Abstract:
:Rates of syphilis continue to increase in the United States and HIV-infected patients make up a large proportion of cases. The interaction between syphilis and HIV is complex and still incompletely understood. Although diagnosis and management of HIV-infected patients with syphilis is, in general, similar to HIV-uninfected patients, the former may be at increased risk for complications. Recent data suggest that HIV-induced immunosuppression may alter the course of syphilis and that highly active antiretroviral therapy may have a beneficial effect on syphilis outcomes. Prevention strategies consisting of sexual risk assessments, condom use, treatment of infected partners, yearly screening for syphilis of all HIV-infected patients, and enhanced clinical and serologic follow-up of treated HIV-infected patients are critical components of a comprehensive approach to care.
journal_name
Curr Infect Dis Repjournal_title
Current infectious disease reportsauthors
Ghanem KGdoi
10.1007/s11908-010-0083-6subject
Has Abstractpub_date
2010-03-01 00:00:00pages
140-6issue
2eissn
1523-3847issn
1534-3146journal_volume
12pub_type
杂志文章abstract::Pulmonary nocardiosis is an uncommon but serious infection that is increasingly found in immunosuppressed persons, especially transplant recipients and persons with AIDS. The Nocardia species are denizens of soil and decaying plants that gain entry to humans through inhalation or inoculation. Pulmonary nocardiosis typ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-001-0032-5
更新日期:2001-06-01 00:00:00
abstract::Although waterborne pathogens are relatively uncommon causes of cutaneous infections, these agents are being recognized with increasing frequency. Humans are exposed to water through a variety of recreational and occupational activities. Poor sanitary conditions in developing nations place the human populations at con...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-003-0020-z
更新日期:2003-10-01 00:00:00
abstract::Skin lesions provide an important clue to the diagnoses of many infections in returned travelers. New information related to epidemiology, recognition, diagnosis, or management is described for the systemic infections--dengue fever, several of the rickettsial infections, African trypanosomiasis, and coccidioidomycosis...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-004-0025-2
更新日期:2004-02-01 00:00:00
abstract::Urinary tract infection (UTI) is common in postmenopausal women; the estimated incidence ranges from 4% to 15%. The clinical presentation of UTI is somewhat different in postmenopausal older women than it is in younger women: postmenopausal women are less likely to report frequency, dysuria, hematuria, and fever, but ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-999-0043-1
更新日期:1999-10-01 00:00:00
abstract::All of the endemic mycoses have cutaneous and mucocutaneous manifestations that are most commonly seen when patients have disseminated infection. Biopsy of skin lesions is simple and safe and can assist in making a timely diagnosis of disseminated infection. Primary cutaneous inoculation infection has been reported wi...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-013-0352-2
更新日期:2013-10-01 00:00:00
abstract::Eosinophilia in patients exposed to tropical or subtropical environments is caused most commonly by helminth (worm) infections. Besides a detailed exposure history, the diagnostic approach must consider other infections and noninfectious causes of eosinophilia, as treatments for many of these disorders differ. ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-006-0034-4
更新日期:2006-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to investigate the evolution and epidemiology of Klebsiella pneumoniae carbapenemase (KPC)-producing organisms and the current and future treatment options for infections caused by KPC-producing isolates. RECENT FINDINGS:The emergence of resistance in Enterobacteriaceae ...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-018-0617-x
更新日期:2018-05-05 00:00:00
abstract::Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. Patients with COPD are at increased risk for community-acquired pneumonia (CAP). COPD has been reported as a comorbidity in at least one third of the hospitalized patients with CAP. There is a controversy that the pre...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-014-0444-7
更新日期:2015-01-01 00:00:00
abstract::In the United States each year, influenza accounts for an estimated 20,000 to 40,000 deaths, nearly 300,000 hospitalizations, and millions of days lost from work. In the past few years, there has been an explosion of information in the medical literature related to influenza. This paper reviews these latest developmen...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-000-0039-3
更新日期:2000-06-01 00:00:00
abstract::Bacterial meningitis is a complex disorder in which neurologic injury is caused, in part, by the causative organism and, in part, by the host's own inflammatory response. In studies of experimental bacterial meningitis, adjuvant treatment with corticosteroids, specifically dexamethasone, has beneficial effects. On the...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-005-0061-6
更新日期:2005-07-01 00:00:00
abstract::Lower respiratory tract infections (LRTIs) are a global burden to public health and are frequently caused by respiratory viruses. Advances in molecular diagnostic techniques have allowed the identification of previously undetected viral pathogens and have improved our understanding of respiratory virus infections. Her...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-012-0258-4
更新日期:2012-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Post-transplant infections present a formidable challenge to the physician due to their varied presentation. Many of these infections begin by inoculation following skin compromise or disseminate to the skin hematogenously, making cutaneous manifestations of infection an important diagnostic clue in t...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-018-0621-1
更新日期:2018-05-22 00:00:00
abstract::The ability to predict efficacy and toxicity during antiretroviral therapy for HIV would be of obvious advantage. The substantial variability between patients in terms of bioavailability and distribution of current regimens is likely driven by genetic and environmental factors. Protease inhibitors and nucleoside/nucle...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-006-0052-2
更新日期:2006-09-01 00:00:00
abstract::The 2009 pandemic influenza A (H1N1) was responsible for the first influenza pandemic of the 21st century. The virus- a previously unknown triple-reassortant virus containing segments of avian, human, and swine origins- generally caused mild disease. Unlike seasonal influenza, 2009 pandemic influenza A (H1N1) primaril...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0157-5
