Cryopreservation of placental biopsies for mitochondrial respiratory analysis.

abstract：:Stereological methods were used to test whether or not altitudinal, ethnic and sex differences in birthweight in Bolivia are associated with differences in placental morphology. Estimates of the volumes, surface areas, lengths and diameters of villi and of fetal capillaries were obtained by analysing paraffin sections...

journal_title：Placenta

authors： Jackson MR,Mayhew TM,Haas JD

更新日期：1987-09-01 00:00:00

abstract：:Nitrotyrosine residues (NT), an index of oxidative stress arising from peroxynitrite formation and action, are found in placental vasculature of pregnancies complicated by pre-eclampsia (PE) or pregestational insulin-dependent diabetes mellitus (IDDM). This study correlates conventional placental pathology with NT imm...

journal_title：Placenta

authors： Stanek J,Eis AL,Myatt L

更新日期：2001-04-01 00:00:00

abstract：:An area of the fetal membranes, within the rupture tear after spontaneous delivery at term, exhibits altered morphology compared to more distal sites. It is characterized by marked swelling of the amniotic and chorionic connective tissue layers, consistent with structural weakness, and a marked reduction of the thickn...

journal_title：Placenta

authors： McParland PC,Taylor DJ,Bell SC

更新日期：2000-01-01 00:00:00

abstract：:The placenta is composed of the amnion, chorionic plate, villous and smooth chorion, decidua basalis, and umbilical cord. The amnion is a readily obtainable source of a large number of cells and cell types, including epithelium, mesenchyme, and endothelium, and is thus an allogeneic resource for regenerative medicine....

journal_title：Placenta

authors： Umezawa A,Hasegawa A,Inoue M,Tanuma-Takahashi A,Kajiwara K,Makino H,Chikazawa E,Okamoto A

更新日期：2019-09-01 00:00:00

abstract：INTRODUCTION:The ratio of birthweight to placental weight (BW:PW) is often used as a measure of placental efficiency in humans and animals. However, ratios have properties that are known to lead to spurious results. An alternative approach is the use of residuals from regression, which reflect whether birthweight is hi...

journal_title：Placenta

authors： Christians JK,Grynspan D,Greenwood SL,Dilworth MR

更新日期：2018-08-01 00:00:00

abstract：:Paracellular pathways in the haemotrichorial placenta of the rat were studied by electron microscopy using lanthanum hydroxide as an electron dense marker. Near term placentae were dually perfused in situ, adding lanthanum to the fetal perfusate. In some placentae outflow pressure on the fetal side was elevated (betwe...

journal_title：Placenta

authors： Kertschanska S,Stulcová B,Kaufmann P,Stulc J

更新日期：2000-09-01 00:00:00

abstract：:The possible roles of the allantoic sac in metabolism of uteroferrin, the iron-containing, purple phosphatase, were examined. This protein, which originates in the maternal endometrium, was measured in allantoic fluid by a specific double-antibody radioimmunoassay and by its beta-mercaptoethanol-activated acid phospha...

journal_title：Placenta

authors： Buhi WC,Ducsay CA,Bartol FF,Bazer FW,Roberts RM

更新日期：1983-01-01 00:00:00

abstract：:We developed a model of maternal hyperglycaemia with secondary hyperinsulinaemia and hypoaminoacidaemia in pregnant sheep (H) to determine the effect of these conditions on uterine, uteroplacental and fetal amino-acid uptake rates and fetal amino-acid concentrations [AA]. Results were compared with normal pregnant ewe...

journal_title：Placenta

authors： Thureen PJ,Padbury JF,Hay WW Jr

更新日期：2001-02-01 00:00:00

abstract：INTRODUCTION:Preterm birth is a heterogeneous phenotype, with placental abnormalities underlying many cases. The etiology of preterm births that occur in the absence of placental abnormalities, however, remain enigmatic and we considered that early pregnancy biomarkers may provide clues. METHODS:Women from a hospital-...

journal_title：Placenta

authors： Sun B,Parks WT,Simhan HN,Bertolet M,Catov JM

更新日期：2020-01-01 00:00:00

abstract：:The morphometric oxygen diffusive conductance (D(p)) of the placenta provides a measure of the efficiency of oxygen transfer between the mother and the developing fetus. Any change in the D(p)may point towards possible adaptation in the light of altered oxygen transfer. Placentae from normal (n=40) and small for gesta...

journal_title：Placenta

authors： Ansari T,Fenlon S,Pasha S,O'Neill B,Gillan JE,Green CJ,Sibbons PD

更新日期：2003-07-01 00:00:00

abstract：:Approximately 6 per cent of placentae of babies admitted to a special care paediatric unit show evidence of peripheral villous stem branch oedema. In more than half of these cases there is evidence of fibrinous vasculosis (FV) in truncal veins. The affected placentae are generally thick and of small diameter, often of...

