Prion Diseases: Update on Mad Cow Disease, Variant Creutzfeldt-Jakob Disease, and the Transmissible Spongiform Encephalopathies.

abstract：:Neurocysticercosis, caused by infection with the pork tapeworm Taenia solium, is increasingly recognized as a cause of neurologic disease worldwide. Because the clinical presentation is nonspecific, diagnosis has been difficult. Advances in imaging studies and serodiagnostic techniques are facilitating the diagnosis o...

journal_title：Current infectious disease reports

authors： Yancey LS,Diaz-Marchan PJ,White AC

更新日期：2005-01-01 00:00:00

abstract：:Many data associate low protease inhibitor plasma concentrations with suboptimal virologic responses, whereas relatively few data associate high plasma concentrations with increased likelihood of toxicity. Knowledge of relationships between concentrations and virologic response is important because significant variabi...

journal_title：Current infectious disease reports

authors： Anderson PL,Fletcher CV

更新日期：2001-08-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Community-acquired pneumonia (CAP) is still associated with a large burden and causes significant morbidity and mortality. Besides universal vaccination and antibiotic treatment, statins as adjunctive therapy may also have a beneficial role in the prevention and treatment of CAP. Our goal from thi...

journal_title：Current infectious disease reports

authors： Batais MA,Khan AR,Bin Abdulhak AA

更新日期：2017-08-01 00:00:00

abstract：:Colonization with Staphylococcus aureus is a risk factor for invasive S. aureus infections. Intranasal mupirocin has effectively eradicated S. aureus colonization and appears to prevent S. aureus nosocomial infections in some patient populations. In hospitals and communities where mupirocin use has been widespread, re...

journal_title：Current infectious disease reports

authors： Polgreen PM,Herwaldt LA

更新日期：2004-12-01 00:00:00

abstract：:Infectious myositis is defined as an infection of a skeletal muscle. Infectious myositis is most commonly caused by bacteria; however, a variety of viral, parasitic, and fungal agents may also cause myositis. The pathogenesis of nonbacterial infectious myositis is via direct or hematogenous infection of the musculatur...

journal_title：Current infectious disease reports

authors： Crum-Cianflone NF

更新日期：2010-09-01 00:00:00

abstract：:Cyclosporiasis is a food- and water-borne infection that affects healthy and immunocompromised individuals. Awareness of the disease has increased, and outbreaks continue to be reported among vulnerable hosts and now among local residents in endemic areas. Advances in molecular techniques have improved identification ...

journal_title：Current infectious disease reports

authors： Warren CA

更新日期：2009-03-01 00:00:00

abstract：:Coronary heart disease (CHD) is an inflammatory process that takes decades to develop. In HIV-seronegative persons, high-sensitivity C-reactive protein is a biologic marker of CHD risk. HIV infection induces chronic inflammation, despite adequate suppression of HIV replication with antiretroviral therapy, resulting in...

journal_title：Current infectious disease reports

authors： Fichtenbaum CJ

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to discuss the unique pathways of biofilm formation utilized by respiratory pathogens and current and future therapeutic strategies to inhibit biofilm formation or eradicate established biofilm in the context of these pathogens. Both nonselective and selective strategies ...

journal_title：Current infectious disease reports

authors： Hamilos DL

更新日期：2019-03-02 00:00:00

abstract：Purpose of Review:In December 2019, outbreaks of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected pneumonia patients were discovered in Wuhan City, Hubei Province, China. With the spread of the epidemic, new cases have been found in other regions of China and abroad. This review summarizes the curr...

journal_title：Current infectious disease reports

authors： Wang Y,Wang L,Li X,Gong Z

更新日期：2020-01-01 00:00:00

abstract：:During much of the past century, the microbe itself stood at the heart of microbial pathogenesis. Little thought was devoted to the host per se, though it was granted that differences in susceptibility to certain infections did exist between individuals, and between different ethnic groups. During the past 20 years, e...

