Abstract：
Purpose of Review:In December 2019, outbreaks of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected pneumonia patients were discovered in Wuhan City, Hubei Province, China. With the spread of the epidemic, new cases have been found in other regions of China and abroad. This review summarizes the current coronavirus disease 2019 (COVID-19) transmission pathways, high-risk factors, diagnostic points, pathogenesis, and therapeutic drugs to provide the prevention and treatment theories for COVID-19. Recent Findings:COVID-19 is highly contagious and is transmitted mainly through the respiratory tract. Most patients with SARS-CoV-2 infection have milder symptoms. Some patients will have mild disease in the early stage, suddenly exacerbate later, and eventually die of multiple organ failure caused by cytokine storm. The basis for clinical diagnosis of COVID-19 is not just the detection of viral nucleic acids as the gold standard. The diagnostic accuracy improves when viral nucleic acid test is combined with clinical symptoms, CT results, and biochemical tests. For the treatment of COVID-19, the specific antiviral agents have not been developed, except for symptomatic supportive treatments. Summary:The methods for detecting SARS-CoV-2 infection have become increasingly mature, but specific antiviral drugs for the treatment of COVID-19 have not yet been developed. Treatment must pay attention to the cytokine storm that leads to the seriousness of COVID-19.
journal_name
Curr Infect Dis Repjournal_title
Current infectious disease reportsauthors
Wang Y,Wang L,Li X,Gong Zdoi
10.1007/s11908-020-00738-7subject
Has Abstractpub_date
2020-01-01 00:00:00pages
30issue
11eissn
1523-3847issn
1534-3146pii
738journal_volume
22pub_type
杂志文章,评审abstract：:Infections due to community-associated methicillin---resistant Staphylococcus aureus (CA-MRSA) are becoming more prevalent. CA-MRSA infections have unique epidemiologic features and virulence factors. Compared with health care-associated MRSA (HA-MRSA), most CA-MRSA is clonal type USA300 or 400 and has the Staphylococ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-008-0005-z
更新日期：2008-03-01 00:00:00
abstract：:Pulmonary nocardiosis is an uncommon but serious infection that is increasingly found in immunosuppressed persons, especially transplant recipients and persons with AIDS. The Nocardia species are denizens of soil and decaying plants that gain entry to humans through inhalation or inoculation. Pulmonary nocardiosis typ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-001-0032-5
更新日期：2001-06-01 00:00:00
abstract：:There is strong evidence that preoperative nasal S. aureus screening/decolonization will significantly reduce surgical site infections (SSIs) after joint prostheses implantation. There is some evidence that antibiotic-containing bone cement may lower SSI rates. Timely administration of perioperative systemic antibioti...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-012-0278-0
更新日期：2012-10-01 00:00:00
abstract：:Invasive fungal infection (IFI) is an important cause of morbidity and mortality in patients with hematologic malignancy, prolonged neutropenia, or after hematopoietic stem cell transplant. Antifungal prophylaxis prevents IFI in high-risk hematology patients. This article discusses recent developments in antifungal pr...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-009-0061-z
更新日期：2009-11-01 00:00:00
abstract：:In most high-income countries, fewer children now acquire meningitis, and many of those who do will survive. Globally, however, meningitis still remains a significant cause of child morbidity and mortality. In this article, the authors review recent evidence on the morbidity faced by childhood survivors of bacterial m...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-013-0332-6
更新日期：2013-06-01 00:00:00
abstract：:Hepatic failure due to hepatitis C is the leading indicator for orthotopic liver transplantation (OLT) in the United States. Unfortunately, recurrent hepatitis C virus infection is essentially universal following orthotopic liver transplantation. Although significant advances have been made in the past decade for the ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-002-0049-4
更新日期：2002-04-01 00:00:00
abstract：:Infectious myositis is defined as an infection of a skeletal muscle. Infectious myositis is most commonly caused by bacteria; however, a variety of viral, parasitic, and fungal agents may also cause myositis. The pathogenesis of nonbacterial infectious myositis is via direct or hematogenous infection of the musculatur...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-010-0118-z
更新日期：2010-09-01 00:00:00
abstract：:This article reviews techniques of rapid testing and the effective diagnosis of streptococcal pharyngitis. Despite 50 years' study of streptococcal pharyngitis and 20 years' experience with rapid tests for its diagnosis, the subject continues to evolve. Rapid diagnostic tests have become more sensitive. Experts now co...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-004-0006-5
更新日期：2004-06-01 00:00:00
abstract：:Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections have been reported with increasing frequency from many parts of the world. Most infections involve the skin and soft tissue structures, and CA-MRSA is now the most commonly identifiable cause of purulent skin and soft tissue infectio...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-007-0061-9
更新日期：2007-09-01 00:00:00
abstract：:Skin and soft tissue infections vary widely in their nature and severity, and their nomenclature is complex. Most are readily recognized and easily treated, but more severe infections may masquerade in forms similar to those of more innocent infections, causing delay in diagnosis and treatment that may result in loss ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-002-0010-6
更新日期：2002-10-01 00:00:00
abstract：PURPOSE OF REVIEW:The global emergence of antifungal resistance among Candida spp. and Aspergillus spp. is a growing threat to public health, driven largely by the expanding use of antifungals in both the clinical and agricultural settings. As treatment options remain limited, understanding mechanisms and risk factors ...
