CMV retinopathy in the antiretroviral therapy era: prevention, diagnosis, and management.

abstract：PURPOSE OF REVIEW:Suppressive therapy and periodic presumptive treatment (PPT) are distinct but related strategies that have been used to reduce the incidence of bacterial vaginosis (BV). Here, we review clinical trial evidence of the effectiveness of suppressive therapy and PPT to reduce BV, and discuss their roles fo...

journal_title：Current infectious disease reports

authors： Balkus JE,Carter KA,McClelland RS

更新日期：2019-08-31 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this paper is to review therapies with new mechanisms of action for the treatment of HIV that are at least in phase 2 clinical trials. RECENT FINDINGS:There are several new mechanisms of action being represented within clinical development, including histone deacetylase (HDAC) inhibito...

journal_title：Current infectious disease reports

authors： Gravatt LAH,Leibrand CR,Patel S,McRae M

更新日期：2017-09-19 00:00:00

abstract：PURPOSE OF REVIEW:This review highlights current knowledge in travel-related neuroinfectious diseases, providing insight on approaches to prevention, diagnosis, and treatment of infections of the central nervous system (CNS) in travelers and immigrants. RECENT FINDINGS:Updates on travel vaccine recommendations includi...

journal_title：Current infectious disease reports

authors： Thompson H,Thakur K

更新日期：2017-10-03 00:00:00

abstract：:Nontuberculous mycobacteria (NTM) are ubiquitous in the environment and cause a wide range of diseases in humans. Pulmonary involvement, the most common disease manifestation of NTM infection, is being increasingly encountered in clinical settings. In addition, specific phenotypic and genetic characteristics of person...

journal_title：Current infectious disease reports

authors： Saleeb P,Olivier KN

更新日期：2010-05-01 00:00:00

abstract：:Community-acquired pneumonia is a common reason for hospitalization and leads to significant morbidity and mortality. There are published evidence-based guidelines for the diagnosis, treatment, and management of community-acquired pneumonia. Many countries, including the US, have developed national, publically reporte...

journal_title：Current infectious disease reports

authors： Richey EA,Dudley L,Liu SK

更新日期：2014-02-01 00:00:00

abstract：:Therapy of cryptococcal meningitis has been focused primarily on optimizing the antifungal regimen to improve the previously high treatment failure rates. Until recently, relatively little attention has been paid to the impact of increased intracranial pressure, which is a frequent problem that complicates management ...

journal_title：Current infectious disease reports

authors： Gambarin KJ,Hamill RJ

更新日期：2002-08-01 00:00:00

abstract：:Acute otitis media (AOM), when associated with a bulging or full tympanic membrane, has a bacterial etiology in more than 90% of cases. Not infrequently, the organisms present express resistance mechanisms to commonly prescribed antibiotic therapy. Tympanocentesis is a procedure advocated by several national guideline...

journal_title：Current infectious disease reports

authors： Pichichero ME,Wright T

更新日期：2006-05-01 00:00:00

abstract：:Transmissible spongiform encephalopathies (TSEs) are a group of progressive, fatal neurodegenerative disorders that share a common spongiform histopathology. TSEs may be transmitted in a sporadic, familial, iatrogenic, or zoonotic fashion. The putative infectious agent of TSE, the prion, represents a novel paradigm of...

journal_title：Current infectious disease reports

authors： Janka J,Maldarelli F

更新日期：2004-08-01 00:00:00

abstract：:Infections due to community-associated methicillin---resistant Staphylococcus aureus (CA-MRSA) are becoming more prevalent. CA-MRSA infections have unique epidemiologic features and virulence factors. Compared with health care-associated MRSA (HA-MRSA), most CA-MRSA is clonal type USA300 or 400 and has the Staphylococ...

journal_title：Current infectious disease reports

authors： Paez A,Skiest D

更新日期：2008-03-01 00:00:00

abstract：:Arthroplasty of the knee and hip is a common procedure. There is a risk of infection with primary arthroplasty, with an incidence of 1% to 2%. Significant cost and morbidity are associated with infection of the prosthetic joint. Most infections (60% to 70%) are caused by staphylococci, but approximately 10% are caused...

