Viral infections of the lower respiratory tract.

Abstract:

:Lower respiratory tract infections (LRTIs) are a global burden to public health and are frequently caused by respiratory viruses. Advances in molecular diagnostic techniques have allowed the identification of previously undetected viral pathogens and have improved our understanding of respiratory virus infections. Here we review the epidemiological and clinical characteristics of recently identified viruses including human metapneumovirus, human coronaviruses NL63 and HKU1, human rhinovirus C, bocavirus, WU and KI polyomaviruses, and parechovirus. The roles of these viruses in LRTIs in children and adults are discussed.

journal_name

Curr Infect Dis Rep

authors

Ren L,Xiang Z,Guo L,Wang J

doi

10.1007/s11908-012-0258-4

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

284-91

issue

3

eissn

1523-3847

issn

1534-3146

journal_volume

14

pub_type

杂志文章
  • Recurrent Bacterial Vaginosis.

    abstract::Bacterial vaginosis (BV) is a common cause of vaginal discharge in women of childbearing age. In some individuals, it recurs frequently after treatment, frustrating both the patient and the physician. Standard BV treatment--metronidazole or clindamycin, administered either intravaginally or orally--is followed by rela...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-000-0053-5

    authors: Hay P

    更新日期:2000-12-01 00:00:00

  • Biofilm Formations in Pediatric Respiratory Tract Infection Part 2: Mucosal Biofilm Formation by Respiratory Pathogens and Current and Future Therapeutic Strategies to Inhibit Biofilm Formation or Eradicate Established Biofilm.

    abstract:PURPOSE OF REVIEW:The purpose of this review is to discuss the unique pathways of biofilm formation utilized by respiratory pathogens and current and future therapeutic strategies to inhibit biofilm formation or eradicate established biofilm in the context of these pathogens. Both nonselective and selective strategies ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-019-0657-x

    authors: Hamilos DL

    更新日期:2019-03-02 00:00:00

  • Structured Treatment Interruption: Approaches and Risks.

    abstract::Although highly active antiretroviral therapy suppresses HIV replication resulting in extraordinary clinical benefits, toxicity, adherence difficulties, and the monetary cost of medications limit the long-term effectiveness and availability of therapy for many HIV-infected individuals. Strategies to interrupt therapy ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-002-0059-2

    authors: Dybul M

    更新日期:2002-04-01 00:00:00

  • Cutaneous Manifestations of Infections in Solid Organ Transplant Recipients.

    abstract:PURPOSE OF REVIEW:Post-transplant infections present a formidable challenge to the physician due to their varied presentation. Many of these infections begin by inoculation following skin compromise or disseminate to the skin hematogenously, making cutaneous manifestations of infection an important diagnostic clue in t...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-018-0621-1

    authors: Pettit CJ,Mazurek K,Kaffenberger B

    更新日期:2018-05-22 00:00:00

  • Urinary tract infection in women: new pathogenic considerations.

    abstract::Urinary tract infection (UTI) is a common clinical syndrome in women. Most UTIs are caused by Escherichia coli. UTI has become a productive and accessible model system for studying the molecular details of how bacteria interact with mucosal surfaces and the nature of the host response. Important advances in the past y...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-006-0021-9

    authors: Stapleton AE

    更新日期:2006-11-01 00:00:00

  • Urinary Tract Infection in Postmenopausal Women.

    abstract::Urinary tract infection (UTI) is common in postmenopausal women; the estimated incidence ranges from 4% to 15%. The clinical presentation of UTI is somewhat different in postmenopausal older women than it is in younger women: postmenopausal women are less likely to report frequency, dysuria, hematuria, and fever, but ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-999-0043-1

    authors: Foxman B

    更新日期:1999-10-01 00:00:00

  • Anti-inflammatory treatment of chronic rhinosinusitis: a shifting paradigm.

    abstract::Treatment of chronic rhinosinusitis still represents an unmet medical need. Presently, the US Food and Drug Administration has not approved any drugs for the treatment of this common condition. Various inflammatory processes are involved in the pathogenesis of chronic rhinosinusitis. Treatment of infection and surgica...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-007-0031-2

    authors: Hatipo U,Rubinstein I

    更新日期:2007-05-01 00:00:00

  • Changing epidemiology of bacterial meningitis.

    abstract::Immunization against the most common meningeal pathogens is the leading factor associated with decreased incidence of bacterial meningitis in countries where routine vaccination is available. This is most dramatically illustrated by the reduction in the incidence of Haemophilus influenzae type b meningitis. The incide...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-007-0047-7

    authors: Dery MA,Hasbun R

    更新日期:2007-07-01 00:00:00

  • Cyclosporiasis: an update.

    abstract::Cyclosporiasis is a food- and water-borne infection that affects healthy and immunocompromised individuals. Awareness of the disease has increased, and outbreaks continue to be reported among vulnerable hosts and now among local residents in endemic areas. Advances in molecular techniques have improved identification ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-009-0016-4

    authors: Warren CA

    更新日期:2009-03-01 00:00:00

  • Clinical Challenges in an Outbreak of COVID-19 in Wuhan, China: Concerns from Frontiers.

