Management of HIV-infected Patients with Multidrug-resistant Virus.

abstract：:Before the advent of antiretroviral therapy (ART), CMV retinitis was a common, debilitating opportunistic infection in the HIV-infected population. ART has had such a favorable impact on the prevention and management of CMV retinitis that it can be considered in some ways to be CMV therapy. Currently available CMV dir...

journal_title：Current infectious disease reports

authors： Barrett L,Walmsley S

更新日期：2012-08-01 00:00:00

abstract：:In most high-income countries, fewer children now acquire meningitis, and many of those who do will survive. Globally, however, meningitis still remains a significant cause of child morbidity and mortality. In this article, the authors review recent evidence on the morbidity faced by childhood survivors of bacterial m...

journal_title：Current infectious disease reports

authors： Hudson LD,Viner RM,Christie D

更新日期：2013-06-01 00:00:00

abstract：:The pathogenesis of vulvovaginal candidiasis, which is caused by Candida albicans, is poorly understood. Despite a strong protective role for cell-mediated immunity (CMI) against other mucosal candidal infections, numerous studies in humans and most animal models have revealed little to no role for CMI or other forms ...

journal_title：Current infectious disease reports

authors： Fidel PL

更新日期：2003-12-01 00:00:00

abstract：:Lower respiratory tract infections (LRTIs) are a global burden to public health and are frequently caused by respiratory viruses. Advances in molecular diagnostic techniques have allowed the identification of previously undetected viral pathogens and have improved our understanding of respiratory virus infections. Her...

journal_title：Current infectious disease reports

authors： Ren L,Xiang Z,Guo L,Wang J

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Community-acquired pneumonia (CAP) is the cause of a considerable burden of morbidity and mortality among HIV-infected patients. The purpose of this study was to review recent literature for epidemiological trends and management of CAP in HIV patients. RECENT FINDINGS:While the specific infectious et...

journal_title：Current infectious disease reports

authors： Almeida A,Boattini M

更新日期：2017-01-01 00:00:00

abstract：:Drotrecogin alfa (activated) (DrotAA) has been approved for therapy of severe sepsis and septic shock for 7 years, but controversy persists regarding efficacy and safety. Only a single randomized, controlled trial (Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis; PROWESS) has shown evidence...

journal_title：Current infectious disease reports

authors： Barie PS

更新日期：2008-09-01 00:00:00

abstract：:Candida species remain the most frequently isolated fungi in intensive care unit (ICU) patients with severe sepsis or septic shock. Delayed antifungal therapy in these patients is a recognized risk factor for mortality. However, the diagnosis of invasive candidiasis remains difficult and is frequently delayed. Clinica...

journal_title：Current infectious disease reports

authors： Allou N,Allyn J,Montravers P

更新日期：2011-10-01 00:00:00

abstract：:Patients with sepsis may require mechanical ventilation due to the acute respiratory distress syndrome (ARDS). It has become increasingly accepted that mechanical ventilation can contribute to lung injury in these patients. The modern concept of ventilator-induced lung injury is described in the context of alveolar ov...

journal_title：Current infectious disease reports

authors： Hess DR,Thompson BT

更新日期：2005-09-01 00:00:00

abstract：:The ability to predict efficacy and toxicity during antiretroviral therapy for HIV would be of obvious advantage. The substantial variability between patients in terms of bioavailability and distribution of current regimens is likely driven by genetic and environmental factors. Protease inhibitors and nucleoside/nucle...

journal_title：Current infectious disease reports

authors： Owen A

更新日期：2006-09-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Community-acquired pneumonia (CAP) is still associated with a large burden and causes significant morbidity and mortality. Besides universal vaccination and antibiotic treatment, statins as adjunctive therapy may also have a beneficial role in the prevention and treatment of CAP. Our goal from thi...

