Abstract:
:The possibility that infection with Chlamydia pneumoniae may somehow contribute to the pathogenesis of atherosclerosis continues to be explored by researchers worldwide. A direct cause-and-effect relationship between the bacterium and subsequent development of atherosclerosis has yet to be proved. However, compelling indirect evidence continues to mount in favor of this association. In this article the most recent information on this topic is reviewed. Seroepidemiologic and histopathologic evidence will be highlighted, as well as recent animal models of infection and atherosclerosis. In addition, current studies looking at the association of antichlamydial antibiotic use and risk of adverse cardiovascular outcomes will be detailed.
journal_name
Curr Infect Dis Repjournal_title
Current infectious disease reportsauthors
O'Donnell JAdoi
10.1007/s11908-996-0021-9keywords:
subject
Has Abstractpub_date
1999-06-01 00:00:00pages
142-147issue
2eissn
1523-3847issn
1534-3146journal_volume
1pub_type
杂志文章abstract::Dermatologic manifestations of travel-related illness are particularly vexing due to the broad differential diagnosis and clinicians' unfamiliarity with uncommonly seen diseases. This paper aims to educate and update the reader on selected infectious diseases in the returned traveler whose disease manifestations are p...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-015-0467-8
更新日期:2015-03-01 00:00:00
abstract::Contact precautions are routinely employed for the control of multidrug-resistant organisms. Robust measures, however, for the incremental benefit of contact precautions, gowns, gloves, and active detection and isolation strategies for the prevention of cross-transmission in endemic settings are lacking. Unintended co...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-012-0299-8
更新日期:2012-12-01 00:00:00
abstract::Hepatic failure due to hepatitis C is the leading indicator for orthotopic liver transplantation (OLT) in the United States. Unfortunately, recurrent hepatitis C virus infection is essentially universal following orthotopic liver transplantation. Although significant advances have been made in the past decade for the ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-002-0049-4
更新日期:2002-04-01 00:00:00
abstract::All of the endemic mycoses have cutaneous and mucocutaneous manifestations that are most commonly seen when patients have disseminated infection. Biopsy of skin lesions is simple and safe and can assist in making a timely diagnosis of disseminated infection. Primary cutaneous inoculation infection has been reported wi...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-013-0352-2
更新日期:2013-10-01 00:00:00
abstract:PURPOSE OF REVIEW:This review aims to determine the effectiveness of the use of syndrome diagnosis in the evaluation of vaginitis and to make suggestions based on the review findings. RECENT FINDINGS:Vaginal discharge as the main symptom of vaginitis is unspecific. A randomized study of symptom-based diagnosis and tre...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0558-9
更新日期:2017-01-01 00:00:00
abstract::Although modern medicine has improved survival in congenital heart disease dramatically, the long-term course carries a risk of late complications. The incidence of infective endocarditis in adults with congenital heart disease is more than 10 times higher than that of the normal population. Identification of the high...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-003-0006-x
更新日期:2003-08-01 00:00:00
abstract::Although waterborne pathogens are relatively uncommon causes of cutaneous infections, these agents are being recognized with increasing frequency. Humans are exposed to water through a variety of recreational and occupational activities. Poor sanitary conditions in developing nations place the human populations at con...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-003-0020-z
更新日期:2003-10-01 00:00:00
abstract::Increases in sexually transmitted diseases (STDs) among men who have sex with men (MSM) have coincided with recent increases in sexual risk behaviors across the United States and Europe. The identification of same-sex sexual risk behavior in men and the subsequent risk for certain bacterial and viral infections requir...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-003-0050-6
更新日期:2003-04-01 00:00:00
abstract::Hepatitis C virus (HCV) infection is a significant cause of chronic liver disease with substantial long-term sequelae. Until very recently, therapies to cure HCV were hindered by high nonresponse rates and severe side effects. The first-generation protease inhibitor-containing regimens provided superior cure rates for...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-014-0413-1
更新日期:2014-08-01 00:00:00
abstract::Healthcare-associated bacterial meningitis may occur after neurosurgical procedures, head trauma, and following placement of external or internal ventricular catheters. The likely microorganisms that cause meningitis in this setting (ie, staphylococci and gram-negative bacilli) are different from those that cause meni...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-011-0190-z
更新日期:2011-08-01 00:00:00
abstract::Community-acquired pneumonia (CAP) is one of the most common causes of morbidity and mortality in elderly and children. Vitamin C is known as a physiological antioxidant, regulating innate immune system in the lung. Vitamin C has been used to prevent and treat CAP. However, the use of vitamin C for preventing and trea...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-016-0530-0
更新日期:2016-08-01 00:00:00
abstract::The ability to predict efficacy and toxicity during antiretroviral therapy for HIV would be of obvious advantage. The substantial variability between patients in terms of bioavailability and distribution of current regimens is likely driven by genetic and environmental factors. Protease inhibitors and nucleoside/nucle...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-006-0052-2
更新日期:2006-09-01 00:00:00
abstract::Heavily pretreated HIV-infected patients with multidrug-resistant virus remain a clinical challenge to the treating physician. While the goal of therapy in such patients is still controversial, sustained immunologic and clinical benefit have only been demonstrated with complete suppression of plasma viral load below d...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-002-0089-9
更新日期:2002-06-01 00:00:00
abstract::Infections due to community-associated methicillin---resistant Staphylococcus aureus (CA-MRSA) are becoming more prevalent. CA-MRSA infections have unique epidemiologic features and virulence factors. Compared with health care-associated MRSA (HA-MRSA), most CA-MRSA is clonal type USA300 or 400 and has the Staphylococ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-008-0005-z
