Reducing agent and tunicamycin-responsive protein (RTP) mRNA expression in the placentae of normal and pre-eclamptic women.

abstract：BACKGROUND/PURPOSE:Human placenta and chorion are rapidly growing transient embryonic organs built from diverse cell populations that are of either, ectodermal [placenta and chorion specific trophoblast (TB) cells], or mesodermal origin [villous core and chorionic mesenchyme]. The development of placenta and chorion is...

journal_title：Placenta

authors： Genbačev O,Vićovac L,Larocque N

更新日期：2015-07-01 00:00:00

abstract：:Growth characteristics and the expression of trophoblast-associated markers by six cell lines generated from midgestation chorioallantoic placentas of outbred (Holtzman) and inbred (Lewis, PVG.RT Ir8) rats were evaluated. The cells comprising all cell lines were epithelioid (contained cytokeratin-type intermediate fil...

journal_title：Placenta

authors： Hunt JS,Deb S,Faria TN,Wheaton D,Soares MJ

更新日期：1989-03-01 00:00:00

abstract：:Previous studies have shown that human and mouse placentas have hematopoietic potential during mid-gestation. In this investigation, we used histological and immunohistological approaches to visualize hematopoietic cells in mouse placenta between 9.5 and 12.5 days of gestation (gd), identifying their topography and ni...

journal_title：Placenta

authors： Azevedo Portilho N,Tavares Guedes P,Croy BA,Pelajo-Machado M

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Scant data on placental lymphatic vessels have pointed to the absence of lymphatic circulation. A recent study on mesenchymal dysplasia (MD), however, has identified pathologic lymphangiogenesis using the D2-40 lymphatic marker. These conflicting data have prompted us to investigate whether lymphatic vessels...

journal_title：Placenta

authors： Castro E,Tony Parks W,Galambos C

更新日期：2011-04-01 00:00:00

abstract：:Pregnancy-specific beta 1-glycoprotein (Schwangerschaftsprotein, SP1) is elevated in the amniotic fluid in Meckel's syndrome. In an attempt to clarify this phenomenon, we studied fetal tissues by immunohistochemistry for the distribution of SP1 in normal fetuses and fetuses with Meckel's syndrome. The amount of SP1 wa...

journal_title：Placenta

authors： Heikinheimo M,Jalanko H,Renlund M,Rapola J,Wahlström T

更新日期：1987-07-01 00:00:00

abstract：:TRH immunological and biological activity was characterized in rat placental extracts. Placentae were extracted sequentially with 2 N acetic acid and glacial acetic acid. The lyophilized residues were further extracted with 90 per cent methanol, and the extracts were then dried, and reextracted with distilled water. W...

journal_title：Placenta

authors： Shambaugh GE 3rd,Kubek M,Wilber JF

更新日期：1983-10-01 00:00:00

abstract：:Neutral endopeptidase 24.11 (NEP) is known to regulate cellular functions by degrading several bioactive peptides, such as gonadotropin-releasing hormone (GnRH). The present study was performed to clarify the mechanisms of NEP expression by GnRH in human choriocarcinoma (BeWo) cells. GnRH increased NEP expression and ...

journal_title：Placenta

authors： Kikkawa F,Shibata K,Suzuki T,Kajiyama H,Ino K,Nomura S,Mizutani S

更新日期：2004-02-01 00:00:00

abstract：:Placental stem cells are of growing interest for a variety of clinical applications due to their multipotency and ready availability from otherwise frequently discarded biomaterial. Stem cells derived from the placenta have been investigated in a number of disease processes, including wound healing, ischemic heart dis...

journal_title：Placenta

authors： Vanover M,Wang A,Farmer D

更新日期：2017-11-01 00:00:00

abstract：:The EAT/mcl-1 gene was isolated during the early differentiation of a retinoic acid-induced human embryonal carcinoma cell line to the trophectoderm lineage. EAT/mcl-1, a bcl-2 related gene, is involved in the genetic pathway of apoptosis; this suggests a role for apoptosis and the involvement of this gene in early pl...

journal_title：Placenta

authors： Suzuki A,Umezawa A,Sano M,Nozawa S,Hata J

更新日期：2000-03-01 00:00:00

abstract：:Human endothelial dysfunction is a common feature in many diseases of pregnancy, such as gestational diabetes (GD). Metabolic changes include abnormal synthesis of nitric oxide (NO) and abnormal membrane transport of l-arginine and adenosine in primary cultures of human umbilical vein (HUVEC, macrovascular) and placen...

journal_title：Placenta

authors： Sobrevia L,Abarzúa F,Nien JK,Salomón C,Westermeier F,Puebla C,Cifuentes F,Guzmán-Gutiérrez E,Leiva A,Casanello P

