Abstract：
:Although mixed infections are known to be clinically relevant in conditions such as nosocomial pneumonia and ventilator-related pneumonia, it is increasingly recognized that a substantial number of community-acquired lower respiratory tract infections may also be attributed to more than one pathogenic organism. A better definition of the true incidence of mixed infections in community-acquired lower respiratory tract infections is partly derived from recent advances in available diagnostic methods (eg, molecular biology). Two points still must be determined: whether the presence of a mixed infection is associated with altered outcomes and whether empirical antibiotic selection should be modified to account for potential polymicrobial infections.
journal_name
Curr Infect Dis Repjournal_title
Current infectious disease reportsauthors
Tarsia P,Aliberti S,Pappalettera M,Blasi Fdoi
10.1007/s11908-007-0017-0subject
Has Abstractpub_date
2007-01-01 00:00:00pages
14-20issue
1eissn
1523-3847issn
1534-3146journal_volume
9pub_type
杂志文章abstract：:Hepatitis delta virus (HDV) is a unique human virus, showing similarities with plant viroids. Although impressive knowledge on virus structure and replication has been achieved, several questions like HBV/HDV interaction and post translational modifications of HD antigens remain to be answered. Potential targets for t...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-011-0233-5
更新日期：2012-02-01 00:00:00
abstract：:Pulmonary nocardiosis is an uncommon but serious infection that is increasingly found in immunosuppressed persons, especially transplant recipients and persons with AIDS. The Nocardia species are denizens of soil and decaying plants that gain entry to humans through inhalation or inoculation. Pulmonary nocardiosis typ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-001-0032-5
更新日期：2001-06-01 00:00:00
abstract：:The first description of acute respiratory distress syndrome (ARDS) in adults appeared in 1967 and was characterized by dyspnea, hypoxemia, diffuse alveolar infiltrates, and reduced respiratory system compliance. ARDS and acute lung injury (ALI) syndrome have no specific treatment, only supportive care: treating the u...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-009-0052-0
更新日期：2009-09-01 00:00:00
abstract：:Antipsychotics are generally distinguished as atypical and typical agents, which are indicated in the treatment of acute and chronic psychoses and other psychiatric disorders. In April 2005, the US Food and Drug Administration issued a warning about the increased risk of all-cause mortality associated with atypical an...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-011-0175-y
更新日期：2011-06-01 00:00:00
abstract：:Drotrecogin alfa (activated) (DrotAA) has been approved for therapy of severe sepsis and septic shock for 7 years, but controversy persists regarding efficacy and safety. Only a single randomized, controlled trial (Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis; PROWESS) has shown evidence...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-008-0060-5
更新日期：2008-09-01 00:00:00
abstract：:Determining the microbiologic etiology of enteric infection remains an elusive goal. Conventional approaches, including culture, microscopy, and antigen-based tests have significant limitations such as limit of detection and the need for multiple procedures. Molecular diagnostics, especially PCR based tests, are rapid...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-011-0223-7
更新日期：2012-02-01 00:00:00
abstract：:Necrotizing enterocolitis (NEC) continues to be a major cause of morbidity and mortality in premature infants. Although the pathogenesis of NEC remains unclear, abnormal bacterial colonization has been postulated as playing a central role. Various factors impact bacterial colonization following delivery. Compared to t...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-010-0156-6
更新日期：2011-02-01 00:00:00
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journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-007-0031-2
更新日期：2007-05-01 00:00:00
abstract：:Hepatic failure due to hepatitis C is the leading indicator for orthotopic liver transplantation (OLT) in the United States. Unfortunately, recurrent hepatitis C virus infection is essentially universal following orthotopic liver transplantation. Although significant advances have been made in the past decade for the ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-002-0049-4
更新日期：2002-04-01 00:00:00
abstract：:Healthcare-associated bacterial meningitis may occur after neurosurgical procedures, head trauma, and following placement of external or internal ventricular catheters. The likely microorganisms that cause meningitis in this setting (ie, staphylococci and gram-negative bacilli) are different from those that cause meni...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-011-0190-z
更新日期：2011-08-01 00:00:00
abstract：:The deadly combination of tuberculosis (TB) and human immunodeficiency virus (HIV) currently ravaging the world, taking a toll of about 0.35 million people every year, is one of the major public health crises of the decade. Throughout the course of HIV infection, the risk of acquisition, reactivation, and reinfection ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-012-0311-3
更新日期：2013-02-01 00:00:00
abstract：:Clostridium difficile is a major cause of antibiotic-associated diarrhea. While treatment regimens for C. difficile have been available for decades, they remain less than optimal due to the frequent recurrences that occur after therapy is completed. Moreover, the morbidity and expense associated with C. difficile have...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-996-0032-6
更新日期：2001-04-01 00:00:00
abstract：:Heavily pretreated HIV-infected patients with multidrug-resistant virus remain a clinical challenge to the treating physician. While the goal of therapy in such patients is still controversial, sustained immunologic and clinical benefit have only been demonstrated with complete suppression of plasma viral load below d...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-002-0089-9
更新日期：2002-06-01 00:00:00
abstract：:Fungi are common inhabitants of the oral and nasal mucosa, and therefore the differentiation between colonization and pathogenicity in the setting of upper respiratory tract infection symptoms can be difficult. Fungal head and neck infections occur in both immunocompetent and immunocompromised persons, and patients wi...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-002-0078-z
更新日期：2002-06-01 00:00:00
