Minimal spinal hyperostosis with low-dose isotretinoin therapy.

Abstract:

:Skeletal abnormalities have been reported on numerous occasions in patients who have received high doses of vitamin A and its derivatives. Recently, a new derivative, isotretinoin (Accutane, Hoffman-LaRoche, Inc.), has become available for the treatment of cystic acne. Ninety-six patients treated for a minimum of four months with low doses of this drug at two University centers have shown overall good to excellent clinical responses. However, ten of these patients have developed small pointed excrescences on the anterior margins of cervical, thoracic, or lumbar vertebral bodies. The findings are of unknown clinical significance but show some similarities to the spinal findings in DISH syndrome. Follow-up studies will be obtained, but, at the present time, the drug still can be recommended for patients who have severe cystic acne because of the excellent clinical response.

journal_name

Invest Radiol

journal_title

Investigative radiology

authors

Kilcoyne RF,Cope R,Cunningham W,Nardella FA,Denman S,Franz TJ,Hanifin J

doi

10.1097/00004424-198601000-00007

subject

Has Abstract

pub_date

1986-01-01 00:00:00

pages

41-4

issue

1

eissn

0020-9996

issn

1536-0210

journal_volume

21

pub_type

杂志文章
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    abstract:RATIONALE AND OBJECTIVES:To evaluate different vein graft-coated stent systems in the endovascular treatment of experimental arteriovenous fistulae (AVF) in a canine model. METHODS:Bilateral carotid-to-external jugular vein AVF were created. Two balloon-expandable tantalum stents (Strecker stent), two self-expanding n...

    journal_title:Investigative radiology

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    doi:10.1097/00004424-199901000-00004

    authors: Schellhammer F,Wahkloo AK,Nagursky H,Schumacher M

    更新日期:1999-01-01 00:00:00

  • First-pass evaluation of myocardial output during dipyridamole stress using turbo-FLASH magnetic resonance imaging.

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    pub_type: 杂志文章

    doi:10.1097/00004424-199611000-00003

    authors: Tello R,Hartnell GG,Hill TC,Cerel A,Finn JP,Kamalesh M,Cohen M,Lewis S

    更新日期:1996-11-01 00:00:00

  • The uptake of manganese dipyridoxal-diphosphate by chemically induced hepatocellular carcinoma in rats. A correlation between contrast-media-enhanced magnetic resonance imaging, tumor differentiation, and vascularization.

    abstract:OBJECTIVES AND RATIONALE:Negative enhancement of implanted liver tumors has been achieved in preclinical studies on manganese dipyridoxal-diphosphate (Mn-DPDP), a new hepatobiliary specific contrast agent for magnetic resonance imaging (MRI). The authors investigated the effects of Mn-DPDP on primary liver cancer and i...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199306000-00011

    authors: Ni Y,Marchal G,Zhang X,Van Hecke P,Michiels J,Yu J,Rummeny E,Lodemann KP,Baert AL

    更新日期:1993-06-01 00:00:00

  • Magnetic resonance evaluation of regional left ventricular function. Effect of through-plane motion.

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    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199209000-00004

    authors: Pattynama PM,Doornbos J,Hermans J,van der Wall EE,de Roos A

    更新日期:1992-09-01 00:00:00

  • Evaluation of diffusion-weighted MR imaging at inclusion in an active surveillance protocol for low-risk prostate cancer.

    abstract:PURPOSE:We aimed to determine whether diffusion-weighted magnetic resonance imaging, by means of the apparent diffusion coefficient (ADC), is able to guide magnetic resonance-guided biopsy in patients fit for active surveillance (AS) and identify patients harboring high-grade Gleason components not suitable for AS. MA...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31827b711e

    authors: Somford DM,Hoeks CM,Hulsbergen-van de Kaa CA,Hambrock T,Fütterer JJ,Witjes JA,Bangma CH,Vergunst H,Smits GA,Oddens JR,van Oort IM,Barentsz JO,MR-PRIAS Collaboration Group.

    更新日期:2013-03-01 00:00:00

  • Breast stereotactic core biopsy washings: abundant cell samples from clinically occult lesions for flow cytometric DNA analysis.

    abstract:RATIONALE AND OBJECTIVES:The object of this study was to determine by flow cytometry the cellular and DNA content of the washings of core biopsy samples and needles obtained during stereotactic core biopsies of clinically occult suspicious lesions. METHODS:Fourteen-gauge core multipass biopsy inner-needle saline washi...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199801000-00008

    authors: Stomper PC,Budnick RM,Stewart CC

    更新日期:1998-01-01 00:00:00

  • Microangiographic anatomy of the cat's eye.

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    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-197501000-00007

    authors: Rothman SL,Kier EL,Deuker DK

    更新日期:1975-01-01 00:00:00

  • Pyrroxamide, a nonionic nitroxyl spin label contrast agent for magnetic resonance imaging. Mutagenesis and cell survival.