journal_title：Current infectious disease reports
pub_type： 杂志文章,评审
doi：10.1007/s11908-019-0702-9
更新日期：2019-11-16 00:00:00
abstract：:Noroviruses are among the most common cause of diarrhea in transplant recipients. The clinical spectrum of norovirus infection after transplant is increasingly being recognized. As substantial morbidity is now associated with norovirus infections in this population; the quest for rapid diagnostic modalities and newer ...
journal_title：Current infectious disease reports
pub_type： 杂志文章,评审
doi：10.1007/s11908-016-0524-y
更新日期：2016-06-01 00:00:00
abstract：:Neisseria gonorrhoeae is a common cause of genitourinary sexually transmitted infections. N. gonorrhoeae is an obligate human pathogen that has evidence of tissue-specific host interactions and diverse extragenital manifestations of infection both in adult and pediatric populations. The clinical presentation of extrag...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-006-0009-5
更新日期：2006-03-01 00:00:00
abstract：:About 1% of all patients with end-stage renal disease in the United States are infected with HIV. With the introduction of highly active antiretroviral therapy (HAART), HIV death rates have declined 80%, and chronic diseases resulting from HIV have replaced opportunistic infections as the leading cause of death among ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-009-0078-3
更新日期：2010-01-01 00:00:00
abstract：:Lower respiratory tract infections (LRTIs) are a global burden to public health and are frequently caused by respiratory viruses. Advances in molecular diagnostic techniques have allowed the identification of previously undetected viral pathogens and have improved our understanding of respiratory virus infections. Her...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-012-0258-4
更新日期：2012-06-01 00:00:00
abstract：:The deadly combination of tuberculosis (TB) and human immunodeficiency virus (HIV) currently ravaging the world, taking a toll of about 0.35 million people every year, is one of the major public health crises of the decade. Throughout the course of HIV infection, the risk of acquisition, reactivation, and reinfection ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-012-0311-3
更新日期：2013-02-01 00:00:00
abstract：:Neuroimaging studies have revealed that neurocysticercosis is a major cause of neurologic disease in most developing countries and is an emerging disease in industrialized areas. Patients with neurocysticercosis present mainly with seizures (parenchymal form) or intracranial hypertension (ventricular/subarachnoid form...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-999-0055-x
更新日期：1999-12-01 00:00:00
abstract：:Bacterial vaginosis (BV) is a common cause of vaginal discharge in women of childbearing age. In some individuals, it recurs frequently after treatment, frustrating both the patient and the physician. Standard BV treatment--metronidazole or clindamycin, administered either intravaginally or orally--is followed by rela...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-000-0053-5
更新日期：2000-12-01 00:00:00
abstract：PURPOSE OF REVIEW:The purpose of this article is to perform a systematic review over the past 5 years on the role and effectiveness of clinical decision support systems (CDSSs) on antibiotic stewardship. RECENT FINDINGS:CDDS interventions found a significant impact on multiple outcomes relevant to antibiotic stewardsh...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-019-0683-8
更新日期：2019-07-24 00:00:00
abstract：:Immunization against the most common meningeal pathogens is the leading factor associated with decreased incidence of bacterial meningitis in countries where routine vaccination is available. This is most dramatically illustrated by the reduction in the incidence of Haemophilus influenzae type b meningitis. The incide...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-007-0047-7
更新日期：2007-07-01 00:00:00
