Placental ultrasonographic biochemical and histochemical studies in human fetuses affected with Niemann-Pick disease type A.

abstract：:Respiratory parameters were studied in mitochondria from human placenta. Respiratory control and ADP/O ratios were low in this preparation. The adenine nucleotide content of placental mitochondria was found to be only one quarter of that found for adult uterine muscle tissue mitochondria prepared in the same way. Load...

journal_title：Placenta

authors： Illsley NP,Coade SB,Harkness RA

更新日期：1985-05-01 00:00:00

abstract：INTRODUCTION:A major issue in the transcriptomic study of spontaneous preterm birth (sPTB) in humans is the inability to collect healthy control tissue at the same gestational age (GA) to compare with pathologic preterm tissue. Thus, gene expression differences identified after the standard comparison of sPTB and term ...

journal_title：Placenta

authors： Eidem HR,Rinker DC,Ackerman WE 4th,Buhimschi IA,Buhimschi CS,Dunn-Fletcher C,Kallapur SG,Pavličev M,Muglia LJ,Abbot P,Rokas A

更新日期：2016-05-01 00:00:00

abstract：:Physiological data indicate that both a transcellular and a paracellular pathway are available for transfer across the human placenta but the morphological correlate of the latter is uncertain. We measured the permeability of the dually perfused human placental cotyledon to the predominantly cationic protein horseradi...

journal_title：Placenta

authors： Edwards D,Jones CJ,Sibley CP,Nelson DM

更新日期：1993-01-01 00:00:00

abstract：INTRODUCTION:We have identified some critical aspects concerning umbilical cord tissue mesenchymal stem cells: the lack of standards for cell isolation, expansion and cryopreservation, the lack of unanimous opinions upon their multilineage differentiation potential and the existence of very few results related to the f...

journal_title：Placenta

authors： Dulugiac M,Moldovan L,Zarnescu O

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:In humans, it is known that blood flow is directed to the gravid uterus from two (right and left) pelvic uterine arteries. The extent of supply from the tubo-ovarian anastomosis (joining of the ovarian and uterine arteries) is unknown. The aim of this study was to delineate the arterial blood supply to the p...

journal_title：Placenta

authors： Balasuriya H,Bell P,Waugh R,Thompson J,Gillin A,Hennessy A,Makris A

更新日期：2010-01-01 00:00:00

abstract：:The present study was designed to quantify the major cellular metabolites in human placentae and their changes due to the confounding effect of time and subsequent hypoxia during sample collection using magnetic resonance spectroscopy ((1)H-and (31)P-MRS). The absolute placental concentrations of lactate, glucose, maj...

journal_title：Placenta

authors： Serkova N,Bendrick-Peart J,Alexander B,Tissot van Patot MC

更新日期：2003-02-01 00:00:00

abstract：:Human placental tissues have been shown to contain gonadotrophin-releasing hormone-(GnRH)-like activity. Thus, the effect of a potent GnRH antagonist (N-Ac-Pro1,D-p-Cl-Phe2,D-Nal(2)3,6-GnRH, obtained from Syntex Laboratories) on placental hormonal release was studied. Explant cultures of placentae of 6 to 15 weeks' ge...

journal_title：Placenta

authors： Siler-Khodr TM,Khodr GS,Rhode J,Vickery BH,Nestor JJ Jr

更新日期：1987-01-01 00:00:00

abstract：:Mitochondrial function is required to support energetically-demanding processes in the placenta. As such, a compromise in mitochondrial function could severely impact fetal growth and development. Respirometry is a highly useful method for studying mitochondrial function, but is not possible in freeze-thawed mitochond...

journal_title：Placenta

authors： Colleoni F,Morash AJ,Ashmore T,Monk M,Burton GJ,Murray AJ

更新日期：2012-02-01 00:00:00

abstract：:Uptake and metabolism of adenosine by human placenta were studied using the single-circulation paired-tracer technique. When isolated cotyledons were perfused through the fetal (basal) circulation at mean pressures of 36 +/- 3.3 mmHg and mean flow rates of 6.6 +/- 0.3 ml/min the maximal [3H]adenosine uptake was 51.3 +...

journal_title：Placenta

authors： Acevedo CG,Rojas S,Ramirez M,Bravo I

更新日期：1995-10-01 00:00:00

abstract：:Superficial invasion of extravillous trophoblasts (EVTs) and impaired spiral artery remodelling are characterizing phenomena in pregnancies complicated by pre-eclampsia (PE) and fetal growth restriction (FGR). However, the underlying causes remain unclear. In this study, gene expression in decidua basalis tissue from ...

