Live virus vaccines in transplantation: friend or foe?

Abstract:

:Solid organ and hematopoietic stem cell transplant recipients may be exposed to diseases which may be prevented through live attenuated virus vaccines (LAVV). Because of their immunosuppression, these diseases can lead to severe complications in transplant recipients. Despite increasing evidence regarding the safety and effectiveness of certain LAVV, these vaccines are still contraindicated for immunocompromised patients, such as transplant recipients. We review the available studies on LAVV, such as varicella zoster, measles-mumps-rubella, influenza, yellow fever, polio, and Japanese encephalitis vaccines in transplant patients. We discuss the current recommendations and the potential risks, as well as the expected benefits of LAVV immunization in this population.

journal_name

Curr Infect Dis Rep

authors

Verolet CM,Posfay-Barbe KM

doi

10.1007/s11908-015-0472-y

subject

Has Abstract

pub_date

2015-04-01 00:00:00

pages

472

issue

4

eissn

1523-3847

issn

1534-3146

journal_volume

17

pub_type

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