Abstract：
:Immunization against the most common meningeal pathogens is the leading factor associated with decreased incidence of bacterial meningitis in countries where routine vaccination is available. This is most dramatically illustrated by the reduction in the incidence of Haemophilus influenzae type b meningitis. The incidence of bacterial meningitis has decreased by 55% since the introduction of the H. influenzae type b conjugate vaccine in 1990. H. influenzae occurred primarily in children younger than 5 years of age, and so the median age of patients with bacterial meningitis has now increased to 39 years of age in the United States, and the leading pathogen is currently Streptococcus pneumoniae. Three other control measures (ie, universal screening and antibiotic prophylaxis of pregnant women for Group B streptococci and the implementation and availability of the S. pneumoniae and Neisseria meningitidis conjugate vaccines) have likely further decreased the incidence of these meningeal pathogens. Lastly, the worldwide emergence of multidrug-resistant pneumococci has complicated the empiric therapy of bacterial meningitis.
journal_name
Curr Infect Dis Repjournal_title
Current infectious disease reportsauthors
Dery MA,Hasbun Rdoi
10.1007/s11908-007-0047-7subject
Has Abstractpub_date
2007-07-01 00:00:00pages
301-7issue
4eissn
1523-3847issn
1534-3146journal_volume
9pub_type
杂志文章abstract：PURPOSE OF REVIEW:This review highlights current knowledge in travel-related neuroinfectious diseases, providing insight on approaches to prevention, diagnosis, and treatment of infections of the central nervous system (CNS) in travelers and immigrants. RECENT FINDINGS:Updates on travel vaccine recommendations includi...
journal_title：Current infectious disease reports
pub_type： 杂志文章,评审
doi：10.1007/s11908-017-0594-5
更新日期：2017-10-03 00:00:00
abstract：:Bacterial meningitis remains a feared diagnosis that may lead to significant mortality and morbidity in both the developed and developing world; case fatality rates range from 10% to 50% among all age groups. Several vaccines are available (including the Haemophilus influenzae type B polysaccharide conjugate vaccine) ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-009-0045-z
更新日期：2009-07-01 00:00:00
abstract：PURPOSE OF REVIEW:The global emergence of antifungal resistance among Candida spp. and Aspergillus spp. is a growing threat to public health, driven largely by the expanding use of antifungals in both the clinical and agricultural settings. As treatment options remain limited, understanding mechanisms and risk factors ...
journal_title：Current infectious disease reports
pub_type： 杂志文章,评审
doi：10.1007/s11908-019-0702-9
更新日期：2019-11-16 00:00:00
abstract：:Although modern medicine has improved survival in congenital heart disease dramatically, the long-term course carries a risk of late complications. The incidence of infective endocarditis in adults with congenital heart disease is more than 10 times higher than that of the normal population. Identification of the high...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-003-0006-x
更新日期：2003-08-01 00:00:00
abstract：:Starting from 2010, the 13-valent pneumococcal conjugate vaccine (PCV13) was introduced in several countries. This paper discusses some of the problems recently emerged after PCV13 use and their clinical impact. The impact of PCV13 has been relevant and has saved millions of children and adults by severe infectious di...
journal_title：Current infectious disease reports
pub_type： 杂志文章,评审
doi：10.1007/s11908-018-0607-z
更新日期：2018-01-24 00:00:00
abstract：:Community-acquired pneumonia is a common reason for hospitalization and leads to significant morbidity and mortality. There are published evidence-based guidelines for the diagnosis, treatment, and management of community-acquired pneumonia. Many countries, including the US, have developed national, publically reporte...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-014-0395-z
更新日期：2014-02-01 00:00:00
abstract：:Elderly are at high risk for hospitalization for community-acquired pneumonia (CAP), especially due to Streptococcus pneumoniae, and seasonal influenza viruses. Data suggest PPV23's influence on various CAP-related outcomes among the elderly may depend upon how many years have elapsed since they received this vaccine....