更新日期:2008-03-01 00:00:00
abstract::Human herpesvirus 8 (HHV-8) or Kaposi's sarcoma (KS)-associated herpesvirus is a recently identified virus that is associated with KS, multicentric Castleman's disease, and body cavity-based lymphomas. KS is the most common kind of cancer in AIDS patients and the initial AIDS-defining condition in over 20% of patients...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-999-0031-5
更新日期:1999-08-01 00:00:00
abstract::The pathogenesis of vulvovaginal candidiasis, which is caused by Candida albicans, is poorly understood. Despite a strong protective role for cell-mediated immunity (CMI) against other mucosal candidal infections, numerous studies in humans and most animal models have revealed little to no role for CMI or other forms ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-003-0092-9
更新日期:2003-12-01 00:00:00
abstract::Community-acquired pneumonia is a common reason for hospitalization and leads to significant morbidity and mortality. There are published evidence-based guidelines for the diagnosis, treatment, and management of community-acquired pneumonia. Many countries, including the US, have developed national, publically reporte...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-014-0395-z
更新日期:2014-02-01 00:00:00
abstract::Neisseria gonorrhoeae is a common cause of genitourinary sexually transmitted infections. N. gonorrhoeae is an obligate human pathogen that has evidence of tissue-specific host interactions and diverse extragenital manifestations of infection both in adult and pediatric populations. The clinical presentation of extrag...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-006-0009-5
更新日期:2006-03-01 00:00:00
abstract::In an era of cost-consciousness in the delivery of medical care, the economics of healthcare delivery for HIV-infected persons has been an area of active interest. Interested parties include the payors of HIV care, particularly public insurers, who are paying for an increasing amount of the overall cost of HIV care in...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-000-0018-8
更新日期:2000-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Post-transplant infections present a formidable challenge to the physician due to their varied presentation. Many of these infections begin by inoculation following skin compromise or disseminate to the skin hematogenously, making cutaneous manifestations of infection an important diagnostic clue in t...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-018-0621-1
更新日期:2018-05-22 00:00:00
abstract::Myocarditis is an acquired form inflammatory heart muscle disease, manifested as acute and chronic conditions. While many etiologies have been reported, the most common cause of this disease is infection, primarily viral. Typically, the specific causative agent(s) and mechanism(s) are elusive. Over the past several ye...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-000-0008-x
更新日期:2000-08-01 00:00:00
abstract::Candida species remain the most frequently isolated fungi in intensive care unit (ICU) patients with severe sepsis or septic shock. Delayed antifungal therapy in these patients is a recognized risk factor for mortality. However, the diagnosis of invasive candidiasis remains difficult and is frequently delayed. Clinica...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-011-0204-x
更新日期:2011-10-01 00:00:00
abstract::Infectious myositis is defined as an infection of a skeletal muscle. Infectious myositis is most commonly caused by bacteria; however, a variety of viral, parasitic, and fungal agents may also cause myositis. The pathogenesis of nonbacterial infectious myositis is via direct or hematogenous infection of the musculatur...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0118-z
更新日期:2010-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Community-acquired pneumonia (CAP) is the cause of a considerable burden of morbidity and mortality among HIV-infected patients. The purpose of this study was to review recent literature for epidemiological trends and management of CAP in HIV patients. RECENT FINDINGS:While the specific infectious et...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0559-8
更新日期:2017-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to discuss the unique pathways of biofilm formation utilized by respiratory pathogens and current and future therapeutic strategies to inhibit biofilm formation or eradicate established biofilm in the context of these pathogens. Both nonselective and selective strategies ...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-019-0657-x
更新日期:2019-03-02 00:00:00
abstract:PURPOSE OF THE REVIEW:Community-acquired pneumonia (CAP) is still associated with a large burden and causes significant morbidity and mortality. Besides universal vaccination and antibiotic treatment, statins as adjunctive therapy may also have a beneficial role in the prevention and treatment of CAP. Our goal from thi...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0581-x
更新日期:2017-08-01 00:00:00
abstract:PURPOSE OF REVIEW:Since the treatment of acute diverticulitis has become more conservative over the last years, knowledge of conservative treatment strategies is increasingly important. RECENT FINDINGS:Several treatment strategies that previously have been imposed as routine treatment are now obsolete. Uncomplicated d...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0600-y
更新日期:2017-09-23 00:00:00
abstract::Antimicrobial resistance is a growing problem globally. The appearance and spread of bacteria that are resistant to most or all commonly available antibiotics has raised the specter of untreatable bacterial infections. The New Delhi metallo-beta-lactamase-1 (NDM-1) has received wide attention because of the extreme re...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-012-0252-x
更新日期:2012-06-01 00:00:00
abstract::Prosthetic valve endocarditis (PVE) due to mycobacteria is a rare but frequently fatal complication that may occur early after the surgical procedure, or even years later. Infection has been described with both mechanical and biologic valvular prosthesis. The most commonly implicated mycobacterial species belong to th...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0108-1
更新日期:2010-07-01 00:00:00
abstract::Patients with sepsis may require mechanical ventilation due to the acute respiratory distress syndrome (ARDS). It has become increasingly accepted that mechanical ventilation can contribute to lung injury in these patients. The modern concept of ventilator-induced lung injury is described in the context of alveolar ov...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-005-0007-z
更新日期:2005-09-01 00:00:00