Current concept in the pathophysiology of hepatitis delta infection.

abstract：:Healthcare-associated bacterial meningitis may occur after neurosurgical procedures, head trauma, and following placement of external or internal ventricular catheters. The likely microorganisms that cause meningitis in this setting (ie, staphylococci and gram-negative bacilli) are different from those that cause meni...

journal_title：Current infectious disease reports

authors： Laxmi S,Tunkel AR

更新日期：2011-08-01 00:00:00

abstract：:The ability to predict efficacy and toxicity during antiretroviral therapy for HIV would be of obvious advantage. The substantial variability between patients in terms of bioavailability and distribution of current regimens is likely driven by genetic and environmental factors. Protease inhibitors and nucleoside/nucle...

journal_title：Current infectious disease reports

authors： Owen A

更新日期：2006-09-01 00:00:00

abstract：:Pulmonary nocardiosis is an uncommon but serious infection that is increasingly found in immunosuppressed persons, especially transplant recipients and persons with AIDS. The Nocardia species are denizens of soil and decaying plants that gain entry to humans through inhalation or inoculation. Pulmonary nocardiosis typ...

journal_title：Current infectious disease reports

authors： Baracco GJ,Dickinson GM

更新日期：2001-06-01 00:00:00

abstract：:The dogma is that the higher risk of pyelonephritis in pregnant women is explained entirely by anatomic/obstructive changes. If so, gestational pyelonephritis should be caused by random, nonpathogenic bacteria. Instead, gestational pyelonephritis is associated with a narrow group of genetically related Escherichia col...

journal_title：Current infectious disease reports

authors： Nowicki B

更新日期：2002-12-01 00:00:00

abstract：:Bacterial vaginosis (BV) is a common cause of vaginal discharge in women of childbearing age. In some individuals, it recurs frequently after treatment, frustrating both the patient and the physician. Standard BV treatment--metronidazole or clindamycin, administered either intravaginally or orally--is followed by rela...

journal_title：Current infectious disease reports

authors： Hay P

更新日期：2000-12-01 00:00:00

abstract：:A broad range of disorders can cause inflammation of the thyroid gland. True thyroid infections are rare and can result from a variety of microorganisms, of which bacteria are the most common. Other rarer pathogens include fungi, parasites, and viruses. Gram-positive bacteria, especially staphylococci, predominate as ...

journal_title：Current infectious disease reports

authors： Shah SS,Baum SG

更新日期：2000-04-01 00:00:00

abstract：:Although highly active antiretroviral therapy suppresses HIV replication resulting in extraordinary clinical benefits, toxicity, adherence difficulties, and the monetary cost of medications limit the long-term effectiveness and availability of therapy for many HIV-infected individuals. Strategies to interrupt therapy ...

journal_title：Current infectious disease reports

authors： Dybul M

更新日期：2002-04-01 00:00:00

abstract：:Malaria is a devastating disease, inflicting epidemic morbidity and mortality with an estimated 500 million cases and 2.5 million deaths annually. Children suffer the most severe morbidity; one child dies of malaria every 30 seconds, accounting for over 1 million of the deaths annually. There continues to be a tremend...

journal_title：Current infectious disease reports

authors： Stauffer WM,Kamat D

更新日期：2003-02-01 00:00:00

abstract：Purpose of Review:In December 2019, outbreaks of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected pneumonia patients were discovered in Wuhan City, Hubei Province, China. With the spread of the epidemic, new cases have been found in other regions of China and abroad. This review summarizes the curr...

journal_title：Current infectious disease reports

authors： Wang Y,Wang L,Li X,Gong Z

更新日期：2020-01-01 00:00:00

abstract：:Neurocysticercosis, caused by infection with the pork tapeworm Taenia solium, is increasingly recognized as a cause of neurologic disease worldwide. Because the clinical presentation is nonspecific, diagnosis has been difficult. Advances in imaging studies and serodiagnostic techniques are facilitating the diagnosis o...

