Current role of activated protein C therapy for severe sepsis and septic shock.

abstract：:Primary infection of humans with varicella zoster virus (VZV) causes varicella (chickenpox), after which the virus becomes latent in cranial nerve ganglia, dorsal root ganglia and autonomic ganglia along the entire neuraxis. As VZV-specific cell-mediated immunity declines in elderly and immunocompromised individuals, ...

journal_title：Current infectious disease reports

authors： Nagel MA,Gilden D

更新日期：2014-06-01 00:00:00

abstract：:Prosthetic valve endocarditis (PVE) due to mycobacteria is a rare but frequently fatal complication that may occur early after the surgical procedure, or even years later. Infection has been described with both mechanical and biologic valvular prosthesis. The most commonly implicated mycobacterial species belong to th...

journal_title：Current infectious disease reports

authors： Bush LM,Paturi A,Chaparro-Rojas F,Perez MT

更新日期：2010-07-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a significant cause of chronic liver disease with substantial long-term sequelae. Until very recently, therapies to cure HCV were hindered by high nonresponse rates and severe side effects. The first-generation protease inhibitor-containing regimens provided superior cure rates for...

journal_title：Current infectious disease reports

authors： Moore C,Levitsky J

更新日期：2014-08-01 00:00:00

abstract：:The deadly combination of tuberculosis (TB) and human immunodeficiency virus (HIV) currently ravaging the world, taking a toll of about 0.35 million people every year, is one of the major public health crises of the decade. Throughout the course of HIV infection, the risk of acquisition, reactivation, and reinfection ...

journal_title：Current infectious disease reports

authors： Varghese GM,Janardhanan J,Ralph R,Abraham OC

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights current knowledge in travel-related neuroinfectious diseases, providing insight on approaches to prevention, diagnosis, and treatment of infections of the central nervous system (CNS) in travelers and immigrants. RECENT FINDINGS:Updates on travel vaccine recommendations includi...

journal_title：Current infectious disease reports

authors： Thompson H,Thakur K

更新日期：2017-10-03 00:00:00

abstract：:Urinary tract infection (UTI) is a common clinical syndrome in women. Most UTIs are caused by Escherichia coli. UTI has become a productive and accessible model system for studying the molecular details of how bacteria interact with mucosal surfaces and the nature of the host response. Important advances in the past y...

journal_title：Current infectious disease reports

authors： Stapleton AE

更新日期：2006-11-01 00:00:00

abstract：:With the causal link between specific types of human papillomavirus (HPV) and cervical cancer firmly established, efforts have turned to assessing the relative merits of offering HPV testing in screening, triage, and posttreatment management. Many unanswered questions remain, but a growing body of evidence supports a ...

journal_title：Current infectious disease reports

authors： Kulasingam SL,Koutsky LA

更新日期：2001-04-01 00:00:00

abstract：:The pathogenesis of vulvovaginal candidiasis, which is caused by Candida albicans, is poorly understood. Despite a strong protective role for cell-mediated immunity (CMI) against other mucosal candidal infections, numerous studies in humans and most animal models have revealed little to no role for CMI or other forms ...

journal_title：Current infectious disease reports

authors： Fidel PL

更新日期：2003-12-01 00:00:00

abstract：:It is well established that the immunological response to the seasonal trivalent influenza vaccine is attenuated in cancer patients. Furthermore, rates of seroprotection and seroconversion vary by malignancy type and are higher in patients with solid tumors, as compared either with those with hematologic malignancies ...

journal_title：Current infectious disease reports

authors： Baluch A,Pasikhova Y

更新日期：2013-12-01 00:00:00

abstract：:Chikungunya virus (CHIKV) is an alphavirus transmitted by mosquitoes, mostly Aedes aegypti and Aedes albopictus. After half a century of focal outbreaks of acute febrile polyarthralgia in Africa and Asia, the disease unexpectedly spread in the past decade with large outbreaks in Africa and around the Indian Ocean and ...