journal_title：Placenta

authors： Scott JM

更新日期：1983-01-01 00:00:00

abstract：:Receptors for complexes between alpha 2-macroglobulin (alpha 2M) and proteinases (e.g. trypsin) were identified and characterized in the human placenta. The receptors also bound the complex formed between pregnancy zone protein (PZP) and chymotrypsin, although with slightly lower affinity, whereas binding of alpha 2M ...

journal_title：Placenta

authors： Jensen PH,Moestrup SK,Sottrup-Jensen L,Petersen CM,Gliemann J

更新日期：1988-09-01 00:00:00

abstract：:Previous clinical studies have shown the efficacy of a two-stage surgical procedure - the induced membrane (IM) technique - for reconstruction of large bone defects or bone non-union. The first stage involves radical debridement and insertion of a cement spacer into the bone defect. The second stage, performed weeks t...

journal_title：Placenta

authors： Gindraux F,Rondot T,de Billy B,Zwetyenga N,Fricain JC,Pagnon A,Obert L

更新日期：2017-11-01 00:00:00

abstract：:The uptake of [3H]choline and its conversion to [3H]acetylcholine were investigated in term human placental tissue in vitro. Although the net uptake of [3H]choline increased throughout a 45 min incubation period, intracellular [3H]choline levels reach a plateau after 2 min. There was a constant increase in [3H]acetylc...

journal_title：Placenta

authors： Leventer SM,Rowell PP

更新日期：1984-05-01 00:00:00

abstract：:Human placental tissues have been shown to contain gonadotrophin-releasing hormone-(GnRH)-like activity. Thus, the effect of a potent GnRH antagonist (N-Ac-Pro1,D-p-Cl-Phe2,D-Nal(2)3,6-GnRH, obtained from Syntex Laboratories) on placental hormonal release was studied. Explant cultures of placentae of 6 to 15 weeks' ge...

journal_title：Placenta

authors： Siler-Khodr TM,Khodr GS,Rhode J,Vickery BH,Nestor JJ Jr

更新日期：1987-01-01 00:00:00

abstract：:This study was conducted to investigate the association between uterine artery Doppler flow patterns and uteroplacental vascular pathology in normal and complicated pregnancies in view of the recently described concept of heterogeneous causes of hypertensive pregnancy complications. Forty-three women whose pregnancies...

journal_title：Placenta

authors： Aardema MW,Oosterhof H,Timmer A,van Rooy I,Aarnoudse JG

更新日期：2001-05-01 00:00:00

abstract：:The umbilical cord (UC) connects the fetal blood supply to the placenta, so is exposed to all systemic endo- and xenobiotics. We have extensive experience using UC as an analytical matrix for detecting and/or quantitating drugs, chemicals and endogenous compounds. This technical note describes advantages (large amount...

journal_title：Placenta

authors： Price HR,Chehroudi C,Knight SJ,Smith AD,Lai D,Kim H,Wright TE,Coughtrie MW,Collier AC

更新日期：2020-01-15 00:00:00

abstract：:ED(27) trophoblast-like cells were prepared from human chorionic villus samples obtained at 9 weeks gestation and have been grown continuously in vitro without phenotypic drift for nearly a decade. These cells express many trophoblast markers, including cytokeratin, placental alkaline phosphatase (PLAP), secretion of ...

journal_title：Placenta

authors： Kniss DA,Xie Y,Li Y,Kumar S,Linton EA,Cohen P,Fan-Havard P,Redman CW,Sargent IL

更新日期：2002-01-01 00:00:00

abstract：:Anandamide (AEA) and 2-arachidonoylglycerol (2-AG) were the first endocannabinoids to be characterized, that bind two G protein-coupled receptors, CB1 and CB2. AEA synthesized by multiple pathways, including NAPE-specific phospholipase D (NAPE-PLD) and degraded by the fatty acid amide hydrolase (FAAH). AEA levels are ...

journal_title：Placenta

authors： Trabucco E,Acone G,Marenna A,Pierantoni R,Cacciola G,Chioccarelli T,Mackie K,Fasano S,Colacurci N,Meccariello R,Cobellis G,Cobellis L

更新日期：2009-06-01 00:00:00

abstract：INTRODUCTION:Research suggests that autism spectrum disorder (ASD) has its origins in utero. This study examines the association between evidence of placental histopathology and ASD. METHODS:Administrative claims data and medical records data were used to identify ASD cases (N = 55) and matched controls (N = 199) born...

journal_title：Placenta

authors： Straughen JK,Misra DP,Divine G,Shah R,Perez G,VanHorn S,Onbreyt V,Dygulska B,Schmitt R,Lederman S,Narula P,Salafia CM

