The importance of nuclear magnetic relaxation dispersion (NMRD) profiles in MRI contrast media development.

abstract：OBJECTIVES:The aims of this study were to present a deep learning approach for the automated classification of multiple sclerosis and its mimics and compare model performance with that of 2 expert neuroradiologists. MATERIALS AND METHODS:A total of 268 T2-weighted and T1-weighted brain magnetic resonance imagin scans ...

journal_title：Investigative radiology

authors： Rocca MA,Anzalone N,Storelli L,Del Poggio A,Cacciaguerra L,Manfredi AA,Meani A,Filippi M

更新日期：2020-10-26 00:00:00

abstract：PURPOSE:To determine the reproducibility, accuracy, and predictors of accuracy of computed tomography (CT) angiography to detect and characterize coronary atherosclerotic plaque as compared with intravascular ultrasound. METHODS:Ten ex vivo human coronary arteries were imaged in a moving phantom by dual-source CT (col...

journal_title：Investigative radiology

authors： van der Giessen AG,Toepker MH,Donelly PM,Bamberg F,Schlett CL,Raffle C,Irlbeck T,Lee H,van Walsum T,Maurovich-Horvat P,Gijsen FJ,Wentzel JJ,Hoffmann U

更新日期：2010-11-01 00:00:00

abstract：:The ideal contrast agent in patients suspected of having gastrointestinal perforation is an iso-osmolar, or nearly iso-osmolar substance, that causes no peritoneal reaction. Iopamidol is a nonionic water-soluble contrast medium that may be considered in such situations. Intraperitoneal injections of ionic and nonionic...

journal_title：Investigative radiology

authors： Ferrante SL,Schreiman JS,Rouse JW,Rysavy JA,Cheng SC,Frick MP

更新日期：1990-02-01 00:00:00

abstract：RATIONAL AND OBJECTIVES:The feasibility of tubal occlusion by selective salpingography was tested in an animal model; three novel occluding materials also were tested for this application. METHODS:Unilateral selective salpingography was performed in three groups of six rabbits; fallopian tubes were embolized with etha...

journal_title：Investigative radiology

authors： Maubon A,Rouanet JP,Laurent A,Joujoux JM,Cover S,Courtieu C,Wassef M,Godlewski G,Honiger J,Lopez FM

更新日期：1994-02-01 00:00:00

abstract：:We investigated the feasibility of using intravascular ultrasound imaging to analyze vascular physiology in various arterial beds. Canine superficial femoral, external iliac, and common carotid arteries were harvested and suspended and perfused in a bath of oxygenated, heated, physiologic salt solution. A 6-Fr, 20-MHz...

journal_title：Investigative radiology

authors： Wilson MW,Webb RC,Marx MV,Meyer CR,Gallagher MA,Haarer SL,Buda AJ,Williams DM

更新日期：1991-03-01 00:00:00

abstract：:A new technique for the noninvasive measurement of an index of renal blood flow is described. The method utilizes ultrasound determined renal volume and radionuclide assessment of the mean transit time of a pertechnetate bolus through the kidneys. From this information a value for flow is calculated according to compa...

journal_title：Investigative radiology

authors： Powers TA,Rees RS,Bowen RD

更新日期：1983-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to optimize computed tomography (CT) surveillance of skeletal metastases in patients with breast cancer through the use of osseous subtraction maps between baseline and follow-up examinations created by a novel software algorithm. The new postprocessing algorithm segments the origina...

journal_title：Investigative radiology

authors： Horger M,Thaiss WM,Wiesinger B,Ditt H,Fritz J,Nikolaou K,Kloth C

更新日期：2017-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:It is widely believed that down-sizing catheters, and possibly needles, will decrease damage to the entry vessel in the performance of angiography. The purposes of this in vitro experiment are to determine if smaller needles produce less arterial wall damage than larger needles and to assess th...

journal_title：Investigative radiology

authors： Smith DC,Hamlin JA,Jensen DA,Pappas JM,Westengard JC,Saukel GW

更新日期：1992-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVE:The authors performed a retrospective study in ultrasound to investigate new aspects in the sonomorphology of lymph node metastases of the neck. In this study, it could be demonstrated the first time that the histologic characteristics of the metastases determine the sonographic appearance. In a...

journal_title：Investigative radiology

authors： Mäurer J,Willam C,Steinkamp HJ,Knollmann FD,Felix R

更新日期：1996-09-01 00:00:00

abstract：:The issue of dechelation (transmetallation) in vivo after administration of the linear gadolinium-based contrast agents, and potential safety concerns, is considered on the basis of an extensive, focused literature review. Early indications of potential problems included the high level of excess ligand used in the for...

