Immune Regulation and Its Role in the Pathogenesis of Candida Vaginitis.

Abstract:

:The pathogenesis of vulvovaginal candidiasis, which is caused by Candida albicans, is poorly understood. Despite a strong protective role for cell-mediated immunity (CMI) against other mucosal candidal infections, numerous studies in humans and most animal models have revealed little to no role for CMI or other forms of acquired immunity against vaginal candidal infections. Studies suggest that this may be because of immunoregulatory mechanisms that inhibit more profound adaptive immune responses rather than the simple lack of responsiveness. Such regulatory mechanisms significantly influence the pathogenesis of Candida vaginitis.

journal_name

Curr Infect Dis Rep

authors

Fidel PL

doi

10.1007/s11908-003-0092-9

keywords:

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

488-493

issue

6

eissn

1523-3847

issn

1534-3146

journal_volume

5

pub_type

杂志文章
  • Dermatologic Infectious Diseases in International Travelers.

    abstract::Skin lesions provide an important clue to the diagnoses of many infections in returned travelers. New information related to epidemiology, recognition, diagnosis, or management is described for the systemic infections--dengue fever, several of the rickettsial infections, African trypanosomiasis, and coccidioidomycosis...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-004-0025-2

    authors: Wilson ME,Chen LH

    更新日期:2004-02-01 00:00:00

  • Touchless Technologies for Decontamination in the Hospital: a Review of Hydrogen Peroxide and UV Devices.

    abstract::Reduction of microbial contamination of the hospital environment is a challenge, yet has potential impacts on infection prevention efforts. Fumigation and UV light devices for environmental cleaning have expanded into the health care setting with the goal of decontamination of difficult to clean or overlooked surfaces...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-015-0498-1

    authors: Doll M,Morgan DJ,Anderson D,Bearman G

    更新日期:2015-09-01 00:00:00

  • Adjunctive Corticosteroids in Adults with Bacterial Meningitis.

    abstract::Bacterial meningitis is a complex disorder in which neurologic injury is caused, in part, by the causative organism and, in part, by the host's own inflammatory response. In studies of experimental bacterial meningitis, adjuvant treatment with corticosteroids, specifically dexamethasone, has beneficial effects. On the...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-005-0061-6

    authors: van de Beek D,de Gans J

    更新日期:2005-07-01 00:00:00

  • NDM-1 and the Role of Travel in Its Dissemination.

    abstract::Antimicrobial resistance is a growing problem globally. The appearance and spread of bacteria that are resistant to most or all commonly available antibiotics has raised the specter of untreatable bacterial infections. The New Delhi metallo-beta-lactamase-1 (NDM-1) has received wide attention because of the extreme re...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-012-0252-x

    authors: Wilson ME,Chen LH

    更新日期:2012-06-01 00:00:00

  • Current concept in the pathophysiology of hepatitis delta infection.

    abstract::Hepatitis delta virus (HDV) is a unique human virus, showing similarities with plant viroids. Although impressive knowledge on virus structure and replication has been achieved, several questions like HBV/HDV interaction and post translational modifications of HD antigens remain to be answered. Potential targets for t...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-011-0233-5

    authors: Niro GA,Smedile A

    更新日期:2012-02-01 00:00:00

  • Is Vitamin C Beneficial to Patients with CAP?

    abstract::Community-acquired pneumonia (CAP) is one of the most common causes of morbidity and mortality in elderly and children. Vitamin C is known as a physiological antioxidant, regulating innate immune system in the lung. Vitamin C has been used to prevent and treat CAP. However, the use of vitamin C for preventing and trea...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-016-0530-0

    authors: Li Y,Li G

    更新日期:2016-08-01 00:00:00

  • Influenza vaccination in oncology patients.

    abstract::It is well established that the immunological response to the seasonal trivalent influenza vaccine is attenuated in cancer patients. Furthermore, rates of seroprotection and seroconversion vary by malignancy type and are higher in patients with solid tumors, as compared either with those with hematologic malignancies ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-013-0368-7

    authors: Baluch A,Pasikhova Y

    更新日期:2013-12-01 00:00:00

  • Live virus vaccines in transplantation: friend or foe?

    abstract::Solid organ and hematopoietic stem cell transplant recipients may be exposed to diseases which may be prevented through live attenuated virus vaccines (LAVV). Because of their immunosuppression, these diseases can lead to severe complications in transplant recipients. Despite increasing evidence regarding the safety a...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-015-0472-y

    authors: Verolet CM,Posfay-Barbe KM

    更新日期:2015-04-01 00:00:00

  • Viral infections of the lower respiratory tract.

    abstract::Lower respiratory tract infections (LRTIs) are a global burden to public health and are frequently caused by respiratory viruses. Advances in molecular diagnostic techniques have allowed the identification of previously undetected viral pathogens and have improved our understanding of respiratory virus infections. Her...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-012-0258-4

    authors: Ren L,Xiang Z,Guo L,Wang J

    更新日期:2012-06-01 00:00:00

  • Community-Acquired Pneumonia in HIV-Positive Patients: an Update on Etiologies, Epidemiology and Management.