abstract：:Two million of the 15 million (13.3%) new cases of sexually transmitted infections (STIs) among persons 15 to 49 years old occur in pregnant women. Access to care and a provider's ability to assess risk, screen, and treat STIs are critical factors in preventing adverse pregnancy outcomes. Significant variations in pro...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-007-0008-1
更新日期：2007-03-01 00:00:00
abstract：:The dogma is that the higher risk of pyelonephritis in pregnant women is explained entirely by anatomic/obstructive changes. If so, gestational pyelonephritis should be caused by random, nonpathogenic bacteria. Instead, gestational pyelonephritis is associated with a narrow group of genetically related Escherichia col...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-002-0041-z
更新日期：2002-12-01 00:00:00
abstract：PURPOSE OF REVIEW:Since the treatment of acute diverticulitis has become more conservative over the last years, knowledge of conservative treatment strategies is increasingly important. RECENT FINDINGS:Several treatment strategies that previously have been imposed as routine treatment are now obsolete. Uncomplicated d...
journal_title：Current infectious disease reports
pub_type： 杂志文章,评审
doi：10.1007/s11908-017-0600-y
更新日期：2017-09-23 00:00:00
abstract：:In the United States each year, influenza accounts for an estimated 20,000 to 40,000 deaths, nearly 300,000 hospitalizations, and millions of days lost from work. In the past few years, there has been an explosion of information in the medical literature related to influenza. This paper reviews these latest developmen...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-000-0039-3
更新日期：2000-06-01 00:00:00
abstract：:Three newer oral antifungal agents, itraconazole, terbinafine and fluconazole, have revolutionized treatment of superficial mycoses. The tissue pharmacokinetics of itraconazole and terbinafine allow much shorter courses of therapy- with higher efficacy-in the treatment of onychomycosis, compared to other oral agents. ...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-000-0074-0
更新日期：2000-10-01 00:00:00
abstract：:Human herpesvirus 8 (HHV-8) or Kaposi's sarcoma (KS)-associated herpesvirus is a recently identified virus that is associated with KS, multicentric Castleman's disease, and body cavity-based lymphomas. KS is the most common kind of cancer in AIDS patients and the initial AIDS-defining condition in over 20% of patients...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-999-0031-5
更新日期：1999-08-01 00:00:00
abstract：:Dermatologic manifestations of travel-related illness are particularly vexing due to the broad differential diagnosis and clinicians' unfamiliarity with uncommonly seen diseases. This paper aims to educate and update the reader on selected infectious diseases in the returned traveler whose disease manifestations are p...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-015-0467-8
更新日期：2015-03-01 00:00:00
abstract：:Acute otitis media (AOM), when associated with a bulging or full tympanic membrane, has a bacterial etiology in more than 90% of cases. Not infrequently, the organisms present express resistance mechanisms to commonly prescribed antibiotic therapy. Tympanocentesis is a procedure advocated by several national guideline...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-006-0058-9
更新日期：2006-05-01 00:00:00
abstract：:The first description of acute respiratory distress syndrome (ARDS) in adults appeared in 1967 and was characterized by dyspnea, hypoxemia, diffuse alveolar infiltrates, and reduced respiratory system compliance. ARDS and acute lung injury (ALI) syndrome have no specific treatment, only supportive care: treating the u...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-009-0052-0
更新日期：2009-09-01 00:00:00
abstract：:Drotrecogin alfa (activated) (DrotAA) has been approved for therapy of severe sepsis and septic shock for 7 years, but controversy persists regarding efficacy and safety. Only a single randomized, controlled trial (Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis; PROWESS) has shown evidence...
journal_title：Current infectious disease reports
pub_type： 杂志文章
doi：10.1007/s11908-008-0060-5
更新日期：2008-09-01 00:00:00
