Effect of a new nonionic contrast agent, ioxilan, on human erythrocytes and the hemostatic and serum complement pathways.

abstract：:The magnitude and time course of contrast enhancement in spontaneous canine brain tumors was determined for two contrast agents: meglumine iothalamate and sodium meglumine ioxaglate. Tumor enhancement during contrast infusion and at 5, 10, 15, 30 and 45 minutes was measured using quantitative computed tomography. Bloo...

journal_title：Investigative radiology

authors： Fike JR,Cann CE,Norman D,Turrel JM,LeCouteur RA,Pflugfeld CM,Borcich JK

更新日期：1984-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The vascular opacification characteristics of a new nonionic, dimeric contrast agent, iodixanol, have been compared with a nonionic, monomeric agent, iohexol, using ultrafast computed tomography (UFCT). METHODS:In 10 experiments with mongrel dogs, the contrast agents were alternately injected ...

journal_title：Investigative radiology

authors： Gould R,Brasch RC,Sievers R,Baxter A,Aicher K

更新日期：1992-12-01 00:00:00

abstract：:We evaluated the density distribution (anterior-posterior) of the right lung in 19 acutely anesthetized supine dogs using computed transmission tomography (CTT). Eleven dogs served as controls, and eight received 0.12 cc/kg of intravenously administered oleic acid. The latter were sequentially imaged over 1 hour. Nine...

journal_title：Investigative radiology

authors： Slutsky RA,Long S,Peck WW,Higgins CB,Mattrey R

更新日期：1984-05-01 00:00:00

abstract：:Fractures modeled in the dried skull indicate that the initial plane of computed tomography (CT) section contributes to the accuracy of three-dimensional (3D) images generated from two-dimensional (2D) CT data. The authors retrospectively analyzed seven clinical cases of tripod zygomatic fractures that were imaged wit...

journal_title：Investigative radiology

authors： Levy RA,Kellman RM,Rosenbaum AE

更新日期：1991-05-01 00:00:00

abstract：:The authors evaluated double-blind comparative and open-label clinical trials in 1,186 patients who received ioversol to evaluate the safety and efficacy of ioversol, a new nonionic low-osmolality contrast medium, at iodine concentrations of 32%, 24%, and 16%. The results indicate that ioversol was well tolerated in a...

journal_title：Investigative radiology

authors： Benamor M,Aten EM,McElvany KD,Lankin DG,James MA,Buy-Gandal T,Harashe LT,Weinandt WJ

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVE:BR55, a vascular endothelial growth factor receptor 2 (VEGFR2)-specific ultrasound molecular contrast agent (MCA), has shown promising results in multiple preclinical models regarding cancer imaging. In this first-in-human, phase 0, exploratory study, we investigated the feasibility and safety of the MCA for ...

journal_title：Investigative radiology

authors： Smeenge M,Tranquart F,Mannaerts CK,de Reijke TM,van de Vijver MJ,Laguna MP,Pochon S,de la Rosette JJMCH,Wijkstra H

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:Contrast-enhanced ultrasound imaging is increasingly being used in the clinic for assessment of tissue vascularity. The purpose of our study was to evaluate the effect of different contrast administration parameters on the in vivo ultrasound imaging signal in tumor-bearing mice using a maximum intensity pers...

journal_title：Investigative radiology

authors： Pysz MA,Foygel K,Panje CM,Needles A,Tian L,Willmann JK

更新日期：2011-03-01 00:00:00

abstract：PURPOSE:We sought to develop a robotic system for computed tomography (CT)-guided biopsy to validate the feasibility, accuracy, and efficacy of the system using phantom tests. MATERIALS AND METHODS:Ten peas (mean diameter 9.9+/-0.4 mm) embedded within a gel phantom were selected for biopsy. Once the best access was de...

journal_title：Investigative radiology

authors： Kettenbach J,Kronreif G,Figl M,Fürst M,Birkfellner W,Hanel R,Ptacek W,Bergmann H

更新日期：2005-04-01 00:00:00

abstract：:There are a number of sonographic findings seen in fibroadenoma of the breast. In a retrospective study, we examined the biopsy results of 59 masses given the sonographic diagnosis of fibroadenoma. We also reviewed the sonograms of an additional 26 biopsy-proven fibroadenomas that were not diagnosed as such with ultra...

journal_title：Investigative radiology

authors： Jackson VP,Rothschild PA,Kreipke DL,Mail JT,Holden RW

更新日期：1986-01-01 00:00:00

abstract：UNLABELLED:Szapiro D, Ghaye B, Willems V, et al. Evaluation of CT time-density curves of lower-limb veins. Invest Radiol 2001;36:164-169. RATIONALE AND OBJECTIVES:To evaluate time-density curves of the lower-limb veins for optimization of CT venography. METHODS:Fifty patients referred for chest CT were randomized int...

