Review: Annexin-A5 and cell membrane repair.

abstract：:The aim of this work was to characterize the uptake of 1-methyl-4-phenylpyridinium (MPP(+)) in the JAR human choriocarcinoma cell line. As JAR cells, as well as the placenta, express the neuronal serotonin transporter (SERT), a comparison between the uptake of (3)H-MPP(+) and (3)H-serotonin ((3)H-5HT) was made. Specif...

journal_title：Placenta

authors： Martel F,Keating E

更新日期：2003-04-01 00:00:00

abstract：INTRODUCTION:Human decidual stromal cells (DSCs) play a key role in maternal-fetal interactions. Precursors of DSCs (preDSCs) localize around vessels in both the endometrium and decidua. Previous studies suggested a relationship between preDSCs and pericytes because these cells share a perivascular location, alpha smoo...

journal_title：Placenta

authors： Muñoz-Fernández R,de la Mata C,Prados A,Perea A,Ruiz-Magaña MJ,Llorca T,Fernández-Rubio P,Blanco O,Abadía-Molina AC,Olivares EG

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To study the association between velamentous cord insertion (VCI) and different outcomes in monochorionic twins with and without twin-twin transfusion syndrome (TTTS). METHODS:We recorded the cord insertion type in all consecutive monochorionic placentas examined in two tertiary medical centers. The associat...

journal_title：Placenta

authors： Costa-Castro T,De Villiers S,Montenegro N,Severo M,Oepkes D,Matias A,Lopriore E

更新日期：2013-11-01 00:00:00

abstract：:Sections of human term placentae delivered at low and high altitude to indigenous and non-indigenous populations in Bolivia were analysed by stereological methods. Estimates were obtained of the arithmetic and harmonic mean thicknesses of villous membrane and of trophoblast. These values were then used to derive indic...

journal_title：Placenta

authors： Jackson MR,Mayhew TM,Haas JD

更新日期：1988-01-01 00:00:00

abstract：:The walls of uterine spiral arteries are invaded by extravillous trophoblast cells and are thereby converted to the uteroplacental arteries of pregnancy. The mechanisms by which this invasion occurs are not understood, but the extracellular matrices that are breached suggest participation by specific proteinases. In t...

journal_title：Placenta

authors： Blankenship TN,King BF

更新日期：1994-02-01 00:00:00

abstract：:Several xenobiotic-metabolizing mono-oxygenase activities, in conjunction with the immunohistochemical localization of the respective cytochrome P-450 forms, were investigated in placentae from smoking and non-smoking women. The antibodies used in the immunohistochemical analyses were monoclonal antibodies (MAbs) 1-7-...

journal_title：Placenta

authors： Pasanen M,Stenbäck F,Park SS,Gelboin HV,Pelkonen O

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVES:Microbial-specific factors are likely critical in determining whether bacteria trigger preterm labor. Structural variations in lipopolysaccharide (LPS), a component of gram-negative bacteria, can determine whether LPS has an inflammatory (agonist) or anti-inflammatory (antagonist) effect through Toll-like re...

journal_title：Placenta

authors： Chang J,Jain S,Carl DJ,Paolella L,Darveau RP,Gravett MG,Adams Waldorf KM

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Alloimmunization against human platelet antigens (HPAs) can occur prenatally and induce fetal/neonatal alloimmune thrombocytopenia (FNAIT). The aim of this study was to identify placental histological features associated with platelet alloimmunization and their clinical significance. METHODS:This study exam...

journal_title：Placenta

authors： Dubruc E,Lebreton F,Giannoli C,Rabilloud M,Huissoud C,Devouassoux-Shisheboran M,Allias F

更新日期：2016-12-01 00:00:00

abstract：:The morphometric oxygen diffusive conductance (D(p)) of the placenta provides a measure of the efficiency of oxygen transfer between the mother and the developing fetus. Any change in the D(p)may point towards possible adaptation in the light of altered oxygen transfer. Placentae from normal (n=40) and small for gesta...

journal_title：Placenta

authors： Ansari T,Fenlon S,Pasha S,O'Neill B,Gillan JE,Green CJ,Sibbons PD

更新日期：2003-07-01 00:00:00

abstract：:Preeclampsia (PE) affects 5-8% of pregnancies and is responsible for 18% of maternal deaths in the US, and for long-term complications in mother and child. PE is an inflammatory state and may influence placental function in a sex-specific manner. We determined if there is a sexual dimorphism in the placental inflammat...