    abstract:PURPOSE OF REVIEW:Community-acquired pneumonia (CAP) is the cause of a considerable burden of morbidity and mortality among HIV-infected patients. The purpose of this study was to review recent literature for epidemiological trends and management of CAP in HIV patients. RECENT FINDINGS:While the specific infectious et...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-017-0559-8

    authors: Almeida A,Boattini M

    更新日期:2017-01-01 00:00:00

  • Cutaneous manifestations of endemic mycoses.

    abstract::All of the endemic mycoses have cutaneous and mucocutaneous manifestations that are most commonly seen when patients have disseminated infection. Biopsy of skin lesions is simple and safe and can assist in making a timely diagnosis of disseminated infection. Primary cutaneous inoculation infection has been reported wi...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-013-0352-2

    authors: Smith JA,Riddell J 4th,Kauffman CA

    更新日期:2013-10-01 00:00:00

  • Eosinophilia: causes and pathobiology in persons with prior exposures in tropical areas with an emphasis on parasitic infections.

    abstract::Eosinophilia in patients exposed to tropical or subtropical environments is caused most commonly by helminth (worm) infections. Besides a detailed exposure history, the diagnostic approach must consider other infections and noninfectious causes of eosinophilia, as treatments for many of these disorders differ. ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-006-0034-4

    authors: Kim YJ,Nutman TB

    更新日期:2006-01-01 00:00:00

  • 2009 Pandemic Influenza A (H1N1): Diagnosis, Management, and Prevention- Lessons Learned.

    abstract::The 2009 pandemic influenza A (H1N1) was responsible for the first influenza pandemic of the 21st century. The virus- a previously unknown triple-reassortant virus containing segments of avian, human, and swine origins- generally caused mild disease. Unlike seasonal influenza, 2009 pandemic influenza A (H1N1) primaril...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-010-0157-5

    authors: Swedish KA

    更新日期:2011-04-01 00:00:00

  • Diagnostic Investigation of Pyelonephritis.

    abstract::Urinary tract infections are common, especially among women, and cause significant morbidity. While prognosis is probably more dependent on whether or not an episode of urinary tract infection is complicated (ie, associated with functional, metabolic, or anatomic abnormalities of the urinary tract) or uncomplicated, a...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-001-0090-8

    authors: Zandi-Nejad K,Brown PD

    更新日期:2001-12-01 00:00:00

  • Risk-based antifungal prophylaxis in hematologic malignancy and stem cell transplantation.

    abstract::Invasive fungal infection (IFI) is an important cause of morbidity and mortality in patients with hematologic malignancy, prolonged neutropenia, or after hematopoietic stem cell transplant. Antifungal prophylaxis prevents IFI in high-risk hematology patients. This article discusses recent developments in antifungal pr...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-009-0061-z

    authors: Wolf J,Slavin MA

    更新日期:2009-11-01 00:00:00

  • The impact of host pharmacogenetics on antiretroviral drug disposition.

    abstract::The ability to predict efficacy and toxicity during antiretroviral therapy for HIV would be of obvious advantage. The substantial variability between patients in terms of bioavailability and distribution of current regimens is likely driven by genetic and environmental factors. Protease inhibitors and nucleoside/nucle...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-006-0052-2

    authors: Owen A

    更新日期:2006-09-01 00:00:00

  • Renal Transplantation in HIV-Positive Recipients.

    abstract::About 1% of all patients with end-stage renal disease in the United States are infected with HIV. With the introduction of highly active antiretroviral therapy (HAART), HIV death rates have declined 80%, and chronic diseases resulting from HIV have replaced opportunistic infections as the leading cause of death among ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-009-0078-3

    authors: Locke JE,Segev DL

    更新日期:2010-01-01 00:00:00

  • Infectious Complications of Novel Multiple Sclerosis Therapies.

    abstract:PURPOSE OF REVIEW:Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system most often characterized by clinical relapses and periods of remission. RECENT FINDINGS:The past decade has seen a dramatic increase in disease-modifying therapies for MS. Fourteen FDA-approved immunomodulato...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-017-0562-0

    authors: Levin SN,Kaplan TB

    更新日期:2017-02-01 00:00:00

  • Risk Factors for Drug-Resistant Cap in Immunocompetent Patients.

    abstract:PURPOSE OF REVIEW:The increase in drug-resistant community-acquired pneumonia (CAP) is an important problem all over the world. This article explores the current state of antimicrobial resistance of different bacteria that cause CAP and also assesses risk factors to identify those pathogens. RECENT FINDINGS:In the las...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-017-0565-x

    authors: Arancibia F,Ruiz M

    更新日期:2017-03-01 00:00:00

  • The prospect of vaccination against group A beta-hemolytic streptococci.

    abstract::Group A streptococcus is a widespread human pathogen that causes a broad spectrum of human disease. The persistent high burden and severity of illness in developing and industrialized countries speaks to the need for a safe and effective vaccine. Modern approaches to vaccine construction include M protein type-specifi...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-008-0032-9

    authors: Kotloff KL

    更新日期:2008-05-01 00:00:00

  • Staphylococcus aureus Colonization and Nosocomial Infections: Implications for Prevention.