journal_title：Current infectious disease reports

authors： Beutler B,Ulevitch RJ

更新日期：2007-10-01 00:00:00

abstract：:Urinary tract infection (UTI) is a common clinical syndrome in women. Most UTIs are caused by Escherichia coli. UTI has become a productive and accessible model system for studying the molecular details of how bacteria interact with mucosal surfaces and the nature of the host response. Important advances in the past y...

journal_title：Current infectious disease reports

authors： Stapleton AE

更新日期：2006-11-01 00:00:00

abstract：:Clinical toxinology is a specialized area of clinical medicine focused on the pathophysiology, diagnosis, treatment, and prevention of diseases caused by animal, plant, and fungal toxins. This review focuses on recent developments in snakebite. Snakebite is newly recognized as a Neglected Tropical Disease by the World...

journal_title：Current infectious disease reports

authors： White J

更新日期：2011-06-01 00:00:00

abstract：:Although mixed infections are known to be clinically relevant in conditions such as nosocomial pneumonia and ventilator-related pneumonia, it is increasingly recognized that a substantial number of community-acquired lower respiratory tract infections may also be attributed to more than one pathogenic organism. A bett...

journal_title：Current infectious disease reports

authors： Tarsia P,Aliberti S,Pappalettera M,Blasi F

更新日期：2007-01-01 00:00:00

abstract：:Chlamydia psittaci, Chlamydia pneumoniae, and Mycoplasma pneumoniae are a group of respiratory pathogens that have similar pulmonary and extrapulmonary manifestations. Recent studies suggest that C. pneumoniae and M. pneumoniae may play a role in the pathogenesis of asthma, but further studies are needed to delineate ...

journal_title：Current infectious disease reports

authors： Atmar RL

更新日期：1999-04-01 00:00:00

abstract：:The possibility that infection with Chlamydia pneumoniae may somehow contribute to the pathogenesis of atherosclerosis continues to be explored by researchers worldwide. A direct cause-and-effect relationship between the bacterium and subsequent development of atherosclerosis has yet to be proved. However, compelling ...

journal_title：Current infectious disease reports

authors： O'Donnell JA

更新日期：1999-06-01 00:00:00

abstract：:Primary infection of humans with varicella zoster virus (VZV) causes varicella (chickenpox), after which the virus becomes latent in cranial nerve ganglia, dorsal root ganglia and autonomic ganglia along the entire neuraxis. As VZV-specific cell-mediated immunity declines in elderly and immunocompromised individuals, ...

journal_title：Current infectious disease reports

authors： Nagel MA,Gilden D

更新日期：2014-06-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Patients with COPD are at increased risk for community-acquired pneumonia (CAP). COPD has been reported as a comorbidity in at least one third of the hospitalized patients with CAP. There is a controversy that the pre...

journal_title：Current infectious disease reports

authors： Cilli A

更新日期：2015-01-01 00:00:00

abstract：:Although waterborne pathogens are relatively uncommon causes of cutaneous infections, these agents are being recognized with increasing frequency. Humans are exposed to water through a variety of recreational and occupational activities. Poor sanitary conditions in developing nations place the human populations at con...

journal_title：Current infectious disease reports

authors： Elko L,Rosenbach K,Sinnott J

更新日期：2003-10-01 00:00:00

abstract：:Vaginal discharge, vulvar pruritus, and dyspareunia are among the most common symptoms that prompt women to seek medical advice. They are frequently assumed to be due to vaginitis resulting from infection and are treated with anti-infective agents without further investigation. Such empirical treatment may be successf...

journal_title：Current infectious disease reports

authors： Dennerstein GJ

更新日期：2008-11-01 00:00:00

abstract：:Drotrecogin alfa (activated) (DrotAA) has been approved for therapy of severe sepsis and septic shock for 7 years, but controversy persists regarding efficacy and safety. Only a single randomized, controlled trial (Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis; PROWESS) has shown evidence...

