The role of chorionic cytotrophoblasts in the smooth chorion fusion with parietal decidua.

Abstract:

BACKGROUND/PURPOSE:Human placenta and chorion are rapidly growing transient embryonic organs built from diverse cell populations that are of either, ectodermal [placenta and chorion specific trophoblast (TB) cells], or mesodermal origin [villous core and chorionic mesenchyme]. The development of placenta and chorion is synchronized from the earliest phase of implantation. Little is known about the formative stages of the human chorion, in particular the steps between the formation of a smooth chorion and its fusion with the parietal decidua. METHODS:We examined the available histological material using immunohistochemistry, and further analyzed in vitro the characteristics of the recently established and reported human self-renewing trophoblast progenitor cells (TBPC) derived from chorionic mesoderm. RESULTS:Here, we provided evidence that the mechanism by which smooth chorion fuses with parietal decidua is the invasion of smooth chorionic cytotrophoblasts (schCTBs) into the uterine wall opposite to the implantation side. This process, which partially replicates some of the mechanisms of the blastocyst implantation, leads to the formation of a new zone of contacts between fetal and maternal cells. CONCLUSION:We propose the schCTBs invasion of the parietal decidua as a mechanism of 'fusion' of the membranes, and that schCTBs in vivo contribute to the pool of the invasive schCTB.

journal_name

Placenta

journal_title

Placenta

authors

Genbačev O,Vićovac L,Larocque N

doi

10.1016/j.placenta.2015.05.002

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

716-22

issue

7

eissn

0143-4004

issn

1532-3102

pii

S0143-4004(15)00920-0

journal_volume

36

pub_type

杂志文章

相关文献

PLACENTA文献大全
  • The multiplication of three different isolates of group B streptococci in pregnant mice.

    abstract::The ability of three streptococcal isolates of different pathogenicity to multiply in the tissues of pregnant mice was investigated following intravenous injection. The highly pathogenic isolate multiplied most rapidly whilst the isolate of low pathogenicity showed the least rapid growth within the observation period ...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/s0143-4004(81)80001-x

    authors: Coid CR,Nicholson J

    更新日期:1981-07-01 00:00:00

  • Polyploidization in the trophoblast and uterine glandular epithelium of the endotheliochorial placenta of silver fox (Vulpes fulvus Desm.), as revealed by the DNA content.

    abstract::Dynamics of genome multiplication during establishment of interrelations between trophoblast and glandular epithelium of the endometrium has been studied in the course of formation of placenta in the silver fox. During formation of the placenta, penetration of the trophoblast into the zone of the endometrial glandular...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1053/plac.2001.0675

    authors: Zybina TG,Zybina EV,Kiknadze II,Zhelezova AI

    更新日期:2001-05-01 00:00:00

  • Histological changes in the umbilical artery following severe chorioamnionitis and funisitis may be indicative of early atherosclerosis.

    abstract::We investigated whether histological evidence of early atherosclerosis was present in the umbilical artery of 21 pregnancies complicated by severe perinatal inflammation, and 21 controls matched for gestational age, sex and birth weight. Severe chorioamnionitis with funisitis was associated with increased numbers of C...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2016.12.021

    authors: Rafferty AR,D'Arcy C,Cann L,Pyman J,Rogers P,Davis PG,Nowell C,Burgner D

    更新日期:2017-02-01 00:00:00

  • Isolation of phenotypically distinct trophoblast cell lines from normal rat chorioallantoic placentas.

    abstract::Growth characteristics and the expression of trophoblast-associated markers by six cell lines generated from midgestation chorioallantoic placentas of outbred (Holtzman) and inbred (Lewis, PVG.RT Ir8) rats were evaluated. The cells comprising all cell lines were epithelioid (contained cytokeratin-type intermediate fil...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/0143-4004(89)90038-6

    authors: Hunt JS,Deb S,Faria TN,Wheaton D,Soares MJ

    更新日期:1989-03-01 00:00:00

  • Placental volume and vascular flow assessed by 3D power Doppler and adverse pregnancy outcomes.

