Abstract:
:Three newer oral antifungal agents, itraconazole, terbinafine and fluconazole, have revolutionized treatment of superficial mycoses. The tissue pharmacokinetics of itraconazole and terbinafine allow much shorter courses of therapy- with higher efficacy-in the treatment of onychomycosis, compared to other oral agents. Itraconazole pulse dosing and terbinafine daily dosing have shown comparable efficacy against dermatophyte onychomycosis; similar itraconazole regimens have been effective against nondermatophyte infections. Refractory clinical patterns of nail disease appear to be more responsive to oral antifungal therapy when combined with adjunctive therapy, such as debridement. These agents are effective against cutaneous dermatophytosis, with shorter treatment regimens. Tinea versicolor may be treated with a single-dose, intermittent, or daily regimen of an oral azole agent, depending on the drug selected. These newer oral antifungal agents have been proven effective against tinea capitis; effective regimens are shorter than those for griseofulvin. The safety profile of these newer agents has been very favorable.
journal_name
Curr Infect Dis Repjournal_title
Current infectious disease reportsauthors
Del Rosso JQdoi
10.1007/s11908-000-0074-0keywords:
subject
Has Abstractpub_date
2000-10-01 00:00:00pages
438-445issue
5eissn
1523-3847issn
1534-3146journal_volume
2pub_type
杂志文章abstract:PURPOSE OF REVIEW:This review attempts to understand the reasons for the successes and failures of the two novel strategies that have slowly begun to emerge as potential counters for anti-malarial drug resistance-"Triple Combination Therapy" and "Drug Cycling." RECENT FINDINGS:Recent reports have suggested that increa...
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pub_type: 杂志文章,评审
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journal_title:Current infectious disease reports
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doi:10.1007/s11908-010-0153-9
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-005-0022-0
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journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0601-x
更新日期:2017-09-19 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-015-0472-y
更新日期:2015-04-01 00:00:00
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journal_title:Current infectious disease reports
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journal_title:Current infectious disease reports
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更新日期:2003-08-01 00:00:00
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journal_title:Current infectious disease reports
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doi:10.1007/s11908-003-0050-6
更新日期:2003-04-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-999-0031-5
更新日期:1999-08-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-005-0044-7
更新日期:2005-11-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-005-0007-z
更新日期:2005-09-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-001-0090-8
更新日期:2001-12-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s11908-007-0031-2
更新日期:2007-05-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0600-y
更新日期:2017-09-23 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-006-0052-2
更新日期:2006-09-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-002-0078-z
更新日期:2002-06-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-999-0055-x
更新日期:1999-12-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
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更新日期:2003-10-01 00:00:00
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更新日期:2012-06-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-009-0045-z
更新日期:2009-07-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-000-0090-0
更新日期:2000-02-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
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更新日期:2015-03-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
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更新日期:2019-03-02 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-006-0034-4
更新日期:2006-01-01 00:00:00
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更新日期:2018-05-05 00:00:00
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doi:10.1007/s11908-014-0413-1
更新日期:2014-08-01 00:00:00
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更新日期:1999-06-01 00:00:00