vertebral, and deep cervical veins). RESULTS:Patients with migraine showed (i) a higher prevalence of dense secondary extracranial venous networks (15 vs. 2, P = 0.00002) and (ii) a significantly larger percentage of venous outflow through secondary channels (10.5% vs. 5.5%; of total cerebral blood flow, P = 0.02). This mainly included drainage through epidural, vertebral, and deep cervical veins. CONCLUSION:Migraine patients showed a significantly larger percentage of venous outflow through secondary channels. The mechanism of this alteration remains to be elucidated. Potential mechanisms include repeated release of vasoactive substances or growth factors.
journal_name
Invest Radioljournal_title
Investigative radiologyauthors
Koerte IK,Schankin CJ,Immler S,Lee S,Laubender RP,Grosse C,Eftimov L,Milde-Busch A,Reiser M,Straube A,Heinen F,Alperin N,Ertl-Wagner Bdoi
10.1097/RLI.0b013e318210ecf5subject
Has Abstractpub_date
2011-07-01 00:00:00pages
434-40issue
7eissn
0020-9996issn
1536-0210journal_volume
46pub_type
杂志文章abstract:RATIONALE AND OBJECTIVES:Measurements of segmental contraction of the left ventricle by standard magnetic resonance imaging (MRI) and two-dimensional echocardiography involve the comparison of diastolic and systolic time frames acquired from the same imaging plane in space. As the cone-shaped left ventricle shortens al...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199209000-00004
更新日期:1992-09-01 00:00:00
abstract:OBJECTIVES:The aims of this study were to implement and systematically evaluate the performance of a new parameter-free segmented algorithm for analysis of diffusion imaging data using a combined intravoxel incoherent motion and diffusion kurtosis imaging (IVIM-DKI) model of spin diffusion in comparison with the simple...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000223
更新日期:2016-03-01 00:00:00
abstract::The developing trend for all medical images to be in digital form raises an important question: should diagnostic interpretations be made directly from a CRT or from some form of hard copy recording of the CRT? This question was studied by having two observers read a series of digital images of the thyroid including b...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198305000-00015
更新日期:1983-05-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to determine if voxel-based histogram analysis of intravoxel incoherent motion imaging (IVIM) parameters can differentiate various subtypes of renal tumors, including benign and malignant lesions. SUBJECTS AND METHODS:A total of 44 patients with renal tumors who underwent surgery a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000111
更新日期:2015-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The purpose of this study evaluating a cesium iodide-amorphous silicon-based flat-panel detector was to optimize the x-ray spectrum for chest radiography combining excellent contrast-detail visibility with reduced patient exposure. MATERIALS AND METHODS:A Lucite plate with 36 drilled holes of ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000138091.96320.f8
更新日期:2004-10-01 00:00:00
abstract::The use of microbubble contrast agents for general tissue delineation and perfusion enjoys steady interest in ultrasound imaging. Microbubbles as contrast materials require a small dosage and show excellent detection sensitivity. Targeting ligands on the surface of microbubbles permit the selective accumulation of the...
journal_title:Investigative radiology
pub_type: 杂志文章,评审
doi:10.1097/01.rli.0000199292.88189.0f
更新日期:2006-03-01 00:00:00
abstract::Renal arteriography gives a reliable anatomic delineation of the renal vasculature. However, the presence of renal arterial disease does not determine the physiologic significance of the lesion. The intravenous infusion of saralasin, a specific angiotensin II antagonist, has been investigated as a method for identify...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-197711000-00006
更新日期:1977-11-01 00:00:00
abstract:OBJECTIVES:The objectives of this study were to assess the feasibility of magnetic resonance cholangiography (MRC) using biliary-secreted gadoxetic acid at 7 T and to compare it with T2-weighted (w) MRC at 3 T. MATERIALS AND METHODS:Ten healthy volunteers were examined on a 7-T whole-body magnetic resonance system. T2...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000004
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to assess quantitative ultra-high b-value (UHB) diffusion magnetic resonance imaging (MRI)-derived parameters in comparison to standard clinical apparent diffusion coefficient (SD-ADC-2b-1000, SD-ADC-2b-1500) for the prediction of clinically significant prostate cancer, defined as G...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000712
更新日期:2021-02-01 00:00:00
abstract::Due to the small size of the bronchial arteries, the bronchial circulation is difficult to study and remains poorly understood. We have utilized single photon emission computed tomography (SPECT) as a noninvasive means of studying the bronchial circulation. Imaging studies were performed in sheep before and after the ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199001000-00014
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:Detection of pulmonary metastases is still a challenging task for magnetic resonance imaging (MRI). It was the aim of this study to evaluate the potential of a free-breathing move-during-scan turbo inversion recovery magnitude sequence for the detection of pulmonary nodules. MATERIALS AND METHODS:The sensitivi...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31816901fa
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVES:Imaging of the kidney using blood oxygen level dependent MR presents a major opportunity to examine differences in tissue oxygenation within the cortex and medulla applicable to human disease. We sought to define the differences between regions within kidneys and to optimize selection of regions of interest ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e3181b4c1e8
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:To investigate the correlation between intravoxel incoherent motion (IVIM) model-derived parameters and histologically determined microvascularity in pancreatic ductal adenocarcinomas (PDACs) and pancreatic neuroendocrine tumors (PNETs). MATERIALS AND METHODS:From April 2013 to May 2014, 42 patients with mal...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000187
更新日期:2015-11-01 00:00:00
abstract::The residency program at the University of Pennsylvania offers a 1-month fellowship for senior residents in medical student education. Instructional philosophy, methods, and content are discussed, observed, practiced, and evaluated. Close supervision and immediate feedback provide training particularly needed by futur...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199006000-00028
