Methicillin-resistant Staphylococcus aureus: from the hospital to the community.

abstract：:Ventilator-associated pneumonia (VAP), an infection of the lower respiratory tract which occurs in association with mechanical ventilation, is one of the most common causes of nosocomial infection in the intensive care unit (ICU). VAP causes significant morbidity and mortality in critically ill patients including incr...

journal_title：Current infectious disease reports

authors： Waters B,Muscedere J

更新日期：2015-08-01 00:00:00

abstract：:The deadly combination of tuberculosis (TB) and human immunodeficiency virus (HIV) currently ravaging the world, taking a toll of about 0.35 million people every year, is one of the major public health crises of the decade. Throughout the course of HIV infection, the risk of acquisition, reactivation, and reinfection ...

journal_title：Current infectious disease reports

authors： Varghese GM,Janardhanan J,Ralph R,Abraham OC

更新日期：2013-02-01 00:00:00

abstract：:Lower respiratory tract infections (LRTIs) are a global burden to public health and are frequently caused by respiratory viruses. Advances in molecular diagnostic techniques have allowed the identification of previously undetected viral pathogens and have improved our understanding of respiratory virus infections. Her...

journal_title：Current infectious disease reports

authors： Ren L,Xiang Z,Guo L,Wang J

更新日期：2012-06-01 00:00:00

abstract：:Community-acquired pneumonia (CAP) is one of the most common causes of morbidity and mortality in elderly and children. Vitamin C is known as a physiological antioxidant, regulating innate immune system in the lung. Vitamin C has been used to prevent and treat CAP. However, the use of vitamin C for preventing and trea...

journal_title：Current infectious disease reports

authors： Li Y,Li G

更新日期：2016-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this article is to perform a systematic review over the past 5 years on the role and effectiveness of clinical decision support systems (CDSSs) on antibiotic stewardship. RECENT FINDINGS:CDDS interventions found a significant impact on multiple outcomes relevant to antibiotic stewardsh...

journal_title：Current infectious disease reports

authors： Rittmann B,Stevens MP

更新日期：2019-07-24 00:00:00

abstract：:Three newer oral antifungal agents, itraconazole, terbinafine and fluconazole, have revolutionized treatment of superficial mycoses. The tissue pharmacokinetics of itraconazole and terbinafine allow much shorter courses of therapy- with higher efficacy-in the treatment of onychomycosis, compared to other oral agents. ...

journal_title：Current infectious disease reports

authors： Del Rosso JQ

更新日期：2000-10-01 00:00:00

abstract：:Noroviruses are among the most common cause of diarrhea in transplant recipients. The clinical spectrum of norovirus infection after transplant is increasingly being recognized. As substantial morbidity is now associated with norovirus infections in this population; the quest for rapid diagnostic modalities and newer ...

journal_title：Current infectious disease reports

authors： Angarone MP,Sheahan A,Kamboj M

更新日期：2016-06-01 00:00:00

abstract：:There is strong evidence that preoperative nasal S. aureus screening/decolonization will significantly reduce surgical site infections (SSIs) after joint prostheses implantation. There is some evidence that antibiotic-containing bone cement may lower SSI rates. Timely administration of perioperative systemic antibioti...

journal_title：Current infectious disease reports

authors： Vonberg RP,Gastmeier P

更新日期：2012-10-01 00:00:00

abstract：:The first description of acute respiratory distress syndrome (ARDS) in adults appeared in 1967 and was characterized by dyspnea, hypoxemia, diffuse alveolar infiltrates, and reduced respiratory system compliance. ARDS and acute lung injury (ALI) syndrome have no specific treatment, only supportive care: treating the u...

journal_title：Current infectious disease reports

authors： Chiumello D,Cressoni M

更新日期：2009-09-01 00:00:00

abstract：:About 1% of all patients with end-stage renal disease in the United States are infected with HIV. With the introduction of highly active antiretroviral therapy (HAART), HIV death rates have declined 80%, and chronic diseases resulting from HIV have replaced opportunistic infections as the leading cause of death among ...