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-015-0505-6
更新日期：2015-12-01 00:00:00
abstract：:Bacterial vaginosis (BV) is a common cause of vaginal discharge in women of childbearing age. In some individuals, it recurs frequently after treatment, frustrating both the patient and the physician. Standard BV treatment--metronidazole or clindamycin, administered either intravaginally or orally--is followed by rela...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-000-0053-5
更新日期：2000-12-01 00:00:00
abstract：:Infectious myositis is defined as an infection of a skeletal muscle. Infectious myositis is most commonly caused by bacteria; however, a variety of viral, parasitic, and fungal agents may also cause myositis. The pathogenesis of nonbacterial infectious myositis is via direct or hematogenous infection of the musculatur...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-010-0118-z
更新日期：2010-09-01 00:00:00
abstract：:Coronary heart disease (CHD) is an inflammatory process that takes decades to develop. In HIV-seronegative persons, high-sensitivity C-reactive protein is a biologic marker of CHD risk. HIV infection induces chronic inflammation, despite adequate suppression of HIV replication with antiretroviral therapy, resulting in...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-010-0153-9
更新日期：2011-02-01 00:00:00
abstract：:Vaginal discharge, vulvar pruritus, and dyspareunia are among the most common symptoms that prompt women to seek medical advice. They are frequently assumed to be due to vaginitis resulting from infection and are treated with anti-infective agents without further investigation. Such empirical treatment may be successf...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-008-0079-7
更新日期：2008-11-01 00:00:00
abstract：:Skin lesions provide an important clue to the diagnoses of many infections in returned travelers. New information related to epidemiology, recognition, diagnosis, or management is described for the systemic infections--dengue fever, several of the rickettsial infections, African trypanosomiasis, and coccidioidomycosis...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-004-0025-2
更新日期：2004-02-01 00:00:00
abstract：:Although most cases of rhinosinusitis are benign, the disruption of quality of life due to disease symptoms leads patients to seek early medical care. Ongoing debates dispute the definition, bacteriology, and medical management of chronic sinusitis, while the criteria for acute sinusitis are relatively well establishe...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-001-0022-7
更新日期：2001-06-01 00:00:00
abstract：:Antiretroviral therapy (ART) does not eliminate HIV-1 from latently infected reservoirs, and this remains the critical obstacle to the eradication of infection. Although ART is effective in suppressing viral load, life-long ART is burdensome in many respects. Given expanding numbers of HIV-infected individuals on ART ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-014-0392-2
更新日期：2014-03-01 00:00:00
abstract：:Although highly active antiretroviral therapy suppresses HIV replication resulting in extraordinary clinical benefits, toxicity, adherence difficulties, and the monetary cost of medications limit the long-term effectiveness and availability of therapy for many HIV-infected individuals. Strategies to interrupt therapy ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-002-0059-2
更新日期：2002-04-01 00:00:00
abstract：:Antipsychotics are generally distinguished as atypical and typical agents, which are indicated in the treatment of acute and chronic psychoses and other psychiatric disorders. In April 2005, the US Food and Drug Administration issued a warning about the increased risk of all-cause mortality associated with atypical an...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-011-0175-y
更新日期：2011-06-01 00:00:00
abstract：:Bacterial meningitis is a complex disorder in which neurologic injury is caused, in part, by the causative organism and, in part, by the host's own inflammatory response. In studies of experimental bacterial meningitis, adjuvant treatment with corticosteroids, specifically dexamethasone, has beneficial effects. On the...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-005-0061-6
更新日期：2005-07-01 00:00:00
abstract：:Invasive fungal infection (IFI) is an important cause of morbidity and mortality in patients with hematologic malignancy, prolonged neutropenia, or after hematopoietic stem cell transplant. Antifungal prophylaxis prevents IFI in high-risk hematology patients. This article discusses recent developments in antifungal pr...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-009-0061-z
更新日期：2009-11-01 00:00:00
abstract：:Reduction of microbial contamination of the hospital environment is a challenge, yet has potential impacts on infection prevention efforts. Fumigation and UV light devices for environmental cleaning have expanded into the health care setting with the goal of decontamination of difficult to clean or overlooked surfaces...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-015-0498-1
更新日期：2015-09-01 00:00:00
abstract：:Contact precautions are routinely employed for the control of multidrug-resistant organisms. Robust measures, however, for the incremental benefit of contact precautions, gowns, gloves, and active detection and isolation strategies for the prevention of cross-transmission in endemic settings are lacking. Unintended co...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-012-0299-8
更新日期：2012-12-01 00:00:00
abstract：:In an era of cost-consciousness in the delivery of medical care, the economics of healthcare delivery for HIV-infected persons has been an area of active interest. Interested parties include the payors of HIV care, particularly public insurers, who are paying for an increasing amount of the overall cost of HIV care in...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-000-0018-8
更新日期：2000-08-01 00:00:00
abstract：PURPOSE OF REVIEW:The purpose of this review is to investigate the evolution and epidemiology of Klebsiella pneumoniae carbapenemase (KPC)-producing organisms and the current and future treatment options for infections caused by KPC-producing isolates. RECENT FINDINGS:The emergence of resistance in Enterobacteriaceae ...