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    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198808000-00013

    authors: Gordon DG,Brasch RC,Ogan MD,Deen D

    更新日期:1988-08-01 00:00:00

  • Opacification phase effects of angiographic contrast medium on left ventricular size and function: influence of initial ventricular volume and the pericardium.

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    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198209000-00009

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    更新日期:1982-09-01 00:00:00

  • Lactate accumulation in ischemic- and anoxic-isolated rat hearts assessed by H-1 spectroscopy.

    abstract::Proton magnetic resonance (MR) spectroscopy with homonuclear editing was used to assess lactate accumulation in ischemic and anoxic hearts perfused according to the Langendorff method. An increase in the lactate signal was observed after 5 minutes of ischemia and after 10 to 20 minutes of anoxia. This study demonstrat...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198708000-00004

    authors: Richards TL,Terrier F,Sievers RE,Lipton MJ,Moseley ME,Higgins CB

    更新日期:1987-08-01 00:00:00

  • Magnetic resonance imaging in a spinal abscess model. Preliminary report.

    abstract:RATIONAL AND OBJECTIVES:Magnetic resonance (MR) scan technique and lesion detectability were evaluated using a newly developed spinal abscess model in the New Zealand White rabbit. METHODS:To create the lesion, an epidural needle was inserted under fluoroscopic guidance in the lumbar region and advanced to penetrate t...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199804000-00008

    authors: Runge VM,Williams NM,Lee C,Timoney JF

    更新日期:1998-04-01 00:00:00

  • Experimental renal papillary necrosis in rats: microangiographic and tubular micropuncture injection studies.

    abstract::Proposed causes of renal papillary necrosis (RPN) include tubular toxicity due to hyperconcentration of toxins in the renal medulla and vasoconstriction of medullary vessels with ischemic necrosis. The authors studied these mechanisms in bromoethylamine hydrobromide-induced RPN in rats by microvascular and tubular mic...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198103000-00006

    authors: Cuttino JT Jr,Goss FU,Clark RL,Marr MC

    更新日期:1981-03-01 00:00:00

  • Delayed Gadolinium Leakage in Ocular Structures: A Potential Marker for Age- and Vascular Risk Factor-Related Small Vessel Disease?

    abstract:BACKGROUND:Gadolinium leakage in ocular structures (GLOS) was recently observed in fluid-attenuated inversion recovery (FLAIR) images obtained the day after an initial gadolinium injection in stroke patients. The specificity of GLOS to stroke and its mechanisms remain unclear. OBJECTIVE:We investigated the factors ass...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000757

    authors: Galmiche C,Moal B,Marnat G,Sagnier S,Schweitzer C,Dousset V,Sibon I,Tourdias T

    更新日期:2021-01-19 00:00:00

  • Patient choice and nonionic contrast media.

    abstract:RATIONALE AND OBJECTIVES:Because of the greatly increased cost of nonionic, low-osmolar contrast material, some practitioners reserve its use for patients at high risk for an adverse contrast reaction. The authors attempt to evaluate the proportion of low-risk outpatients--when offered a choice between the more expensi...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199304000-00008

    authors: Hopper KD,Matthews YL

    更新日期:1993-04-01 00:00:00

  • An experimental evaluation of central vs. peripheral injection for intravenous digital subtraction angiography (IV-DSA).

    abstract::At a given radiation dosage and field of view, five variables are under meaningful control for intravenous digital subtraction angiography (IV-DSA): concentration and quantity of contrast media injected, volume of injectate, rate of injection, and site of injection. Some controversy exists regarding the selection of a...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198401000-00007

    authors: Rubin DL,Burbank FH,Bradley BR,Brody WR

    更新日期:1984-01-01 00:00:00

  • Magnetic resonance imaging and histologic findings of experimental cerebral fat embolism.

    abstract:RATIONALE AND OBJECTIVES:The purpose of this study was to determine whether cerebral fat embolism demonstrated reversible or irreversible findings in magnetic resonance (MR) imaging over time and to compare the features in MR images with histologic findings in a cat model. MATERIALS AND METHODS:MR images were obtained...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/01.rli.0000077055.48406.e2

    authors: Kim HJ,Lee CH,Lee SH,Moon TY

    更新日期:2003-10-01 00:00:00

  • Ultrasound Time-Harmonic Elastography of the Pancreas: Reference Values and Clinical Feasibility.

    abstract:OBJECTIVES:Pancreatic ductal adenocarcinoma (PDAC) is a very aggressive tumor with a very low 5-year survival rate of 8%. The aims of this study are to determine reference values and physiologic confounders in healthy pancreas and to assess the diagnostic accuracy of ultrasound time-harmonic elastography (THE) in the d...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000638

    authors: Burkhardt C,Tzschätzsch H,Schmuck R,Bahra M,Jürgensen C,Pelzer U,Hamm B,Braun J,Sack I,Marticorena Garcia SR

