Diminished cerebrospinal fluid beta-endorphin concentration in monkeys with arachnoiditis.

Abstract:

:Altered concentrations of brain beta endorphin and spinal cord encephalin have been reported in mice with iatrogenic arachnoiditis. We measured beta-endorphin concentration in cerebrospinal fluid (CSF) in normal monkeys and in monkeys with various degrees of arachnoiditis resulting from myelography and spinal surgery and found a significant negative correlation between the arachnoiditis score and the lumbar CSF beta-endorphin concentration. This study suggests that an assay of CSF beta endorphin can be used to detect the alterations in neurotransmitters in arachnoiditis.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Lipman BT,Haughton VM

doi

10.1097/00004424-198803000-00006

subject

Has Abstract

pub_date

1988-03-01 00:00:00

pages

190-2

issue

3

eissn

0020-9996

issn

1536-0210

journal_volume

23

pub_type

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