journal_title：Current infectious disease reports

authors： Locke JE,Segev DL

更新日期：2010-01-01 00:00:00

abstract：:High-risk human papillomaviruses (HPVs) are now recognized as the etiologic agents of invasive cervical cancer, a major cancer in women. A single HPV type (type 16) is responsible for about 50% of the cancers. The major capsid protein of papillomaviruses, L1, when expressed by recombinant DNA technology, has the intri...

journal_title：Current infectious disease reports

authors： Gravitt PE,Shah KV

更新日期：2005-03-01 00:00:00

abstract：:The immune reconstitution inflammatory syndrome (IRIS) is a well-described phenomenon in HIV-infected patients following initiation of antiretroviral therapy and can lead to significant morbidity and mortality in some patients. Risk for IRIS is enhanced in those with low CD4 counts and preexisting opportunistic infect...

journal_title：Current infectious disease reports

authors： Armstrong WS

更新日期：2013-02-01 00:00:00

abstract：:Bacterial meningitis is a complex disorder in which neurologic injury is caused, in part, by the causative organism and, in part, by the host's own inflammatory response. In studies of experimental bacterial meningitis, adjuvant treatment with corticosteroids, specifically dexamethasone, has beneficial effects. On the...

journal_title：Current infectious disease reports

authors： van de Beek D,de Gans J

更新日期：2005-07-01 00:00:00

abstract：:Streptococcus bovis is a rare, but important cause of bacterial meningitis in children. Since its discovery in the early 1970s, the pathogen has undergone multiple taxonomic changes producing four distinct subspecies today, the most prevalent of which is S. gallolyticus subsp pasteurianus in infants and children. Whil...

journal_title：Current infectious disease reports

authors： Hede SV

更新日期：2016-03-01 00:00:00

abstract：:Acute otitis media (AOM), when associated with a bulging or full tympanic membrane, has a bacterial etiology in more than 90% of cases. Not infrequently, the organisms present express resistance mechanisms to commonly prescribed antibiotic therapy. Tympanocentesis is a procedure advocated by several national guideline...

journal_title：Current infectious disease reports

authors： Pichichero ME,Wright T

更新日期：2006-05-01 00:00:00

abstract：:Primary infection of humans with varicella zoster virus (VZV) causes varicella (chickenpox), after which the virus becomes latent in cranial nerve ganglia, dorsal root ganglia and autonomic ganglia along the entire neuraxis. As VZV-specific cell-mediated immunity declines in elderly and immunocompromised individuals, ...

journal_title：Current infectious disease reports

authors： Nagel MA,Gilden D

更新日期：2014-06-01 00:00:00

abstract：:Antiretroviral therapy (ART) does not eliminate HIV-1 from latently infected reservoirs, and this remains the critical obstacle to the eradication of infection. Although ART is effective in suppressing viral load, life-long ART is burdensome in many respects. Given expanding numbers of HIV-infected individuals on ART ...

journal_title：Current infectious disease reports

authors： Margolis DM

更新日期：2014-03-01 00:00:00

abstract：:Neuroimaging studies have revealed that neurocysticercosis is a major cause of neurologic disease in most developing countries and is an emerging disease in industrialized areas. Patients with neurocysticercosis present mainly with seizures (parenchymal form) or intracranial hypertension (ventricular/subarachnoid form...

journal_title：Current infectious disease reports

authors： White AC,Garcia HH

更新日期：1999-12-01 00:00:00

abstract：:Transmissible spongiform encephalopathies (TSEs) are a group of progressive, fatal neurodegenerative disorders that share a common spongiform histopathology. TSEs may be transmitted in a sporadic, familial, iatrogenic, or zoonotic fashion. The putative infectious agent of TSE, the prion, represents a novel paradigm of...

journal_title：Current infectious disease reports

authors： Janka J,Maldarelli F

更新日期：2004-08-01 00:00:00

abstract：:Although highly active antiretroviral therapy suppresses HIV replication resulting in extraordinary clinical benefits, toxicity, adherence difficulties, and the monetary cost of medications limit the long-term effectiveness and availability of therapy for many HIV-infected individuals. Strategies to interrupt therapy ...