journal_title：Current infectious disease reports

authors： Barie PS

更新日期：2008-09-01 00:00:00

abstract：:Cervical lymphadenopathy is a common problem in children. The condition most commonly represents a transient response to a benign local or generalized infection. Acute bilateral cervical lymphadenitis is usually caused by a viral upper respiratory tract infection or streptococcal pharyngitis. Acute unilateral cervical...

journal_title：Current infectious disease reports

authors： Leung AK,Davies HD

更新日期：2009-05-01 00:00:00

abstract：:Although modern medicine has improved survival in congenital heart disease dramatically, the long-term course carries a risk of late complications. The incidence of infective endocarditis in adults with congenital heart disease is more than 10 times higher than that of the normal population. Identification of the high...

journal_title：Current infectious disease reports

authors： Thilén U

更新日期：2003-08-01 00:00:00

abstract：:Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and cause a wide range of diseases in humans. Pulmonary involvement, the most common disease manifestation of NTM infection, is being increasingly encountered in clinical settings. In addition, specific phenotypic and genetic characteristics of person...

journal_title：Current infectious disease reports

authors： Saleeb P,Olivier KN

更新日期：2010-05-01 00:00:00

abstract：:Necrotizing enterocolitis (NEC) continues to be a major cause of morbidity and mortality in premature infants. Although the pathogenesis of NEC remains unclear, abnormal bacterial colonization has been postulated as playing a central role. Various factors impact bacterial colonization following delivery. Compared to t...

journal_title：Current infectious disease reports

authors： Stenger MR,Reber KM,Giannone PJ,Nankervis CA

更新日期：2011-02-01 00:00:00

abstract：:Two million of the 15 million (13.3%) new cases of sexually transmitted infections (STIs) among persons 15 to 49 years old occur in pregnant women. Access to care and a provider's ability to assess risk, screen, and treat STIs are critical factors in preventing adverse pregnancy outcomes. Significant variations in pro...

journal_title：Current infectious disease reports

authors： Johnson HL,Erbelding EJ,Ghanem KG

更新日期：2007-03-01 00:00:00

abstract：:The pathogenesis of vulvovaginal candidiasis, which is caused by Candida albicans, is poorly understood. Despite a strong protective role for cell-mediated immunity (CMI) against other mucosal candidal infections, numerous studies in humans and most animal models have revealed little to no role for CMI or other forms ...

journal_title：Current infectious disease reports

authors： Fidel PL

更新日期：2003-12-01 00:00:00

abstract：:In most high-income countries, fewer children now acquire meningitis, and many of those who do will survive. Globally, however, meningitis still remains a significant cause of child morbidity and mortality. In this article, the authors review recent evidence on the morbidity faced by childhood survivors of bacterial m...

journal_title：Current infectious disease reports

authors： Hudson LD,Viner RM,Christie D

更新日期：2013-06-01 00:00:00

abstract：:There is strong evidence that preoperative nasal S. aureus screening/decolonization will significantly reduce surgical site infections (SSIs) after joint prostheses implantation. There is some evidence that antibiotic-containing bone cement may lower SSI rates. Timely administration of perioperative systemic antibioti...

journal_title：Current infectious disease reports

authors： Vonberg RP,Gastmeier P

更新日期：2012-10-01 00:00:00

abstract：:Human herpesvirus 8 (HHV-8) or Kaposi's sarcoma (KS)-associated herpesvirus is a recently identified virus that is associated with KS, multicentric Castleman's disease, and body cavity-based lymphomas. KS is the most common kind of cancer in AIDS patients and the initial AIDS-defining condition in over 20% of patients...

journal_title：Current infectious disease reports

authors： Greenblatt RM

更新日期：1999-08-01 00:00:00

abstract：:In an era of cost-consciousness in the delivery of medical care, the economics of healthcare delivery for HIV-infected persons has been an area of active interest. Interested parties include the payors of HIV care, particularly public insurers, who are paying for an increasing amount of the overall cost of HIV care in...

journal_title：Current infectious disease reports

authors： Moore RD

更新日期：2000-08-01 00:00:00