The prospect of vaccination against group A beta-hemolytic streptococci.

Abstract:

:Group A streptococcus is a widespread human pathogen that causes a broad spectrum of human disease. The persistent high burden and severity of illness in developing and industrialized countries speaks to the need for a safe and effective vaccine. Modern approaches to vaccine construction include M protein type-specific vaccines, vaccines utilizing conserved M antigens, and vaccines based on other conserved surface-expressed or secreted antigens. Vaccine candidates in various stages of development offer promise for prevention of Group A streptococcal infections and their sequelae.

journal_name

Curr Infect Dis Rep

authors

Kotloff KL

doi

10.1007/s11908-008-0032-9

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

192-9

issue

3

eissn

1523-3847

issn

1534-3146

journal_volume

10

pub_type

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