journal_title：Current infectious disease reports

authors： Yancey LS,Diaz-Marchan PJ,White AC

更新日期：2005-01-01 00:00:00

abstract：:Antimicrobial resistance is a growing problem globally. The appearance and spread of bacteria that are resistant to most or all commonly available antibiotics has raised the specter of untreatable bacterial infections. The New Delhi metallo-beta-lactamase-1 (NDM-1) has received wide attention because of the extreme re...

journal_title：Current infectious disease reports

authors： Wilson ME,Chen LH

更新日期：2012-06-01 00:00:00

abstract：:All of the endemic mycoses have cutaneous and mucocutaneous manifestations that are most commonly seen when patients have disseminated infection. Biopsy of skin lesions is simple and safe and can assist in making a timely diagnosis of disseminated infection. Primary cutaneous inoculation infection has been reported wi...

journal_title：Current infectious disease reports

authors： Smith JA,Riddell J 4th,Kauffman CA

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this article is to perform a systematic review over the past 5 years on the role and effectiveness of clinical decision support systems (CDSSs) on antibiotic stewardship. RECENT FINDINGS:CDDS interventions found a significant impact on multiple outcomes relevant to antibiotic stewardsh...

journal_title：Current infectious disease reports

authors： Rittmann B,Stevens MP

更新日期：2019-07-24 00:00:00

abstract：:Combination antifungal therapy has been an area of great research and clinical interest since antifungals became available decades ago, in part driven by the severe morbidity and mortality associated with invasive fungal infections. Because of the availability of newer antifungal agents including echinocandins and exp...

journal_title：Current infectious disease reports

authors： Baddley JW,Pappas PG

更新日期：2007-11-01 00:00:00

abstract：:Fungi are common inhabitants of the oral and nasal mucosa, and therefore the differentiation between colonization and pathogenicity in the setting of upper respiratory tract infection symptoms can be difficult. Fungal head and neck infections occur in both immunocompetent and immunocompromised persons, and patients wi...

journal_title：Current infectious disease reports

authors： Miller DJ

更新日期：2002-06-01 00:00:00

abstract：:Treatment of chronic rhinosinusitis still represents an unmet medical need. Presently, the US Food and Drug Administration has not approved any drugs for the treatment of this common condition. Various inflammatory processes are involved in the pathogenesis of chronic rhinosinusitis. Treatment of infection and surgica...

journal_title：Current infectious disease reports

authors： Hatipo U,Rubinstein I

更新日期：2007-05-01 00:00:00

abstract：:Endocarditis pathogens colonize valves with pre-existing sterile vegetations or valves with minimal endothelial lesions. Inflamed endothelia produce cytokines, integrins, and tissue factor, which in turn attract fibronectin, monocytes, and platelets. Bacteria attaching to such structures further activate the cascade, ...

journal_title：Current infectious disease reports

authors： Widmer E,Que YA,Entenza JM,Moreillon P

更新日期：2006-06-01 00:00:00

abstract：:Community-acquired pneumonia is a common reason for hospitalization and leads to significant morbidity and mortality. There are published evidence-based guidelines for the diagnosis, treatment, and management of community-acquired pneumonia. Many countries, including the US, have developed national, publically reporte...

journal_title：Current infectious disease reports

authors： Richey EA,Dudley L,Liu SK

更新日期：2014-02-01 00:00:00

abstract：:A variety of antigen-capture assays are commercially available for the detection of influenza. In addition, real-time multiplex polymerase chain reaction (PCR) has been used to detect influenza A and B in clinical specimens. The commercial assays can be completed in less than 30 minutes and have a sensitivity of at le...

journal_title：Current infectious disease reports

authors： Pachucki CT

更新日期：2005-05-01 00:00:00

abstract：:Carbapenems are the broadest spectrum antimicrobials utilized in the treatment of serious infections since the 1980s. Soon after their introduction, the discovery of carbapenem-resistant Enterobacteriaceae (CRE) was reported in the 1990s. Invasive CRE infections are associated with high mortality and limited treatment...

