A 2015 Update on Ventilator-Associated Pneumonia: New Insights on Its Prevention, Diagnosis, and Treatment.

abstract：:There is strong evidence that preoperative nasal S. aureus screening/decolonization will significantly reduce surgical site infections (SSIs) after joint prostheses implantation. There is some evidence that antibiotic-containing bone cement may lower SSI rates. Timely administration of perioperative systemic antibioti...

journal_title：Current infectious disease reports

authors： Vonberg RP,Gastmeier P

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:This review attempts to understand the reasons for the successes and failures of the two novel strategies that have slowly begun to emerge as potential counters for anti-malarial drug resistance-"Triple Combination Therapy" and "Drug Cycling." RECENT FINDINGS:Recent reports have suggested that increa...

journal_title：Current infectious disease reports

authors： Dipanjan B,Shivaprakash G,Balaji O

更新日期：2017-07-01 00:00:00

abstract：:Bacterial meningitis is a complex disorder in which neurologic injury is caused, in part, by the causative organism and, in part, by the host's own inflammatory response. In studies of experimental bacterial meningitis, adjuvant treatment with corticosteroids, specifically dexamethasone, has beneficial effects. On the...

journal_title：Current infectious disease reports

authors： van de Beek D,de Gans J

更新日期：2005-07-01 00:00:00

abstract：:Community-acquired pneumonia (CAP) is one of the most common causes of morbidity and mortality in elderly and children. Vitamin C is known as a physiological antioxidant, regulating innate immune system in the lung. Vitamin C has been used to prevent and treat CAP. However, the use of vitamin C for preventing and trea...

journal_title：Current infectious disease reports

authors： Li Y,Li G

更新日期：2016-08-01 00:00:00

abstract：:The first description of acute respiratory distress syndrome (ARDS) in adults appeared in 1967 and was characterized by dyspnea, hypoxemia, diffuse alveolar infiltrates, and reduced respiratory system compliance. ARDS and acute lung injury (ALI) syndrome have no specific treatment, only supportive care: treating the u...

journal_title：Current infectious disease reports

authors： Chiumello D,Cressoni M

更新日期：2009-09-01 00:00:00

abstract：:Transmissible spongiform encephalopathies (TSEs) are a group of progressive, fatal neurodegenerative disorders that share a common spongiform histopathology. TSEs may be transmitted in a sporadic, familial, iatrogenic, or zoonotic fashion. The putative infectious agent of TSE, the prion, represents a novel paradigm of...

journal_title：Current infectious disease reports

authors： Janka J,Maldarelli F

更新日期：2004-08-01 00:00:00

abstract：:A broad range of disorders can cause inflammation of the thyroid gland. True thyroid infections are rare and can result from a variety of microorganisms, of which bacteria are the most common. Other rarer pathogens include fungi, parasites, and viruses. Gram-positive bacteria, especially staphylococci, predominate as ...

journal_title：Current infectious disease reports

authors： Shah SS,Baum SG

更新日期：2000-04-01 00:00:00

abstract：:Urinary tract infection (UTI) is a common clinical syndrome in women. Most UTIs are caused by Escherichia coli. UTI has become a productive and accessible model system for studying the molecular details of how bacteria interact with mucosal surfaces and the nature of the host response. Important advances in the past y...

journal_title：Current infectious disease reports

authors： Stapleton AE

更新日期：2006-11-01 00:00:00

abstract：:Oral triazole therapy is well established for the treatment of invasive aspergillosis (IPA), allergic aspergillosis (ABPA), and chronic pulmonary aspergillosis (CPA), and is often long-term. Resistance to triazole azole antifungal drugs in Aspergillus fumigatus is now a major clinical problem in a number of European l...

journal_title：Current infectious disease reports

authors： Bowyer P,Moore CB,Rautemaa R,Denning DW,Richardson MD

更新日期：2011-12-01 00:00:00

abstract：:Chlamydia psittaci, Chlamydia pneumoniae, and Mycoplasma pneumoniae are a group of respiratory pathogens that have similar pulmonary and extrapulmonary manifestations. Recent studies suggest that C. pneumoniae and M. pneumoniae may play a role in the pathogenesis of asthma, but further studies are needed to delineate ...

