Reflux of ethanol during experimental liver ethanol injections.

Abstract:

RATIONALE AND OBJECTIVES:The reflux of ethanol into the peritoneal cavity during percutaneous ethanol injection therapy (PEIT) of liver neoplasms may cause pain and other side effects. This article studies the optimal injection technique to minimize the reflux of ethanol. METHODS:A technique using normal postmortem pig livers was developed to measure the amount of reflux in different experimental injection situations. RESULTS:The proportional reflux increased significantly when the needle diameter (0.55-1.1 mm) was larger (P < .01) and when the injection was more superficial (P < .0005) (ie, the needle traversed a shorter distance [1-5 cm] inside the liver tissue). Speeding up the injection (0.13-1.5 g/second) produced suggestive (P < .10) increase of the proportional reflux. The proportional reflux was not affected by either the ethanol dose (0.40-2.06 g) or by the time lapse (0-30 seconds) after the injection when the needle was left in situ before its withdrawal. CONCLUSIONS:The reflux of ethanol during PEIT is influenced by the diameter of the needle and by the technique used. Further studies are needed to fully clarify the clinical validity of these results.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Vehmas T

doi

10.1097/00004424-199211000-00008

keywords:

subject

Has Abstract

pub_date

1992-11-01 00:00:00

pages

918-21

issue

11

eissn

0020-9996

issn

1536-0210

journal_volume

27

pub_type

杂志文章
  • Photon scattering measurement of calcaneal bone density: result of in vivo cross-sectional studies.

    abstract::The density of trabecular bone in the os calcis has been measured in 321 subjects using a gamma ray scattering technique. In normal subjects it was shown that density could be predicted from body weight and age with a standard error of 5.6%. It was also shown that the dependence of density upon weight and age was the ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198201000-00004

    authors: Roberts JG,DiTomasso E,Webber CE

    更新日期:1982-01-01 00:00:00

  • The effects of orientation on volume measurements of human left ventricular casts.

    abstract::Biplane angiocardiography has emerged as a standard method for calculating left ventricular volume measurements. Validation of such measurements has separately been made for several projections of silicone casts of the left ventricle. This study was undertaken to establish and compare the regression lines for left ven...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198011000-00002

    authors: Lipton MJ,Hayashi TT,Davis PL,Carlsson E

    更新日期:1980-11-01 00:00:00

  • Hardcopy recording technologies for digitally formatted image data.

    abstract::The hardcopy recording technologies of video cameras, slow-scan (digital spot) recorders, and laser film printers are presented and compared. Slow-scan (digital spot) recorders offer a few advantages when compared with multiformat video cameras. But only laser film printers provide the high-quality hardcopy recordings...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199102000-00017

    authors: Siegel EL,Bishop MD,Wetzel LH,Anderson WF,McMillan JH

    更新日期:1991-02-01 00:00:00

  • Photographic unsharp masking in chest radiography.

    abstract::A photographic unsharp masking technique for improving the latitude of chest radiographs without sacrificing image contrast or detail is described. An unsharp mask film, prepared from a scout film of the patient's chest, is placed between the film and the front (entrance) screen in the cassette. A second radiograph th...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198107000-00007

    authors: Sorenson JA,Niklason LT,Nelson JA

    更新日期:1981-07-01 00:00:00

  • Digital radiography versus conventional radiography for the detection of a skull fracture under varying exposure parameters.

    abstract:RATIONALE AND OBJECTIVES:The effect of varying exposure parameters on the detectability of a fracture with digital and conventional radiography were examined. METHODS:A macerated fractured skull was imaged by film-screen radiography (FSR) and digital storage phosphor radiography (DR) with various exposure values. Five...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199303000-00010

    authors: Langen HJ,Klein HM,Wein B,Schiwy-Bochat KH,Stargardt A,Günther RW

    更新日期:1993-03-01 00:00:00

  • The role of catheters and guidewires in the production of angiographic thromboembolic complications.

    abstract::Thromboembolic complications occurring during angiography may result from a number of different causes. Catheters and guidewires can interact with blood to form thrombi; this tendency is related to wall defects and the chemical composition and structural characteristics of the catheters and guidewires. Nonthrombic sou...

    journal_title:Investigative radiology

    pub_type: 杂志文章,评审

    doi:10.1097/00004424-198811002-00009

    authors: Kido DK,King PD,Manzione JV,Simon JH

    更新日期:1988-11-01 00:00:00

  • Adenosine-stress dynamic myocardial CT perfusion imaging: initial clinical experience.