journal_title：Current infectious disease reports

authors： Dybul M

更新日期：2002-04-01 00:00:00

abstract：:Chikungunya virus (CHIKV) is an alphavirus transmitted by mosquitoes, mostly Aedes aegypti and Aedes albopictus. After half a century of focal outbreaks of acute febrile polyarthralgia in Africa and Asia, the disease unexpectedly spread in the past decade with large outbreaks in Africa and around the Indian Ocean and ...

journal_title：Current infectious disease reports

authors： Simon F,Javelle E,Oliver M,Leparc-Goffart I,Marimoutou C

更新日期：2011-06-01 00:00:00

abstract：:Increases in sexually transmitted diseases (STDs) among men who have sex with men (MSM) have coincided with recent increases in sexual risk behaviors across the United States and Europe. The identification of same-sex sexual risk behavior in men and the subsequent risk for certain bacterial and viral infections requir...

journal_title：Current infectious disease reports

authors： Klausner JD,Wong W

更新日期：2003-04-01 00:00:00

abstract：:Heavily pretreated HIV-infected patients with multidrug-resistant virus remain a clinical challenge to the treating physician. While the goal of therapy in such patients is still controversial, sustained immunologic and clinical benefit have only been demonstrated with complete suppression of plasma viral load below d...

journal_title：Current infectious disease reports

authors： Montaner JS,Harris M

更新日期：2002-06-01 00:00:00

abstract：:Colonization with Staphylococcus aureus is a risk factor for invasive S. aureus infections. Intranasal mupirocin has effectively eradicated S. aureus colonization and appears to prevent S. aureus nosocomial infections in some patient populations. In hospitals and communities where mupirocin use has been widespread, re...

journal_title：Current infectious disease reports

authors： Polgreen PM,Herwaldt LA

更新日期：2004-12-01 00:00:00

abstract：:Hepatitis delta virus (HDV) is a unique human virus, showing similarities with plant viroids. Although impressive knowledge on virus structure and replication has been achieved, several questions like HBV/HDV interaction and post translational modifications of HD antigens remain to be answered. Potential targets for t...

journal_title：Current infectious disease reports

authors： Niro GA,Smedile A

更新日期：2012-02-01 00:00:00

abstract：:Group A streptococcus is a widespread human pathogen that causes a broad spectrum of human disease. The persistent high burden and severity of illness in developing and industrialized countries speaks to the need for a safe and effective vaccine. Modern approaches to vaccine construction include M protein type-specifi...

journal_title：Current infectious disease reports

authors： Kotloff KL

更新日期：2008-05-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a significant cause of chronic liver disease with substantial long-term sequelae. Until very recently, therapies to cure HCV were hindered by high nonresponse rates and severe side effects. The first-generation protease inhibitor-containing regimens provided superior cure rates for...

journal_title：Current infectious disease reports

authors： Moore C,Levitsky J

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:This review attempts to understand the reasons for the successes and failures of the two novel strategies that have slowly begun to emerge as potential counters for anti-malarial drug resistance-"Triple Combination Therapy" and "Drug Cycling." RECENT FINDINGS:Recent reports have suggested that increa...

journal_title：Current infectious disease reports

authors： Dipanjan B,Shivaprakash G,Balaji O

更新日期：2017-07-01 00:00:00

abstract：PURPOSE OF REVIEW:Post-transplant infections present a formidable challenge to the physician due to their varied presentation. Many of these infections begin by inoculation following skin compromise or disseminate to the skin hematogenously, making cutaneous manifestations of infection an important diagnostic clue in t...

journal_title：Current infectious disease reports

authors： Pettit CJ,Mazurek K,Kaffenberger B

更新日期：2018-05-22 00:00:00

abstract：:Myocarditis is an acquired form inflammatory heart muscle disease, manifested as acute and chronic conditions. While many etiologies have been reported, the most common cause of this disease is infection, primarily viral. Typically, the specific causative agent(s) and mechanism(s) are elusive. Over the past several ye...

journal_title：Current infectious disease reports

authors： Bowles NE,Towbin JA

更新日期：2000-08-01 00:00:00