    更新日期:2020-05-01 00:00:00

  • Ultra-low-dose, time-resolved contrast-enhanced magnetic resonance angiography of the carotid arteries at 3.0 tesla.

    abstract:PURPOSE:To determine whether time-resolved magnetic resonance angiography (TR-MRA) with ultra-low-dose gadolinium chelate (1.5-3.0 mL) can reliably detect or rule out hemodynamically significant disease in the carotid-vertebral artery territory. MATERIALS AND METHODS:Hundred consecutive patients (62 women, 38 men, mea...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e31819ca048

    authors: Lohan DG,Tomasian A,Saleh RS,Singhal A,Krishnam MS,Finn JP

    更新日期:2009-04-01 00:00:00

  • Improving CT-Based PET Attenuation Correction in the Vicinity of Metal Implants by an Iterative Metal Artifact Reduction Algorithm of CT Data and Its Comparison to Dual-Energy-Based Strategies: A Phantom Study.

    abstract:OBJECTIVE:The aim of this study was to evaluate the potential of iterative metal artifact reduction (IMAR) for the improvement of computed tomography (CT)-based position emission tomography (PET) attenuation correction in the vicinity of metal implants and compare it with dual-energy-based metal artifact reduction stra...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0000000000000306

    authors: Schabel C,Gatidis S,Bongers M,Hüttig F,Bier G,Kupferschlaeger J,Bamberg F,la Fougère C,Nikolaou K,Pfannenberg C

    更新日期:2017-01-01 00:00:00

  • Comparative transmetallation kinetics and thermodynamic stability of gadolinium-DTPA bis-glucosamide and other magnetic resonance imaging contrast media.

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    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199610000-00003

    authors: Puttagunta NR,Gibby WA,Puttagunta VL

    更新日期:1996-10-01 00:00:00

  • Systematic evaluation and increased structure in a radiology elective.

    abstract::Diagnostic radiology is expanding, playing an increasingly central role in patient care, which heightens the importance of radiology teaching in undergraduate medical education. This study examined the impact of increased structure and systematic evaluation on student performance in a radiology elective. The evaluatio...

    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198505000-00003

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    更新日期:1985-05-01 00:00:00

  • Detection and characterization of focal liver lesions: a Japanese phase III, multicenter comparison between gadoxetic acid disodium-enhanced magnetic resonance imaging and contrast-enhanced computed tomography predominantly in patients with hepatocellular

    abstract:OBJECTIVES:To prospectively evaluate the safety and efficacy of combined unenhanced and gadoxetic acid disodium (Gd-EOB-DTPA)-enhanced magnetic resonance (MR) imaging compared with unenhanced MR imaging and triphasic contrast-enhanced spiral computed tomography (CT) for the detection and characterization of focal liver...

    journal_title:Investigative radiology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/RLI.0b013e3181caea5b

    authors: Ichikawa T,Saito K,Yoshioka N,Tanimoto A,Gokan T,Takehara Y,Kamura T,Gabata T,Murakami T,Ito K,Hirohashi S,Nishie A,Saito Y,Onaya H,Kuwatsuru R,Morimoto A,Ueda K,Kurauchi M,Breuer J

    更新日期:2010-03-01 00:00:00

  • Semiautomatic lymph node segmentation in multislice computed tomography: impact of slice thickness on segmentation quality, measurement precision, and interobserver variability.

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    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e3181c443e1

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  • Multiplanar reconstruction in magnetic resonance evaluation of the knee. Comparison with film magnetic resonance interpretation.

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    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199302000-00011

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    journal_title:Investigative radiology

    pub_type: 临床试验,杂志文章,随机对照试验

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    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198906001-00005

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    更新日期:1989-06-01 00:00:00

  • Ultrasound analysis of tongue, hyoid, and larynx activity during swallowing.

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    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-198403000-00003

    authors: Shawker TH,Sonies B,Hall TE,Baum BF

    更新日期:1984-03-01 00:00:00

  • Altered cerebrovenous drainage in patients with migraine as assessed by phase-contrast magnetic resonance imaging.

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    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/RLI.0b013e318210ecf5

    authors: Koerte IK,Schankin CJ,Immler S,Lee S,Laubender RP,Grosse C,Eftimov L,Milde-Busch A,Reiser M,Straube A,Heinen F,Alperin N,Ertl-Wagner B

    更新日期:2011-07-01 00:00:00

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    journal_title:Investigative radiology

    pub_type: 杂志文章

    doi:10.1097/00004424-199903000-00014

    authors: Calmet C,Vincensini D,Bonnet J,Bertino C,Catala A,Martinez M,Joffre F

    更新日期:1999-03-01 00:00:00