abstract：:Diarrhea is one of the most common health problems among travelers. Although enterotoxigenic Escherichia coli is implicated most commonly, enteroaggregative E. coli has recently been described as a major pathogen. Shigella, Campylobacter, and Salmonella organisms are less common causes of acute diarrhea, and intestina...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-002-0070-7
更新日期：2002-02-01 00:00:00
abstract：:Patients with sepsis may require mechanical ventilation due to the acute respiratory distress syndrome (ARDS). It has become increasingly accepted that mechanical ventilation can contribute to lung injury in these patients. The modern concept of ventilator-induced lung injury is described in the context of alveolar ov...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-005-0007-z
更新日期：2005-09-01 00:00:00
abstract：:Rotaviruses are the most important cause of pediatric gastroenteritis worldwide. In August 1998, a new rotavirus vaccine was licensed for general use in the United States. However, 14 months later, the vaccine was withdrawn from the market because of serious gastrointestinal side effects. This paper discusses the need...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-000-0090-0
更新日期：2000-02-01 00:00:00
abstract：:Dermatologic manifestations of travel-related illness are particularly vexing due to the broad differential diagnosis and clinicians' unfamiliarity with uncommonly seen diseases. This paper aims to educate and update the reader on selected infectious diseases in the returned traveler whose disease manifestations are p...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-015-0467-8
更新日期：2015-03-01 00:00:00
abstract：:All of the endemic mycoses have cutaneous and mucocutaneous manifestations that are most commonly seen when patients have disseminated infection. Biopsy of skin lesions is simple and safe and can assist in making a timely diagnosis of disseminated infection. Primary cutaneous inoculation infection has been reported wi...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-013-0352-2
更新日期：2013-10-01 00:00:00
abstract：:Community-acquired pneumonia (CAP) is one of the most common causes of morbidity and mortality in elderly and children. Vitamin C is known as a physiological antioxidant, regulating innate immune system in the lung. Vitamin C has been used to prevent and treat CAP. However, the use of vitamin C for preventing and trea...
journal_title：Current infectious disease reports
pub_type： 杂志文章,评审
doi：10.1007/s11908-016-0530-0
更新日期：2016-08-01 00:00:00
abstract：:Chlamydia psittaci, Chlamydia pneumoniae, and Mycoplasma pneumoniae are a group of respiratory pathogens that have similar pulmonary and extrapulmonary manifestations. Recent studies suggest that C. pneumoniae and M. pneumoniae may play a role in the pathogenesis of asthma, but further studies are needed to delineate ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-999-0013-7
更新日期：1999-04-01 00:00:00
abstract：:Elderly are at high risk for hospitalization for community-acquired pneumonia (CAP), especially due to Streptococcus pneumoniae, and seasonal influenza viruses. Data suggest PPV23's influence on various CAP-related outcomes among the elderly may depend upon how many years have elapsed since they received this vaccine....
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-015-0505-6
更新日期：2015-12-01 00:00:00
abstract：:Therapy of cryptococcal meningitis has been focused primarily on optimizing the antifungal regimen to improve the previously high treatment failure rates. Until recently, relatively little attention has been paid to the impact of increased intracranial pressure, which is a frequent problem that complicates management ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-002-0026-y
更新日期：2002-08-01 00:00:00
abstract：:Contact precautions are routinely employed for the control of multidrug-resistant organisms. Robust measures, however, for the incremental benefit of contact precautions, gowns, gloves, and active detection and isolation strategies for the prevention of cross-transmission in endemic settings are lacking. Unintended co...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-012-0299-8
更新日期：2012-12-01 00:00:00
abstract：:The pathogenesis of vulvovaginal candidiasis, which is caused by Candida albicans, is poorly understood. Despite a strong protective role for cell-mediated immunity (CMI) against other mucosal candidal infections, numerous studies in humans and most animal models have revealed little to no role for CMI or other forms ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-003-0092-9
更新日期：2003-12-01 00:00:00
abstract：:Africa carries a disproportionate burden of the global HIV endemic, accounting for two thirds of the global 33.3 million people living with HIV. While tremendous advances have been made in addressing the HIV epidemic in Africa, considerable challenges remain. Testing for HIV increased by 86% from 2007 to 2009 but more...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-011-0230-8
更新日期：2012-02-01 00:00:00
abstract：:Prosthetic valve endocarditis (PVE) due to mycobacteria is a rare but frequently fatal complication that may occur early after the surgical procedure, or even years later. Infection has been described with both mechanical and biologic valvular prosthesis. The most commonly implicated mycobacterial species belong to th...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-010-0108-1
更新日期：2010-07-01 00:00:00
abstract：:Ventilator-associated pneumonia (VAP), an infection of the lower respiratory tract which occurs in association with mechanical ventilation, is one of the most common causes of nosocomial infection in the intensive care unit (ICU). VAP causes significant morbidity and mortality in critically ill patients including incr...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-015-0496-3
更新日期：2015-08-01 00:00:00
abstract：:The dogma is that the higher risk of pyelonephritis in pregnant women is explained entirely by anatomic/obstructive changes. If so, gestational pyelonephritis should be caused by random, nonpathogenic bacteria. Instead, gestational pyelonephritis is associated with a narrow group of genetically related Escherichia col...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-002-0041-z
更新日期：2002-12-01 00:00:00
abstract：PURPOSE OF REVIEW:This review aims to determine the effectiveness of the use of syndrome diagnosis in the evaluation of vaginitis and to make suggestions based on the review findings. RECENT FINDINGS:Vaginal discharge as the main symptom of vaginitis is unspecific. A randomized study of symptom-based diagnosis and tre...
journal_title：Current infectious disease reports
pub_type： 杂志文章,评审
doi：10.1007/s11908-017-0558-9
更新日期：2017-01-01 00:00:00
