Abstract:
:Neisseria gonorrhoeae is a common cause of genitourinary sexually transmitted infections. N. gonorrhoeae is an obligate human pathogen that has evidence of tissue-specific host interactions and diverse extragenital manifestations of infection both in adult and pediatric populations. The clinical presentation of extragenital gonorrhea, diagnostic methods, treatment and preventive measures are reviewed.
journal_name
Curr Infect Dis Repjournal_title
Current infectious disease reportsauthors
Spencer SE,Bash MCdoi
10.1007/s11908-006-0009-5keywords:
subject
Has Abstractpub_date
2006-03-01 00:00:00pages
132-8issue
2eissn
1523-3847issn
1534-3146journal_volume
8pub_type
杂志文章abstract::Group A streptococcus is a widespread human pathogen that causes a broad spectrum of human disease. The persistent high burden and severity of illness in developing and industrialized countries speaks to the need for a safe and effective vaccine. Modern approaches to vaccine construction include M protein type-specifi...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-008-0032-9
更新日期:2008-05-01 00:00:00
abstract::Therapy of cryptococcal meningitis has been focused primarily on optimizing the antifungal regimen to improve the previously high treatment failure rates. Until recently, relatively little attention has been paid to the impact of increased intracranial pressure, which is a frequent problem that complicates management ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-002-0026-y
更新日期:2002-08-01 00:00:00
abstract::Neurocysticercosis, caused by infection with the pork tapeworm Taenia solium, is increasingly recognized as a cause of neurologic disease worldwide. Because the clinical presentation is nonspecific, diagnosis has been difficult. Advances in imaging studies and serodiagnostic techniques are facilitating the diagnosis o...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-005-0022-0
更新日期:2005-01-01 00:00:00
abstract::Eosinophilia in patients exposed to tropical or subtropical environments is caused most commonly by helminth (worm) infections. Besides a detailed exposure history, the diagnostic approach must consider other infections and noninfectious causes of eosinophilia, as treatments for many of these disorders differ. ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-006-0034-4
更新日期:2006-01-01 00:00:00
abstract::Although waterborne pathogens are relatively uncommon causes of cutaneous infections, these agents are being recognized with increasing frequency. Humans are exposed to water through a variety of recreational and occupational activities. Poor sanitary conditions in developing nations place the human populations at con...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-003-0020-z
更新日期:2003-10-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to investigate the evolution and epidemiology of Klebsiella pneumoniae carbapenemase (KPC)-producing organisms and the current and future treatment options for infections caused by KPC-producing isolates. RECENT FINDINGS:The emergence of resistance in Enterobacteriaceae ...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-018-0617-x
更新日期:2018-05-05 00:00:00
abstract::Dermatologic manifestations of travel-related illness are particularly vexing due to the broad differential diagnosis and clinicians' unfamiliarity with uncommonly seen diseases. This paper aims to educate and update the reader on selected infectious diseases in the returned traveler whose disease manifestations are p...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-015-0467-8
更新日期:2015-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Suppressive therapy and periodic presumptive treatment (PPT) are distinct but related strategies that have been used to reduce the incidence of bacterial vaginosis (BV). Here, we review clinical trial evidence of the effectiveness of suppressive therapy and PPT to reduce BV, and discuss their roles fo...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-019-0688-3
更新日期:2019-08-31 00:00:00
abstract::Elderly are at high risk for hospitalization for community-acquired pneumonia (CAP), especially due to Streptococcus pneumoniae, and seasonal influenza viruses. Data suggest PPV23's influence on various CAP-related outcomes among the elderly may depend upon how many years have elapsed since they received this vaccine....
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-015-0505-6
更新日期:2015-12-01 00:00:00
abstract::Urinary tract infection (UTI) is a common clinical syndrome in women. Most UTIs are caused by Escherichia coli. UTI has become a productive and accessible model system for studying the molecular details of how bacteria interact with mucosal surfaces and the nature of the host response. Important advances in the past y...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-006-0021-9
更新日期:2006-11-01 00:00:00
abstract:PURPOSE OF REVIEW:The increase in drug-resistant community-acquired pneumonia (CAP) is an important problem all over the world. This article explores the current state of antimicrobial resistance of different bacteria that cause CAP and also assesses risk factors to identify those pathogens. RECENT FINDINGS:In the las...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0565-x
更新日期:2017-03-01 00:00:00
abstract::In recent years, substantial advances have been achieved in the treatment of mucormycosis. It is now clear that early initiation of therapy results in substantially better outcomes, underscoring the need to maintain a high index of suspicion and aggressively biopsy potential lesions. Increasing data support the need f...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0129-9
更新日期:2010-11-01 00:00:00
abstract::Healthcare-associated bacterial meningitis may occur after neurosurgical procedures, head trauma, and following placement of external or internal ventricular catheters. The likely microorganisms that cause meningitis in this setting (ie, staphylococci and gram-negative bacilli) are different from those that cause meni...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-011-0190-z
更新日期:2011-08-01 00:00:00
abstract:PURPOSE OF REVIEW:The infectious complications of transplantation can have devastating consequences for patients. Early and accurate diagnosis is essential to good outcomes. This review describes recent advances in pathogen-directed diagnostic testing and discusses the role of new methods for transplant infectious dise...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-019-0704-7
更新日期:2019-11-26 00:00:00