journal_title：Placenta

authors： Lian IA,Toft JH,Olsen GD,Langaas M,Bjørge L,Eide IP,Børdahl PE,Austgulen R

更新日期：2010-07-01 00:00:00

abstract：INTRODUCTION:Preterm birth is a heterogeneous phenotype, with placental abnormalities underlying many cases. The etiology of preterm births that occur in the absence of placental abnormalities, however, remain enigmatic and we considered that early pregnancy biomarkers may provide clues. METHODS:Women from a hospital-...

journal_title：Placenta

authors： Sun B,Parks WT,Simhan HN,Bertolet M,Catov JM

更新日期：2020-01-01 00:00:00

abstract：:Annexins are soluble proteins that bind to biological membranes containing negatively charged phospholipids, principally phosphatidylserine, in a Ca(2+)-dependent manner. Annexin-A5 (AnxA5), the smallest member of the annexin family, presents unique properties of membrane binding and self-assembly into ordered two-dim...

journal_title：Placenta

authors： Bouter A,Carmeille R,Gounou C,Bouvet F,Degrelle SA,Evain-Brion D,Brisson AR

更新日期：2015-04-01 00:00:00

abstract：:The permeability of the rat placenta at 21 days' gestation (term is 23 days) has been measured with fetuses intact in situ and by perfusion of the fetal circulation. Intact measurements were made by removal of fetuses at known time intervals after injection of radioisotopes to the anaesthetized mother and measurement ...

journal_title：Placenta

authors： Robinson NR,Atkinson DE,Jones CJ,Sibley CP

更新日期：1988-07-01 00:00:00

abstract：:This study examines middle and late gestational placentae from 13 Tayassu tajacu (collared peccary) and 3 Tayassu pecari (white-lipped peccary), which are Artiodactyla belonging to the Family Tayassuidae. The chorionic sac of Tayassu species is diffuse and chorioallantoic. These epitheliochorial placentae show no trop...

journal_title：Placenta

authors： Santos TC,Dantzer V,Jones CJ,Oliveira MF,Miglino MA

更新日期：2006-02-01 00:00:00

abstract：:Homeobox genes of the Distal-less (Dlx) family are expressed in the vertebrate embryo in regions where epithelial cell layers contact adjacent mesenchymal cells. This study shows that the human Dlx family member, DLX4, is expressed in the placenta, primarily in regions where epithelial and mesenchymal cell layers cont...

journal_title：Placenta

authors： Quinn LM,Latham SE,Kalionis B

更新日期：1998-01-01 00:00:00

abstract：:Human papillomavirus (HPV) are more prevalent in spontaneous abortions than elect abortions and preferentially infect the trophoblasts. Related to this, HPV type 16 has been shown to productively replicate in 3A trophoblasts in tissue culture. Extending these earlier studies, the described study addresses the issue wh...

journal_title：Placenta

authors： You H,Liu Y,Agrawal N,Prasad CK,Edwards JL,Osborne AF,Korourian S,Lowery CL,Hermonat PL

更新日期：2008-01-01 00:00:00

abstract：:The marginal zone of the human term placenta was studied by transmission electron microscopy and immunohistochemistry using antibodies against cytoskeletal filaments, extracellular matrix molecules and endothelial markers. The marginal sinus of the intervillous space is separated from the chorionic and basal plates by...

journal_title：Placenta

authors： Nanaev AK,Kosanke G,Kemp B,Frank HG,Huppertz B,Kaufmann P

更新日期：2000-01-01 00:00:00

abstract：:Fetal growth restriction (FGR) is the failure of a fetus to reach its full genetic growth potential. It occurs in up to 8% of pregnancies, and after premature birth is the second leading cause of infant mortality and morbidity. There is no treatment currently available for FGR. Its primary cause, when not attributable...

journal_title：Placenta

authors： Swanson AM,David AL

更新日期：2015-06-01 00:00:00

abstract：:Combined staining of non-cultured interphase nuclei from hydatidiform moles with distamycin A and DAPI resulted in the presence of specific stained interphase bodies. A mean number of six interphase bodies was observed in moles with a diploid karyotype and a mean number of nine interphase bodies was observed in triplo...

journal_title：Placenta

authors： Tommerup N,Vejerslev LO

更新日期：1985-07-01 00:00:00

abstract：:Direct measurements of electrical potential and input resistance were performed on the syncytial membrane facing maternal blood. The potentials varied according to the external potassium ion levels and, to a lesser extent, with sodium ion concentrations. Ouabain provoked a rapid and consistent depolarization which ind...