    abstract:OBJECTIVE:To estimate the utility of first-trimester 3D-placental volume and vascular flow indices in the prediction of adverse pregnancy outcomes. METHODS:A prospective cohort study including women with singleton pregnancies seen between 11 and 14 weeks as part of a screening program for aneuploidy. Placental volume ...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2011.01.010

    authors: Odibo AO,Goetzinger KR,Huster KM,Christiansen JK,Odibo L,Tuuli MG

    更新日期:2011-03-01 00:00:00

  • Aspirin inhibits expression of sFLT1 from human cytotrophoblasts induced by hypoxia, via cyclo-oxygenase 1.

    abstract:INTRODUCTION:Elevated circulating soluble FLT1 (sFLT1) levels seen in preeclampsia may play a role in its development. Aspirin is recommended for prevention of preeclampsia. We hypothesized that aspirin may inhibit the production of sFlt1. METHODS:Placentas from women with and without preeclampsia were collected. Prim...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2015.01.004

    authors: Li C,Raikwar NS,Santillan MK,Santillan DA,Thomas CP

    更新日期:2015-04-01 00:00:00

  • Cross-sectional features and three-dimensional structure of human placental villi.

    abstract::Human placental villi from both normal and complicated pregnancies were examined by both light and scanning electron microscopy. The findings provide evidence that histological features such as syncytial sprouts, bridges, and a net-like arrangement of villi represent tangential sections of irregularly shaped villi rat...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/0143-4004(87)90047-6

    authors: Kaufmann P,Luckhardt M,Schweikhart G,Cantle SJ

    更新日期:1987-05-01 00:00:00

  • Placental histological lesions in fetal and neonatal alloimmune thrombocytopenia: A retrospective cohort study of 21 cases.

    abstract:BACKGROUND:Alloimmunization against human platelet antigens (HPAs) can occur prenatally and induce fetal/neonatal alloimmune thrombocytopenia (FNAIT). The aim of this study was to identify placental histological features associated with platelet alloimmunization and their clinical significance. METHODS:This study exam...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2016.10.009

    authors: Dubruc E,Lebreton F,Giannoli C,Rabilloud M,Huissoud C,Devouassoux-Shisheboran M,Allias F

    更新日期:2016-12-01 00:00:00

  • Fat-soluble nutrients and Omega-3 fatty acids as modifiable factors influencing preterm birth risk.

    abstract::Preterm birth is a leading cause of child morbidity and mortality, so strategies to reduce early birth must remain a priority. One key approach to enhancing birth outcomes is improving maternal dietary intake. Therefore, the purpose of this review is to discuss mechanisms on perinatal status of fat-soluble nutrients (...

    journal_title:Placenta

    pub_type: 杂志文章,评审

    doi:10.1016/j.placenta.2019.12.002

    authors: Thoene M,Van Ormer M,Yuil-Valdes A,Bruett T,Natarajan SK,Mukherjee M,Thompson M,Nordgren TM,Van Lippevelde W,Overby NC,Adu-Bonsaffoh K,Anderson-Berry A,Hanson C

    更新日期:2020-09-01 00:00:00

  • Identification of triploidy by DA/DAPI staining of trophoblastic interphase nuclei.

    abstract::Combined staining of non-cultured interphase nuclei from hydatidiform moles with distamycin A and DAPI resulted in the presence of specific stained interphase bodies. A mean number of six interphase bodies was observed in moles with a diploid karyotype and a mean number of nine interphase bodies was observed in triplo...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/s0143-4004(85)80046-1

    authors: Tommerup N,Vejerslev LO

    更新日期:1985-07-01 00:00:00

  • Placental release of distinct DNA-associated micro-particles into maternal circulation: reflective of gestation time and preeclampsia.