journal_title：Investigative radiology

authors： Szapiro D,Ghaye B,Willems V,Zhang L,Albert A,Dondelinger RF

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVES:Transcatheter arterial embolization (TAE) is used for the treatment of patients with malignant liver tumors. However, the proangiogenesis effect of TAE-associated hypoxia has not been adequately studied. The goal of this study was to determine angiogenic activity in tumors subjected to TAE by evaluating the ...

journal_title：Investigative radiology

authors： Gupta S,Kobayashi S,Phongkitkarun S,Broemeling LD,Kan Z

更新日期：2006-06-01 00:00:00

abstract：OBJECTIVE:To investigate the efficacy of true fast imaging with steady state precession (true-FISP) compared with T2-weighted fast spin echo (T2W-FSE) in monitoring changes in cyst volume and renal expansion in an ischemia reperfusion (IR) injured PKD1 knockout (IKO) mouse model. MATERIALS AND METHODS:The animal study...

journal_title：Investigative radiology

authors： Zhou X,Bao H,Takakura A,Zhou J,Albert M,Sun Y

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:This study aims for targeted biopsy validation of magnetic resonance fingerprinting (MRF) and diffusion mapping for characterizing peripheral zone (PZ) prostate cancer and noncancers. MATERIALS AND METHODS:One hundred four PZ lesions in 85 patients who underwent magnetic resonance imaging were retrospectivel...

journal_title：Investigative radiology

authors： Panda A,OʼConnor G,Lo WC,Jiang Y,Margevicius S,Schluchter M,Ponsky LE,Gulani V

更新日期：2019-08-01 00:00:00

abstract：:The last two decades have witnessed tremendous strides in the evolution of acceptable and successful methods of prosthetic replacement for the arthritic joint. By and large, these techniques are predictable and durable, though not always to the complete satisfaction of the patient and surgeon. Despite the recent empha...

journal_title：Investigative radiology

authors： Volz RG,Benjamin JB

更新日期：1990-01-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Magnetic resonance microscopy (MRM) has evolved from a technical curiosity to a tool with which researchers can study important disease models. But MRM is not simply an extension of clinical magnetic resonance imaging. In this article, the unique adaptations of MRM required in the study of caro...

journal_title：Investigative radiology

authors： Arnder L,Zhou X,Cofer GP,Hedlund LW,Johnson GA

更新日期：1994-09-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To develop a new automated calibration method for vessel measurements in vascular x-ray images. METHODS:Radiopaque marker bands mounted equidistantly on a small catheter were acquired in vitro at five image intensifier (II) sizes in x-ray projection images. The positions of the marker centers ...

journal_title：Investigative radiology

authors： Van Assen HC,Vrooman HA,Egmont-Petersen M,Bosch HG,Koning G,Van Der Linden EL,Goedhart B,Reiber JH

更新日期：2000-04-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:To develop a computer-assisted analysis of complex joint motion based on standard fluoroscopic sequences. MATERIALS AND METHODS:Fluoroscopic sequences of 10 normal shoulders and 20 patients after total shoulder arthroplasty were recorded during abduction and adduction. The analysis of the shou...

journal_title：Investigative radiology

authors： Pfirrmann CW,Huser M,Székely G,Hodler J,Gerber C

更新日期：2002-02-01 00:00:00

abstract：:A series of 5-hydroxyacylamino-2,4,6-triiodo-N,N'-hydroxy-alkyl-isophtalamides was prepared in order to study the structural requirements for high water solubility and low toxicity. Among the amides substituted by 2-hydroxyethyl; 2,3-dihydroxypropyl; 1,3-dihydroxypropyl-; and 1,1-dihydroxy-methyl-2-oxyethyl- groups, t...

journal_title：Investigative radiology

authors： Pitrè D,Felder E

更新日期：1980-11-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to perform phantom measurements to prove the feasibility of single-source dual-energy computed tomography (DECT) of the extremities using a volume scan mode. In addition, we, for the first time, wanted to determine which concentrations of monosodium urate (MSU) in gout and calcium p...

journal_title：Investigative radiology

authors： Diekhoff T,Kiefer T,Stroux A,Pilhofer I,Juran R,Mews J,Blobel J,Tsuyuki M,Ackermann B,Hamm B,Hermann KG

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:The aims of this study were, first, to evaluate a deep learning-based, automatic glioblastoma (GB) tumor segmentation algorithm on clinical routine data from multiple centers and compare the results to a ground truth, manual expert segmentation, and second, to evaluate the quality of the segmentation results...

