Abstract:
:Maternal and fetal cellular relationships in the normal human term placental basal plate were investigated by single and double immunohistochemical labelling techniques. Extravillous fetal trophoblast in the basal plate was uniformly reactive with markers of low-molecular-weight cytokeratins. The predominant maternal leucocyte population in the basal plate consisted of leucocyte-common-antigen-positive, class II MHC-positive macrophages, which exhibited acid phosphatase activity. Double-labelling methods highlighted the close association of these macrophages with extravillous trophoblast: they often extended processes around the fetal cells and were also observed within islands of cytotrophoblast. Other leucocytes were uncommon, although aggregates of T cells were apparent in some tissues.
journal_name
Placentajournal_title
Placentaauthors
Bulmer JN,Smith J,Morrison L,Wells Mdoi
10.1016/0143-4004(88)90031-8subject
Has Abstractpub_date
1988-05-01 00:00:00pages
237-46issue
3eissn
0143-4004issn
1532-3102pii
0143-4004(88)90031-8journal_volume
9pub_type
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