    abstract:BACKGROUND:The aim of this study was to determine whether DNA-associated micro-particles (MPs) in maternal plasma express fetal-derived human leukocyte antigen-G (HLA-G) or placental alkaline phosphatase (PLAP) and whether the levels differ between women with normotensive pregnancies and preeclampsia. METHODS:DNA-asso...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2009.06.012

    authors: Orozco AF,Jorgez CJ,Ramos-Perez WD,Popek EJ,Yu X,Kozinetz CA,Bischoff FZ,Lewis DE

    更新日期:2009-10-01 00:00:00

  • Microchimerism: Defining and redefining the prepregnancy context - A review.

    abstract::Bidirectional transplacental exchange characterizes human pregnancy. Cells exchanged between mother and fetus can durably persist as microchimerism and may have both short- and long-term consequences for the recipient. The amount, type, and persistence of microchimerism are influenced by obstetric characteristics, pre...

    journal_title:Placenta

    pub_type: 杂志文章,评审

    doi:10.1016/j.placenta.2017.08.071

    authors: Gammill HS,Harrington WE

    更新日期:2017-12-01 00:00:00

  • Paracellular permeability pathways in the human placenta: a quantitative and morphological study of maternal-fetal transfer of horseradish peroxidase.

    abstract::Physiological data indicate that both a transcellular and a paracellular pathway are available for transfer across the human placenta but the morphological correlate of the latter is uncertain. We measured the permeability of the dually perfused human placental cotyledon to the predominantly cationic protein horseradi...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/s0143-4004(05)80249-8

    authors: Edwards D,Jones CJ,Sibley CP,Nelson DM

    更新日期:1993-01-01 00:00:00

  • The chemokine connection: hormonal and embryonic regulation at the human maternal-embryonic interface--a review.

    abstract::Chemokines are small polypeptides that attract specific leukocyte subsets by binding to cell-surface receptors. In reproductive biology, they have been implicated in ovulation, menstruation, and embryo implantation, and pathological processes such as preterm delivery, HIV infection, and endometriosis. It is known that...

    journal_title:Placenta

    pub_type: 杂志文章,评审

    doi:10.1016/s0143-4004(03)00134-6

    authors: Dominguez F,Pellicer A,Simon C

    更新日期:2003-10-01 00:00:00

  • Oestrogen and progesterone receptors in human term placenta. Measurement by binding assays and immunological methods.

    abstract::Oestrogen and progesterone receptors have been implicated in human placental steroidogenesis, but studies developed to measure their concentration in this tissue at term yielded discrepant results. Potential inaccuracy of the binding assays, the technique used in previous studies, might influence the discrepancy. In t...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/0143-4004(89)90049-0

    authors: Rivera J,Cano A

    更新日期:1989-11-01 00:00:00

  • A distal-less class homeobox gene, DLX4, is a candidate for regulating epithelial-mesenchymal cell interactions in the human placenta.

    abstract::Homeobox genes of the Distal-less (Dlx) family are expressed in the vertebrate embryo in regions where epithelial cell layers contact adjacent mesenchymal cells. This study shows that the human Dlx family member, DLX4, is expressed in the placenta, primarily in regions where epithelial and mesenchymal cell layers cont...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/s0143-4004(98)90103-5

    authors: Quinn LM,Latham SE,Kalionis B

    更新日期:1998-01-01 00:00:00

  • Calcitonin gene-related peptide receptor in human placental syncytiotrophoblast brush-border and basal plasma membranes.

    abstract::Minerals, such as calcium and potassium, are essential for fetal development, but their transplacental transport, and in particular, the effect of hormones on this process has not been extensively studied. Human alpha-calcitonin gene-related peptide (h alpha CGRP), a hormone constituted of 37 amino acids, is obtained ...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/s0143-4004(97)90091-6

    authors: Lafond J,St-Pierre S,Masse A,Savard R,Simoneau L

    更新日期:1997-03-01 00:00:00

  • Estimation of the burden of human placental micro- and nano-vesicles extruded into the maternal blood from 8 to 12 weeks of gestation.

