Recurrent Bacterial Vaginosis.

Abstract:

:Bacterial vaginosis (BV) is a common cause of vaginal discharge in women of childbearing age. In some individuals, it recurs frequently after treatment, frustrating both the patient and the physician. Standard BV treatment--metronidazole or clindamycin, administered either intravaginally or orally--is followed by relapse in approximately 30% of cases, within one month. Our inability to prevent relapse reflects our lack of understanding of how BV originates. BV has been associated with infectious morbidity in obstetrics and gynecology. Recent studies have found it to be a risk factor for HIV spread. These findings increase the need for us to be able to control recurrent BV and reduce its prevalence in the general population.

journal_name

Curr Infect Dis Rep

authors

Hay P

doi

10.1007/s11908-000-0053-5

keywords:

subject

Has Abstract

pub_date

2000-12-01 00:00:00

pages

506-512

issue

6

eissn

1523-3847

issn

1534-3146

journal_volume

2

pub_type

杂志文章
  • Nonbacterial myositis.

    abstract::Infectious myositis is defined as an infection of a skeletal muscle. Infectious myositis is most commonly caused by bacteria; however, a variety of viral, parasitic, and fungal agents may also cause myositis. The pathogenesis of nonbacterial infectious myositis is via direct or hematogenous infection of the musculatur...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-010-0118-z

    authors: Crum-Cianflone NF

    更新日期:2010-09-01 00:00:00

  • Influenza vaccination in oncology patients.

    abstract::It is well established that the immunological response to the seasonal trivalent influenza vaccine is attenuated in cancer patients. Furthermore, rates of seroprotection and seroconversion vary by malignancy type and are higher in patients with solid tumors, as compared either with those with hematologic malignancies ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-013-0368-7

    authors: Baluch A,Pasikhova Y

    更新日期:2013-12-01 00:00:00

  • Urinary tract infection in women: new pathogenic considerations.

    abstract::Urinary tract infection (UTI) is a common clinical syndrome in women. Most UTIs are caused by Escherichia coli. UTI has become a productive and accessible model system for studying the molecular details of how bacteria interact with mucosal surfaces and the nature of the host response. Important advances in the past y...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-006-0021-9

    authors: Stapleton AE

    更新日期:2006-11-01 00:00:00

  • Renal Transplantation in HIV-Positive Recipients.

    abstract::About 1% of all patients with end-stage renal disease in the United States are infected with HIV. With the introduction of highly active antiretroviral therapy (HAART), HIV death rates have declined 80%, and chronic diseases resulting from HIV have replaced opportunistic infections as the leading cause of death among ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-009-0078-3

    authors: Locke JE,Segev DL

    更新日期:2010-01-01 00:00:00

  • How Might We Cure HIV?

    abstract::Antiretroviral therapy (ART) does not eliminate HIV-1 from latently infected reservoirs, and this remains the critical obstacle to the eradication of infection. Although ART is effective in suppressing viral load, life-long ART is burdensome in many respects. Given expanding numbers of HIV-infected individuals on ART ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-014-0392-2

    authors: Margolis DM

    更新日期:2014-03-01 00:00:00

  • Special Challenges in the Prevention and Treatment of Malaria in Children.

    abstract::Malaria is a devastating disease, inflicting epidemic morbidity and mortality with an estimated 500 million cases and 2.5 million deaths annually. Children suffer the most severe morbidity; one child dies of malaria every 30 seconds, accounting for over 1 million of the deaths annually. There continues to be a tremend...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-003-0064-0

    authors: Stauffer WM,Kamat D

    更新日期:2003-02-01 00:00:00

  • Anti-inflammatory treatment of chronic rhinosinusitis: a shifting paradigm.

    abstract::Treatment of chronic rhinosinusitis still represents an unmet medical need. Presently, the US Food and Drug Administration has not approved any drugs for the treatment of this common condition. Various inflammatory processes are involved in the pathogenesis of chronic rhinosinusitis. Treatment of infection and surgica...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-007-0031-2

    authors: Hatipo U,Rubinstein I

    更新日期:2007-05-01 00:00:00

  • Ventilatory strategies in patients with sepsis and respiratory failure.

    abstract::Patients with sepsis may require mechanical ventilation due to the acute respiratory distress syndrome (ARDS). It has become increasingly accepted that mechanical ventilation can contribute to lung injury in these patients. The modern concept of ventilator-induced lung injury is described in the context of alveolar ov...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-005-0007-z

    authors: Hess DR,Thompson BT

    更新日期:2005-09-01 00:00:00

  • Mycobacterial prosthetic valve endocarditis.

    abstract::Prosthetic valve endocarditis (PVE) due to mycobacteria is a rare but frequently fatal complication that may occur early after the surgical procedure, or even years later. Infection has been described with both mechanical and biologic valvular prosthesis. The most commonly implicated mycobacterial species belong to th...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-010-0108-1

    authors: Bush LM,Paturi A,Chaparro-Rojas F,Perez MT

    更新日期:2010-07-01 00:00:00

  • Methicillin-resistant Staphylococcus aureus: from the hospital to the community.