journal_title：Current infectious disease reports

authors： Lentino JR

更新日期：2004-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection is a significant cause of chronic liver disease with substantial long-term sequelae. Until very recently, therapies to cure HCV were hindered by high nonresponse rates and severe side effects. The first-generation protease inhibitor-containing regimens provided superior cure rates for...

journal_title：Current infectious disease reports

authors： Moore C,Levitsky J

更新日期：2014-08-01 00:00:00

abstract：:Lower respiratory tract infections (LRTIs) are a global burden to public health and are frequently caused by respiratory viruses. Advances in molecular diagnostic techniques have allowed the identification of previously undetected viral pathogens and have improved our understanding of respiratory virus infections. Her...

journal_title：Current infectious disease reports

authors： Ren L,Xiang Z,Guo L,Wang J

更新日期：2012-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This review aims to determine the effectiveness of the use of syndrome diagnosis in the evaluation of vaginitis and to make suggestions based on the review findings. RECENT FINDINGS:Vaginal discharge as the main symptom of vaginitis is unspecific. A randomized study of symptom-based diagnosis and tre...

journal_title：Current infectious disease reports

authors： Nwankwo TO,Aniebue UU,Umeh UA

更新日期：2017-01-01 00:00:00

abstract：:Elderly are at high risk for hospitalization for community-acquired pneumonia (CAP), especially due to Streptococcus pneumoniae, and seasonal influenza viruses. Data suggest PPV23's influence on various CAP-related outcomes among the elderly may depend upon how many years have elapsed since they received this vaccine....

journal_title：Current infectious disease reports

authors： Gubbins PO,Li C

更新日期：2015-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Community-acquired pneumonia (CAP) is the cause of a considerable burden of morbidity and mortality among HIV-infected patients. The purpose of this study was to review recent literature for epidemiological trends and management of CAP in HIV patients. RECENT FINDINGS:While the specific infectious et...

journal_title：Current infectious disease reports

authors： Almeida A,Boattini M

更新日期：2017-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system most often characterized by clinical relapses and periods of remission. RECENT FINDINGS:The past decade has seen a dramatic increase in disease-modifying therapies for MS. Fourteen FDA-approved immunomodulato...

journal_title：Current infectious disease reports

authors： Levin SN,Kaplan TB

更新日期：2017-02-01 00:00:00

abstract：:The dogma is that the higher risk of pyelonephritis in pregnant women is explained entirely by anatomic/obstructive changes. If so, gestational pyelonephritis should be caused by random, nonpathogenic bacteria. Instead, gestational pyelonephritis is associated with a narrow group of genetically related Escherichia col...

journal_title：Current infectious disease reports

authors： Nowicki B

更新日期：2002-12-01 00:00:00

abstract：:Immunization against the most common meningeal pathogens is the leading factor associated with decreased incidence of bacterial meningitis in countries where routine vaccination is available. This is most dramatically illustrated by the reduction in the incidence of Haemophilus influenzae type b meningitis. The incide...

journal_title：Current infectious disease reports

authors： Dery MA,Hasbun R

更新日期：2007-07-01 00:00:00

abstract：:Three newer oral antifungal agents, itraconazole, terbinafine and fluconazole, have revolutionized treatment of superficial mycoses. The tissue pharmacokinetics of itraconazole and terbinafine allow much shorter courses of therapy- with higher efficacy-in the treatment of onychomycosis, compared to other oral agents. ...

journal_title：Current infectious disease reports

authors： Del Rosso JQ

更新日期：2000-10-01 00:00:00

abstract：:Heavily pretreated HIV-infected patients with multidrug-resistant virus remain a clinical challenge to the treating physician. While the goal of therapy in such patients is still controversial, sustained immunologic and clinical benefit have only been demonstrated with complete suppression of plasma viral load below d...

