Abstract:
:Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Patients with COPD are at increased risk for community-acquired pneumonia (CAP). COPD has been reported as a comorbidity in at least one third of the hospitalized patients with CAP. There is a controversy that the presence of concomitant COPD and CAP is associated with a greater risk of death when compared to either condition alone. Risk factors, clinical and immunological characteristics, microbiological etiology, as well as prognosis and treatment of COPD patients with CAP are reviewed in this article.
journal_name
Curr Infect Dis Repjournal_title
Current infectious disease reportsauthors
Cilli Adoi
10.1007/s11908-014-0444-7subject
Has Abstractpub_date
2015-01-01 00:00:00pages
444issue
1eissn
1523-3847issn
1534-3146journal_volume
17pub_type
杂志文章abstract::Pyoderma gangrenosum (PG) is a rare cause of purulent vulvovaginal ulceration. Six recent cases of vulvovaginal pyoderma gangrenosum associated with rituximab are described. All cases were seen in the setting of rituximab used for the treatment of B cell non Hodgkin's lymphoma (NHL). Age range was 50-74; symptoms were...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-015-0478-5
更新日期:2015-05-01 00:00:00
abstract::Neurocysticercosis, caused by infection with the pork tapeworm Taenia solium, is increasingly recognized as a cause of neurologic disease worldwide. Because the clinical presentation is nonspecific, diagnosis has been difficult. Advances in imaging studies and serodiagnostic techniques are facilitating the diagnosis o...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-005-0022-0
更新日期:2005-01-01 00:00:00
abstract::Pouchitis is an inflammatory complication after restorative proctocolectomy and ileal pouch-anal anastomosis (IPAA). IPAA is the surgical treatment of choice in patients with ulcerative colitis (UC) who require colectomy. Initial episodes of acute pouchitis generally respond to antibiotics but significant numbers of c...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-014-0442-9
更新日期:2014-12-01 00:00:00
abstract::Infections due to community-associated methicillin---resistant Staphylococcus aureus (CA-MRSA) are becoming more prevalent. CA-MRSA infections have unique epidemiologic features and virulence factors. Compared with health care-associated MRSA (HA-MRSA), most CA-MRSA is clonal type USA300 or 400 and has the Staphylococ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-008-0005-z
更新日期:2008-03-01 00:00:00
abstract::Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and cause a wide range of diseases in humans. Pulmonary involvement, the most common disease manifestation of NTM infection, is being increasingly encountered in clinical settings. In addition, specific phenotypic and genetic characteristics of person...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0103-6
更新日期:2010-05-01 00:00:00
abstract::The immune reconstitution inflammatory syndrome (IRIS) is a well-described phenomenon in HIV-infected patients following initiation of antiretroviral therapy and can lead to significant morbidity and mortality in some patients. Risk for IRIS is enhanced in those with low CD4 counts and preexisting opportunistic infect...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-012-0308-y
更新日期:2013-02-01 00:00:00
abstract::Immunization against the most common meningeal pathogens is the leading factor associated with decreased incidence of bacterial meningitis in countries where routine vaccination is available. This is most dramatically illustrated by the reduction in the incidence of Haemophilus influenzae type b meningitis. The incide...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-007-0047-7
更新日期:2007-07-01 00:00:00
abstract::Two million of the 15 million (13.3%) new cases of sexually transmitted infections (STIs) among persons 15 to 49 years old occur in pregnant women. Access to care and a provider's ability to assess risk, screen, and treat STIs are critical factors in preventing adverse pregnancy outcomes. Significant variations in pro...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-007-0008-1
更新日期:2007-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Acinetobacter baumannii (AB) is an infamous nosocomial pathogen with a seemingly limitless capacity for antimicrobial resistance, leading to few treatment options and poor clinical outcomes. The debatably low pathogenicity and virulence of AB are juxtaposed by its exceptionally high rate of infection-...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-019-0706-5
更新日期:2019-11-16 00:00:00
abstract::Heavily pretreated HIV-infected patients with multidrug-resistant virus remain a clinical challenge to the treating physician. While the goal of therapy in such patients is still controversial, sustained immunologic and clinical benefit have only been demonstrated with complete suppression of plasma viral load below d...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-002-0089-9
更新日期:2002-06-01 00:00:00
abstract::The dogma is that the higher risk of pyelonephritis in pregnant women is explained entirely by anatomic/obstructive changes. If so, gestational pyelonephritis should be caused by random, nonpathogenic bacteria. Instead, gestational pyelonephritis is associated with a narrow group of genetically related Escherichia col...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-002-0041-z
更新日期:2002-12-01 00:00:00
abstract::Eosinophilia in patients exposed to tropical or subtropical environments is caused most commonly by helminth (worm) infections. Besides a detailed exposure history, the diagnostic approach must consider other infections and noninfectious causes of eosinophilia, as treatments for many of these disorders differ. ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-006-0034-4
更新日期:2006-01-01 00:00:00
abstract::Hepatitis C virus (HCV) infection is a significant cause of chronic liver disease with substantial long-term sequelae. Until very recently, therapies to cure HCV were hindered by high nonresponse rates and severe side effects. The first-generation protease inhibitor-containing regimens provided superior cure rates for...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-014-0413-1
更新日期:2014-08-01 00:00:00
abstract:Purpose of Review:In December 2019, outbreaks of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected pneumonia patients were discovered in Wuhan City, Hubei Province, China. With the spread of the epidemic, new cases have been found in other regions of China and abroad. This review summarizes the curr...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-020-00738-7
