Abstract:
:Pouchitis is an inflammatory complication after restorative proctocolectomy and ileal pouch-anal anastomosis (IPAA). IPAA is the surgical treatment of choice in patients with ulcerative colitis (UC) who require colectomy. Initial episodes of acute pouchitis generally respond to antibiotics but significant numbers of cases eventually become dependent on or refractory to antibiotics. Management of chronic antibiotic refractory pouchitis is challenging and can ultimately lead to pouch failure. The etiopathogenesis is unknown though recent studies have implicated bacterial dysbiosis of the pouch microbiota, NOD2 polymorphism, and Clostridium difficile infection in the development of severe pouchitis. Early identification of risk factors can help in tailoring therapy and reducing cases of chronic pouchitis.
journal_name
Curr Infect Dis Repjournal_title
Current infectious disease reportsauthors
Chowdhry S,Katz JAdoi
10.1007/s11908-014-0442-9subject
Has Abstractpub_date
2014-12-01 00:00:00pages
442issue
12eissn
1523-3847issn
1534-3146journal_volume
16pub_type
杂志文章abstract::Cervical lymphadenopathy is a common problem in children. The condition most commonly represents a transient response to a benign local or generalized infection. Acute bilateral cervical lymphadenitis is usually caused by a viral upper respiratory tract infection or streptococcal pharyngitis. Acute unilateral cervical...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-009-0028-0
更新日期:2009-05-01 00:00:00
abstract::A broad range of disorders can cause inflammation of the thyroid gland. True thyroid infections are rare and can result from a variety of microorganisms, of which bacteria are the most common. Other rarer pathogens include fungi, parasites, and viruses. Gram-positive bacteria, especially staphylococci, predominate as ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-000-0027-7
更新日期:2000-04-01 00:00:00
abstract::Immunization against the most common meningeal pathogens is the leading factor associated with decreased incidence of bacterial meningitis in countries where routine vaccination is available. This is most dramatically illustrated by the reduction in the incidence of Haemophilus influenzae type b meningitis. The incide...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-007-0047-7
更新日期:2007-07-01 00:00:00
abstract::The possibility that infection with Chlamydia pneumoniae may somehow contribute to the pathogenesis of atherosclerosis continues to be explored by researchers worldwide. A direct cause-and-effect relationship between the bacterium and subsequent development of atherosclerosis has yet to be proved. However, compelling ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-996-0021-9
更新日期:1999-06-01 00:00:00
abstract::Fungi are common inhabitants of the oral and nasal mucosa, and therefore the differentiation between colonization and pathogenicity in the setting of upper respiratory tract infection symptoms can be difficult. Fungal head and neck infections occur in both immunocompetent and immunocompromised persons, and patients wi...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-002-0078-z
更新日期:2002-06-01 00:00:00
abstract::In the United States each year, influenza accounts for an estimated 20,000 to 40,000 deaths, nearly 300,000 hospitalizations, and millions of days lost from work. In the past few years, there has been an explosion of information in the medical literature related to influenza. This paper reviews these latest developmen...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-000-0039-3
更新日期:2000-06-01 00:00:00
abstract::This article reviews techniques of rapid testing and the effective diagnosis of streptococcal pharyngitis. Despite 50 years' study of streptococcal pharyngitis and 20 years' experience with rapid tests for its diagnosis, the subject continues to evolve. Rapid diagnostic tests have become more sensitive. Experts now co...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-004-0006-5
更新日期:2004-06-01 00:00:00
abstract::Invasive fungal infection (IFI) is an important cause of morbidity and mortality in patients with hematologic malignancy, prolonged neutropenia, or after hematopoietic stem cell transplant. Antifungal prophylaxis prevents IFI in high-risk hematology patients. This article discusses recent developments in antifungal pr...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-009-0061-z
更新日期:2009-11-01 00:00:00
abstract::Bacterial meningitis remains a feared diagnosis that may lead to significant mortality and morbidity in both the developed and developing world; case fatality rates range from 10% to 50% among all age groups. Several vaccines are available (including the Haemophilus influenzae type B polysaccharide conjugate vaccine) ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-009-0045-z
更新日期:2009-07-01 00:00:00
abstract::Contact precautions are routinely employed for the control of multidrug-resistant organisms. Robust measures, however, for the incremental benefit of contact precautions, gowns, gloves, and active detection and isolation strategies for the prevention of cross-transmission in endemic settings are lacking. Unintended co...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-012-0299-8
更新日期:2012-12-01 00:00:00
abstract::The 2009 pandemic influenza A (H1N1) was responsible for the first influenza pandemic of the 21st century. The virus- a previously unknown triple-reassortant virus containing segments of avian, human, and swine origins- generally caused mild disease. Unlike seasonal influenza, 2009 pandemic influenza A (H1N1) primaril...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0157-5
更新日期:2011-04-01 00:00:00
abstract::Human herpesvirus 8 (HHV-8) or Kaposi's sarcoma (KS)-associated herpesvirus is a recently identified virus that is associated with KS, multicentric Castleman's disease, and body cavity-based lymphomas. KS is the most common kind of cancer in AIDS patients and the initial AIDS-defining condition in over 20% of patients...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-999-0031-5
更新日期:1999-08-01 00:00:00
abstract::Group A streptococcus is a widespread human pathogen that causes a broad spectrum of human disease. The persistent high burden and severity of illness in developing and industrialized countries speaks to the need for a safe and effective vaccine. Modern approaches to vaccine construction include M protein type-specifi...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-008-0032-9
更新日期:2008-05-01 00:00:00
abstract:PURPOSE OF REVIEW:This review highlights current knowledge in travel-related neuroinfectious diseases, providing insight on approaches to prevention, diagnosis, and treatment of infections of the central nervous system (CNS) in travelers and immigrants. RECENT FINDINGS:Updates on travel vaccine recommendations includi...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0594-5
