Diagnosis and Management of Infectious Thyroiditis.

abstract：:Treatment of chronic rhinosinusitis still represents an unmet medical need. Presently, the US Food and Drug Administration has not approved any drugs for the treatment of this common condition. Various inflammatory processes are involved in the pathogenesis of chronic rhinosinusitis. Treatment of infection and surgica...

journal_title：Current infectious disease reports

authors： Hatipo U,Rubinstein I

更新日期：2007-05-01 00:00:00

abstract：PURPOSE OF REVIEW:Suppressive therapy and periodic presumptive treatment (PPT) are distinct but related strategies that have been used to reduce the incidence of bacterial vaginosis (BV). Here, we review clinical trial evidence of the effectiveness of suppressive therapy and PPT to reduce BV, and discuss their roles fo...

journal_title：Current infectious disease reports

authors： Balkus JE,Carter KA,McClelland RS

更新日期：2019-08-31 00:00:00

abstract：:Antiretroviral therapy (ART) does not eliminate HIV-1 from latently infected reservoirs, and this remains the critical obstacle to the eradication of infection. Although ART is effective in suppressing viral load, life-long ART is burdensome in many respects. Given expanding numbers of HIV-infected individuals on ART ...

journal_title：Current infectious disease reports

authors： Margolis DM

更新日期：2014-03-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to review therapies with new mechanisms of action for the treatment of HIV that are at least in phase 2 clinical trials. RECENT FINDINGS:There are several new mechanisms of action being represented within clinical development, including histone deacetylase (HDAC) inhibito...

journal_title：Current infectious disease reports

authors： Gravatt LAH,Leibrand CR,Patel S,McRae M

更新日期：2017-09-19 00:00:00

abstract：:Oral triazole therapy is well established for the treatment of invasive aspergillosis (IPA), allergic aspergillosis (ABPA), and chronic pulmonary aspergillosis (CPA), and is often long-term. Resistance to triazole azole antifungal drugs in Aspergillus fumigatus is now a major clinical problem in a number of European l...

journal_title：Current infectious disease reports

authors： Bowyer P,Moore CB,Rautemaa R,Denning DW,Richardson MD

更新日期：2011-12-01 00:00:00

abstract：:The immune reconstitution inflammatory syndrome (IRIS) is a well-described phenomenon in HIV-infected patients following initiation of antiretroviral therapy and can lead to significant morbidity and mortality in some patients. Risk for IRIS is enhanced in those with low CD4 counts and preexisting opportunistic infect...

journal_title：Current infectious disease reports

authors： Armstrong WS

更新日期：2013-02-01 00:00:00

abstract：:Although waterborne pathogens are relatively uncommon causes of cutaneous infections, these agents are being recognized with increasing frequency. Humans are exposed to water through a variety of recreational and occupational activities. Poor sanitary conditions in developing nations place the human populations at con...

journal_title：Current infectious disease reports

authors： Elko L,Rosenbach K,Sinnott J

更新日期：2003-10-01 00:00:00

abstract：:A variety of antigen-capture assays are commercially available for the detection of influenza. In addition, real-time multiplex polymerase chain reaction (PCR) has been used to detect influenza A and B in clinical specimens. The commercial assays can be completed in less than 30 minutes and have a sensitivity of at le...

journal_title：Current infectious disease reports

authors： Pachucki CT

更新日期：2005-05-01 00:00:00

abstract：:The 2009 pandemic influenza A (H1N1) was responsible for the first influenza pandemic of the 21st century. The virus- a previously unknown triple-reassortant virus containing segments of avian, human, and swine origins- generally caused mild disease. Unlike seasonal influenza, 2009 pandemic influenza A (H1N1) primaril...

journal_title：Current infectious disease reports

authors： Swedish KA

更新日期：2011-04-01 00:00:00

abstract：:Ventilator-associated pneumonia (VAP), an infection of the lower respiratory tract which occurs in association with mechanical ventilation, is one of the most common causes of nosocomial infection in the intensive care unit (ICU). VAP causes significant morbidity and mortality in critically ill patients including incr...