    abstract::Infections due to community-associated methicillin---resistant Staphylococcus aureus (CA-MRSA) are becoming more prevalent. CA-MRSA infections have unique epidemiologic features and virulence factors. Compared with health care-associated MRSA (HA-MRSA), most CA-MRSA is clonal type USA300 or 400 and has the Staphylococ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-008-0005-z

    authors: Paez A,Skiest D

    更新日期:2008-03-01 00:00:00

  • Probiotics and prebiotics for the prevention of necrotizing enterocolitis.

    abstract::Necrotizing enterocolitis (NEC) continues to be a major cause of morbidity and mortality in premature infants. Although the pathogenesis of NEC remains unclear, abnormal bacterial colonization has been postulated as playing a central role. Various factors impact bacterial colonization following delivery. Compared to t...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-010-0156-6

    authors: Stenger MR,Reber KM,Giannone PJ,Nankervis CA

    更新日期:2011-02-01 00:00:00

  • Viral infections of the lower respiratory tract.

    abstract::Lower respiratory tract infections (LRTIs) are a global burden to public health and are frequently caused by respiratory viruses. Advances in molecular diagnostic techniques have allowed the identification of previously undetected viral pathogens and have improved our understanding of respiratory virus infections. Her...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-012-0258-4

    authors: Ren L,Xiang Z,Guo L,Wang J

    更新日期:2012-06-01 00:00:00

  • When and how to cover for fungal infections in patients with severe sepsis and septic shock.

    abstract::Candida species remain the most frequently isolated fungi in intensive care unit (ICU) patients with severe sepsis or septic shock. Delayed antifungal therapy in these patients is a recognized risk factor for mortality. However, the diagnosis of invasive candidiasis remains difficult and is frequently delayed. Clinica...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-011-0204-x

    authors: Allou N,Allyn J,Montravers P

    更新日期:2011-10-01 00:00:00

  • Clinical Pharmacologic Considerations for HIV-1 Protease Inhibitors.

    abstract::Many data associate low protease inhibitor plasma concentrations with suboptimal virologic responses, whereas relatively few data associate high plasma concentrations with increased likelihood of toxicity. Knowledge of relationships between concentrations and virologic response is important because significant variabi...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-001-0079-3

    authors: Anderson PL,Fletcher CV

    更新日期:2001-08-01 00:00:00

  • The use of tympanocentesis in the diagnosis and management of acute otitis media.

    abstract::Acute otitis media (AOM), when associated with a bulging or full tympanic membrane, has a bacterial etiology in more than 90% of cases. Not infrequently, the organisms present express resistance mechanisms to commonly prescribed antibiotic therapy. Tympanocentesis is a procedure advocated by several national guideline...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-006-0058-9

    authors: Pichichero ME,Wright T

    更新日期:2006-05-01 00:00:00

  • Rapid Tests for Influenza.

    abstract::A variety of antigen-capture assays are commercially available for the detection of influenza. In addition, real-time multiplex polymerase chain reaction (PCR) has been used to detect influenza A and B in clinical specimens. The commercial assays can be completed in less than 30 minutes and have a sensitivity of at le...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-005-0033-x

    authors: Pachucki CT

    更新日期:2005-05-01 00:00:00

  • Current Management of Onychomycosis and Dermatomycoses.

    abstract::Three newer oral antifungal agents, itraconazole, terbinafine and fluconazole, have revolutionized treatment of superficial mycoses. The tissue pharmacokinetics of itraconazole and terbinafine allow much shorter courses of therapy- with higher efficacy-in the treatment of onychomycosis, compared to other oral agents. ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-000-0074-0

    authors: Del Rosso JQ

    更新日期:2000-10-01 00:00:00

  • Pharmacokinetics of antibiotics or antifungal drugs in intensive care units.

    abstract::Intensive care unit (ICU) patients present several unusual pharmacokinetic (PK) characteristics compared with less seriously ill patients, including increased distribution volume and variable clearance. Interpatient PK variability is often considerable and can produce a wide range of values for PK parameters and major...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-009-0003-9

    authors: Dufour G,Montravers P

    更新日期:2009-01-01 00:00:00

  • Syndromic Diagnosis in Evaluation of Women with Symptoms of Vaginitis.

    abstract:PURPOSE OF REVIEW:This review aims to determine the effectiveness of the use of syndrome diagnosis in the evaluation of vaginitis and to make suggestions based on the review findings. RECENT FINDINGS:Vaginal discharge as the main symptom of vaginitis is unspecific. A randomized study of symptom-based diagnosis and tre...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-017-0558-9

    authors: Nwankwo TO,Aniebue UU,Umeh UA

    更新日期:2017-01-01 00:00:00

  • Cysticercosis: Recent Advances in Diagnosis and Management of Neurocysticercosis.