    abstract:Purpose of Review:In December 2019, outbreaks of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected pneumonia patients were discovered in Wuhan City, Hubei Province, China. With the spread of the epidemic, new cases have been found in other regions of China and abroad. This review summarizes the curr...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-020-00738-7

    authors: Wang Y,Wang L,Li X,Gong Z

    更新日期:2020-01-01 00:00:00

  • HIV in Africa: Challenges and Directions for the Next Decade.

    abstract::Africa carries a disproportionate burden of the global HIV endemic, accounting for two thirds of the global 33.3 million people living with HIV. While tremendous advances have been made in addressing the HIV epidemic in Africa, considerable challenges remain. Testing for HIV increased by 86% from 2007 to 2009 but more...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-011-0230-8

    authors: Gilliam BL,Patel D,Talwani R,Temesgen Z

    更新日期:2012-02-01 00:00:00

  • Risk Factors for Drug-Resistant Cap in Immunocompetent Patients.

    abstract:PURPOSE OF REVIEW:The increase in drug-resistant community-acquired pneumonia (CAP) is an important problem all over the world. This article explores the current state of antimicrobial resistance of different bacteria that cause CAP and also assesses risk factors to identify those pathogens. RECENT FINDINGS:In the las...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-017-0565-x

    authors: Arancibia F,Ruiz M

    更新日期:2017-03-01 00:00:00

  • Emerging Issues and Treatment Strategies in Carbapenem-Resistant Enterobacteriaceae (CRE).

    abstract::Carbapenems are the broadest spectrum antimicrobials utilized in the treatment of serious infections since the 1980s. Soon after their introduction, the discovery of carbapenem-resistant Enterobacteriaceae (CRE) was reported in the 1990s. Invasive CRE infections are associated with high mortality and limited treatment...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-016-0548-3

    authors: Bowers DR,Huang V

    更新日期:2016-12-01 00:00:00

  • Infectious Considerations in the Pre-Transplant Evaluation of Cirrhotic Patients Awaiting Orthotopic Liver Transplantation.

    abstract::The incidence of end-stage liver disease (ESLD) is increasing and many of these patients may be considered for orthotopic liver transplantation. As patients with ESLD are at risk of a number of infections, infectious disease physicians should be aware of the management of these infections in order to provide optimal p...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-015-0514-5

    authors: Mah A,Wright A

    更新日期:2016-01-01 00:00:00

  • Management of Increased Intracranial Pressure in Cryptococcal Meningitis.

    abstract::Therapy of cryptococcal meningitis has been focused primarily on optimizing the antifungal regimen to improve the previously high treatment failure rates. Until recently, relatively little attention has been paid to the impact of increased intracranial pressure, which is a frequent problem that complicates management ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-002-0026-y

    authors: Gambarin KJ,Hamill RJ

    更新日期:2002-08-01 00:00:00

  • The prospect of vaccination against group A beta-hemolytic streptococci.

    abstract::Group A streptococcus is a widespread human pathogen that causes a broad spectrum of human disease. The persistent high burden and severity of illness in developing and industrialized countries speaks to the need for a safe and effective vaccine. Modern approaches to vaccine construction include M protein type-specifi...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-008-0032-9

    authors: Kotloff KL

    更新日期:2008-05-01 00:00:00

  • Current Management of Onychomycosis and Dermatomycoses.

    abstract::Three newer oral antifungal agents, itraconazole, terbinafine and fluconazole, have revolutionized treatment of superficial mycoses. The tissue pharmacokinetics of itraconazole and terbinafine allow much shorter courses of therapy- with higher efficacy-in the treatment of onychomycosis, compared to other oral agents. ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-000-0074-0

    authors: Del Rosso JQ

    更新日期:2000-10-01 00:00:00

  • Infections of the Central Nervous System in Returning Travelers and Immigrants.

    abstract:PURPOSE OF REVIEW:This review highlights current knowledge in travel-related neuroinfectious diseases, providing insight on approaches to prevention, diagnosis, and treatment of infections of the central nervous system (CNS) in travelers and immigrants. RECENT FINDINGS:Updates on travel vaccine recommendations includi...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-017-0594-5

    authors: Thompson H,Thakur K

    更新日期:2017-10-03 00:00:00

  • The current state and future prospects of chronic hepatitis C virus infection treatment.

    abstract::Hepatitis C virus (HCV) infection is a significant cause of chronic liver disease with substantial long-term sequelae. Until very recently, therapies to cure HCV were hindered by high nonresponse rates and severe side effects. The first-generation protease inhibitor-containing regimens provided superior cure rates for...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-014-0413-1

    authors: Moore C,Levitsky J

    更新日期:2014-08-01 00:00:00

  • Adjunctive Corticosteroids in Adults with Bacterial Meningitis.