    abstract:OBJECTIVE:To evaluate the feasibility of adenosine-stress dynamic myocardial volume perfusion imaging with second generation dual source computed tomography (CT) for the qualitative and quantitative assessment of myocardial blood flow (MBF) compared with stress perfusion and viability magnetic resonance imaging (MRI). ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3181dfa2f2

    authors: Bastarrika G,Ramos-Duran L,Rosenblum MA,Kang DK,Rowe GW,Schoepf UJ

    更新日期:2010-06-01 00:00:00

  • Potential of dose reduction after marker placement with full-field digital mammography.

    abstract:OBJECTIVES:The purpose of our study was to assess the potential for radiation dose reduction in digital postinterventional digital mammograms after marker placement. MATERIALS AND METHODS:One hundred consecutive cases of marker placement (hook-wire localization or postbiopsy clip marker placement), with 200 full-field...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000163743.63063.9f

    authors: Riedl CC,Jaromi S,Floery D,Pfarl G,Fuchsjaeger MH,Helbich TH

    更新日期:2005-06-01 00:00:00

  • Mitral annular shape, size, and motion in normals and in patients with cardiomyopathy: evaluation with computed tomography.

    abstract:OBJECTIVE:To assess prospectively, in healthy subjects and in patients with dilated cardiomyopathy (DCM) and hypertrophic obstructive cardiomyopathy (HOCM), the 3-dimensional (3D) shape, size, and motion of the mitral annulus (MA) using computed tomography (CT). MATERIALS AND METHODS:Twenty patients with no cardiac ab...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3181994a73

    authors: Alkadhi H,Desbiolles L,Stolzmann P,Leschka S,Scheffel H,Plass A,Schertler T,Trindade PT,Genoni M,Cattin P,Marincek B,Frauenfelder T

    更新日期:2009-04-01 00:00:00

  • A new class of contrast agents for magnetic resonance imaging based on selective reduction of water-T2 by chemical exchange.

    abstract::Compounds containing mobile protons can act as contrast agents by increasing the value of the term (1/12 - 1/11). The efficiency of this method is markedly pH- and field-dependent. There are many such compounds allowing a choice to be made based on the characteristics of the tissue or organ, magnetic field strength, a...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198809001-00058

    authors: Aime S,Nano R,Grandi M

    更新日期:1988-09-01 00:00:00

  • The importance of nuclear magnetic relaxation dispersion (NMRD) profiles in MRI contrast media development.

    abstract::Observation of the relaxivity of MRI contrast media over a wide range of magnetic fields is not only necessary for predicting their efficiency at any field but also compulsory for understanding and improving their mechanisms of action. The best experimental approach to this problem is the field cycling method, which a...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198809001-00047

    authors: Muller RN,Vander Elst L,Rinck PA,Vallet P,Maton F,Fischer H,Roch A,Van Haverbeke Y

    更新日期:1988-09-01 00:00:00

  • Attenuation correction for flexible magnetic resonance coils in combined magnetic resonance/positron emission tomography imaging.

    abstract:INTRODUCTION:Attenuation correction for magnetic resonance (MR) coils is a new challenge that came about with the development of combined MR and positron emission tomography (PET) imaging. This task is difficult because such coils are not directly visible on either PET or MR acquisitions with current combined scanners ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3182a530f8

    authors: Eldib M,Bini J,Calcagno C,Robson PM,Mani V,Fayad ZA

    更新日期:2014-02-01 00:00:00

  • Large-tip-angle spin-echo imaging. Theory and applications.

    abstract:RATIONALE AND OBJECTIVES:Tissue contrast phenomenology was investigated analytically and clinically for a class of magnetic resonance (MR) pulse sequences we call large-tip-angle (LTA) spin-echo (SE) imaging. In comparison to traditional SE sequences (denoted 90 degrees-180 degrees-echo), the LTA sequence is of the for...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199310000-00017

    authors: Elster AD,Provost TJ

    更新日期:1993-10-01 00:00:00

  • Systematic evaluation and increased structure in a radiology elective.

    abstract::Diagnostic radiology is expanding, playing an increasingly central role in patient care, which heightens the importance of radiology teaching in undergraduate medical education. This study examined the impact of increased structure and systematic evaluation on student performance in a radiology elective. The evaluatio...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198505000-00003

    authors: Blane CE,Calhoun JG,Maxim BR,Martel W,Davis WK

    更新日期:1985-05-01 00:00:00

  • Noninvasive quantification of hepatic fat content using three-echo dixon magnetic resonance imaging with correction for T2* relaxation effects.