    abstract::Neurocysticercosis, caused by infection with the pork tapeworm Taenia solium, is increasingly recognized as a cause of neurologic disease worldwide. Because the clinical presentation is nonspecific, diagnosis has been difficult. Advances in imaging studies and serodiagnostic techniques are facilitating the diagnosis o...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-005-0022-0

    authors: Yancey LS,Diaz-Marchan PJ,White AC

    更新日期:2005-01-01 00:00:00

  • An Update on Malaria Rapid Diagnostic Tests.

    abstract:PURPOSE OF REVIEW:Modern advances in malaria rapid diagnostic test (RDT) technology have increased demand for low-cost, easy-to-use assays in areas endemic for malaria. Substantial developments in diagnostic sensitivity and specificity, improvements in non-falciparum RDTs, and novel biotechnological innovations are gra...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-018-0655-4

    authors: Mukkala AN,Kwan J,Lau R,Harris D,Kain D,Boggild AK

    更新日期:2018-10-23 00:00:00

  • Diagnostic Investigation of Pyelonephritis.

    abstract::Urinary tract infections are common, especially among women, and cause significant morbidity. While prognosis is probably more dependent on whether or not an episode of urinary tract infection is complicated (ie, associated with functional, metabolic, or anatomic abnormalities of the urinary tract) or uncomplicated, a...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-001-0090-8

    authors: Zandi-Nejad K,Brown PD

    更新日期:2001-12-01 00:00:00

  • Norovirus in Transplantation.

    abstract::Noroviruses are among the most common cause of diarrhea in transplant recipients. The clinical spectrum of norovirus infection after transplant is increasingly being recognized. As substantial morbidity is now associated with norovirus infections in this population; the quest for rapid diagnostic modalities and newer ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-016-0524-y

    authors: Angarone MP,Sheahan A,Kamboj M

    更新日期:2016-06-01 00:00:00

  • The prospect of vaccination against group A beta-hemolytic streptococci.

    abstract::Group A streptococcus is a widespread human pathogen that causes a broad spectrum of human disease. The persistent high burden and severity of illness in developing and industrialized countries speaks to the need for a safe and effective vaccine. Modern approaches to vaccine construction include M protein type-specifi...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-008-0032-9

    authors: Kotloff KL

    更新日期:2008-05-01 00:00:00

  • Recent Developments in the Epidemiology, Diagnosis, Treatment, and Prevention of Neurocysticercosis.

    abstract::Neuroimaging studies have revealed that neurocysticercosis is a major cause of neurologic disease in most developing countries and is an emerging disease in industrialized areas. Patients with neurocysticercosis present mainly with seizures (parenchymal form) or intracranial hypertension (ventricular/subarachnoid form...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-999-0055-x

    authors: White AC,Garcia HH

    更新日期:1999-12-01 00:00:00

  • The Twin Epidemics of Tuberculosis and HIV.

    abstract::The deadly combination of tuberculosis (TB) and human immunodeficiency virus (HIV) currently ravaging the world, taking a toll of about 0.35 million people every year, is one of the major public health crises of the decade. Throughout the course of HIV infection, the risk of acquisition, reactivation, and reinfection ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-012-0311-3

    authors: Varghese GM,Janardhanan J,Ralph R,Abraham OC

    更新日期:2013-02-01 00:00:00

  • Molecular Aspects of Myocarditis.

    abstract::Myocarditis is an acquired form inflammatory heart muscle disease, manifested as acute and chronic conditions. While many etiologies have been reported, the most common cause of this disease is infection, primarily viral. Typically, the specific causative agent(s) and mechanism(s) are elusive. Over the past several ye...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-000-0008-x

    authors: Bowles NE,Towbin JA

    更新日期:2000-08-01 00:00:00

  • Current concept in the pathophysiology of hepatitis delta infection.

    abstract::Hepatitis delta virus (HDV) is a unique human virus, showing similarities with plant viroids. Although impressive knowledge on virus structure and replication has been achieved, several questions like HBV/HDV interaction and post translational modifications of HD antigens remain to be answered. Potential targets for t...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-011-0233-5

    authors: Niro GA,Smedile A

    更新日期:2012-02-01 00:00:00

  • Sexually Transmitted Diseases in Men Who Have Sex with Men: A Clinical Review.

    abstract::Increases in sexually transmitted diseases (STDs) among men who have sex with men (MSM) have coincided with recent increases in sexual risk behaviors across the United States and Europe. The identification of same-sex sexual risk behavior in men and the subsequent risk for certain bacterial and viral infections requir...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-003-0050-6

    authors: Klausner JD,Wong W

    更新日期:2003-04-01 00:00:00

  • Quality improvement in hospital management of community-acquired pneumonia: focus on new strategies and current challenges.

    abstract::Community-acquired pneumonia is a common reason for hospitalization and leads to significant morbidity and mortality. There are published evidence-based guidelines for the diagnosis, treatment, and management of community-acquired pneumonia. Many countries, including the US, have developed national, publically reporte...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-014-0395-z

    authors: Richey EA,Dudley L,Liu SK

    更新日期:2014-02-01 00:00:00