更新日期：2011-03-01 00:00:00

abstract：:When cultured in keratinocyte growth medium, mononuclear cytotrophoblast cells aggregate into multicellular colonies which then fuse to form multinucleated syncytiotrophoblast. In an attempt to characterize better the mechanism of human trophoblast differentiation and to obtain information about the role of the cytosk...

journal_title：Placenta

authors： Douglas GC,King BF

更新日期：1993-03-01 00:00:00

abstract：:Breast Cancer Resistance Protein (BCRP), a recently-discovered transporter belonging to ABC superfamily, is highly expressed within the labyrinth of the placenta, the primary site of exchange between the maternal and fetal circulation. It has been proposed to function as an efflux pump protecting the fetus from a wide...

journal_title：Placenta

authors： Kalabis GM,Petropoulos S,Gibb W,Matthews SG

更新日期：2007-10-01 00:00:00

abstract：:Early placental development is characterised by rapid cell differentiation and migration, matrix remodelling and angiogenesis. The enzyme NAD(P)H oxidase is a major source of superoxide anions implicated in signalling pathways regulating these processes in other systems. It is also thought to be involved in oxygen sen...

journal_title：Placenta

authors： Raijmakers MT,Burton GJ,Jauniaux E,Seed PT,Peters WH,Steegers EA,Poston L

更新日期：2006-02-01 00:00:00

abstract：:Dietary taurine is essential for cats and deficiency during pregnancy may lead to abortion, growth restriction or impaired neurological function of kittens. We previously described Na(+)- and Cl(-)-dependent taurine transport by system beta in fragments of freshly isolated cat placenta [Champion EE, Bailey SJ, Glazier...

journal_title：Placenta

authors： Champion EE,Mann SJ,Glazier JD,Jones CJ,Rawlings JM,Sibley CP,Greenwood SL

更新日期：2005-09-01 00:00:00

abstract：:Confocal and conventional indirect immunofluorescence and immunogold electron microscopic methods were applied to examine the distribution of extracellular matrix constituents (collagens types III and IV) in the villi of immature and term human placentae. The immunofluorescence study revealed that collagen type III is...

journal_title：Placenta

authors： Nanaev AK,Rukosuev VS,Shirinsky VP,Milovanov AP,Domogatsky SP,Duance VC,Bradbury FM,Yarrow P,Gardiner L,d'Lacey C

更新日期：1991-11-01 00:00:00

abstract：INTRODUCTION:Perfluorinated alkyl acids (PFAAs) are widely used in industry and consumer products. Pregnant women are exposed to PFAAs and their presence in umbilical cord blood represents fetal exposure. Interestingly, PFAAs are substrates for organic anion transporters (OAT) of which OAT4 is expressed in human placen...

journal_title：Placenta

authors： Kummu M,Sieppi E,Koponen J,Laatio L,Vähäkangas K,Kiviranta H,Rautio A,Myllynen P

更新日期：2015-10-01 00:00:00

abstract：:Human placental villi are surfaced by an outer multinucleated syncytiotrophoblast and underlying mononucleated cytotrophoblasts. Conflicting data have attributed one, or the other, of these villous trophoblast phenotypes to undergo enhanced apoptosis in complicated pregnancies, compared to term, normotensive pregnanci...

journal_title：Placenta

authors： Longtine MS,Chen B,Odibo AO,Zhong Y,Nelson DM

更新日期：2012-05-01 00:00:00

abstract：:Maternal and fetal cellular relationships in the normal human term placental basal plate were investigated by single and double immunohistochemical labelling techniques. Extravillous fetal trophoblast in the basal plate was uniformly reactive with markers of low-molecular-weight cytokeratins. The predominant maternal ...

journal_title：Placenta

authors： Bulmer JN,Smith J,Morrison L,Wells M

更新日期：1988-05-01 00:00:00

abstract：:The morphometric oxygen diffusive conductance (D(p)) of the placenta provides a measure of the efficiency of oxygen transfer between the mother and the developing fetus. Any change in the D(p)may point towards possible adaptation in the light of altered oxygen transfer. Placentae from normal (n=40) and small for gesta...

journal_title：Placenta

authors： Ansari T,Fenlon S,Pasha S,O'Neill B,Gillan JE,Green CJ,Sibbons PD

更新日期：2003-07-01 00:00:00

abstract：:Hyperplastic placentas have been reported in several experimental mouse models, including animals produced by somatic cell nuclear transfer, by inter(sub)species hybridization, and by somatic cytoplasm introduction to oocytes followed by intracytoplasmic sperm injection. Of great interest are the gross and histologica...

journal_title：Placenta

authors： Wakisaka N,Inoue K,Ogonuki N,Miki H,Sekita Y,Hanaki K,Akatsuka A,Kaneko-Ishino T,Ishino F,Ogura A