    abstract:OBJECTIVE:To investigate three-echo T2*-corrected Dixon magnetic resonance imaging (MRI) for noninvasively estimating hepatic fat content (HFC) compared with biopsy. MATERIALS AND METHODS:One hundred patients (50 men, 50 women; mean age, 57.7±14.2 years) underwent clinically indicated liver core biopsy (102 valid tiss...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31822b124c

    authors: Kühn JP,Evert M,Friedrich N,Kannengiesser S,Mayerle J,Thiel R,Lerch MM,Dombrowski F,Mensel B,Hosten N,Puls R

    更新日期:2011-12-01 00:00:00

  • Clinical Evaluation of a Multiparametric Deep Learning Model for Glioblastoma Segmentation Using Heterogeneous Magnetic Resonance Imaging Data From Clinical Routine.

    abstract:OBJECTIVES:The aims of this study were, first, to evaluate a deep learning-based, automatic glioblastoma (GB) tumor segmentation algorithm on clinical routine data from multiple centers and compare the results to a ground truth, manual expert segmentation, and second, to evaluate the quality of the segmentation results...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000484

    authors: Perkuhn M,Stavrinou P,Thiele F,Shakirin G,Mohan M,Garmpis D,Kabbasch C,Borggrefe J

    更新日期:2018-11-01 00:00:00

  • Ultrasonic echoes registered from erythrocytes.

    abstract::Erythrocytes at various concentrations were examined with a sensitive A-mode ultrasonic scanner; simultaneous measurements were made under light microscopic control. Individual erythrocytes caused weak (about 1 dB) echoes while erythrocyte aggregates (ten to 100 cells) produced stronger echoes (up to 15 dB), grossly p...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198508000-00014

    authors: Alanen A,Kormano M

    更新日期:1985-08-01 00:00:00

  • Computed tomography of the normal radioulnar joints.

    abstract::Computed tomography followed by sectional radiography and photography as performed on eight cadaveric specimens in order to define the anatomy and normal motion of both the proximal and the distal radioulnar articulations. Osseous landmarks were defined that allowed measurement of rotation at the glenohumeral, proxima...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198311000-00012

    authors: Cone RO,Szabo R,Resnick D,Gelberman R,Taleisnik J,Gilula LA

    更新日期:1983-11-01 00:00:00

  • New contrast media designed for x-ray energy subtraction imaging in digital mammography.

    abstract:RATIONALE AND OBJECTIVES:In contrast-enhanced dual-energy subtraction imaging 2 images acquired postcontrast media administration at different energies are subtracted to highlight structures hidden in the absence of contrast media. X-ray spectra of the newly developed digital full-field mammography units (GE Senographe...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.RLI.0000077124.24140.bd

    authors: Lawaczeck R,Diekmann F,Diekmann S,Hamm B,Bick U,Press WR,Schirmer H,Schön K,Weinmann HJ

    更新日期:2003-09-01 00:00:00

  • Clinical experience with saralasin infusion in hypertensive patients.

    abstract::Renal arteriography gives a reliable anatomic delineation of the renal vasculature. However, the presence of renal arterial disease does not determine the physiologic significance of the lesion. The intravenous infusion of saralasin, a specific angiotensin II antagonist, has been investigated as a method for identify...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197711000-00006

    authors: Tegtmeyer CJ,Latour EA,Vaughan ED Jr,Ayers CR,Carey RM,Wellons HA Jr

    更新日期:1977-11-01 00:00:00

  • Radiologist's responsibility in France when using contrast media.

    abstract::French physicians must obtain their patient's consent before carrying out an action that interferes with the patient's corporal integrity. The doctor must use simple, approximate, intelligent, and honest words that help the patient to reach the indispensable decision. Proof of lack of consent lies with the patient. Th...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198809001-00006

    authors: Alméras JP,Husson R,Moreau JF

    更新日期:1988-09-01 00:00:00

  • Perfusion quantitation by ultrafast computed tomography.

    abstract::Flow measurements can be made with computed tomography (CT) scanners using iodinated, nonionic contrast media as a first-pass indicator. Ultrafast CT (UFCT) is an ideal machine to make these measurements because of its short scan time (50 mseconds) and interscan delay (< or = 0.6 seconds). Additionally, UFCT can acqui...

    journal_title:Investigative radiology

    pub_type: 杂志文章,评审

    doi:10.1097/00004424-199212002-00004

    authors: Gould RG

    更新日期:1992-12-01 00:00:00

  • Design of an isolated pig heart preparation for positron emission tomography and magnetic resonance imaging.

    abstract:RATIONALE AND OBJECTIVES:Validation of new positron emission tomography (PET) tracers or magnetic (MR) imaging contrast agents is based on isolated rodent heart preparations. The use of larger animals could provide a more direct validation using the devices used for humans. METHODS:An isolated pig heart preparation ha...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199711000-00010

    authors: Casali C,Obadia JF,Canet E,Bendjelid K,André-Fouët X,Revel D,Janier MF

    更新日期:1997-11-01 00:00:00

  • Treatment of experimental adenocarcinomas by percutaneous intratumoral injection of absolute ethanol.