journal_title：Current infectious disease reports

authors： Batais MA,Khan AR,Bin Abdulhak AA

更新日期：2017-08-01 00:00:00

abstract：:Fungal endocarditis (FE) is an increasingly prevalent and devastating disease in today's highly advancing medical practice. With more patients receiving broad-spectrum antibiotics or invasive interventions including long-term central venous catheters or prosthetic heart valve placements, FE is increasingly reported. R...

journal_title：Current infectious disease reports

authors： Varghese GM,Sobel JD

更新日期：2008-07-01 00:00:00

abstract：:Acute otitis media (AOM), when associated with a bulging or full tympanic membrane, has a bacterial etiology in more than 90% of cases. Not infrequently, the organisms present express resistance mechanisms to commonly prescribed antibiotic therapy. Tympanocentesis is a procedure advocated by several national guideline...

journal_title：Current infectious disease reports

authors： Pichichero ME,Wright T

更新日期：2006-05-01 00:00:00

abstract：:Antipsychotics are generally distinguished as atypical and typical agents, which are indicated in the treatment of acute and chronic psychoses and other psychiatric disorders. In April 2005, the US Food and Drug Administration issued a warning about the increased risk of all-cause mortality associated with atypical an...

journal_title：Current infectious disease reports

authors： Trifirò G

更新日期：2011-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review attempts to understand the reasons for the successes and failures of the two novel strategies that have slowly begun to emerge as potential counters for anti-malarial drug resistance-"Triple Combination Therapy" and "Drug Cycling." RECENT FINDINGS:Recent reports have suggested that increa...

journal_title：Current infectious disease reports

authors： Dipanjan B,Shivaprakash G,Balaji O

更新日期：2017-07-01 00:00:00

abstract：:Although waterborne pathogens are relatively uncommon causes of cutaneous infections, these agents are being recognized with increasing frequency. Humans are exposed to water through a variety of recreational and occupational activities. Poor sanitary conditions in developing nations place the human populations at con...

journal_title：Current infectious disease reports

authors： Elko L,Rosenbach K,Sinnott J

更新日期：2003-10-01 00:00:00

abstract：:Urinary tract infection (UTI) is common in postmenopausal women; the estimated incidence ranges from 4% to 15%. The clinical presentation of UTI is somewhat different in postmenopausal older women than it is in younger women: postmenopausal women are less likely to report frequency, dysuria, hematuria, and fever, but ...

journal_title：Current infectious disease reports

authors： Foxman B

更新日期：1999-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to review therapies with new mechanisms of action for the treatment of HIV that are at least in phase 2 clinical trials. RECENT FINDINGS:There are several new mechanisms of action being represented within clinical development, including histone deacetylase (HDAC) inhibito...

journal_title：Current infectious disease reports

authors： Gravatt LAH,Leibrand CR,Patel S,McRae M

更新日期：2017-09-19 00:00:00

abstract：:In the United States each year, influenza accounts for an estimated 20,000 to 40,000 deaths, nearly 300,000 hospitalizations, and millions of days lost from work. In the past few years, there has been an explosion of information in the medical literature related to influenza. This paper reviews these latest developmen...

journal_title：Current infectious disease reports

authors： Neuzil KM

更新日期：2000-06-01 00:00:00

abstract：:Hepatitis delta virus (HDV) is a unique human virus, showing similarities with plant viroids. Although impressive knowledge on virus structure and replication has been achieved, several questions like HBV/HDV interaction and post translational modifications of HD antigens remain to be answered. Potential targets for t...

journal_title：Current infectious disease reports

authors： Niro GA,Smedile A

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The increase in drug-resistant community-acquired pneumonia (CAP) is an important problem all over the world. This article explores the current state of antimicrobial resistance of different bacteria that cause CAP and also assesses risk factors to identify those pathogens. RECENT FINDINGS:In the las...

