Structured Treatment Interruption: Approaches and Risks.

abstract：:Carbapenems are the broadest spectrum antimicrobials utilized in the treatment of serious infections since the 1980s. Soon after their introduction, the discovery of carbapenem-resistant Enterobacteriaceae (CRE) was reported in the 1990s. Invasive CRE infections are associated with high mortality and limited treatment...

journal_title：Current infectious disease reports

authors： Bowers DR,Huang V

更新日期：2016-12-01 00:00:00

abstract：:A variety of antigen-capture assays are commercially available for the detection of influenza. In addition, real-time multiplex polymerase chain reaction (PCR) has been used to detect influenza A and B in clinical specimens. The commercial assays can be completed in less than 30 minutes and have a sensitivity of at le...

journal_title：Current infectious disease reports

authors： Pachucki CT

更新日期：2005-05-01 00:00:00

abstract：:Rates of syphilis continue to increase in the United States and HIV-infected patients make up a large proportion of cases. The interaction between syphilis and HIV is complex and still incompletely understood. Although diagnosis and management of HIV-infected patients with syphilis is, in general, similar to HIV-uninf...

journal_title：Current infectious disease reports

authors： Ghanem KG

更新日期：2010-03-01 00:00:00

abstract：:Intensive care unit (ICU) patients present several unusual pharmacokinetic (PK) characteristics compared with less seriously ill patients, including increased distribution volume and variable clearance. Interpatient PK variability is often considerable and can produce a wide range of values for PK parameters and major...

journal_title：Current infectious disease reports

authors： Dufour G,Montravers P

更新日期：2009-01-01 00:00:00

abstract：:Invasive fungal infection (IFI) is an important cause of morbidity and mortality in patients with hematologic malignancy, prolonged neutropenia, or after hematopoietic stem cell transplant. Antifungal prophylaxis prevents IFI in high-risk hematology patients. This article discusses recent developments in antifungal pr...

journal_title：Current infectious disease reports

authors： Wolf J,Slavin MA

更新日期：2009-11-01 00:00:00

abstract：:Chikungunya virus (CHIKV) is an alphavirus transmitted by mosquitoes, mostly Aedes aegypti and Aedes albopictus. After half a century of focal outbreaks of acute febrile polyarthralgia in Africa and Asia, the disease unexpectedly spread in the past decade with large outbreaks in Africa and around the Indian Ocean and ...

journal_title：Current infectious disease reports

authors： Simon F,Javelle E,Oliver M,Leparc-Goffart I,Marimoutou C

更新日期：2011-06-01 00:00:00

abstract：:Skin lesions provide an important clue to the diagnoses of many infections in returned travelers. New information related to epidemiology, recognition, diagnosis, or management is described for the systemic infections--dengue fever, several of the rickettsial infections, African trypanosomiasis, and coccidioidomycosis...

journal_title：Current infectious disease reports

authors： Wilson ME,Chen LH

更新日期：2004-02-01 00:00:00

abstract：:Africa carries a disproportionate burden of the global HIV endemic, accounting for two thirds of the global 33.3 million people living with HIV. While tremendous advances have been made in addressing the HIV epidemic in Africa, considerable challenges remain. Testing for HIV increased by 86% from 2007 to 2009 but more...

journal_title：Current infectious disease reports

authors： Gilliam BL,Patel D,Talwani R,Temesgen Z

更新日期：2012-02-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) continues to be a major cause of morbidity and mortality in premature infants. Although the pathogenesis of NEC remains unclear, abnormal bacterial colonization has been postulated as playing a central role. Various factors impact bacterial colonization following delivery. Compared to t...

journal_title：Current infectious disease reports

authors： Stenger MR,Reber KM,Giannone PJ,Nankervis CA

更新日期：2011-02-01 00:00:00

abstract：:Immunization against the most common meningeal pathogens is the leading factor associated with decreased incidence of bacterial meningitis in countries where routine vaccination is available. This is most dramatically illustrated by the reduction in the incidence of Haemophilus influenzae type b meningitis. The incide...

