NDM-1 and the Role of Travel in Its Dissemination.

Abstract:

:Antimicrobial resistance is a growing problem globally. The appearance and spread of bacteria that are resistant to most or all commonly available antibiotics has raised the specter of untreatable bacterial infections. The New Delhi metallo-beta-lactamase-1 (NDM-1) has received wide attention because of the extreme resistance it confers, its presence in many common pathogens, its rapid spread to multiple continents, and local nosocomial spread in some areas. Most early reports of infections were in individuals who had received medical care in the Indian subcontinent. This paper will explore the role of travelers in the movement of pathogens and microbial genetic material associated with resistance, with a special focus on the appearance and dispersal of bacteria carrying this mobile genetic element, bla (NDM-1), and the contributing factors, including growing long-distance travel and expansion of travel across international borders for medical, dental, and surgical care (medical tourism).

journal_name

Curr Infect Dis Rep

authors

Wilson ME,Chen LH

doi

10.1007/s11908-012-0252-x

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

213-26

issue

3

eissn

1523-3847

issn

1534-3146

journal_volume

14

pub_type

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