更新日期:2011-04-01 00:00:00
abstract::Drotrecogin alfa (activated) (DrotAA) has been approved for therapy of severe sepsis and septic shock for 7 years, but controversy persists regarding efficacy and safety. Only a single randomized, controlled trial (Recombinant Human Activated Protein C Worldwide Evaluation in Severe Sepsis; PROWESS) has shown evidence...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-008-0060-5
更新日期:2008-09-01 00:00:00
abstract::Infectious myositis is defined as an infection of a skeletal muscle. Infectious myositis is most commonly caused by bacteria; however, a variety of viral, parasitic, and fungal agents may also cause myositis. The pathogenesis of nonbacterial infectious myositis is via direct or hematogenous infection of the musculatur...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0118-z
更新日期:2010-09-01 00:00:00
abstract::There is strong evidence that preoperative nasal S. aureus screening/decolonization will significantly reduce surgical site infections (SSIs) after joint prostheses implantation. There is some evidence that antibiotic-containing bone cement may lower SSI rates. Timely administration of perioperative systemic antibioti...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-012-0278-0
更新日期:2012-10-01 00:00:00
abstract::A variety of antigen-capture assays are commercially available for the detection of influenza. In addition, real-time multiplex polymerase chain reaction (PCR) has been used to detect influenza A and B in clinical specimens. The commercial assays can be completed in less than 30 minutes and have a sensitivity of at le...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-005-0033-x
更新日期:2005-05-01 00:00:00
abstract::Candida species remain the most frequently isolated fungi in intensive care unit (ICU) patients with severe sepsis or septic shock. Delayed antifungal therapy in these patients is a recognized risk factor for mortality. However, the diagnosis of invasive candidiasis remains difficult and is frequently delayed. Clinica...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-011-0204-x
更新日期:2011-10-01 00:00:00
abstract::Africa carries a disproportionate burden of the global HIV endemic, accounting for two thirds of the global 33.3 million people living with HIV. While tremendous advances have been made in addressing the HIV epidemic in Africa, considerable challenges remain. Testing for HIV increased by 86% from 2007 to 2009 but more...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-011-0230-8
更新日期:2012-02-01 00:00:00
abstract::Contact precautions are routinely employed for the control of multidrug-resistant organisms. Robust measures, however, for the incremental benefit of contact precautions, gowns, gloves, and active detection and isolation strategies for the prevention of cross-transmission in endemic settings are lacking. Unintended co...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-012-0299-8
更新日期:2012-12-01 00:00:00
abstract::Colonization with Staphylococcus aureus is a risk factor for invasive S. aureus infections. Intranasal mupirocin has effectively eradicated S. aureus colonization and appears to prevent S. aureus nosocomial infections in some patient populations. In hospitals and communities where mupirocin use has been widespread, re...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-004-0062-x
更新日期:2004-12-01 00:00:00
abstract::Treatment of chronic rhinosinusitis still represents an unmet medical need. Presently, the US Food and Drug Administration has not approved any drugs for the treatment of this common condition. Various inflammatory processes are involved in the pathogenesis of chronic rhinosinusitis. Treatment of infection and surgica...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-007-0031-2
更新日期:2007-05-01 00:00:00
abstract::Diarrhea is one of the most common health problems among travelers. Although enterotoxigenic Escherichia coli is implicated most commonly, enteroaggregative E. coli has recently been described as a major pathogen. Shigella, Campylobacter, and Salmonella organisms are less common causes of acute diarrhea, and intestina...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-002-0070-7
更新日期:2002-02-01 00:00:00
abstract::Necrotizing enterocolitis (NEC) continues to be a major cause of morbidity and mortality in premature infants. Although the pathogenesis of NEC remains unclear, abnormal bacterial colonization has been postulated as playing a central role. Various factors impact bacterial colonization following delivery. Compared to t...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0156-6
更新日期:2011-02-01 00:00:00
abstract::Bacterial meningitis remains a feared diagnosis that may lead to significant mortality and morbidity in both the developed and developing world; case fatality rates range from 10% to 50% among all age groups. Several vaccines are available (including the Haemophilus influenzae type B polysaccharide conjugate vaccine) ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-009-0045-z
更新日期:2009-07-01 00:00:00
abstract::Prosthetic valve endocarditis (PVE) due to mycobacteria is a rare but frequently fatal complication that may occur early after the surgical procedure, or even years later. Infection has been described with both mechanical and biologic valvular prosthesis. The most commonly implicated mycobacterial species belong to th...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-010-0108-1
更新日期:2010-07-01 00:00:00
abstract::The possibility that infection with Chlamydia pneumoniae may somehow contribute to the pathogenesis of atherosclerosis continues to be explored by researchers worldwide. A direct cause-and-effect relationship between the bacterium and subsequent development of atherosclerosis has yet to be proved. However, compelling ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-996-0021-9
更新日期:1999-06-01 00:00:00
abstract:PURPOSE OF REVIEW:Community-acquired pneumonia (CAP) is the cause of a considerable burden of morbidity and mortality among HIV-infected patients. The purpose of this study was to review recent literature for epidemiological trends and management of CAP in HIV patients. RECENT FINDINGS:While the specific infectious et...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0559-8
更新日期:2017-01-01 00:00:00
abstract::Heavily pretreated HIV-infected patients with multidrug-resistant virus remain a clinical challenge to the treating physician. While the goal of therapy in such patients is still controversial, sustained immunologic and clinical benefit have only been demonstrated with complete suppression of plasma viral load below d...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-002-0089-9
更新日期:2002-06-01 00:00:00