journal_title：Current infectious disease reports

authors： Simon F,Javelle E,Oliver M,Leparc-Goffart I,Marimoutou C

更新日期：2011-06-01 00:00:00

abstract：:Pouchitis is an inflammatory complication after restorative proctocolectomy and ileal pouch-anal anastomosis (IPAA). IPAA is the surgical treatment of choice in patients with ulcerative colitis (UC) who require colectomy. Initial episodes of acute pouchitis generally respond to antibiotics but significant numbers of c...

journal_title：Current infectious disease reports

authors： Chowdhry S,Katz JA

更新日期：2014-12-01 00:00:00

abstract：:Neisseria gonorrhoeae is a common cause of genitourinary sexually transmitted infections. N. gonorrhoeae is an obligate human pathogen that has evidence of tissue-specific host interactions and diverse extragenital manifestations of infection both in adult and pediatric populations. The clinical presentation of extrag...

journal_title：Current infectious disease reports

authors： Spencer SE,Bash MC

更新日期：2006-03-01 00:00:00

abstract：:Ventilator-associated pneumonia (VAP), an infection of the lower respiratory tract which occurs in association with mechanical ventilation, is one of the most common causes of nosocomial infection in the intensive care unit (ICU). VAP causes significant morbidity and mortality in critically ill patients including incr...

journal_title：Current infectious disease reports

authors： Waters B,Muscedere J

更新日期：2015-08-01 00:00:00

abstract：:Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections have been reported with increasing frequency from many parts of the world. Most infections involve the skin and soft tissue structures, and CA-MRSA is now the most commonly identifiable cause of purulent skin and soft tissue infectio...

journal_title：Current infectious disease reports

authors： Abrahamian FM,Snyder EW

更新日期：2007-09-01 00:00:00

abstract：:Three newer oral antifungal agents, itraconazole, terbinafine and fluconazole, have revolutionized treatment of superficial mycoses. The tissue pharmacokinetics of itraconazole and terbinafine allow much shorter courses of therapy- with higher efficacy-in the treatment of onychomycosis, compared to other oral agents. ...

journal_title：Current infectious disease reports

authors： Del Rosso JQ

更新日期：2000-10-01 00:00:00

abstract：:Solid organ and hematopoietic stem cell transplant recipients may be exposed to diseases which may be prevented through live attenuated virus vaccines (LAVV). Because of their immunosuppression, these diseases can lead to severe complications in transplant recipients. Despite increasing evidence regarding the safety a...

journal_title：Current infectious disease reports

authors： Verolet CM,Posfay-Barbe KM

更新日期：2015-04-01 00:00:00

abstract：:Rotaviruses are the most important cause of pediatric gastroenteritis worldwide. In August 1998, a new rotavirus vaccine was licensed for general use in the United States. However, 14 months later, the vaccine was withdrawn from the market because of serious gastrointestinal side effects. This paper discusses the need...

journal_title：Current infectious disease reports

authors： Coffin SE

更新日期：2000-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Community-acquired pneumonia (CAP) is the cause of a considerable burden of morbidity and mortality among HIV-infected patients. The purpose of this study was to review recent literature for epidemiological trends and management of CAP in HIV patients. RECENT FINDINGS:While the specific infectious et...

journal_title：Current infectious disease reports

authors： Almeida A,Boattini M

更新日期：2017-01-01 00:00:00

abstract：:The immune reconstitution inflammatory syndrome (IRIS) is a well-described phenomenon in HIV-infected patients following initiation of antiretroviral therapy and can lead to significant morbidity and mortality in some patients. Risk for IRIS is enhanced in those with low CD4 counts and preexisting opportunistic infect...

journal_title：Current infectious disease reports

authors： Armstrong WS

更新日期：2013-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Modern advances in malaria rapid diagnostic test (RDT) technology have increased demand for low-cost, easy-to-use assays in areas endemic for malaria. Substantial developments in diagnostic sensitivity and specificity, improvements in non-falciparum RDTs, and novel biotechnological innovations are gra...