journal_title：Current infectious disease reports

authors： Atmar RL

更新日期：1999-04-01 00:00:00

abstract：Purpose of Review:In December 2019, outbreaks of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected pneumonia patients were discovered in Wuhan City, Hubei Province, China. With the spread of the epidemic, new cases have been found in other regions of China and abroad. This review summarizes the curr...

journal_title：Current infectious disease reports

authors： Wang Y,Wang L,Li X,Gong Z

更新日期：2020-01-01 00:00:00

abstract：:Pulmonary nocardiosis is an uncommon but serious infection that is increasingly found in immunosuppressed persons, especially transplant recipients and persons with AIDS. The Nocardia species are denizens of soil and decaying plants that gain entry to humans through inhalation or inoculation. Pulmonary nocardiosis typ...

journal_title：Current infectious disease reports

authors： Baracco GJ,Dickinson GM

更新日期：2001-06-01 00:00:00

abstract：:The outcome for HIV-infected patients with cancer has dramatically improved in the highly active antiretroviral therapy (HAART) era, probably due to improvements in immune status and bone marrow function that allow the possibility of increased drug-dose intensity with a higher complete remission rate. Although data re...

journal_title：Current infectious disease reports

authors： Rosso R,Di Biagio A,Viscoli C

更新日期：2008-05-01 00:00:00

abstract：:Streptococcus bovis is a rare, but important cause of bacterial meningitis in children. Since its discovery in the early 1970s, the pathogen has undergone multiple taxonomic changes producing four distinct subspecies today, the most prevalent of which is S. gallolyticus subsp pasteurianus in infants and children. Whil...

journal_title：Current infectious disease reports

authors： Hede SV

更新日期：2016-03-01 00:00:00

abstract：:Hepatic failure due to hepatitis C is the leading indicator for orthotopic liver transplantation (OLT) in the United States. Unfortunately, recurrent hepatitis C virus infection is essentially universal following orthotopic liver transplantation. Although significant advances have been made in the past decade for the ...

journal_title：Current infectious disease reports

authors： A Bobak D,Yadavalli G

更新日期：2002-04-01 00:00:00

abstract：:Although highly active antiretroviral therapy suppresses HIV replication resulting in extraordinary clinical benefits, toxicity, adherence difficulties, and the monetary cost of medications limit the long-term effectiveness and availability of therapy for many HIV-infected individuals. Strategies to interrupt therapy ...

journal_title：Current infectious disease reports

authors： Dybul M

更新日期：2002-04-01 00:00:00

abstract：:Diarrhea is one of the most common health problems among travelers. Although enterotoxigenic Escherichia coli is implicated most commonly, enteroaggregative E. coli has recently been described as a major pathogen. Shigella, Campylobacter, and Salmonella organisms are less common causes of acute diarrhea, and intestina...

journal_title：Current infectious disease reports

authors： Cheng AC,Thielman NM

更新日期：2002-02-01 00:00:00

abstract：:Myocarditis is an acquired form inflammatory heart muscle disease, manifested as acute and chronic conditions. While many etiologies have been reported, the most common cause of this disease is infection, primarily viral. Typically, the specific causative agent(s) and mechanism(s) are elusive. Over the past several ye...

journal_title：Current infectious disease reports

authors： Bowles NE,Towbin JA

更新日期：2000-08-01 00:00:00

abstract：:The deadly combination of tuberculosis (TB) and human immunodeficiency virus (HIV) currently ravaging the world, taking a toll of about 0.35 million people every year, is one of the major public health crises of the decade. Throughout the course of HIV infection, the risk of acquisition, reactivation, and reinfection ...

journal_title：Current infectious disease reports

authors： Varghese GM,Janardhanan J,Ralph R,Abraham OC

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to review therapies with new mechanisms of action for the treatment of HIV that are at least in phase 2 clinical trials. RECENT FINDINGS:There are several new mechanisms of action being represented within clinical development, including histone deacetylase (HDAC) inhibito...

