Abstract:
:A variety of antigen-capture assays are commercially available for the detection of influenza. In addition, real-time multiplex polymerase chain reaction (PCR) has been used to detect influenza A and B in clinical specimens. The commercial assays can be completed in less than 30 minutes and have a sensitivity of at least 70% and a specificity of 90%, compared with viral isolation. They are useful not only in the diagnosis and treatment of individual patients with influenza-like illness but also in surveillance for influenza, decreasing the time of nosocomial outbreaks, decreasing the use of laboratory tests, and decreasing antibiotic use in patients with influenza. Some of the rapid antigen assays, and PCR, can detect the H5N1 and H9N1 viruses. Real-time multiplex PCR also detects a variety of respiratory viruses within 6 hours, with only 1 hour of hands-on technician time. The widespread use of the rapid tests for influenza is changing the practice pattern of physicians who care for patients with influenza.
journal_name
Curr Infect Dis Repjournal_title
Current infectious disease reportsauthors
Pachucki CTdoi
10.1007/s11908-005-0033-xkeywords:
subject
Has Abstractpub_date
2005-05-01 00:00:00pages
187-192issue
3eissn
1523-3847issn
1534-3146journal_volume
7pub_type
杂志文章abstract::Primary infection of humans with varicella zoster virus (VZV) causes varicella (chickenpox), after which the virus becomes latent in cranial nerve ganglia, dorsal root ganglia and autonomic ganglia along the entire neuraxis. As VZV-specific cell-mediated immunity declines in elderly and immunocompromised individuals, ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-014-0407-z
更新日期:2014-06-01 00:00:00
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journal_title:Current infectious disease reports
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doi:10.1007/s11908-010-0157-5
更新日期:2011-04-01 00:00:00
abstract::Before the advent of antiretroviral therapy (ART), CMV retinitis was a common, debilitating opportunistic infection in the HIV-infected population. ART has had such a favorable impact on the prevention and management of CMV retinitis that it can be considered in some ways to be CMV therapy. Currently available CMV dir...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-012-0269-1
更新日期:2012-08-01 00:00:00
abstract:PURPOSE OF REVIEW:This review attempts to understand the reasons for the successes and failures of the two novel strategies that have slowly begun to emerge as potential counters for anti-malarial drug resistance-"Triple Combination Therapy" and "Drug Cycling." RECENT FINDINGS:Recent reports have suggested that increa...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0579-4
更新日期:2017-07-01 00:00:00
abstract::Clinical toxinology is a specialized area of clinical medicine focused on the pathophysiology, diagnosis, treatment, and prevention of diseases caused by animal, plant, and fungal toxins. This review focuses on recent developments in snakebite. Snakebite is newly recognized as a Neglected Tropical Disease by the World...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-011-0172-1
更新日期:2011-06-01 00:00:00
abstract:PURPOSE OF THE REVIEW:Community-acquired pneumonia (CAP) is still associated with a large burden and causes significant morbidity and mortality. Besides universal vaccination and antibiotic treatment, statins as adjunctive therapy may also have a beneficial role in the prevention and treatment of CAP. Our goal from thi...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0581-x
更新日期:2017-08-01 00:00:00
abstract::Neurocysticercosis, caused by infection with the pork tapeworm Taenia solium, is increasingly recognized as a cause of neurologic disease worldwide. Because the clinical presentation is nonspecific, diagnosis has been difficult. Advances in imaging studies and serodiagnostic techniques are facilitating the diagnosis o...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-005-0022-0
更新日期:2005-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this article is to perform a systematic review over the past 5 years on the role and effectiveness of clinical decision support systems (CDSSs) on antibiotic stewardship. RECENT FINDINGS:CDDS interventions found a significant impact on multiple outcomes relevant to antibiotic stewardsh...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-019-0683-8
更新日期:2019-07-24 00:00:00
abstract::In an era of cost-consciousness in the delivery of medical care, the economics of healthcare delivery for HIV-infected persons has been an area of active interest. Interested parties include the payors of HIV care, particularly public insurers, who are paying for an increasing amount of the overall cost of HIV care in...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-000-0018-8
更新日期:2000-08-01 00:00:00
abstract:PURPOSE OF REVIEW:The infectious complications of transplantation can have devastating consequences for patients. Early and accurate diagnosis is essential to good outcomes. This review describes recent advances in pathogen-directed diagnostic testing and discusses the role of new methods for transplant infectious dise...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-019-0704-7
更新日期:2019-11-26 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-005-0007-z
更新日期:2005-09-01 00:00:00
abstract::Streptococcus bovis is a rare, but important cause of bacterial meningitis in children. Since its discovery in the early 1970s, the pathogen has undergone multiple taxonomic changes producing four distinct subspecies today, the most prevalent of which is S. gallolyticus subsp pasteurianus in infants and children. Whil...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-016-0519-8
更新日期:2016-03-01 00:00:00
abstract::The immune reconstitution inflammatory syndrome (IRIS) is a well-described phenomenon in HIV-infected patients following initiation of antiretroviral therapy and can lead to significant morbidity and mortality in some patients. Risk for IRIS is enhanced in those with low CD4 counts and preexisting opportunistic infect...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-012-0308-y
更新日期:2013-02-01 00:00:00