    abstract:BACKGROUND:The human placenta extrudes a variety of extracellular vesicles (EVs) into the maternal blood daily. These vesicles may be crucial to the adaptation of the maternal cardiovascular and immune systems to pregnancy. Quantifying the EVs that are released in early gestation is important to our understanding of ho...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2018.10.009

    authors: Liu H,Kang M,Wang J,Blenkiron C,Lee A,Wise M,Chamley L,Chen Q

    更新日期:2018-12-01 00:00:00

  • Escherichia coli-induced temporal and differential secretion of heat-shock protein 70 and interleukin-1β by human fetal membranes in a two-compartment culture system.

    abstract:INTRODUCTION:Escherichia coli is recognized as an etiological bacteria associated with chorioamnionitis and the preterm premature rupture of fetal membranes. This pathological condition induces pro-inflammatory cytokines and degradative metalloproteinases, which are considered biological markers secreted in an acute st...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2014.12.011

    authors: Osorio-Caballero M,Perdigón-Palacio C,García-López G,Flores-Herrera O,Olvera-Sánchez S,Morales-Méndez I,Sosa-González I,Acevedo JF,Guzmán-Grenfell AM,Molina-Hernández A,Díaz NF,Flores-Herrera H

    更新日期:2015-03-01 00:00:00

  • Specific infiltration pattern of FOXP3+ regulatory T cells in chronic histiocytic intervillositis of unknown etiology.

    abstract:INTRODUCTION:Chronic histiocytic intervillositis of unknown etiology (CIUE) is a rare placental lesion characterized by an intervillous mononuclear inflammatory infiltrate of maternal origin. Although the mechanism and origin of these lesions are currently not understood, they appear to be related to an immune conflict...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2012.12.004

    authors: Capuani C,Meggetto F,Duga I,Danjoux M,March M,Parant O,Brousset P,Aziza J

    更新日期:2013-02-01 00:00:00

  • Altered maternal and placental lipid metabolism and fetal fat development in obesity: Current knowledge and advances in non-invasive assessment.

    abstract::Abnormal maternal lipid profiles, a hallmark of increased maternal adiposity, are associated with pregnancy complications such as preeclampsia and gestational diabetes, and offspring long-term metabolic health is impacted as the consequence of altered fetal growth, physiology and often iatrogenic prematurity. The meta...

    journal_title:Placenta

    pub_type: 杂志文章,评审

    doi:10.1016/j.placenta.2018.05.011

    authors: Delhaes F,Giza SA,Koreman T,Eastabrook G,McKenzie CA,Bedell S,Regnault TRH,de Vrijer B

    更新日期:2018-09-01 00:00:00

  • MicroRNA expression profiles of trophoblastic cells.

    abstract:BACKGROUND:MicroRNAs (miRNAs) are small single-stranded RNA molecules working as post-transcriptional modulators of gene expression. Trophoblast cells are a heterogenous group of fetal cells forming the feto-maternal interface and displaying a wide spectrum of functions. The regulation of their behavior may partly unde...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2012.05.009

    authors: Morales-Prieto DM,Chaiwangyen W,Ospina-Prieto S,Schneider U,Herrmann J,Gruhn B,Markert UR

    更新日期:2012-09-01 00:00:00

  • The atrial natriuretic peptide (ANP) knockout mouse does not exhibit the phenotypic features of pre-eclampsia or demonstrate fetal growth restriction.

    abstract::The ANP knockout mouse is reported to exhibit pregnancy-associated hypertension, proteinuria and impaired placental trophoblast invasion and spiral artery remodeling, key features of pre-eclampsia (PE). We hypothesized that these mice may provide a relevant model of human PE with associated fetal growth restriction (F...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2016.04.003

    authors: Finn-Sell SL,Renshall LJ,Cowley EJ,Dilworth MR,Wareing M,Greenwood SL,Sibley CP,Cottrell EC

    更新日期:2016-06-01 00:00:00

  • Aberrations of early trophoblast differentiation predispose to pregnancy failure: lessons from the anti-phospholipid syndrome.