abstract::In most high-income countries, fewer children now acquire meningitis, and many of those who do will survive. Globally, however, meningitis still remains a significant cause of child morbidity and mortality. In this article, the authors review recent evidence on the morbidity faced by childhood survivors of bacterial m...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-013-0332-6
更新日期:2013-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Modern advances in malaria rapid diagnostic test (RDT) technology have increased demand for low-cost, easy-to-use assays in areas endemic for malaria. Substantial developments in diagnostic sensitivity and specificity, improvements in non-falciparum RDTs, and novel biotechnological innovations are gra...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-018-0655-4
更新日期:2018-10-23 00:00:00
abstract::In an era of cost-consciousness in the delivery of medical care, the economics of healthcare delivery for HIV-infected persons has been an area of active interest. Interested parties include the payors of HIV care, particularly public insurers, who are paying for an increasing amount of the overall cost of HIV care in...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-000-0018-8
更新日期:2000-08-01 00:00:00
abstract::Reduction of microbial contamination of the hospital environment is a challenge, yet has potential impacts on infection prevention efforts. Fumigation and UV light devices for environmental cleaning have expanded into the health care setting with the goal of decontamination of difficult to clean or overlooked surfaces...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-015-0498-1
更新日期:2015-09-01 00:00:00
abstract::Bacterial meningitis remains a feared diagnosis that may lead to significant mortality and morbidity in both the developed and developing world; case fatality rates range from 10% to 50% among all age groups. Several vaccines are available (including the Haemophilus influenzae type B polysaccharide conjugate vaccine) ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-009-0045-z
更新日期:2009-07-01 00:00:00
abstract::Determining the microbiologic etiology of enteric infection remains an elusive goal. Conventional approaches, including culture, microscopy, and antigen-based tests have significant limitations such as limit of detection and the need for multiple procedures. Molecular diagnostics, especially PCR based tests, are rapid...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-011-0223-7
更新日期:2012-02-01 00:00:00
abstract::Rates of syphilis continue to increase in the United States and HIV-infected patients make up a large proportion of cases. The interaction between syphilis and HIV is complex and still incompletely understood. Although diagnosis and management of HIV-infected patients with syphilis is, in general, similar to HIV-uninf...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0083-6
更新日期:2010-03-01 00:00:00
abstract::Pouchitis is an inflammatory complication after restorative proctocolectomy and ileal pouch-anal anastomosis (IPAA). IPAA is the surgical treatment of choice in patients with ulcerative colitis (UC) who require colectomy. Initial episodes of acute pouchitis generally respond to antibiotics but significant numbers of c...
journal_title:Current infectious disease reports
pub_type: 杂志文章
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更新日期:2014-12-01 00:00:00
abstract::Necrotizing enterocolitis (NEC) continues to be a major cause of morbidity and mortality in premature infants. Although the pathogenesis of NEC remains unclear, abnormal bacterial colonization has been postulated as playing a central role. Various factors impact bacterial colonization following delivery. Compared to t...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0156-6
更新日期:2011-02-01 00:00:00
abstract::Infections due to community-associated methicillin---resistant Staphylococcus aureus (CA-MRSA) are becoming more prevalent. CA-MRSA infections have unique epidemiologic features and virulence factors. Compared with health care-associated MRSA (HA-MRSA), most CA-MRSA is clonal type USA300 or 400 and has the Staphylococ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-008-0005-z
更新日期:2008-03-01 00:00:00
abstract::Urinary tract infections are common, especially among women, and cause significant morbidity. While prognosis is probably more dependent on whether or not an episode of urinary tract infection is complicated (ie, associated with functional, metabolic, or anatomic abnormalities of the urinary tract) or uncomplicated, a...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-001-0090-8
更新日期:2001-12-01 00:00:00
abstract::The possibility that infection with Chlamydia pneumoniae may somehow contribute to the pathogenesis of atherosclerosis continues to be explored by researchers worldwide. A direct cause-and-effect relationship between the bacterium and subsequent development of atherosclerosis has yet to be proved. However, compelling ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-996-0021-9
更新日期:1999-06-01 00:00:00
abstract::Clostridium difficile is a major cause of antibiotic-associated diarrhea. While treatment regimens for C. difficile have been available for decades, they remain less than optimal due to the frequent recurrences that occur after therapy is completed. Moreover, the morbidity and expense associated with C. difficile have...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-996-0032-6
更新日期:2001-04-01 00:00:00
abstract::Ventilator-associated pneumonia (VAP), an infection of the lower respiratory tract which occurs in association with mechanical ventilation, is one of the most common causes of nosocomial infection in the intensive care unit (ICU). VAP causes significant morbidity and mortality in critically ill patients including incr...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-015-0496-3
更新日期:2015-08-01 00:00:00
abstract::Human herpesvirus 8 (HHV-8) or Kaposi's sarcoma (KS)-associated herpesvirus is a recently identified virus that is associated with KS, multicentric Castleman's disease, and body cavity-based lymphomas. KS is the most common kind of cancer in AIDS patients and the initial AIDS-defining condition in over 20% of patients...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-999-0031-5
更新日期:1999-08-01 00:00:00
abstract::Africa carries a disproportionate burden of the global HIV endemic, accounting for two thirds of the global 33.3 million people living with HIV. While tremendous advances have been made in addressing the HIV epidemic in Africa, considerable challenges remain. Testing for HIV increased by 86% from 2007 to 2009 but more...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-011-0230-8
更新日期:2012-02-01 00:00:00