journal_title：Investigative radiology

authors： Runge VM

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:Commercially available iodinated contrast media (CM) show significantly different physico-chemical properties. The relevance of the viscosity of CM may be underestimated as a contributing factor for clinically relevant renal failure as suggested by a large registry data analysis (Swedish registry study). The ...

journal_title：Investigative radiology

authors： Jost G,Pietsch H,Sommer J,Sandner P,Lengsfeld P,Seidensticker P,Lehr S,Hütter J,Sieber MA

更新日期：2009-02-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Indium-111 (111In)-labeled leukocyte scanning has been used frequently in patients suspected of having infections. Recently, technetium-99m hexamethylpropylene amine oxime (99mTc-HMPAO) has been used to label leukocytes. This study was undertaken to determine the distribution and dosimetry of 9...

journal_title：Investigative radiology

authors： Brown ML,Hung JC,Vetter RJ,O'Connor MK,Chowdhury S,Forstrom LA

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to assess the effect of age and number of previous injections of gadodiamide on the signal intensity of unenhanced T1-weighted (T1w) images of the dentate nucleus and globus pallidus in a large population. MATERIALS AND METHODS:A large, single-center retrospective population sur...

journal_title：Investigative radiology

authors： Quattrocchi CC,Errante Y,Mallio CA,Marinelli L,LoVullo G,Giannotti G,Della Sala SW,van der Molen AJ,Beomonte Zobel B

更新日期：2018-04-01 00:00:00

abstract：:Methods are presented for the quantification of spatial resolution in x-ray computed tomographic (CT) images. Model-dependent methods are derived and compared with model independent methods for computation of the Modulation Transfer Function (MTF). These techniques are applied to phantom images of point, line, edge, a...

journal_title：Investigative radiology

authors： Assimakopoulos PA,Boyd DP,Jaschke W,Lipton MJ

更新日期：1986-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The authors investigated whether the ability of human malignant melanoma cells to increase in cell number or their ability to remain viable was compromised by high-field strength static magnetic fields. Normal human fibroblasts also were studied to determine if any magnetic field-related altera...

journal_title：Investigative radiology

authors： Short WO,Goodwill L,Taylor CW,Job C,Arthur ME,Cress AE

更新日期：1992-10-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To compare electron beam tomography (EBT) with MR imaging (MRI) for detection of restenosis after coronary angioplasty (PTCA). METHODS:One hundred eighteen patients after PTCA were investigated. By EBT, 50 axial images were acquired (3-mm slice thickness, 120-160 mL radiographic contrast agent...

journal_title：Investigative radiology

authors： Ropers D,Regenfus M,Stilianakis N,Birke S,Kessler W,Moshage W,Laub G,Daniel WG,Achenbach S

更新日期：2002-07-01 00:00:00

abstract：:The use of microbubble contrast agents for general tissue delineation and perfusion enjoys steady interest in ultrasound imaging. Microbubbles as contrast materials require a small dosage and show excellent detection sensitivity. Targeting ligands on the surface of microbubbles permit the selective accumulation of the...

journal_title：Investigative radiology

authors： Klibanov AL

更新日期：2006-03-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Because of the complex relationships between the dynamic three-dimensional cardiac surface shape and its projected image, errors arise with the use of two-dimensional silhouettes to measure displacements of the heart. The character and frequency of such errors are examined. METHODS:A high-prec...

journal_title：Investigative radiology

authors： McInerney JJ,Weldner PW,Herr MD,Copenhaver GL

更新日期：1994-03-01 00:00:00

abstract：:Perfluoroctylbromide (PFOB), a radiopaque reticuloendothelial system contrast media for computed tomography, has been shown to accumulate in macrophages. In the current study PFOB was tested in rabbits as an abscess imaging agent. Two abscesses were induced in each of 24 rabbits, one in the liver and the other in the ...

journal_title：Investigative radiology

authors： Mattrey RF,Andrè M,Campbell J,Mitten R,Multer F,Hackney D,Long DM,Higgins CB

更新日期：1984-09-01 00:00:00

abstract：:Gastrografin and Amipaque with identical iodine content and flavoring were orally administered in 100 ml doses to 10 healthy volunteers in a double-blind crossover study. The nonionic Amipaque has only about one third of the osmolality of Gastrografin, and draws less fluid into the bowel lumen. Consequently there is l...