    abstract::Percutaneous injection of absolute ethanol into adenocarcinomas implanted in the hind leg of rats was evaluated as a potential cancer treatment. Intramuscular alcohol injections up to 10 mL/kg produced a local dose-dependent coagulation necrosis followed by granulation tissue formation and subsequent fibrosis but no a...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198706000-00005

    authors: Burgener FA,Steinmetz SD

    更新日期:1987-06-01 00:00:00

  • Evaluation of postprocessing dual-energy methods in quantitative computed tomography. Part 2. Practical aspects.

    abstract::Three facets of dual-energy quantitative computed tomography are studied: (1) the algorithm for postprocessing data (the methods of Cann, Laval-Jeantet et al, Goodsitt et al [two methods], and Nickoloff et al); (2) the influence of choice of tissue-equivalent materials for calibration; and (3) the difference between c...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199008000-00003

    authors: van Kuijk C,Grashuis JL,Steenbeek JC,Schütte HE,Trouerbach WT

    更新日期:1990-08-01 00:00:00

  • First-in-Human Ultrasound Molecular Imaging With a VEGFR2-Specific Ultrasound Molecular Contrast Agent (BR55) in Prostate Cancer: A Safety and Feasibility Pilot Study.

    abstract:OBJECTIVE:BR55, a vascular endothelial growth factor receptor 2 (VEGFR2)-specific ultrasound molecular contrast agent (MCA), has shown promising results in multiple preclinical models regarding cancer imaging. In this first-in-human, phase 0, exploratory study, we investigated the feasibility and safety of the MCA for ...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000362

    authors: Smeenge M,Tranquart F,Mannaerts CK,de Reijke TM,van de Vijver MJ,Laguna MP,Pochon S,de la Rosette JJMCH,Wijkstra H

    更新日期:2017-07-01 00:00:00

  • Osteosarcoma of the nude rat. A model for experimental magnetic resonance imaging studies of bone tumors.

    abstract::A 144cerium-induced osteosarcoma was transplanted to athymic nude rats (Han:rnu/rnu). Nineteen of the tumor-bearing animals were used to demonstrate the characteristics of the osteosarcoma on magnetic resonance imaging (MRI) in comparison with a group of nine animals that had not received any tumor transplant. The tum...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:

    authors: Witzel JG,Bohndorf K,Prescher A,Adam G

    更新日期:1992-03-01 00:00:00

  • Contrast-enhanced magnetic resonance angiography in rabbits: evaluation of the gadolinium-based agent p846 and the iron-based blood pool agent p904 in comparison with gadoterate meglumine.

    abstract:OBJECTIVES:: To evaluate the performance of a gadolinium-based contrast compound (P846) as well as an ultra-small particle of iron oxide agent (P904) in contrast-enhanced magnetic resonance angiography (MRA) in rabbits and to compare those agents with gadoterate meglumine (Gd-DOTA) for first pass and steady state imagi...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31821ae21f

    authors: Kinner S,Maderwald S,Parohl N,Albert J,Corot C,Robert P,Barkhausen J,Vogt FM

    更新日期:2011-08-01 00:00:00

  • Intravoxel incoherent motion diffusion-weighted imaging of pancreatic neuroendocrine tumors: prediction of the histologic grade using pure diffusion coefficient and tumor size.

    abstract:PURPOSE:The purpose of this study was to assess the value of intravoxel incoherent motion and diffusion-weighted imaging for predicting the histologic grade of pancreatic neuroendocrine tumors (PNETs). MATERIALS AND METHODS:Forty patients with surgically diagnosed PNETs who underwent preoperative magnetic resonance im...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000028

    authors: Hwang EJ,Lee JM,Yoon JH,Kim JH,Han JK,Choi BI,Lee KB,Jang JY,Kim SW,Nickel MD,Kiefer B

    更新日期:2014-06-01 00:00:00

  • Development, chemistry, and physical properties of iopamidol and its analogues.

    abstract::A series of 5-hydroxyacylamino-2,4,6-triiodo-N,N'-hydroxy-alkyl-isophtalamides was prepared in order to study the structural requirements for high water solubility and low toxicity. Among the amides substituted by 2-hydroxyethyl; 2,3-dihydroxypropyl; 1,3-dihydroxypropyl-; and 1,1-dihydroxy-methyl-2-oxyethyl- groups, t...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198011001-00065

    authors: Pitrè D,Felder E

    更新日期:1980-11-01 00:00:00