    abstract:OBJECTIVES:The epithelium of the human placenta comprises an inner cytotrophoblast (CT) which proliferates and fuses with the outer differentiated syncytiotrophoblast (ST). Turnover has been studied focussing on second and third trimester placentas but with a paucity of data describing the normal first trimester tropho...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2005.09.007

    authors: Bose P,Kadyrov M,Goldin R,Hahn S,Backos M,Regan L,Huppertz B

    更新日期:2006-08-01 00:00:00

  • The function of miR-519d in cell migration, invasion, and proliferation suggests a role in early placentation.

    abstract::The processes of proliferation, migration, and invasion of extravillous trophoblasts are critical for placental implantation and early development, and directly influence pregnancy outcome. Dysregulation of these processes has been associated with placental dysfunction, implicated in clinical conditions such as preecl...

    journal_title:Placenta

    pub_type: 杂志文章,评审

    doi:10.1016/j.placenta.2016.10.004

    authors: Xie L,Sadovsky Y

    更新日期:2016-12-01 00:00:00

  • Human placentation from nidation to 5 weeks of gestation. Part I: What do we know about formative placental development following implantation?

    abstract::The implantation of the blastocyst and early development of the placenta are crucial for the success of implantation and pregnancy. However, the formative stages of human placental development are largely unknown because of their existence in a 'black box' where access to samples is extremely limited for ethical reaso...

    journal_title:Placenta

    pub_type: 杂志文章,评审

    doi:10.1016/j.placenta.2012.01.020

    authors: James JL,Carter AM,Chamley LW

    更新日期:2012-05-01 00:00:00

  • Cryopreservation of placental biopsies for mitochondrial respiratory analysis.

    abstract::Mitochondrial function is required to support energetically-demanding processes in the placenta. As such, a compromise in mitochondrial function could severely impact fetal growth and development. Respirometry is a highly useful method for studying mitochondrial function, but is not possible in freeze-thawed mitochond...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2011.11.019

    authors: Colleoni F,Morash AJ,Ashmore T,Monk M,Burton GJ,Murray AJ

    更新日期:2012-02-01 00:00:00

  • Gene expression of nitric oxide synthase in cultured human term placental trophoblast during in vitro differentiation.

    abstract::The human placental syncytiotrophoblast is derived from differentiating cytotrophoblasts and is in contact with maternal blood. This endothelial function positions the trophoblast to regulate maternal-fetal exchange and to influence circulatory dynamics through paracrine interactions in the placenta. Two isoforms of n...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/s0143-4004(98)90056-x

    authors: Lyall F,Jablonka-Shariff A,Johnson RD,Olson LM,Nelson DM

    更新日期:1998-05-01 00:00:00

  • Review: The feto-placental unit, pregnancy pathology and impact on long term maternal health.

    abstract::Pregnancy induces a number of alterations to maternal physiology to accommodate the increased demands made by the developing fetus and placenta. These alterations appear at least in part to be driven by products derived from the feto-placental unit, including microchimeric cells, as well as placental exosomes and micr...

    journal_title:Placenta

    pub_type: 杂志文章,评审

    doi:10.1016/j.placenta.2011.11.005

    authors: Clifton VL,Stark MJ,Osei-Kumah A,Hodyl NA

    更新日期:2012-02-01 00:00:00

  • Study on the expression of angiotensin II (ANG II) receptor subtype 1 (AT1R) in the placenta of pregnancy-induced hypertension.

    abstract:OBJECTIVE:To study the expression of angiotensin II (ANG II) receptor subtype 1 (AT(1)R) in the human placenta with pregnancy-induced hypertension (PIH). METHODS:Immunohistochemistry was used to detect the expression of AT(1)R in placental tissues of 30 patients with PIH and 10 patients with normal pregnancies (contro...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2004.01.026

    authors: Thapa L,He CM,Chen HP

    更新日期:2004-08-01 00:00:00