更新日期:2020-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to discuss the unique pathways of biofilm formation utilized by respiratory pathogens and current and future therapeutic strategies to inhibit biofilm formation or eradicate established biofilm in the context of these pathogens. Both nonselective and selective strategies ...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-019-0657-x
更新日期:2019-03-02 00:00:00
abstract:PURPOSE OF REVIEW:Modern advances in malaria rapid diagnostic test (RDT) technology have increased demand for low-cost, easy-to-use assays in areas endemic for malaria. Substantial developments in diagnostic sensitivity and specificity, improvements in non-falciparum RDTs, and novel biotechnological innovations are gra...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-018-0655-4
更新日期:2018-10-23 00:00:00
abstract::Noroviruses are among the most common cause of diarrhea in transplant recipients. The clinical spectrum of norovirus infection after transplant is increasingly being recognized. As substantial morbidity is now associated with norovirus infections in this population; the quest for rapid diagnostic modalities and newer ...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-016-0524-y
更新日期:2016-06-01 00:00:00
abstract::High-risk human papillomaviruses (HPVs) are now recognized as the etiologic agents of invasive cervical cancer, a major cancer in women. A single HPV type (type 16) is responsible for about 50% of the cancers. The major capsid protein of papillomaviruses, L1, when expressed by recombinant DNA technology, has the intri...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-005-0072-3
更新日期:2005-03-01 00:00:00
abstract::It is well established that the immunological response to the seasonal trivalent influenza vaccine is attenuated in cancer patients. Furthermore, rates of seroprotection and seroconversion vary by malignancy type and are higher in patients with solid tumors, as compared either with those with hematologic malignancies ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-013-0368-7
更新日期:2013-12-01 00:00:00
abstract::Candida species remain the most frequently isolated fungi in intensive care unit (ICU) patients with severe sepsis or septic shock. Delayed antifungal therapy in these patients is a recognized risk factor for mortality. However, the diagnosis of invasive candidiasis remains difficult and is frequently delayed. Clinica...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-011-0204-x
更新日期:2011-10-01 00:00:00
abstract::Arthroplasty of the knee and hip is a common procedure. There is a risk of infection with primary arthroplasty, with an incidence of 1% to 2%. Significant cost and morbidity are associated with infection of the prosthetic joint. Most infections (60% to 70%) are caused by staphylococci, but approximately 10% are caused...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-004-0038-x
更新日期:2004-10-01 00:00:00
abstract::Primary infection of humans with varicella zoster virus (VZV) causes varicella (chickenpox), after which the virus becomes latent in cranial nerve ganglia, dorsal root ganglia and autonomic ganglia along the entire neuraxis. As VZV-specific cell-mediated immunity declines in elderly and immunocompromised individuals, ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-014-0407-z
更新日期:2014-06-01 00:00:00
abstract::Many data associate low protease inhibitor plasma concentrations with suboptimal virologic responses, whereas relatively few data associate high plasma concentrations with increased likelihood of toxicity. Knowledge of relationships between concentrations and virologic response is important because significant variabi...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-001-0079-3
更新日期:2001-08-01 00:00:00
abstract::Carbapenems are the broadest spectrum antimicrobials utilized in the treatment of serious infections since the 1980s. Soon after their introduction, the discovery of carbapenem-resistant Enterobacteriaceae (CRE) was reported in the 1990s. Invasive CRE infections are associated with high mortality and limited treatment...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-016-0548-3
更新日期:2016-12-01 00:00:00
abstract::Urinary tract infections are common, especially among women, and cause significant morbidity. While prognosis is probably more dependent on whether or not an episode of urinary tract infection is complicated (ie, associated with functional, metabolic, or anatomic abnormalities of the urinary tract) or uncomplicated, a...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-001-0090-8
更新日期:2001-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Post-transplant infections present a formidable challenge to the physician due to their varied presentation. Many of these infections begin by inoculation following skin compromise or disseminate to the skin hematogenously, making cutaneous manifestations of infection an important diagnostic clue in t...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-018-0621-1
更新日期:2018-05-22 00:00:00
abstract::About 1% of all patients with end-stage renal disease in the United States are infected with HIV. With the introduction of highly active antiretroviral therapy (HAART), HIV death rates have declined 80%, and chronic diseases resulting from HIV have replaced opportunistic infections as the leading cause of death among ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-009-0078-3
更新日期:2010-01-01 00:00:00
abstract::Rates of syphilis continue to increase in the United States and HIV-infected patients make up a large proportion of cases. The interaction between syphilis and HIV is complex and still incompletely understood. Although diagnosis and management of HIV-infected patients with syphilis is, in general, similar to HIV-uninf...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0083-6
更新日期:2010-03-01 00:00:00
abstract::Elderly are at high risk for hospitalization for community-acquired pneumonia (CAP), especially due to Streptococcus pneumoniae, and seasonal influenza viruses. Data suggest PPV23's influence on various CAP-related outcomes among the elderly may depend upon how many years have elapsed since they received this vaccine....
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-015-0505-6
更新日期:2015-12-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this article is to perform a systematic review over the past 5 years on the role and effectiveness of clinical decision support systems (CDSSs) on antibiotic stewardship. RECENT FINDINGS:CDDS interventions found a significant impact on multiple outcomes relevant to antibiotic stewardsh...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-019-0683-8
更新日期:2019-07-24 00:00:00