journal_title：Current infectious disease reports

authors： Dery MA,Hasbun R

更新日期：2007-07-01 00:00:00

abstract：:The deadly combination of tuberculosis (TB) and human immunodeficiency virus (HIV) currently ravaging the world, taking a toll of about 0.35 million people every year, is one of the major public health crises of the decade. Throughout the course of HIV infection, the risk of acquisition, reactivation, and reinfection ...

journal_title：Current infectious disease reports

authors： Varghese GM,Janardhanan J,Ralph R,Abraham OC

更新日期：2013-02-01 00:00:00

abstract：:In recent years, substantial advances have been achieved in the treatment of mucormycosis. It is now clear that early initiation of therapy results in substantially better outcomes, underscoring the need to maintain a high index of suspicion and aggressively biopsy potential lesions. Increasing data support the need f...

journal_title：Current infectious disease reports

authors： Spellberg B,Ibrahim AS

更新日期：2010-11-01 00:00:00

abstract：:Clinical toxinology is a specialized area of clinical medicine focused on the pathophysiology, diagnosis, treatment, and prevention of diseases caused by animal, plant, and fungal toxins. This review focuses on recent developments in snakebite. Snakebite is newly recognized as a Neglected Tropical Disease by the World...

journal_title：Current infectious disease reports

authors： White J

更新日期：2011-06-01 00:00:00

abstract：:Although waterborne pathogens are relatively uncommon causes of cutaneous infections, these agents are being recognized with increasing frequency. Humans are exposed to water through a variety of recreational and occupational activities. Poor sanitary conditions in developing nations place the human populations at con...

journal_title：Current infectious disease reports

authors： Elko L,Rosenbach K,Sinnott J

更新日期：2003-10-01 00:00:00

abstract：:Transmissible spongiform encephalopathies (TSEs) are a group of progressive, fatal neurodegenerative disorders that share a common spongiform histopathology. TSEs may be transmitted in a sporadic, familial, iatrogenic, or zoonotic fashion. The putative infectious agent of TSE, the prion, represents a novel paradigm of...

journal_title：Current infectious disease reports

authors： Janka J,Maldarelli F

更新日期：2004-08-01 00:00:00

abstract：:Ventilator-associated pneumonia (VAP), an infection of the lower respiratory tract which occurs in association with mechanical ventilation, is one of the most common causes of nosocomial infection in the intensive care unit (ICU). VAP causes significant morbidity and mortality in critically ill patients including incr...

journal_title：Current infectious disease reports

authors： Waters B,Muscedere J

更新日期：2015-08-01 00:00:00

abstract：:Candida species are an important cause of health care-related bloodstream infections (BSI). Understanding the current Candida BSI incidence trends, the dominant species causing disease, and the mortality associated with this infection are important to help guide therapeutic and prophylaxis measures. In this review, tr...

journal_title：Current infectious disease reports

authors： Morgan J

更新日期：2005-11-01 00:00:00

abstract：:Bacterial meningitis is a complex disorder in which neurologic injury is caused, in part, by the causative organism and, in part, by the host's own inflammatory response. In studies of experimental bacterial meningitis, adjuvant treatment with corticosteroids, specifically dexamethasone, has beneficial effects. On the...

journal_title：Current infectious disease reports

authors： van de Beek D,de Gans J

更新日期：2005-07-01 00:00:00

abstract：:Candida species remain the most frequently isolated fungi in intensive care unit (ICU) patients with severe sepsis or septic shock. Delayed antifungal therapy in these patients is a recognized risk factor for mortality. However, the diagnosis of invasive candidiasis remains difficult and is frequently delayed. Clinica...

journal_title：Current infectious disease reports

authors： Allou N,Allyn J,Montravers P

更新日期：2011-10-01 00:00:00

abstract：:Myocarditis is an acquired form inflammatory heart muscle disease, manifested as acute and chronic conditions. While many etiologies have been reported, the most common cause of this disease is infection, primarily viral. Typically, the specific causative agent(s) and mechanism(s) are elusive. Over the past several ye...