    abstract::Colonization with Staphylococcus aureus is a risk factor for invasive S. aureus infections. Intranasal mupirocin has effectively eradicated S. aureus colonization and appears to prevent S. aureus nosocomial infections in some patient populations. In hospitals and communities where mupirocin use has been widespread, re...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-004-0062-x

    authors: Polgreen PM,Herwaldt LA

    更新日期:2004-12-01 00:00:00

  • The Use of Statins and Risk of Community-Acquired Pneumonia.

    abstract:PURPOSE OF THE REVIEW:Community-acquired pneumonia (CAP) is still associated with a large burden and causes significant morbidity and mortality. Besides universal vaccination and antibiotic treatment, statins as adjunctive therapy may also have a beneficial role in the prevention and treatment of CAP. Our goal from thi...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-017-0581-x

    authors: Batais MA,Khan AR,Bin Abdulhak AA

    更新日期:2017-08-01 00:00:00

  • A Virus-based Vaccine May Prevent Cervical Cancer.

    abstract::High-risk human papillomaviruses (HPVs) are now recognized as the etiologic agents of invasive cervical cancer, a major cancer in women. A single HPV type (type 16) is responsible for about 50% of the cancers. The major capsid protein of papillomaviruses, L1, when expressed by recombinant DNA technology, has the intri...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-005-0072-3

    authors: Gravitt PE,Shah KV

    更新日期:2005-03-01 00:00:00

  • Nonbacterial myositis.

    abstract::Infectious myositis is defined as an infection of a skeletal muscle. Infectious myositis is most commonly caused by bacteria; however, a variety of viral, parasitic, and fungal agents may also cause myositis. The pathogenesis of nonbacterial infectious myositis is via direct or hematogenous infection of the musculatur...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-010-0118-z

    authors: Crum-Cianflone NF

    更新日期:2010-09-01 00:00:00

  • Infections of the Central Nervous System in Returning Travelers and Immigrants.

    abstract:PURPOSE OF REVIEW:This review highlights current knowledge in travel-related neuroinfectious diseases, providing insight on approaches to prevention, diagnosis, and treatment of infections of the central nervous system (CNS) in travelers and immigrants. RECENT FINDINGS:Updates on travel vaccine recommendations includi...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-017-0594-5

    authors: Thompson H,Thakur K

    更新日期:2017-10-03 00:00:00

  • Conservative Treatment of Acute Colonic Diverticulitis.

    abstract:PURPOSE OF REVIEW:Since the treatment of acute diverticulitis has become more conservative over the last years, knowledge of conservative treatment strategies is increasingly important. RECENT FINDINGS:Several treatment strategies that previously have been imposed as routine treatment are now obsolete. Uncomplicated d...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-017-0600-y

    authors: van Dijk ST,Rottier SJ,van Geloven AAW,Boermeester MA

    更新日期:2017-09-23 00:00:00

  • CMV retinopathy in the antiretroviral therapy era: prevention, diagnosis, and management.

    abstract::Before the advent of antiretroviral therapy (ART), CMV retinitis was a common, debilitating opportunistic infection in the HIV-infected population. ART has had such a favorable impact on the prevention and management of CMV retinitis that it can be considered in some ways to be CMV therapy. Currently available CMV dir...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-012-0269-1

    authors: Barrett L,Walmsley S

    更新日期:2012-08-01 00:00:00

  • Multidrug Resistant Acinetobacter baumannii: Resistance by Any Other Name Would Still be Hard to Treat.

    abstract:PURPOSE OF REVIEW:Acinetobacter baumannii (AB) is an infamous nosocomial pathogen with a seemingly limitless capacity for antimicrobial resistance, leading to few treatment options and poor clinical outcomes. The debatably low pathogenicity and virulence of AB are juxtaposed by its exceptionally high rate of infection-...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章,评审

    doi:10.1007/s11908-019-0706-5

    authors: Butler DA,Biagi M,Tan X,Qasmieh S,Bulman ZP,Wenzler E

    更新日期:2019-11-16 00:00:00

  • The Microbiology and Management of Acute and Chronic Rhinosinusitis.

    abstract::Although most cases of rhinosinusitis are benign, the disruption of quality of life due to disease symptoms leads patients to seek early medical care. Ongoing debates dispute the definition, bacteriology, and medical management of chronic sinusitis, while the criteria for acute sinusitis are relatively well establishe...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-001-0022-7

    authors: Hadley JA

    更新日期:2001-06-01 00:00:00

  • Chlamydia Species and Mycoplasma pneumoniae.

    abstract::Chlamydia psittaci, Chlamydia pneumoniae, and Mycoplasma pneumoniae are a group of respiratory pathogens that have similar pulmonary and extrapulmonary manifestations. Recent studies suggest that C. pneumoniae and M. pneumoniae may play a role in the pathogenesis of asthma, but further studies are needed to delineate ...

    journal_title:Current infectious disease reports

    pub_type: 杂志文章

    doi:10.1007/s11908-999-0013-7

    authors: Atmar RL

    更新日期:1999-04-01 00:00:00