journal_title：Current infectious disease reports

authors： Bowers DR,Huang V

更新日期：2016-12-01 00:00:00

abstract：:Increases in sexually transmitted diseases (STDs) among men who have sex with men (MSM) have coincided with recent increases in sexual risk behaviors across the United States and Europe. The identification of same-sex sexual risk behavior in men and the subsequent risk for certain bacterial and viral infections requir...

journal_title：Current infectious disease reports

authors： Klausner JD,Wong W

更新日期：2003-04-01 00:00:00

abstract：:Africa carries a disproportionate burden of the global HIV endemic, accounting for two thirds of the global 33.3 million people living with HIV. While tremendous advances have been made in addressing the HIV epidemic in Africa, considerable challenges remain. Testing for HIV increased by 86% from 2007 to 2009 but more...

journal_title：Current infectious disease reports

authors： Gilliam BL,Patel D,Talwani R,Temesgen Z

更新日期：2012-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Post-transplant infections present a formidable challenge to the physician due to their varied presentation. Many of these infections begin by inoculation following skin compromise or disseminate to the skin hematogenously, making cutaneous manifestations of infection an important diagnostic clue in t...

journal_title：Current infectious disease reports

authors： Pettit CJ,Mazurek K,Kaffenberger B

更新日期：2018-05-22 00:00:00

abstract：PURPOSE OF REVIEW:Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system most often characterized by clinical relapses and periods of remission. RECENT FINDINGS:The past decade has seen a dramatic increase in disease-modifying therapies for MS. Fourteen FDA-approved immunomodulato...

journal_title：Current infectious disease reports

authors： Levin SN,Kaplan TB

更新日期：2017-02-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a significant cause of chronic liver disease with substantial long-term sequelae. Until very recently, therapies to cure HCV were hindered by high nonresponse rates and severe side effects. The first-generation protease inhibitor-containing regimens provided superior cure rates for...

journal_title：Current infectious disease reports

authors： Moore C,Levitsky J

更新日期：2014-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to review therapies with new mechanisms of action for the treatment of HIV that are at least in phase 2 clinical trials. RECENT FINDINGS:There are several new mechanisms of action being represented within clinical development, including histone deacetylase (HDAC) inhibito...

journal_title：Current infectious disease reports

authors： Gravatt LAH,Leibrand CR,Patel S,McRae M

更新日期：2017-09-19 00:00:00

abstract：:Ventilator-associated pneumonia (VAP), an infection of the lower respiratory tract which occurs in association with mechanical ventilation, is one of the most common causes of nosocomial infection in the intensive care unit (ICU). VAP causes significant morbidity and mortality in critically ill patients including incr...

journal_title：Current infectious disease reports

authors： Waters B,Muscedere J

更新日期：2015-08-01 00:00:00

abstract：:Acute otitis media (AOM), when associated with a bulging or full tympanic membrane, has a bacterial etiology in more than 90% of cases. Not infrequently, the organisms present express resistance mechanisms to commonly prescribed antibiotic therapy. Tympanocentesis is a procedure advocated by several national guideline...

journal_title：Current infectious disease reports

authors： Pichichero ME,Wright T

更新日期：2006-05-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to discuss the unique pathways of biofilm formation utilized by respiratory pathogens and current and future therapeutic strategies to inhibit biofilm formation or eradicate established biofilm in the context of these pathogens. Both nonselective and selective strategies ...

journal_title：Current infectious disease reports

authors： Hamilos DL

更新日期：2019-03-02 00:00:00

abstract：:Two million of the 15 million (13.3%) new cases of sexually transmitted infections (STIs) among persons 15 to 49 years old occur in pregnant women. Access to care and a provider's ability to assess risk, screen, and treat STIs are critical factors in preventing adverse pregnancy outcomes. Significant variations in pro...

journal_title：Current infectious disease reports

authors： Johnson HL,Erbelding EJ,Ghanem KG

更新日期：2007-03-01 00:00:00