journal_title：Current infectious disease reports
pub_type： 杂志文章,评审
doi：10.1007/s11908-018-0617-x
更新日期：2018-05-05 00:00:00
abstract：:All of the endemic mycoses have cutaneous and mucocutaneous manifestations that are most commonly seen when patients have disseminated infection. Biopsy of skin lesions is simple and safe and can assist in making a timely diagnosis of disseminated infection. Primary cutaneous inoculation infection has been reported wi...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-013-0352-2
更新日期：2013-10-01 00:00:00
abstract：:Streptococcus bovis is a rare, but important cause of bacterial meningitis in children. Since its discovery in the early 1970s, the pathogen has undergone multiple taxonomic changes producing four distinct subspecies today, the most prevalent of which is S. gallolyticus subsp pasteurianus in infants and children. Whil...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-016-0519-8
更新日期：2016-03-01 00:00:00
abstract：:Diarrhea is one of the most common health problems among travelers. Although enterotoxigenic Escherichia coli is implicated most commonly, enteroaggregative E. coli has recently been described as a major pathogen. Shigella, Campylobacter, and Salmonella organisms are less common causes of acute diarrhea, and intestina...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-002-0070-7
更新日期：2002-02-01 00:00:00
abstract：:In the United States each year, influenza accounts for an estimated 20,000 to 40,000 deaths, nearly 300,000 hospitalizations, and millions of days lost from work. In the past few years, there has been an explosion of information in the medical literature related to influenza. This paper reviews these latest developmen...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-000-0039-3
更新日期：2000-06-01 00:00:00
abstract：:The pathogenesis of vulvovaginal candidiasis, which is caused by Candida albicans, is poorly understood. Despite a strong protective role for cell-mediated immunity (CMI) against other mucosal candidal infections, numerous studies in humans and most animal models have revealed little to no role for CMI or other forms ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-003-0092-9
更新日期：2003-12-01 00:00:00
abstract：:Although mixed infections are known to be clinically relevant in conditions such as nosocomial pneumonia and ventilator-related pneumonia, it is increasingly recognized that a substantial number of community-acquired lower respiratory tract infections may also be attributed to more than one pathogenic organism. A bett...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-007-0017-0
更新日期：2007-01-01 00:00:00
abstract：:Clostridium difficile is a major cause of antibiotic-associated diarrhea. While treatment regimens for C. difficile have been available for decades, they remain less than optimal due to the frequent recurrences that occur after therapy is completed. Moreover, the morbidity and expense associated with C. difficile have...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-996-0032-6
更新日期：2001-04-01 00:00:00
abstract：:Rates of syphilis continue to increase in the United States and HIV-infected patients make up a large proportion of cases. The interaction between syphilis and HIV is complex and still incompletely understood. Although diagnosis and management of HIV-infected patients with syphilis is, in general, similar to HIV-uninf...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-010-0083-6
更新日期：2010-03-01 00:00:00