更新日期:2017-10-03 00:00:00
abstract::Myocarditis is an acquired form inflammatory heart muscle disease, manifested as acute and chronic conditions. While many etiologies have been reported, the most common cause of this disease is infection, primarily viral. Typically, the specific causative agent(s) and mechanism(s) are elusive. Over the past several ye...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-000-0008-x
更新日期:2000-08-01 00:00:00
abstract::Although highly active antiretroviral therapy suppresses HIV replication resulting in extraordinary clinical benefits, toxicity, adherence difficulties, and the monetary cost of medications limit the long-term effectiveness and availability of therapy for many HIV-infected individuals. Strategies to interrupt therapy ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-002-0059-2
更新日期:2002-04-01 00:00:00
abstract:PURPOSE OF REVIEW:Post-transplant infections present a formidable challenge to the physician due to their varied presentation. Many of these infections begin by inoculation following skin compromise or disseminate to the skin hematogenously, making cutaneous manifestations of infection an important diagnostic clue in t...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-018-0621-1
更新日期:2018-05-22 00:00:00
abstract:PURPOSE OF REVIEW:Suppressive therapy and periodic presumptive treatment (PPT) are distinct but related strategies that have been used to reduce the incidence of bacterial vaginosis (BV). Here, we review clinical trial evidence of the effectiveness of suppressive therapy and PPT to reduce BV, and discuss their roles fo...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-019-0688-3
更新日期:2019-08-31 00:00:00
abstract:PURPOSE OF REVIEW:This review attempts to understand the reasons for the successes and failures of the two novel strategies that have slowly begun to emerge as potential counters for anti-malarial drug resistance-"Triple Combination Therapy" and "Drug Cycling." RECENT FINDINGS:Recent reports have suggested that increa...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0579-4
更新日期:2017-07-01 00:00:00
abstract::There is strong evidence that preoperative nasal S. aureus screening/decolonization will significantly reduce surgical site infections (SSIs) after joint prostheses implantation. There is some evidence that antibiotic-containing bone cement may lower SSI rates. Timely administration of perioperative systemic antibioti...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-012-0278-0
更新日期:2012-10-01 00:00:00
abstract::The dogma is that the higher risk of pyelonephritis in pregnant women is explained entirely by anatomic/obstructive changes. If so, gestational pyelonephritis should be caused by random, nonpathogenic bacteria. Instead, gestational pyelonephritis is associated with a narrow group of genetically related Escherichia col...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-002-0041-z
更新日期:2002-12-01 00:00:00
abstract:PURPOSE OF REVIEW:Since the treatment of acute diverticulitis has become more conservative over the last years, knowledge of conservative treatment strategies is increasingly important. RECENT FINDINGS:Several treatment strategies that previously have been imposed as routine treatment are now obsolete. Uncomplicated d...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0600-y
更新日期:2017-09-23 00:00:00
abstract::Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and cause a wide range of diseases in humans. Pulmonary involvement, the most common disease manifestation of NTM infection, is being increasingly encountered in clinical settings. In addition, specific phenotypic and genetic characteristics of person...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0103-6
更新日期:2010-05-01 00:00:00
abstract::In recent years, substantial advances have been achieved in the treatment of mucormycosis. It is now clear that early initiation of therapy results in substantially better outcomes, underscoring the need to maintain a high index of suspicion and aggressively biopsy potential lesions. Increasing data support the need f...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0129-9
更新日期:2010-11-01 00:00:00
abstract::About 1% of all patients with end-stage renal disease in the United States are infected with HIV. With the introduction of highly active antiretroviral therapy (HAART), HIV death rates have declined 80%, and chronic diseases resulting from HIV have replaced opportunistic infections as the leading cause of death among ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-009-0078-3
更新日期:2010-01-01 00:00:00
abstract::Hepatic failure due to hepatitis C is the leading indicator for orthotopic liver transplantation (OLT) in the United States. Unfortunately, recurrent hepatitis C virus infection is essentially universal following orthotopic liver transplantation. Although significant advances have been made in the past decade for the ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-002-0049-4
更新日期:2002-04-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this article is to perform a systematic review over the past 5 years on the role and effectiveness of clinical decision support systems (CDSSs) on antibiotic stewardship. RECENT FINDINGS:CDDS interventions found a significant impact on multiple outcomes relevant to antibiotic stewardsh...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-019-0683-8
更新日期:2019-07-24 00:00:00
abstract::Reduction of microbial contamination of the hospital environment is a challenge, yet has potential impacts on infection prevention efforts. Fumigation and UV light devices for environmental cleaning have expanded into the health care setting with the goal of decontamination of difficult to clean or overlooked surfaces...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-015-0498-1
更新日期:2015-09-01 00:00:00
abstract::Dermatologic manifestations of travel-related illness are particularly vexing due to the broad differential diagnosis and clinicians' unfamiliarity with uncommonly seen diseases. This paper aims to educate and update the reader on selected infectious diseases in the returned traveler whose disease manifestations are p...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-015-0467-8
更新日期:2015-03-01 00:00:00
abstract:PURPOSE OF REVIEW:The global emergence of antifungal resistance among Candida spp. and Aspergillus spp. is a growing threat to public health, driven largely by the expanding use of antifungals in both the clinical and agricultural settings. As treatment options remain limited, understanding mechanisms and risk factors ...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-019-0702-9
更新日期:2019-11-16 00:00:00