journal_title：Current infectious disease reports

authors： Mukkala AN,Kwan J,Lau R,Harris D,Kain D,Boggild AK

更新日期：2018-10-23 00:00:00

abstract：:Candida species are an important cause of health care-related bloodstream infections (BSI). Understanding the current Candida BSI incidence trends, the dominant species causing disease, and the mortality associated with this infection are important to help guide therapeutic and prophylaxis measures. In this review, tr...

journal_title：Current infectious disease reports

authors： Morgan J

更新日期：2005-11-01 00:00:00

abstract：:In the United States each year, influenza accounts for an estimated 20,000 to 40,000 deaths, nearly 300,000 hospitalizations, and millions of days lost from work. In the past few years, there has been an explosion of information in the medical literature related to influenza. This paper reviews these latest developmen...

journal_title：Current infectious disease reports

authors： Neuzil KM

更新日期：2000-06-01 00:00:00

abstract：:Arthroplasty of the knee and hip is a common procedure. There is a risk of infection with primary arthroplasty, with an incidence of 1% to 2%. Significant cost and morbidity are associated with infection of the prosthetic joint. Most infections (60% to 70%) are caused by staphylococci, but approximately 10% are caused...

journal_title：Current infectious disease reports

authors： Lentino JR

更新日期：2004-10-01 00:00:00

abstract：:The ability to predict efficacy and toxicity during antiretroviral therapy for HIV would be of obvious advantage. The substantial variability between patients in terms of bioavailability and distribution of current regimens is likely driven by genetic and environmental factors. Protease inhibitors and nucleoside/nucle...

journal_title：Current infectious disease reports

authors： Owen A

更新日期：2006-09-01 00:00:00

abstract：:High-risk human papillomaviruses (HPVs) are now recognized as the etiologic agents of invasive cervical cancer, a major cancer in women. A single HPV type (type 16) is responsible for about 50% of the cancers. The major capsid protein of papillomaviruses, L1, when expressed by recombinant DNA technology, has the intri...

journal_title：Current infectious disease reports

authors： Gravitt PE,Shah KV

更新日期：2005-03-01 00:00:00

abstract：:Although waterborne pathogens are relatively uncommon causes of cutaneous infections, these agents are being recognized with increasing frequency. Humans are exposed to water through a variety of recreational and occupational activities. Poor sanitary conditions in developing nations place the human populations at con...

journal_title：Current infectious disease reports

authors： Elko L,Rosenbach K,Sinnott J

更新日期：2003-10-01 00:00:00

abstract：:Community-acquired pneumonia (CAP) is one of the most common causes of morbidity and mortality in elderly and children. Vitamin C is known as a physiological antioxidant, regulating innate immune system in the lung. Vitamin C has been used to prevent and treat CAP. However, the use of vitamin C for preventing and trea...

journal_title：Current infectious disease reports

authors： Li Y,Li G

更新日期：2016-08-01 00:00:00

abstract：:Starting from 2010, the 13-valent pneumococcal conjugate vaccine (PCV13) was introduced in several countries. This paper discusses some of the problems recently emerged after PCV13 use and their clinical impact. The impact of PCV13 has been relevant and has saved millions of children and adults by severe infectious di...

journal_title：Current infectious disease reports

authors： Principi N,Di Cara G,Bizzarri I,Isidori C,Borgia P,Mignini C,Saponara M,Argentiero A,Esposito S

更新日期：2018-01-24 00:00:00

abstract：:Necrotizing enterocolitis (NEC) continues to be a major cause of morbidity and mortality in premature infants. Although the pathogenesis of NEC remains unclear, abnormal bacterial colonization has been postulated as playing a central role. Various factors impact bacterial colonization following delivery. Compared to t...

journal_title：Current infectious disease reports

authors： Stenger MR,Reber KM,Giannone PJ,Nankervis CA

更新日期：2011-02-01 00:00:00

abstract：:Lower respiratory tract infections (LRTIs) are a global burden to public health and are frequently caused by respiratory viruses. Advances in molecular diagnostic techniques have allowed the identification of previously undetected viral pathogens and have improved our understanding of respiratory virus infections. Her...

journal_title：Current infectious disease reports

authors： Ren L,Xiang Z,Guo L,Wang J

更新日期：2012-06-01 00:00:00