journal_title：Current infectious disease reports

authors： Bowles NE,Towbin JA

更新日期：2000-08-01 00:00:00

abstract：:During much of the past century, the microbe itself stood at the heart of microbial pathogenesis. Little thought was devoted to the host per se, though it was granted that differences in susceptibility to certain infections did exist between individuals, and between different ethnic groups. During the past 20 years, e...

journal_title：Current infectious disease reports

authors： Beutler B,Ulevitch RJ

更新日期：2007-10-01 00:00:00

abstract：:Community-acquired pneumonia is a common reason for hospitalization and leads to significant morbidity and mortality. There are published evidence-based guidelines for the diagnosis, treatment, and management of community-acquired pneumonia. Many countries, including the US, have developed national, publically reporte...

journal_title：Current infectious disease reports

authors： Richey EA,Dudley L,Liu SK

更新日期：2014-02-01 00:00:00

abstract：:Arthroplasty of the knee and hip is a common procedure. There is a risk of infection with primary arthroplasty, with an incidence of 1% to 2%. Significant cost and morbidity are associated with infection of the prosthetic joint. Most infections (60% to 70%) are caused by staphylococci, but approximately 10% are caused...

journal_title：Current infectious disease reports

authors： Lentino JR

更新日期：2004-10-01 00:00:00

abstract：:The outcome for HIV-infected patients with cancer has dramatically improved in the highly active antiretroviral therapy (HAART) era, probably due to improvements in immune status and bone marrow function that allow the possibility of increased drug-dose intensity with a higher complete remission rate. Although data re...

journal_title：Current infectious disease reports

authors： Rosso R,Di Biagio A,Viscoli C

更新日期：2008-05-01 00:00:00

abstract：:Hepatitis delta virus (HDV) is a unique human virus, showing similarities with plant viroids. Although impressive knowledge on virus structure and replication has been achieved, several questions like HBV/HDV interaction and post translational modifications of HD antigens remain to be answered. Potential targets for t...

journal_title：Current infectious disease reports

authors： Niro GA,Smedile A

更新日期：2012-02-01 00:00:00

abstract：:Reduction of microbial contamination of the hospital environment is a challenge, yet has potential impacts on infection prevention efforts. Fumigation and UV light devices for environmental cleaning have expanded into the health care setting with the goal of decontamination of difficult to clean or overlooked surfaces...

journal_title：Current infectious disease reports

authors： Doll M,Morgan DJ,Anderson D,Bearman G

更新日期：2015-09-01 00:00:00

abstract：:Increases in sexually transmitted diseases (STDs) among men who have sex with men (MSM) have coincided with recent increases in sexual risk behaviors across the United States and Europe. The identification of same-sex sexual risk behavior in men and the subsequent risk for certain bacterial and viral infections requir...

journal_title：Current infectious disease reports

authors： Klausner JD,Wong W

更新日期：2003-04-01 00:00:00

abstract：:The dogma is that the higher risk of pyelonephritis in pregnant women is explained entirely by anatomic/obstructive changes. If so, gestational pyelonephritis should be caused by random, nonpathogenic bacteria. Instead, gestational pyelonephritis is associated with a narrow group of genetically related Escherichia col...

journal_title：Current infectious disease reports

authors： Nowicki B

更新日期：2002-12-01 00:00:00

abstract：:A broad range of disorders can cause inflammation of the thyroid gland. True thyroid infections are rare and can result from a variety of microorganisms, of which bacteria are the most common. Other rarer pathogens include fungi, parasites, and viruses. Gram-positive bacteria, especially staphylococci, predominate as ...

journal_title：Current infectious disease reports

authors： Shah SS,Baum SG

更新日期：2000-04-01 00:00:00

abstract：:It is well established that the immunological response to the seasonal trivalent influenza vaccine is attenuated in cancer patients. Furthermore, rates of seroprotection and seroconversion vary by malignancy type and are higher in patients with solid tumors, as compared either with those with hematologic malignancies ...

journal_title：Current infectious disease reports

authors： Baluch A,Pasikhova Y

更新日期：2013-12-01 00:00:00