journal_title：Current infectious disease reports

authors： Montaner JS,Harris M

更新日期：2002-06-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Patients with COPD are at increased risk for community-acquired pneumonia (CAP). COPD has been reported as a comorbidity in at least one third of the hospitalized patients with CAP. There is a controversy that the pre...

journal_title：Current infectious disease reports

authors： Cilli A

更新日期：2015-01-01 00:00:00

abstract：:Increases in sexually transmitted diseases (STDs) among men who have sex with men (MSM) have coincided with recent increases in sexual risk behaviors across the United States and Europe. The identification of same-sex sexual risk behavior in men and the subsequent risk for certain bacterial and viral infections requir...

journal_title：Current infectious disease reports

authors： Klausner JD,Wong W

更新日期：2003-04-01 00:00:00

abstract：:Bacterial meningitis remains a feared diagnosis that may lead to significant mortality and morbidity in both the developed and developing world; case fatality rates range from 10% to 50% among all age groups. Several vaccines are available (including the Haemophilus influenzae type B polysaccharide conjugate vaccine) ...

journal_title：Current infectious disease reports

authors： Verma R,Fisher MC

更新日期：2009-07-01 00:00:00

abstract：:Colonization with Staphylococcus aureus is a risk factor for invasive S. aureus infections. Intranasal mupirocin has effectively eradicated S. aureus colonization and appears to prevent S. aureus nosocomial infections in some patient populations. In hospitals and communities where mupirocin use has been widespread, re...

journal_title：Current infectious disease reports

authors： Polgreen PM,Herwaldt LA

更新日期：2004-12-01 00:00:00

abstract：:During much of the past century, the microbe itself stood at the heart of microbial pathogenesis. Little thought was devoted to the host per se, though it was granted that differences in susceptibility to certain infections did exist between individuals, and between different ethnic groups. During the past 20 years, e...

journal_title：Current infectious disease reports

authors： Beutler B,Ulevitch RJ

更新日期：2007-10-01 00:00:00

abstract：:Bacterial meningitis is a complex disorder in which neurologic injury is caused, in part, by the causative organism and, in part, by the host's own inflammatory response. In studies of experimental bacterial meningitis, adjuvant treatment with corticosteroids, specifically dexamethasone, has beneficial effects. On the...

journal_title：Current infectious disease reports

authors： van de Beek D,de Gans J

更新日期：2005-07-01 00:00:00

abstract：:Neisseria gonorrhoeae is a common cause of genitourinary sexually transmitted infections. N. gonorrhoeae is an obligate human pathogen that has evidence of tissue-specific host interactions and diverse extragenital manifestations of infection both in adult and pediatric populations. The clinical presentation of extrag...

journal_title：Current infectious disease reports

authors： Spencer SE,Bash MC

更新日期：2006-03-01 00:00:00

abstract：:In most high-income countries, fewer children now acquire meningitis, and many of those who do will survive. Globally, however, meningitis still remains a significant cause of child morbidity and mortality. In this article, the authors review recent evidence on the morbidity faced by childhood survivors of bacterial m...

journal_title：Current infectious disease reports

authors： Hudson LD,Viner RM,Christie D

更新日期：2013-06-01 00:00:00

abstract：:Although waterborne pathogens are relatively uncommon causes of cutaneous infections, these agents are being recognized with increasing frequency. Humans are exposed to water through a variety of recreational and occupational activities. Poor sanitary conditions in developing nations place the human populations at con...

journal_title：Current infectious disease reports

authors： Elko L,Rosenbach K,Sinnott J

更新日期：2003-10-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to discuss the unique pathways of biofilm formation utilized by respiratory pathogens and current and future therapeutic strategies to inhibit biofilm formation or eradicate established biofilm in the context of these pathogens. Both nonselective and selective strategies ...

journal_title：Current infectious disease reports

authors： Hamilos DL

更新日期：2019-03-02 00:00:00