journal_title：Placenta

authors： Bara M,Challier JC,Guiet-Bara A

更新日期：1988-03-01 00:00:00

abstract：:Maturation of the fetal hypothalamic-pituitary-axis may be an important factor in the stimulation of the onset of parturition. Recent studies have found that corticotrophin-releasing hormone (CRH), the hypothalamic component of this axis is also present in the placenta and the fetal membranes. We review the evidence d...

journal_title：Placenta

authors： Riley SC,Challis JR

更新日期：1991-03-01 00:00:00

abstract：:Eighty-one placentae from women with leprosy and 17 placentae from healthy controls were subjected to a detailed macroscopic, light microscopic, ultrastructural, immunopathological, microbiological and biochemical study. The placental morphology and immunohistology were normal, and there was no morphological evidence ...

journal_title：Placenta

authors： Duncan ME,Fox H,Harkness RA,Rees RJ

更新日期：1984-05-01 00:00:00

abstract：:The central role of the placenta in the pathogenesis of pre-eclampsia is undisputed. The evidence that maternal syndrome of pre-eclampsia is caused by a maternal systemic inflammatory response (MSIR) is reviewed. The polymorphic nature of the inflammatory network explains the diversity of the varied signs of this cond...

journal_title：Placenta

authors： Redman CW,Sargent IL

更新日期：2003-04-01 00:00:00

abstract：:Corticosteroid conversion by early (7 to 10 weeks) and late (36 to 42 weeks) human placenta, fetal membranes and decidua was studied. Tritiated cortisol, cortisone, corticosterone, 11-dehydrocorticosterone (DHC) and 11-deoxycorticosterone (DOC) were incubated in vitro with homogenates of these tissues and extracts chr...

journal_title：Placenta

authors： López Bernal A,Craft IL

更新日期：1981-10-01 00:00:00

abstract：INTRODUCTION:Preeclampsia (PE) is one of the leading causes of maternal mortality and morbidity worldwide. Recently, the role of epigenetic modifications in preeclampsia has been a focus of research. This study was to identified genes or pathways that may be associated with PE, and discuss whether the changes in the me...

journal_title：Placenta

authors： Li Y,Cui S,Shi W,Yang B,Yuan Y,Yan S,Li Y,Xu Y,Zhang Z,Linlin Zhang

更新日期：2020-04-01 00:00:00

abstract：:Stereological methods were used to test whether or not altitudinal, ethnic and sex differences in birthweight in Bolivia are associated with differences in placental morphology. Estimates of the volumes, surface areas, lengths and diameters of villi and of fetal capillaries were obtained by analysing paraffin sections...

journal_title：Placenta

authors： Jackson MR,Mayhew TM,Haas JD

更新日期：1987-09-01 00:00:00

abstract：UNLABELLED:Betamethasone (BET) is a widely used treatment for women who are at high risk of preterm delivery. In sheep, BET-induced growth restriction was found to be associated with reduced placenta lactogen (PL), a key regulator of fetal growth. We therefore hypothesized that also in humans a single course of BET adm...

journal_title：Placenta

authors： Braun T,Husar A,Challis JR,Dudenhausen JW,Henrich W,Plagemann A,Sloboda DM

更新日期：2013-05-01 00:00:00

abstract：:During pregnancy, changes in oxygen tension are essential for proper embryonic and placental development. Little is known about the mechanisms underlying mammalian cellular adaptations to changes in oxygen tension. Currently, we have explored putative mechanisms by which human trophoblast cells may sense oxygen. In or...

journal_title：Placenta

authors： De Marco CS,Caniggia I

更新日期：2002-04-01 00:00:00

abstract：INTRODUCTION:Alcohol consumption is a common social practice among women of childbearing age. With 50% of pregnancies being unplanned, many embryos are exposed to alcohol prior to pregnancy recognition and formation of the placenta. The effects of periconceptional (PC) alcohol exposure on the placenta are unknown. MET...

journal_title：Placenta

authors： Gårdebjer EM,Cuffe JS,Pantaleon M,Wlodek ME,Moritz KM

更新日期：2014-01-01 00:00:00

abstract：:Human amniotic epithelium from patients with normal pregnancy (normal amniotic epithelium) and from patients with materno-fetal rhesus incompatibility has been examined under the light and electron microscope. In comparison with normal amniotic epithelium, the epithelium in rhesus incompatibility displays the followin...

journal_title：Placenta

authors： Wang T

更新日期：1981-01-01 00:00:00