abstract::Three newer oral antifungal agents, itraconazole, terbinafine and fluconazole, have revolutionized treatment of superficial mycoses. The tissue pharmacokinetics of itraconazole and terbinafine allow much shorter courses of therapy- with higher efficacy-in the treatment of onychomycosis, compared to other oral agents. ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-000-0074-0
更新日期:2000-10-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this paper is to review therapies with new mechanisms of action for the treatment of HIV that are at least in phase 2 clinical trials. RECENT FINDINGS:There are several new mechanisms of action being represented within clinical development, including histone deacetylase (HDAC) inhibito...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-017-0601-x
更新日期:2017-09-19 00:00:00
abstract::Reduction of microbial contamination of the hospital environment is a challenge, yet has potential impacts on infection prevention efforts. Fumigation and UV light devices for environmental cleaning have expanded into the health care setting with the goal of decontamination of difficult to clean or overlooked surfaces...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-015-0498-1
更新日期:2015-09-01 00:00:00
abstract::Rotaviruses are the most important cause of pediatric gastroenteritis worldwide. In August 1998, a new rotavirus vaccine was licensed for general use in the United States. However, 14 months later, the vaccine was withdrawn from the market because of serious gastrointestinal side effects. This paper discusses the need...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-000-0090-0
更新日期:2000-02-01 00:00:00
abstract::Colonization with Staphylococcus aureus is a risk factor for invasive S. aureus infections. Intranasal mupirocin has effectively eradicated S. aureus colonization and appears to prevent S. aureus nosocomial infections in some patient populations. In hospitals and communities where mupirocin use has been widespread, re...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-004-0062-x
更新日期:2004-12-01 00:00:00
abstract::Bacterial meningitis is a complex disorder in which neurologic injury is caused, in part, by the causative organism and, in part, by the host's own inflammatory response. In studies of experimental bacterial meningitis, adjuvant treatment with corticosteroids, specifically dexamethasone, has beneficial effects. On the...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-005-0061-6
更新日期:2005-07-01 00:00:00
abstract::Endocarditis pathogens colonize valves with pre-existing sterile vegetations or valves with minimal endothelial lesions. Inflamed endothelia produce cytokines, integrins, and tissue factor, which in turn attract fibronectin, monocytes, and platelets. Bacteria attaching to such structures further activate the cascade, ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-006-0071-z
更新日期:2006-06-01 00:00:00
abstract::Starting from 2010, the 13-valent pneumococcal conjugate vaccine (PCV13) was introduced in several countries. This paper discusses some of the problems recently emerged after PCV13 use and their clinical impact. The impact of PCV13 has been relevant and has saved millions of children and adults by severe infectious di...
journal_title:Current infectious disease reports
pub_type: 杂志文章,评审
doi:10.1007/s11908-018-0607-z
更新日期:2018-01-24 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-011-0175-y
更新日期:2011-06-01 00:00:00
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journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-003-0064-0
更新日期:2003-02-01 00:00:00
abstract::The pathogenesis of vulvovaginal candidiasis, which is caused by Candida albicans, is poorly understood. Despite a strong protective role for cell-mediated immunity (CMI) against other mucosal candidal infections, numerous studies in humans and most animal models have revealed little to no role for CMI or other forms ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-003-0092-9
更新日期:2003-12-01 00:00:00
abstract::The outcome for HIV-infected patients with cancer has dramatically improved in the highly active antiretroviral therapy (HAART) era, probably due to improvements in immune status and bone marrow function that allow the possibility of increased drug-dose intensity with a higher complete remission rate. Although data re...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-008-0026-7
更新日期:2008-05-01 00:00:00
abstract::Cyclosporiasis is a food- and water-borne infection that affects healthy and immunocompromised individuals. Awareness of the disease has increased, and outbreaks continue to be reported among vulnerable hosts and now among local residents in endemic areas. Advances in molecular techniques have improved identification ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-009-0016-4
更新日期:2009-03-01 00:00:00
abstract::Arthroplasty of the knee and hip is a common procedure. There is a risk of infection with primary arthroplasty, with an incidence of 1% to 2%. Significant cost and morbidity are associated with infection of the prosthetic joint. Most infections (60% to 70%) are caused by staphylococci, but approximately 10% are caused...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-004-0038-x
更新日期:2004-10-01 00:00:00
abstract::About 1% of all patients with end-stage renal disease in the United States are infected with HIV. With the introduction of highly active antiretroviral therapy (HAART), HIV death rates have declined 80%, and chronic diseases resulting from HIV have replaced opportunistic infections as the leading cause of death among ...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-009-0078-3
更新日期:2010-01-01 00:00:00
abstract::Skin lesions provide an important clue to the diagnoses of many infections in returned travelers. New information related to epidemiology, recognition, diagnosis, or management is described for the systemic infections--dengue fever, several of the rickettsial infections, African trypanosomiasis, and coccidioidomycosis...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-004-0025-2
更新日期:2004-02-01 00:00:00
abstract::Urinary tract infection (UTI) is a common clinical syndrome in women. Most UTIs are caused by Escherichia coli. UTI has become a productive and accessible model system for studying the molecular details of how bacteria interact with mucosal surfaces and the nature of the host response. Important advances in the past y...
journal_title:Current infectious disease reports
pub_type: 杂志文章
doi:10.1007/s11908-006-0021-9
更新日期:2006-11-01 00:00:00