更新日期：2008-08-01 00:00:00

abstract：:Placenta accreta is a pregnancy complication characterized by the presence of life-threatening uteroplacental neovascularization. The factors involving its development are unknown. Vascular endothelial growth factor (VEGF), placenta growth factor (PlGF) and their receptors (VEGFR) have important roles in vascular remo...

journal_title：Placenta

authors： Tseng JJ,Chou MM,Hsieh YT,Wen MC,Ho ES,Hsu SL

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:The interaction between trophoblast cells and maternal uterine endothelium is important for placental vascular modelling. Nitric oxide (NO) is a potent vasorelaxant that regulates systemic blood pressure and is reduced in preeclampsia. NO may affect placental cell interaction. OBJECTIVES:This study was to...

journal_title：Placenta

authors： Xu B,Charlton F,Makris A,Hennessy A

更新日期：2014-06-01 00:00:00

abstract：:Placental malaria (PM) causes placental insufficiency, leading to reduced birth weight (BW). Placental mtDNA copy number (mtDNA-CN) and relative telomere length (RTL) have been described as potential biomarkers for placental insufficiency and intrauterine growth restriction (IUGR). We investigated their associations w...

journal_title：Placenta

authors： Oktavianthi S,Fauzi M,Trianty L,Trimarsanto H,Bowolaksono A,Noviyanti R,Malik SG

更新日期：2019-05-01 00:00:00

abstract：INTRODUCTION:Statins induce heme oxygenase-1 (HO-1) expression in vitro and in vivo. Low HO-1 expression is associated with pregnancy complications, e.g. preeclampsia and recurrent miscarriages. Here, we investigated the effects of pravastatin on HO-1 expression, placental development, and fetal survival in mice with a...

journal_title：Placenta

authors： Tsur A,Kalish F,Burgess J,Nayak NR,Zhao H,Casey KM,Druzin ML,Wong RJ,Stevenson DK

更新日期：2019-01-01 00:00:00

abstract：INTRODUCTION:Gestational diabetes mellitus (GDM) is an increasing harm in pregnancy. Inflammatory processes in the placenta seem to have an influence on pathogenesis besides known factors like maternal BMI. Galectin-13 (gal-13) is an immunoregulatory protein, which is suspected to play a role in development of GDM in t...

journal_title：Placenta

authors： Unverdorben L,Hüttenbrenner R,Knabl J,Jeschke U,Hutter S

更新日期：2015-02-01 00:00:00

abstract：:Cytophotometric measurement of the DNA content of Feulgen-stained nuclei in touch preparations of bovine placentomes (n =5) revealed that 8C nuclei occurred in all, 16C nuclei in two, and 32C nuclei in one specimen. The determination of ploidy level by in situ hybridization with a Y-chromosome specific DNA probe showe...

journal_title：Placenta

authors： Klisch K,Hecht W,Pfarrer C,Schuler G,Hoffmann B,Leiser R

更新日期：1999-07-01 00:00:00

abstract：:Placental ultrasonographic, bio- and histochemical studies were performed on four unrelated fetuses affected with Niemann-Pick disease Type A, following prostaglandin-induced abortion at about the 19th week of gestation. An accumulation of sphingomyelin in the placentae of affected fetuses indicates the essential role...

journal_title：Placenta

authors： Schoenfeld A,Abramovici A,Klibanski C,Ovadia J

更新日期：1985-01-01 00:00:00

abstract：:We investigated the localization of the three subtypes of (Fc gamma R) in the normal human placenta using immunohistochemical and immunocytochemical techniques with specific monoclonal antibodies. The analysis revealed that Fc gamma RI was expressed on Hofbauer cells, that Fc gamma RII was expressed on Hofbauer cells ...

journal_title：Placenta

authors： Kameda T,Koyama M,Matsuzaki N,Taniguchi T,Saji F,Tanizawa O

更新日期：1991-01-01 00:00:00

abstract：INTRODUCTION:Pregnancy complicated by diabetes mellitus (DM) is a central obstetric problem often complicated by fetal macrosomia and increased risk of intrapartum asphyxia. This risk might be explained by fetoplacental vascular abnormalities. This study aimed to investigate the fetoplacental vascular volume by placent...

journal_title：Placenta

authors： Thunbo MØ,Sinding M,Bogaard P,Korsager AS,Frøkjær JB,Østergaard LR,Petersen A,Sørensen A

更新日期：2018-09-01 00:00:00

abstract：:Members of the transmembrane emp24 domain (Tmed)/p24 family of proteins are required for transport of proteins between the endoplasmic reticulum and the Golgi. One member of this family, Tmed2/p24β1, is expressed during placental development in mice and its expression is required for normal development of the labyrint...

journal_title：Placenta

authors： Zakariyah A,Hou W,Slim R,Jerome-Majewska L

更新日期：2012-03-01 00:00:00