journal_title：Placenta

authors： Muralimanoharan S,Maloyan A,Myatt L

更新日期：2013-12-01 00:00:00

abstract：INTRODUCTION:Preeclampsia (PE) carries increased risks of cardiovascular- and metabolic diseases in mothers and offspring during the life course. While the severe early-onset PE (EOPE) phenotype originates from impaired placentation in early pregnancy, late-onset PE (LOPE) is in particular associated with pre-existing ...

journal_title：Placenta

authors： Herzog EM,Eggink AJ,Willemsen SP,Slieker RC,Wijnands KPJ,Felix JF,Chen J,Stubbs A,van der Spek PJ,van Meurs JB,Steegers-Theunissen RPM

更新日期：2017-10-01 00:00:00

abstract：:The uptake of [3H]choline and its conversion to [3H]acetylcholine were investigated in term human placental tissue in vitro. Although the net uptake of [3H]choline increased throughout a 45 min incubation period, intracellular [3H]choline levels reach a plateau after 2 min. There was a constant increase in [3H]acetylc...

journal_title：Placenta

authors： Leventer SM,Rowell PP

更新日期：1984-05-01 00:00:00

abstract：:Abnormal maternal lipid profiles, a hallmark of increased maternal adiposity, are associated with pregnancy complications such as preeclampsia and gestational diabetes, and offspring long-term metabolic health is impacted as the consequence of altered fetal growth, physiology and often iatrogenic prematurity. The meta...

journal_title：Placenta

authors： Delhaes F,Giza SA,Koreman T,Eastabrook G,McKenzie CA,Bedell S,Regnault TRH,de Vrijer B

更新日期：2018-09-01 00:00:00

abstract：:Maternal and fetal cellular relationships in the normal human term placental basal plate were investigated by single and double immunohistochemical labelling techniques. Extravillous fetal trophoblast in the basal plate was uniformly reactive with markers of low-molecular-weight cytokeratins. The predominant maternal ...

journal_title：Placenta

authors： Bulmer JN,Smith J,Morrison L,Wells M

更新日期：1988-05-01 00:00:00

abstract：OBJECTIVE:To estimate the utility of first-trimester 3D-placental volume and vascular flow indices in the prediction of adverse pregnancy outcomes. METHODS:A prospective cohort study including women with singleton pregnancies seen between 11 and 14 weeks as part of a screening program for aneuploidy. Placental volume ...

journal_title：Placenta

authors： Odibo AO,Goetzinger KR,Huster KM,Christiansen JK,Odibo L,Tuuli MG

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:The antiphospholipid syndrome (APS) is characterized by the presence of circulating antiphospholipid antibodies (aPLs), is a leading cause for thromboembolic events, repeated miscarriage, fetal loss and is a major risk factor for fetal growth restriction (FGR) and preeclampsia. In human, anti-β2 glycoprotein...

journal_title：Placenta

authors： Kawaguchi R,Nunomura S,Umehara N,Nikaido T,Huppertz B,Tanaka T,Ra C

更新日期：2012-07-01 00:00:00

abstract：:Vascularization within the human placenta is the result of the de novo formation of vessels derived from pluripotent precursor cells in the mesenchymal core of the villi. Vascularization of placental villi starts at around day 21 post conception (p.c.) with a four somite embryo. At this stage progenitors of haemangiog...

journal_title：Placenta

authors： Demir R,Kayisli UA,Seval Y,Celik-Ozenci C,Korgun ET,Demir-Weusten AY,Huppertz B

更新日期：2004-07-01 00:00:00

abstract：INTRODUCTION:Placental transport is the main factor affecting the health and development of the fetus. Due to the placenta's geometrical and mathematical complexity, the structure-function relations of placental terminal villi have not been successfully modeled. Hence, a novel modeling approach is proposed. METHODS:Co...

journal_title：Placenta

authors： Plitman Mayo R,Charnock-Jones DS,Burton GJ,Oyen ML

更新日期：2016-07-01 00:00:00

abstract：:MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression at the post-transcriptional level. While mostly intracellular, a portion of cellular miRNAs is released to the circulation and their level in the plasma is altered in certain pathological conditions such as cancer, and also during pregnancy. We...

journal_title：Placenta

authors： Mouillet JF,Chu T,Hubel CA,Nelson DM,Parks WT,Sadovsky Y

更新日期：2010-09-01 00:00:00

abstract：INTRODUCTION:Little is known about the interaction between human placental multipotent mesenchymal stromal cell (hPMSC) and trophoblast. We hypothesize that hPMSCs produce hepatocyte growth factor (HGF) which may interact with trophoblasts and regulate their migration during placentation. METHODS:hPMSCs were isolated ...

