Amnion-derived cells as a reliable resource for next-generation regenerative medicine.

Abstract:

:The placenta is composed of the amnion, chorionic plate, villous and smooth chorion, decidua basalis, and umbilical cord. The amnion is a readily obtainable source of a large number of cells and cell types, including epithelium, mesenchyme, and endothelium, and is thus an allogeneic resource for regenerative medicine. Endothelial cells are obtained from large arteries and veins in the amniotic membrane as well as the umbilical cord. The amnion-derived cells exhibit transdifferentiation capabilities, including chondrogenesis and cardiomyogenesis, by introduction of transcription factors, in addition to their original and potential phenotypes. The amnion is also a source for production of induced pluripotent stem cells (AM-iPSCs). The AM-iPSCs exhibit stable phenotypes, such as multipotency and immortality, and a unique gene expression pattern. Through the use of amnion-derived cells, as well as other placenta-derived cells, preclinical proof of concept has been achieved in a mouse model of muscular dystrophy.

journal_name

Placenta

journal_title

Placenta

authors

Umezawa A,Hasegawa A,Inoue M,Tanuma-Takahashi A,Kajiwara K,Makino H,Chikazawa E,Okamoto A

doi

10.1016/j.placenta.2019.06.381

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

50-56

eissn

0143-4004

issn

1532-3102

pii

S0143-4004(19)30027-X

journal_volume

84

pub_type

杂志文章,评审

相关文献

PLACENTA文献大全
  • Placenta-bound and body fluid PP13 and its mRNA in normal pregnancy compared to preeclampsia, HELLP and preterm delivery.

    abstract:OBJECTIVES:To compare the distribution of placental protein 13 (PP13) in fetal and maternal blood and amnionic fluid and to correlate it with PP13 protein and mRNA in the placenta. METHODS:Umbilical arterial serum, amnionic fluid, maternal venous serum and placental tissues were collected from normal outcome pregnanci...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2010.09.006

    authors: Sammar M,Nisemblat S,Fleischfarb Z,Golan A,Sadan O,Meiri H,Huppertz B,Gonen R

    更新日期:2011-02-01 00:00:00

  • Placental involvement in glycogen storage disease type IV.

    abstract::Glycogen storage disease type IV (GSD IV) is a rare autosomal recessive disorder caused by glycogen branching enzyme (GBE) deficiency and resulting in the storage of abnormal glycogen (polyglucosan). Prenatal diagnosis is based on biochemical assay of GBE activity or on mutation analysis, but polyglucosan can also be ...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2008.01.005

    authors: Konstantinidou AE,Anninos H,Dertinger S,Nonni A,Petersen M,Karadimas C,Havaki S,Marinos E,Akman HO,DiMauro S,Patsouris E

    更新日期:2008-04-01 00:00:00

  • Transplacental lactate dehydrogenase-elevating virus (LDV) transmission: immune inhibition of umbilical cord infection, and correlation of fetal virus susceptibility with development of F4/80 antigen expression.

    abstract::Maternal-to-fetal transmission of the murine lactate dehydrogenase-elevating virus (LDV) has been previously shown to be regulated by maternal immunity as well as gestational age. For the present study, the role of maternal immunity in placental and umbilical cord virus protection was studied, and virus targeting of u...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1053/plac.2002.0829

    authors: Zitterkopf NL,Haven TR,Huela M,Bradley DS,Cafruny WA

    更新日期:2002-05-01 00:00:00

  • Placental morphology: from molecule to mother -- a dedication to Peter Kaufmann -- a review.

    abstract::Theories on the development of placental pathologies and insufficiencies are based on the assumption that the development of the placental villous trees, the invasion of extravillous trophoblast or the differentiation of the villous trophoblast is somehow dysregulated. One of the pioneers trying to answer these questi...

    journal_title:Placenta

    pub_type: 传,历史文章,杂志文章,评审

    doi:10.1016/j.placenta.2006.01.007

    authors: Huppertz B,Burton G,Cross JC,Kingdom JC

    更新日期:2006-04-01 00:00:00

  • Purification and partial characterization of peroxidase from human term placenta of non-smokers: metabolism of benzo(a)pyrene-7, 8-dihydrodiol.

    abstract::Peroxidase (Donor: H(2)O(2)oxidoreductase EC 1.11.1.7) from human term placentae of non-smokers was purified to homogeneity by a combination of NH(4)Cl extraction, affinity chromatography, (NH(4))(2)SO(4)precipitation, ion-exchange and gel filtration chromatography. The homogeneity of purified human placental peroxida...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1053/plac.2000.0537

    authors: Madhavan ND,Naidu KA

    更新日期:2000-07-01 00:00:00

  • Disrupted compensatory response mediated by Wolfram syndrome 1 protein and corticotrophin-releasing hormone family peptides in early-onset intrahepatic cholestasis pregnancy.

    abstract:INTRODUCTION:The most adverse perinatal outcome of intrahepatic cholestasis of pregnancy (ICP) is sudden fetal death related to acute fetoplacental hypoxia. Corticotrophin-releasing hormone (CRH), urocortin (UCN), and Wolfram syndrome 1 (WFS1) proteins may have a compensatory response to hypoxic stress. METHODS:A tota...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2019.06.378

    authors: Xu T,Zhou Z,Liu N,Deng C,Huang G,Zhou F,Liu X,Wang X

    更新日期:2019-08-01 00:00:00

  • Placental release of distinct DNA-associated micro-particles into maternal circulation: reflective of gestation time and preeclampsia.