更新日期：2017-09-01 00:00:00

abstract：INTRODUCTION:The objective of this study was to explore serum levels of differentially abundant proteins between women with hypertensive disorders of pregnancy (HDP) and women with normal-term pregnancy, and to explore the contribution of SH3BGRL3 to the pathogenesis of HDP. METHODS:At 6-20 weeks gestation 48 pregnant...

journal_title：Placenta

authors： Jiang M,Lash GE,Zeng S,Liu F,Han M,Long Y,Cai M,Hou H,Ning F,Hu Y,Yang H

更新日期：2020-11-14 00:00:00

abstract：:Placental ultrasonographic, bio- and histochemical studies were performed on four unrelated fetuses affected with Niemann-Pick disease Type A, following prostaglandin-induced abortion at about the 19th week of gestation. An accumulation of sphingomyelin in the placentae of affected fetuses indicates the essential role...

journal_title：Placenta

authors： Schoenfeld A,Abramovici A,Klibanski C,Ovadia J

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:Pregestational maternal obesity (PGMO) associates with foetoplacental vascular endothelial dysfunction and higher risk for insulin resistance in the neonate. We characterised the PGMO consequences on the insulin response of the human foetoplacental vasculature. METHODS:Umbilical veins were from pregnancies w...

journal_title：Placenta

authors： Villalobos-Labra R,Westermeier F,Pizarro C,Sáez PJ,Toledo F,Pardo F,Kusanovic JP,Mardones F,Poblete JA,Sobrevia L,Farías M

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Visualization of the retroplacental clear space (RPCS) may provide critical insight into the development of abnormally invasive placenta (AIP). In this pre-clinical study, we characterized the appearance of the RPCS on magnetic resonance imaging (MRI) during the second half of gestation using a liposomal g...

journal_title：Placenta

authors： Badachhape AA,Kumar A,Ghaghada KB,Stupin IV,Srivastava M,Devkota L,Starosolski Z,Tanifum EA,George V,Fox KA,Yallampalli C,Annapragada AV

更新日期：2019-02-01 00:00:00

abstract：:Eleven placentae and one fibroblast cell culture from pregnancies complicated by various inherited metabolic disorders, together with five chorionic villus biopsies from pregnancies at risk, were examined for ultrastructural evidence of accumulation of metabolites. Abnormal ultrastructural features were present as ear...

journal_title：Placenta

authors： Jones CJ,Lendon M,Chawner LE,Jauniaux E

更新日期：1990-09-01 00:00:00

abstract：:Maternal diabetes affects the development of the offspring by altering the uterine environment. We aimed to investigate the extent to which the blood flow (measured as Tissue Perfusion Units; TPU) to implantation sites and the expression of developmentally important genes in the offspring are affected by maternal diab...

journal_title：Placenta

authors： Zabihi S,Wentzel P,Eriksson UJ

更新日期：2008-05-01 00:00:00

abstract：:We tested the hypothesis that the expression of placental connective tissue growth factor (CTGF) is enhanced in pregnancies complicated by severe preeclampsia (PE) or fetal growth restriction (FGR). CTGF expression was analyzed using immunostaining, western blot and real-time quantitative PCR in placental samples obta...

journal_title：Placenta

authors： Oh SY,Song SE,Seo ES,Kim KH,Choi SJ,Suh YL,Sadovsky Y,Roh CR

更新日期：2009-11-01 00:00:00

abstract：:Combined staining of non-cultured interphase nuclei from hydatidiform moles with distamycin A and DAPI resulted in the presence of specific stained interphase bodies. A mean number of six interphase bodies was observed in moles with a diploid karyotype and a mean number of nine interphase bodies was observed in triplo...

journal_title：Placenta

authors： Tommerup N,Vejerslev LO

更新日期：1985-07-01 00:00:00

abstract：:Pregnancy-associated placental protein-A (PAPP-A), first isolated from maternal serum, has been identified as a metalloprotease cleaving insulin-like growth factor binding protein-4 (IGFBP-4). The source of PAPP-A during pregnancy is unclear. We therefore investigated PAPP-A expression during in vitro human villous cy...

journal_title：Placenta

authors： Guibourdenche J,Frendo JL,Pidoux G,Bertin G,Luton D,Muller F,Porquet D,Evain-Brion D

更新日期：2003-05-01 00:00:00

abstract：:Intrauterine growth and development can impact upon the long-term health of an individual. The fetus is dependent upon the placenta for its supply of nutrients and oxygen from the mother. In turn, the functional capacity of the placenta to supply that demand is under the control of the fetal and maternal genomes. Rece...

journal_title：Placenta

authors： Angiolini E,Fowden A,Coan P,Sandovici I,Smith P,Dean W,Burton G,Tycko B,Reik W,Sibley C,Constância M

更新日期：2006-04-01 00:00:00