journal_title：Investigative radiology

authors： Johansen JG

更新日期：1978-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Paclitaxel added to angiographic contrast medium (CM) has been shown to inhibit restenosis in the porcine coronary overstretch model. This study determined early local tissue concentrations after the administration of different paclitaxel doses and preparations. MATERIALS AND METHODS:Fifteen p...

journal_title：Investigative radiology

authors： Speck U,Scheller B,Abramjuk C,Grossmann S,Mahnkopf D,Simon O

更新日期：2004-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine to what degree current compressed sensing methods are capable of accelerating clinical magnetic resonance neuroimaging sequences. METHODS:Two 2-dimensional clinical sequences were chosen for this study because of their long scan times. A pilot study was used to establish ...

journal_title：Investigative radiology

authors： Sharma SD,Fong CL,Tzung BS,Law M,Nayak KS

更新日期：2013-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To evaluate the short-term effects of a new nitinol stent on canine arteries. METHODS:Eighteen nitinol mesh stents were placed in abdominal aortas, common iliac arteries, and renal arteries of six dogs. Angiography was performed to evaluate the patency rates and structural changes of arteries ...

journal_title：Investigative radiology

authors： Lee KW,Park JH,Chung JW,Kim WS,Lee W,Yeon KM

更新日期：1999-05-01 00:00:00

abstract：OBJECTIVE:To investigate three-echo T2*-corrected Dixon magnetic resonance imaging (MRI) for noninvasively estimating hepatic fat content (HFC) compared with biopsy. MATERIALS AND METHODS:One hundred patients (50 men, 50 women; mean age, 57.7±14.2 years) underwent clinically indicated liver core biopsy (102 valid tiss...

journal_title：Investigative radiology

authors： Kühn JP,Evert M,Friedrich N,Kannengiesser S,Mayerle J,Thiel R,Lerch MM,Dombrowski F,Mensel B,Hosten N,Puls R

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVES:: To evaluate the performance of a gadolinium-based contrast compound (P846) as well as an ultra-small particle of iron oxide agent (P904) in contrast-enhanced magnetic resonance angiography (MRA) in rabbits and to compare those agents with gadoterate meglumine (Gd-DOTA) for first pass and steady state imagi...

journal_title：Investigative radiology

authors： Kinner S,Maderwald S,Parohl N,Albert J,Corot C,Robert P,Barkhausen J,Vogt FM

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to explore the impact of dynamic contrast-enhanced (DCE) computer tomography (CT) as a biomarker in metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS:Twelve patients with favorable or intermediate Memorial Sloan Kettering Cancer Center risk group and clear cell mRCC par...

journal_title：Investigative radiology

authors： Mains JR,Donskov F,Pedersen EM,Madsen HH,Rasmussen F

更新日期：2014-09-01 00:00:00

abstract：:The interdisciplinary approach to medical education has often been deficient in medical school curricula. Because of the nonintegrated approach to medical education, problem solving capabilities are not fostered. The clinical presentation of a patient, the imaging modalities used to investigate the patient, and the ul...

journal_title：Investigative radiology

authors： Oldham SA,Jacobson F

更新日期：1986-04-01 00:00:00

abstract：OBJECTIVE:BR55, a vascular endothelial growth factor receptor 2 (VEGFR2)-specific ultrasound molecular contrast agent (MCA), has shown promising results in multiple preclinical models regarding cancer imaging. In this first-in-human, phase 0, exploratory study, we investigated the feasibility and safety of the MCA for ...

journal_title：Investigative radiology

authors： Smeenge M,Tranquart F,Mannaerts CK,de Reijke TM,van de Vijver MJ,Laguna MP,Pochon S,de la Rosette JJMCH,Wijkstra H

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:To investigate the correlation between intravoxel incoherent motion (IVIM) model-derived parameters and histologically determined microvascularity in pancreatic ductal adenocarcinomas (PDACs) and pancreatic neuroendocrine tumors (PNETs). MATERIALS AND METHODS:From April 2013 to May 2014, 42 patients with mal...

journal_title：Investigative radiology

authors： Klau M,Mayer P,Bergmann F,Maier-Hein K,Hase J,Hackert T,Kauczor HU,Grenacher L,Stieltjes B

更新日期：2015-11-01 00:00:00

abstract：RATIONAL AND OBJECTIVES:The purpose of this study was to evaluate the effects of variation in design parameters on the resultant radial force. We evaluated the influence of wire gauge, leg length, and number of bends on the radial force produced by z stents and compared these with radial forces produced by commercial s...

journal_title：Investigative radiology

authors： Snowhill PB,Nosher JL,Siegel RL,Silver FH

更新日期：2001-09-01 00:00:00