更新日期:1990-06-01 00:00:00
abstract::Computed tomography followed by sectional radiography and photography as performed on eight cadaveric specimens in order to define the anatomy and normal motion of both the proximal and the distal radioulnar articulations. Osseous landmarks were defined that allowed measurement of rotation at the glenohumeral, proxima...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198311000-00012
更新日期:1983-11-01 00:00:00
abstract::Maximum likelihood estimation, assuming a binormal model, has been used extensively to estimate the area under receiver operating characteristic (ROC) curves and thus provide an index of diagnostic accuracy for the comparison of two imaging systems. However, in some instances, a degenerate data set results in a fitted...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199007000-00016
更新日期:1990-07-01 00:00:00
abstract::We examined the acute systemic and renal hemodynamic effects of intravenous meglumine/sodium diatrizoate-76% and iopamidol in euvolemic and dehydrated dogs. The physiologic responses were compared with acute changes in the level of an endogenous heparin-like material (EHM). One of eight dehydrated dogs receiving diatr...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198610000-00005
更新日期:1986-10-01 00:00:00
abstract::The ideal contrast agent in patients suspected of having gastrointestinal perforation is an iso-osmolar, or nearly iso-osmolar substance, that causes no peritoneal reaction. Iopamidol is a nonionic water-soluble contrast medium that may be considered in such situations. Intraperitoneal injections of ionic and nonionic...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199002000-00008
更新日期:1990-02-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:The authors performed a retrospective study in ultrasound to investigate new aspects in the sonomorphology of lymph node metastases of the neck. In this study, it could be demonstrated the first time that the histologic characteristics of the metastases determine the sonographic appearance. In a...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199609000-00001
更新日期:1996-09-01 00:00:00
abstract:OBJECTIVES AND RATIONALE:Negative enhancement of implanted liver tumors has been achieved in preclinical studies on manganese dipyridoxal-diphosphate (Mn-DPDP), a new hepatobiliary specific contrast agent for magnetic resonance imaging (MRI). The authors investigated the effects of Mn-DPDP on primary liver cancer and i...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199306000-00011
更新日期:1993-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the efficacy of oral administration of cilostazol, an antithrombotic agent, for the prevention of thrombotic occlusion and intimal hyperplasia after stenting. METHODS:Single-bodied Z-stents were placed in the iliac arteries of 23 dogs. Before stenting, an embolizing coil was introd...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199509000-00004
更新日期:1995-09-01 00:00:00
abstract::A 144cerium-induced osteosarcoma was transplanted to athymic nude rats (Han:rnu/rnu). Nineteen of the tumor-bearing animals were used to demonstrate the characteristics of the osteosarcoma on magnetic resonance imaging (MRI) in comparison with a group of nine animals that had not received any tumor transplant. The tum...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:
更新日期:1992-03-01 00:00:00
abstract::Experimental pulmonary arteritis was produced in rabbits by intravenous injection of alveolar macrophages from donor rabbits. These animals, along with matched controls, were studied with pulmonary angiography to test the hypothesis that angiography could detect the vasculitic process in life. The animals were then sa...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198007000-00005
更新日期:1980-07-01 00:00:00
abstract:OBJECTIVE:Hydration is widely accepted as an effective measure to prevent contrast media (CM)-induced acute kidney injury (AKI). Whether bicarbonate (NaHCO₃) infusion has a greater effect than saline is disputed. Effective prevention of CM-induced AKI by NaHCO₃ has been found by several clinical trials. However, others...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0b013e31822311a9
更新日期:2011-11-01 00:00:00
abstract::Various water soluble contrast media (WSCM) were injected subcutaneously into 970 hind feet of 485 rats. Gross morphologic changes were seen after the injection and analyzed as a function of various physicochemical characteristics of WSCM. The WSCM of larger volume, higher osmolality, higher iodine content, and meglum...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199006000-00011
更新日期:1990-06-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Optimal dose schedules and total dose of ionizing radiation for human central nervous system malignancy are not known. An animal model has been developed for the investigation of rat central nervous system response to proton irradiation using magnetic resonance imaging (MRI). A clinical MRI dev...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-199504000-00003
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the impact on metal artifacts and dose efficiency of using a tin filter in combination with high-energy threshold (TH) images of a photon-counting detector (PCD) computed tomography (CT) system. MATERIALS AND METHODS:A 3D-printed spine with pedicle screws was scanned...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/RLI.0000000000000535
更新日期:2019-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To test noninvasive inductive heating of implanted vascular stents as an alternative approach for reduction or prevention of neointimal hyperplasia. METHODS:Calorimetric pretests were performed to get an orientation on the different parameters of influence for inductive heating of stents. The ...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000117881.42422.72
更新日期:2004-05-01 00:00:00
abstract:PURPOSE:We sought to develop a robotic system for computed tomography (CT)-guided biopsy to validate the feasibility, accuracy, and efficacy of the system using phantom tests. MATERIALS AND METHODS:Ten peas (mean diameter 9.9+/-0.4 mm) embedded within a gel phantom were selected for biopsy. Once the best access was de...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/01.rli.0000155285.05672.cf
更新日期:2005-04-01 00:00:00
abstract::The design and implementation of a digital radiology image management system requires the definition, evaluation, and comparison of appropriate measures of system performance. The mean throughput rate is an important measure of the actual performance of a finished system. The mean throughput rate identifies the transm...
journal_title:Investigative radiology
pub_type: 杂志文章
doi:10.1097/00004424-198602000-00014
更新日期:1986-02-01 00:00:00