journal_title：Current infectious disease reports

authors： Gravatt LAH,Leibrand CR,Patel S,McRae M

更新日期：2017-09-19 00:00:00

abstract：:Many data associate low protease inhibitor plasma concentrations with suboptimal virologic responses, whereas relatively few data associate high plasma concentrations with increased likelihood of toxicity. Knowledge of relationships between concentrations and virologic response is important because significant variabi...

journal_title：Current infectious disease reports

authors： Anderson PL,Fletcher CV

更新日期：2001-08-01 00:00:00

abstract：:Neisseria gonorrhoeae is a common cause of genitourinary sexually transmitted infections. N. gonorrhoeae is an obligate human pathogen that has evidence of tissue-specific host interactions and diverse extragenital manifestations of infection both in adult and pediatric populations. The clinical presentation of extrag...

journal_title：Current infectious disease reports

authors： Spencer SE,Bash MC

更新日期：2006-03-01 00:00:00

abstract：:Pyoderma gangrenosum (PG) is a rare cause of purulent vulvovaginal ulceration. Six recent cases of vulvovaginal pyoderma gangrenosum associated with rituximab are described. All cases were seen in the setting of rituximab used for the treatment of B cell non Hodgkin's lymphoma (NHL). Age range was 50-74; symptoms were...

journal_title：Current infectious disease reports

authors： Selva-Nayagam P,Fischer G,Hamann I,Sobel J,James C

更新日期：2015-05-01 00:00:00

abstract：:Immunization against the most common meningeal pathogens is the leading factor associated with decreased incidence of bacterial meningitis in countries where routine vaccination is available. This is most dramatically illustrated by the reduction in the incidence of Haemophilus influenzae type b meningitis. The incide...

journal_title：Current infectious disease reports

authors： Dery MA,Hasbun R

更新日期：2007-07-01 00:00:00

abstract：:Heavily pretreated HIV-infected patients with multidrug-resistant virus remain a clinical challenge to the treating physician. While the goal of therapy in such patients is still controversial, sustained immunologic and clinical benefit have only been demonstrated with complete suppression of plasma viral load below d...

journal_title：Current infectious disease reports

authors： Montaner JS,Harris M

更新日期：2002-06-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a significant cause of chronic liver disease with substantial long-term sequelae. Until very recently, therapies to cure HCV were hindered by high nonresponse rates and severe side effects. The first-generation protease inhibitor-containing regimens provided superior cure rates for...

journal_title：Current infectious disease reports

authors： Moore C,Levitsky J

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to discuss the unique pathways of biofilm formation utilized by respiratory pathogens and current and future therapeutic strategies to inhibit biofilm formation or eradicate established biofilm in the context of these pathogens. Both nonselective and selective strategies ...

journal_title：Current infectious disease reports

authors： Hamilos DL

更新日期：2019-03-02 00:00:00

abstract：:Cyclosporiasis is a food- and water-borne infection that affects healthy and immunocompromised individuals. Awareness of the disease has increased, and outbreaks continue to be reported among vulnerable hosts and now among local residents in endemic areas. Advances in molecular techniques have improved identification ...

journal_title：Current infectious disease reports

authors： Warren CA

更新日期：2009-03-01 00:00:00

abstract：:Increases in sexually transmitted diseases (STDs) among men who have sex with men (MSM) have coincided with recent increases in sexual risk behaviors across the United States and Europe. The identification of same-sex sexual risk behavior in men and the subsequent risk for certain bacterial and viral infections requir...

journal_title：Current infectious disease reports

authors： Klausner JD,Wong W

更新日期：2003-04-01 00:00:00

abstract：:Infectious myositis is defined as an infection of a skeletal muscle. Infectious myositis is most commonly caused by bacteria; however, a variety of viral, parasitic, and fungal agents may also cause myositis. The pathogenesis of nonbacterial infectious myositis is via direct or hematogenous infection of the musculatur...

journal_title：Current infectious disease reports

authors： Crum-Cianflone NF

更新日期：2010-09-01 00:00:00