    abstract::Bacterial meningitis is a complex disorder in which neurologic injury is caused, in part, by the causative organism and, in part, by the host's own inflammatory response. In studies of experimental bacterial meningitis, adjuvant treatment with corticosteroids, specifically dexamethasone, has beneficial effects. On the...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-005-0061-6

    authors: van de Beek D,de Gans J

    更新日期:2005-07-01 00:00:00

  • Will New Human Papillomavirus Diagnostics Improve Cervical Cancer Control Efforts?

    abstract::With the causal link between specific types of human papillomavirus (HPV) and cervical cancer firmly established, efforts have turned to assessing the relative merits of offering HPV testing in screening, triage, and posttreatment management. Many unanswered questions remain, but a growing body of evidence supports a ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-996-0054-0

    authors: Kulasingam SL,Koutsky LA

    更新日期:2001-04-01 00:00:00

  • Community-associated methicillin-resistant Staphylococcus aureus: incidence, clinical presentation, and treatment decisions.

    abstract::Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections have been reported with increasing frequency from many parts of the world. Most infections involve the skin and soft tissue structures, and CA-MRSA is now the most commonly identifiable cause of purulent skin and soft tissue infectio...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-007-0061-9

    authors: Abrahamian FM,Snyder EW

    更新日期:2007-09-01 00:00:00

  • Antipsychotic drug use and community-acquired pneumonia.

    abstract::Antipsychotics are generally distinguished as atypical and typical agents, which are indicated in the treatment of acute and chronic psychoses and other psychiatric disorders. In April 2005, the US Food and Drug Administration issued a warning about the increased risk of all-cause mortality associated with atypical an...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-011-0175-y

    authors: Trifirò G

    更新日期:2011-06-01 00:00:00

  • Methicillin-resistant Staphylococcus aureus: from the hospital to the community.

    abstract::Infections due to community-associated methicillin---resistant Staphylococcus aureus (CA-MRSA) are becoming more prevalent. CA-MRSA infections have unique epidemiologic features and virulence factors. Compared with health care-associated MRSA (HA-MRSA), most CA-MRSA is clonal type USA300 or 400 and has the Staphylococ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-008-0005-z

    authors: Paez A,Skiest D

    更新日期:2008-03-01 00:00:00

  • Molecular Diagnostic Advances in Transplant Infectious Diseases.

    abstract:PURPOSE OF REVIEW:The infectious complications of transplantation can have devastating consequences for patients. Early and accurate diagnosis is essential to good outcomes. This review describes recent advances in pathogen-directed diagnostic testing and discusses the role of new methods for transplant infectious dise...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-019-0704-7

    authors: Young BA,Hanson KE,Gomez CA

    更新日期:2019-11-26 00:00:00

  • Genetic analysis of host responses in sepsis.

    abstract::During much of the past century, the microbe itself stood at the heart of microbial pathogenesis. Little thought was devoted to the host per se, though it was granted that differences in susceptibility to certain infections did exist between individuals, and between different ethnic groups. During the past 20 years, e...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-007-1009-9

    authors: Beutler B,Ulevitch RJ

    更新日期:2007-10-01 00:00:00

  • 2009 Pandemic Influenza A (H1N1): Diagnosis, Management, and Prevention- Lessons Learned.

    abstract::The 2009 pandemic influenza A (H1N1) was responsible for the first influenza pandemic of the 21st century. The virus- a previously unknown triple-reassortant virus containing segments of avian, human, and swine origins- generally caused mild disease. Unlike seasonal influenza, 2009 pandemic influenza A (H1N1) primaril...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-010-0157-5

    authors: Swedish KA

    更新日期:2011-04-01 00:00:00

  • Dermatologic Infectious Diseases in International Travelers.

    abstract::Skin lesions provide an important clue to the diagnoses of many infections in returned travelers. New information related to epidemiology, recognition, diagnosis, or management is described for the systemic infections--dengue fever, several of the rickettsial infections, African trypanosomiasis, and coccidioidomycosis...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-004-0025-2

    authors: Wilson ME,Chen LH

    更新日期:2004-02-01 00:00:00

  • The use of tympanocentesis in the diagnosis and management of acute otitis media.

    abstract::Acute otitis media (AOM), when associated with a bulging or full tympanic membrane, has a bacterial etiology in more than 90% of cases. Not infrequently, the organisms present express resistance mechanisms to commonly prescribed antibiotic therapy. Tympanocentesis is a procedure advocated by several national guideline...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-006-0058-9

    authors: Pichichero ME,Wright T

    更新日期:2006-05-01 00:00:00

  • Influenza: New Insights Into an Old Disease.

    abstract::In the United States each year, influenza accounts for an estimated 20,000 to 40,000 deaths, nearly 300,000 hospitalizations, and millions of days lost from work. In the past few years, there has been an explosion of information in the medical literature related to influenza. This paper reviews these latest developmen...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-000-0039-3

    authors: Neuzil KM

    更新日期:2000-06-01 00:00:00