Molecular Aspects of Myocarditis.

Abstract:

:Myocarditis is an acquired form inflammatory heart muscle disease, manifested as acute and chronic conditions. While many etiologies have been reported, the most common cause of this disease is infection, primarily viral. Typically, the specific causative agent(s) and mechanism(s) are elusive. Over the past several years, various new findings have added to our understanding of myocarditis. These include the identification of adenoviruses as important causative agents, a new receptor protein likely to play an important role in the virulence of certain agents affecting the myocardium, and the effect of viruses on the cardiac cytoskeleton. This report reviews the current understanding of myocarditis, proposes a hypothesis about the long-term sequelae, and suggests possible new therapeutic strategies.

journal_name

Curr Infect Dis Rep

authors

Bowles NE,Towbin JA

doi

10.1007/s11908-000-0008-x

keywords:

subject

Has Abstract

pub_date

2000-08-01 00:00:00

pages

308-314

issue

4

eissn

1523-3847

issn

1534-3146

journal_volume

2

pub_type

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