journal_title：Placenta

authors： Chen CP,Huang JP,Chu TY,Aplin JD,Chen CY,Wu YH

更新日期：2013-10-01 00:00:00

abstract：:Throughout its entire lifespan, the placenta is able to produce as well as respond to a variety of inflammatory stimuli. Many signaling molecules and concurrent pathways responsible for the propagation of an inflammatory response have been identified in placental cells. From early developmental stages onward, the secr...

journal_title：Placenta

authors： Hauguel-de Mouzon S,Guerre-Millo M

更新日期：2006-08-01 00:00:00

abstract：:Apart from during the prepartal period, the main oestrogen produced by the bovine trophoblast is oestrone sulphate (E1S) which does not bind to nuclear oestrogen receptors (ER). High steroid sulphatase (StS) activities previously detected in the maternal part of bovine placentomes (caruncles) suggest the local activat...

journal_title：Placenta

authors： Greven H,Kowalewski MP,Hoffmann B,Geyer J,Rex-Haffner M,Ugele B,Schuler G

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVES:The epithelium of the human placenta comprises an inner cytotrophoblast (CT) which proliferates and fuses with the outer differentiated syncytiotrophoblast (ST). Turnover has been studied focussing on second and third trimester placentas but with a paucity of data describing the normal first trimester tropho...

journal_title：Placenta

authors： Bose P,Kadyrov M,Goldin R,Hahn S,Backos M,Regan L,Huppertz B

更新日期：2006-08-01 00:00:00

abstract：:As pregnancy progresses the placental syncytiotrophoblast increasingly assumes control of maternal glucose homeostasis through the release and counter-balancing effects of placental lactogen (PL) and placental variant growth hormone (GH-V). While local actions of these hormones on placental growth and function are lik...

journal_title：Placenta

authors： Hill DJ

更新日期：2018-09-01 00:00:00

abstract：:Interleukin-6 (IL-6) and its receptor complex, IL-6 receptor (IL-6R) and gp130, are critical in induction of suppressor of cytokine signalling-3 (SOCS-3) protein, a negative cytokine regulator and anti-inflammatory mediator, in a biological system. Increased inflammatory response is believed to contribute to the place...

journal_title：Placenta

authors： Zhao S,Gu Y,Dong Q,Fan R,Wang Y

更新日期：2008-12-01 00:00:00

abstract：:The aim of this study was to investigate localization and content of activin beta A-subunit and activin receptors in gestational tissues throughout pregnancy and in association with term labour. Placenta and fetal membranes were collected from women undergoing first and second trimester terminations and from women bef...

journal_title：Placenta

authors： Schneider-Kolsky ME,Manuelpillai U,Waldron K,Dole A,Wallace EM

更新日期：2002-04-01 00:00:00

abstract：:Angiotensinogen is the substrate for the enzyme renin. In addition to the well-characterized low molecular weight forms of angiotensinogen, a high molecular weight form (HMrA) comprises about 15 per cent of the total angiotensinogen in plasma of pregnant women. In the current study the different forms of angiotensinog...

journal_title：Placenta

authors： Lenz T,Sealey JE,Tewksbury DA

更新日期：1993-11-01 00:00:00

abstract：:Alpha-fetoprotein (AFP) is a major serum glycoprotein synthesized during fetal life mainly by the yolk sac and the fetal liver. At term, it reaches high concentrations in the maternal intervillous blood, which is in direct contact with the placental trophoblastic microvillous membrane, and this suggests the placental ...

journal_title：Placenta

authors： Lafuste P,Robert B,Mondon F,Danan JL,Rossi B,Duc-Goiran P,Mignot TM,Nunez EA,Benassayag C,Ferré F

更新日期：2002-09-01 00:00:00

abstract：INTRODUCTION:The aim of this study is to determine whether the gene expression and associated DNA methylation regulation of H19 and IGF2 are altered in placentas conceived by assisted reproductive technologies (ART) compared to natural conceptions. METHODS:113 pregnancies were recruited resulting in 119 placentas (83 ...

journal_title：Placenta

authors： Sakian S,Louie K,Wong EC,Havelock J,Kashyap S,Rowe T,Taylor B,Ma S

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:Pregestational maternal obesity (PGMO) associates with foetoplacental vascular endothelial dysfunction and higher risk for insulin resistance in the neonate. We characterised the PGMO consequences on the insulin response of the human foetoplacental vasculature. METHODS:Umbilical veins were from pregnancies w...

journal_title：Placenta

authors： Villalobos-Labra R,Westermeier F,Pizarro C,Sáez PJ,Toledo F,Pardo F,Kusanovic JP,Mardones F,Poblete JA,Sobrevia L,Farías M

更新日期：2019-10-01 00:00:00