journal_title：Current infectious disease reports

authors： Arancibia F,Ruiz M

更新日期：2017-03-01 00:00:00

abstract：:Rotaviruses are the most important cause of pediatric gastroenteritis worldwide. In August 1998, a new rotavirus vaccine was licensed for general use in the United States. However, 14 months later, the vaccine was withdrawn from the market because of serious gastrointestinal side effects. This paper discusses the need...

journal_title：Current infectious disease reports

authors： Coffin SE

更新日期：2000-02-01 00:00:00

abstract：:Infections due to community-associated methicillin---resistant Staphylococcus aureus (CA-MRSA) are becoming more prevalent. CA-MRSA infections have unique epidemiologic features and virulence factors. Compared with health care-associated MRSA (HA-MRSA), most CA-MRSA is clonal type USA300 or 400 and has the Staphylococ...

journal_title：Current infectious disease reports

authors： Paez A,Skiest D

更新日期：2008-03-01 00:00:00

abstract：:Reduction of microbial contamination of the hospital environment is a challenge, yet has potential impacts on infection prevention efforts. Fumigation and UV light devices for environmental cleaning have expanded into the health care setting with the goal of decontamination of difficult to clean or overlooked surfaces...

journal_title：Current infectious disease reports

authors： Doll M,Morgan DJ,Anderson D,Bearman G

更新日期：2015-09-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to discuss the unique pathways of biofilm formation utilized by respiratory pathogens and current and future therapeutic strategies to inhibit biofilm formation or eradicate established biofilm in the context of these pathogens. Both nonselective and selective strategies ...

journal_title：Current infectious disease reports

authors： Hamilos DL

更新日期：2019-03-02 00:00:00

abstract：:The immune reconstitution inflammatory syndrome (IRIS) is a well-described phenomenon in HIV-infected patients following initiation of antiretroviral therapy and can lead to significant morbidity and mortality in some patients. Risk for IRIS is enhanced in those with low CD4 counts and preexisting opportunistic infect...

journal_title：Current infectious disease reports

authors： Armstrong WS

更新日期：2013-02-01 00:00:00

abstract：:Pouchitis is an inflammatory complication after restorative proctocolectomy and ileal pouch-anal anastomosis (IPAA). IPAA is the surgical treatment of choice in patients with ulcerative colitis (UC) who require colectomy. Initial episodes of acute pouchitis generally respond to antibiotics but significant numbers of c...

journal_title：Current infectious disease reports

authors： Chowdhry S,Katz JA

更新日期：2014-12-01 00:00:00

abstract：:Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections have been reported with increasing frequency from many parts of the world. Most infections involve the skin and soft tissue structures, and CA-MRSA is now the most commonly identifiable cause of purulent skin and soft tissue infectio...

journal_title：Current infectious disease reports

authors： Abrahamian FM,Snyder EW

更新日期：2007-09-01 00:00:00

abstract：:Clinical toxinology is a specialized area of clinical medicine focused on the pathophysiology, diagnosis, treatment, and prevention of diseases caused by animal, plant, and fungal toxins. This review focuses on recent developments in snakebite. Snakebite is newly recognized as a Neglected Tropical Disease by the World...

journal_title：Current infectious disease reports

authors： White J

更新日期：2011-06-01 00:00:00

abstract：:Invasive fungal infection (IFI) is an important cause of morbidity and mortality in patients with hematologic malignancy, prolonged neutropenia, or after hematopoietic stem cell transplant. Antifungal prophylaxis prevents IFI in high-risk hematology patients. This article discusses recent developments in antifungal pr...

journal_title：Current infectious disease reports

authors： Wolf J,Slavin MA

更新日期：2009-11-01 00:00:00

abstract：:In recent years, substantial advances have been achieved in the treatment of mucormycosis. It is now clear that early initiation of therapy results in substantially better outcomes, underscoring the need to maintain a high index of suspicion and aggressively biopsy potential lesions. Increasing data support the need f...

journal_title：Current infectious disease reports

authors： Spellberg B,Ibrahim AS

更新日期：2010-11-01 00:00:00