Update on Traveler's Diarrhea.

Abstract:

:Diarrhea is one of the most common health problems among travelers. Although enterotoxigenic Escherichia coli is implicated most commonly, enteroaggregative E. coli has recently been described as a major pathogen. Shigella, Campylobacter, and Salmonella organisms are less common causes of acute diarrhea, and intestinal protozoa are typical causes of protracted diarrhea. Although education is the mainstay of prevention measures, behavior modification has been shown to be difficult. Chemoprevention is rarely required with the availability of effective treatment, but there has been some interest in the use of vaccines. Maintenance of hydration is most important in children. In addition to bismuth preparations and loperamide, newer agents being developed for symptomatic relief include zaldaride maleate and racecadotril. Fluoroquinolones effectively treat severe traveler's diarrhea, and even a single dose may be sufficient. However, with the emergence of resistance, particularly in Campylobacter infection, other agents are required; interest has focused on azithromycin and rifaximin.

journal_name

Curr Infect Dis Rep

authors

Cheng AC,Thielman NM

doi

10.1007/s11908-002-0070-7

keywords:

subject

Has Abstract

pub_date

2002-02-01 00:00:00

pages

70-77

issue

1

eissn

1523-3847

issn

1534-3146

journal_volume

4

pub_type

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