journal_title：Current infectious disease reports

authors： Waters B,Muscedere J

更新日期：2015-08-01 00:00:00

abstract：:Group A streptococcus is a widespread human pathogen that causes a broad spectrum of human disease. The persistent high burden and severity of illness in developing and industrialized countries speaks to the need for a safe and effective vaccine. Modern approaches to vaccine construction include M protein type-specifi...

journal_title：Current infectious disease reports

authors： Kotloff KL

更新日期：2008-05-01 00:00:00

abstract：:Hepatitis delta virus (HDV) is a unique human virus, showing similarities with plant viroids. Although impressive knowledge on virus structure and replication has been achieved, several questions like HBV/HDV interaction and post translational modifications of HD antigens remain to be answered. Potential targets for t...

journal_title：Current infectious disease reports

authors： Niro GA,Smedile A

更新日期：2012-02-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a significant cause of chronic liver disease with substantial long-term sequelae. Until very recently, therapies to cure HCV were hindered by high nonresponse rates and severe side effects. The first-generation protease inhibitor-containing regimens provided superior cure rates for...

journal_title：Current infectious disease reports

authors： Moore C,Levitsky J

更新日期：2014-08-01 00:00:00

abstract：:Neuroimaging studies have revealed that neurocysticercosis is a major cause of neurologic disease in most developing countries and is an emerging disease in industrialized areas. Patients with neurocysticercosis present mainly with seizures (parenchymal form) or intracranial hypertension (ventricular/subarachnoid form...

journal_title：Current infectious disease reports

authors： White AC,Garcia HH

更新日期：1999-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system most often characterized by clinical relapses and periods of remission. RECENT FINDINGS:The past decade has seen a dramatic increase in disease-modifying therapies for MS. Fourteen FDA-approved immunomodulato...

journal_title：Current infectious disease reports

authors： Levin SN,Kaplan TB

更新日期：2017-02-01 00:00:00

abstract：:Although most cases of rhinosinusitis are benign, the disruption of quality of life due to disease symptoms leads patients to seek early medical care. Ongoing debates dispute the definition, bacteriology, and medical management of chronic sinusitis, while the criteria for acute sinusitis are relatively well establishe...

journal_title：Current infectious disease reports

authors： Hadley JA

更新日期：2001-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The infectious complications of transplantation can have devastating consequences for patients. Early and accurate diagnosis is essential to good outcomes. This review describes recent advances in pathogen-directed diagnostic testing and discusses the role of new methods for transplant infectious dise...

journal_title：Current infectious disease reports

authors： Young BA,Hanson KE,Gomez CA

更新日期：2019-11-26 00:00:00

abstract：:Streptococcus bovis is a rare, but important cause of bacterial meningitis in children. Since its discovery in the early 1970s, the pathogen has undergone multiple taxonomic changes producing four distinct subspecies today, the most prevalent of which is S. gallolyticus subsp pasteurianus in infants and children. Whil...

journal_title：Current infectious disease reports

authors： Hede SV

更新日期：2016-03-01 00:00:00

abstract：:Antipsychotics are generally distinguished as atypical and typical agents, which are indicated in the treatment of acute and chronic psychoses and other psychiatric disorders. In April 2005, the US Food and Drug Administration issued a warning about the increased risk of all-cause mortality associated with atypical an...

journal_title：Current infectious disease reports

authors： Trifirò G

更新日期：2011-06-01 00:00:00

abstract：:It is well established that the immunological response to the seasonal trivalent influenza vaccine is attenuated in cancer patients. Furthermore, rates of seroprotection and seroconversion vary by malignancy type and are higher in patients with solid tumors, as compared either with those with hematologic malignancies ...

journal_title：Current infectious disease reports

authors： Baluch A,Pasikhova Y

更新日期：2013-12-01 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights current knowledge in travel-related neuroinfectious diseases, providing insight on approaches to prevention, diagnosis, and treatment of infections of the central nervous system (CNS) in travelers and immigrants. RECENT FINDINGS:Updates on travel vaccine recommendations includi...