journal_title：Investigative radiology

authors： Perkuhn M,Stavrinou P,Thiele F,Shakirin G,Mohan M,Garmpis D,Kabbasch C,Borggrefe J

更新日期：2018-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Gd-DTPA is a well-characterized, safe contrast agent frequently used in magnetic resonance imaging (MRI) of the central nervous system. The purpose of this double-blind, comparative MRI study of brain, spine, trunk, and limbs was to evaluate the safety and efficacy of Gd-DOTA versus Gd-DTPA in ...

journal_title：Investigative radiology

authors： Oudkerk M,Sijens PE,Van Beek EJ,Kuijpers TJ

更新日期：1995-02-01 00:00:00

abstract：:In this article, we propose a semiautomatic method for time-continuous contour detection in all phases of the cardiac cycle in magnetic resonance sequences. The method is based on multidimensional dynamic programming. After shape parameterization, cost hypercubes are filled with image-feature derived cost function val...

journal_title：Investigative radiology

authors： Uzümcü M,van der Geest RJ,Swingen C,Reiber JH,Lelieveldt BP

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:The aims of this study were to compare 3 contrast agents and to define feasible doses for quantitative lung perfusion imaging using the dual-bolus approach in dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI). MATERIALS AND METHODS:Ten healthy volunteers (6 males, 4 females; mean age, 23.5 yea...

journal_title：Investigative radiology

authors： Veldhoen S,Oechsner M,Fischer A,Weng AM,Kunz AS,Bley TA,Köstler H,Ritter CO

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate the diagnostic performance and safety of magnetic resonance (MR) imaging-guided percutaneous mediastinal biopsy procedures using a 0.23-T open MR system with optical tracking navigation. MATERIALS AND METHODS:A retrospective analysis of 59 participants (38 males an...

journal_title：Investigative radiology

authors： Lü Y,Fritz J,Li C,Liu M,Lee P,Wu L,Carrino JA

更新日期：2013-06-01 00:00:00

abstract：:Perfluoroctylbromide (PFOB), a radiopaque reticuloendothelial system contrast media for computed tomography, has been shown to accumulate in macrophages. In the current study PFOB was tested in rabbits as an abscess imaging agent. Two abscesses were induced in each of 24 rabbits, one in the liver and the other in the ...

journal_title：Investigative radiology

authors： Mattrey RF,Andrè M,Campbell J,Mitten R,Multer F,Hackney D,Long DM,Higgins CB

更新日期：1984-09-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to assess the value of in vivo T2 measurements to noninvasively quantify myocardial fibrosis in diabetic mice at 11.75 T. Diabetic cardiomyopathy is characterized by extracellular matrix alteration and microcirculation impairment. These conditions might provide electrical heterogeneit...

journal_title：Investigative radiology

authors： Bun SS,Kober F,Jacquier A,Espinosa L,Kalifa J,Bonzi MF,Kopp F,Lalevee N,Zaffran S,Deharo JC,Cozzone PJ,Bernard M

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:Magnetic resonance-guided high-intensity focused ultrasound (MR-HIFU) is a method to heat lesions noninvasively to a stable, elevated temperature and a well-suited method to induce local hyperthermia (41°C-43°C) in deep-seated tissues. Magnetic Resonance (MR) imaging provides therapy planning on anatomical i...

journal_title：Investigative radiology

authors： Kneepkens E,Heijman E,Keupp J,Weiss S,Nicolay K,Grüll H

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:Hydration is widely accepted as an effective measure to prevent contrast media (CM)-induced acute kidney injury (AKI). Whether bicarbonate (NaHCO₃) infusion has a greater effect than saline is disputed. Effective prevention of CM-induced AKI by NaHCO₃ has been found by several clinical trials. However, others...

journal_title：Investigative radiology

authors： Ladwig M,Flemming B,Seeliger E,Sargsyan L,Persson PB

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of a dual magnetic resonance-near infrared fluorescence optical imaging agent, poly(l-glutamic acid)-DTPA-Gd-NIR813, for both preoperative and intraoperative visualization and characterization of sentinel lymph nodes (SLN) in mice. MATERIALS AND METHODS:Poly(L-glutamic acid) was...

journal_title：Investigative radiology

authors： Melancon MP,Wang Y,Wen X,Bankson JA,Stephens LC,Jasser S,Gelovani JG,Myers JN,Li C

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVES:Dynamic contrast-enhanced imaging allows assessing functional information in addition to morphology using various modalities. Several applications have been established in clinical practice; however, there is no standard with respect to injection protocols or postprocessing algorithms. The purpose of this st...

journal_title：Investigative radiology

authors： Brauweiler R,Eisa F,Hupfer M,Nowak T,Kolditz D,Kalender WA

更新日期：2012-08-01 00:00:00