journal_title：Current infectious disease reports

authors： Thompson H,Thakur K

更新日期：2017-10-03 00:00:00

abstract：:Although mixed infections are known to be clinically relevant in conditions such as nosocomial pneumonia and ventilator-related pneumonia, it is increasingly recognized that a substantial number of community-acquired lower respiratory tract infections may also be attributed to more than one pathogenic organism. A bett...

journal_title：Current infectious disease reports

authors： Tarsia P,Aliberti S,Pappalettera M,Blasi F

更新日期：2007-01-01 00:00:00

abstract：:Candida species remain the most frequently isolated fungi in intensive care unit (ICU) patients with severe sepsis or septic shock. Delayed antifungal therapy in these patients is a recognized risk factor for mortality. However, the diagnosis of invasive candidiasis remains difficult and is frequently delayed. Clinica...

journal_title：Current infectious disease reports

authors： Allou N,Allyn J,Montravers P

更新日期：2011-10-01 00:00:00

abstract：:All of the endemic mycoses have cutaneous and mucocutaneous manifestations that are most commonly seen when patients have disseminated infection. Biopsy of skin lesions is simple and safe and can assist in making a timely diagnosis of disseminated infection. Primary cutaneous inoculation infection has been reported wi...

journal_title：Current infectious disease reports

authors： Smith JA,Riddell J 4th,Kauffman CA

更新日期：2013-10-01 00:00:00

abstract：:Rates of syphilis continue to increase in the United States and HIV-infected patients make up a large proportion of cases. The interaction between syphilis and HIV is complex and still incompletely understood. Although diagnosis and management of HIV-infected patients with syphilis is, in general, similar to HIV-uninf...

journal_title：Current infectious disease reports

authors： Ghanem KG

更新日期：2010-03-01 00:00:00

abstract：:Fungal endocarditis (FE) is an increasingly prevalent and devastating disease in today's highly advancing medical practice. With more patients receiving broad-spectrum antibiotics or invasive interventions including long-term central venous catheters or prosthetic heart valve placements, FE is increasingly reported. R...

journal_title：Current infectious disease reports

authors： Varghese GM,Sobel JD

更新日期：2008-07-01 00:00:00

abstract：:The pathogenesis of vulvovaginal candidiasis, which is caused by Candida albicans, is poorly understood. Despite a strong protective role for cell-mediated immunity (CMI) against other mucosal candidal infections, numerous studies in humans and most animal models have revealed little to no role for CMI or other forms ...

journal_title：Current infectious disease reports

authors： Fidel PL

更新日期：2003-12-01 00:00:00

abstract：:Starting from 2010, the 13-valent pneumococcal conjugate vaccine (PCV13) was introduced in several countries. This paper discusses some of the problems recently emerged after PCV13 use and their clinical impact. The impact of PCV13 has been relevant and has saved millions of children and adults by severe infectious di...

journal_title：Current infectious disease reports

authors： Principi N,Di Cara G,Bizzarri I,Isidori C,Borgia P,Mignini C,Saponara M,Argentiero A,Esposito S

更新日期：2018-01-24 00:00:00

abstract：:Before the advent of antiretroviral therapy (ART), CMV retinitis was a common, debilitating opportunistic infection in the HIV-infected population. ART has had such a favorable impact on the prevention and management of CMV retinitis that it can be considered in some ways to be CMV therapy. Currently available CMV dir...

journal_title：Current infectious disease reports

authors： Barrett L,Walmsley S

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Modern advances in malaria rapid diagnostic test (RDT) technology have increased demand for low-cost, easy-to-use assays in areas endemic for malaria. Substantial developments in diagnostic sensitivity and specificity, improvements in non-falciparum RDTs, and novel biotechnological innovations are gra...

journal_title：Current infectious disease reports

authors： Mukkala AN,Kwan J,Lau R,Harris D,Kain D,Boggild AK

更新日期：2018-10-23 00:00:00