    abstract:BACKGROUND:The aim of this study was to determine whether DNA-associated micro-particles (MPs) in maternal plasma express fetal-derived human leukocyte antigen-G (HLA-G) or placental alkaline phosphatase (PLAP) and whether the levels differ between women with normotensive pregnancies and preeclampsia. METHODS:DNA-asso...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2009.06.012

    authors: Orozco AF,Jorgez CJ,Ramos-Perez WD,Popek EJ,Yu X,Kozinetz CA,Bischoff FZ,Lewis DE

    更新日期:2009-10-01 00:00:00

  • Three-dimensional ultrasound measurement of the placental volume in early pregnancy: method and correlation with biochemical placenta parameters.

    abstract::Placental size has been an interesting topic of research for many years. The main aim of this study was to investigate the feasibility of measuring the placental volume at the end of the first trimester using three-dimensional (3D) ultrasound and to correlate these volumes to known placental functional indices and to ...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1053/plac.2001.0684

    authors: Metzenbauer M,Hafner E,Hoefinger D,Schuchter K,Stangl G,Ogris E,Philipp K

    更新日期:2001-07-01 00:00:00

  • The function of miR-519d in cell migration, invasion, and proliferation suggests a role in early placentation.

    abstract::The processes of proliferation, migration, and invasion of extravillous trophoblasts are critical for placental implantation and early development, and directly influence pregnancy outcome. Dysregulation of these processes has been associated with placental dysfunction, implicated in clinical conditions such as preecl...

    journal_title:Placenta

    pub_type: 杂志文章,评审

    doi:10.1016/j.placenta.2016.10.004

    authors: Xie L,Sadovsky Y

    更新日期:2016-12-01 00:00:00

  • Corticosteroid metabolism in vitro by human placenta, fetal membranes and decidua in early and late gestation.

    abstract::Corticosteroid conversion by early (7 to 10 weeks) and late (36 to 42 weeks) human placenta, fetal membranes and decidua was studied. Tritiated cortisol, cortisone, corticosterone, 11-dehydrocorticosterone (DHC) and 11-deoxycorticosterone (DOC) were incubated in vitro with homogenates of these tissues and extracts chr...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/s0143-4004(81)80025-2

    authors: López Bernal A,Craft IL

    更新日期:1981-10-01 00:00:00

  • Altered maternal and placental lipid metabolism and fetal fat development in obesity: Current knowledge and advances in non-invasive assessment.

    abstract::Abnormal maternal lipid profiles, a hallmark of increased maternal adiposity, are associated with pregnancy complications such as preeclampsia and gestational diabetes, and offspring long-term metabolic health is impacted as the consequence of altered fetal growth, physiology and often iatrogenic prematurity. The meta...

    journal_title:Placenta

    pub_type: 杂志文章,评审

    doi:10.1016/j.placenta.2018.05.011

    authors: Delhaes F,Giza SA,Koreman T,Eastabrook G,McKenzie CA,Bedell S,Regnault TRH,de Vrijer B

    更新日期:2018-09-01 00:00:00

  • Maternal uterine artery VEGF gene therapy for treatment of intrauterine growth restriction.

    abstract::Intrauterine growth restriction (IUGR) is a serious pregnancy complication affecting approximately 8% of all pregnancies. The aetiology is believed to be insufficient maternal uteroplacental perfusion which prevents adequate nutrient and oxygen availability for the fetus. There is no treatment that can improve uteropl...

    journal_title:Placenta

    pub_type: 杂志文章,评审

    doi:10.1016/j.placenta.2017.09.011

    authors: David AL

    更新日期:2017-11-01 00:00:00

  • Role of low placental share in twin-twin transfusion syndrome complicated by intrauterine growth restriction.

    abstract:OBJECTIVES:Prior studies have demonstrated that donor twin survival following treatment of twin-twin transfusion syndrome (TTTS) was highly associated with donor intrauterine growth restriction (IUGR). Here, we hypothesized that donor IUGR may be attributed in part to low placental share. STUDY DESIGN:The study popula...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2011.05.009

    authors: Grubbs BH,Benirschke K,Korst LM,Llanes A,Yedigarova L,Chmait RH

    更新日期:2011-08-01 00:00:00

  • Receptors for oestradiol in human placenta.

    abstract::The binding of oestradiol in human placental tissue obtained from spontaneous and caesarean deliveries was investigated. Villous tissue was homogenized and the 800 g 'cytosol' supernatant treated with ammonium sulphate. The precipitate was redissolved and the preparation then equilibrated with [3H]oestradiol. After se...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/s0143-4004(85)80015-1

    authors: Laminski NA,Hammond KD

    更新日期:1985-09-01 00:00:00

  • The role of placental breast cancer resistance protein in the efflux of glyburide across the human placenta.

    abstract::Gestational diabetes mellitus is a common medical complication in pregnancy. Recent findings demonstrate that glyburide is effluxed against a concentration gradient from the fetal to the maternal circulation. However, the transport systems involved in the active efflux of glyburide in the human placenta have not yet b...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2008.05.001

    authors: Pollex E,Lubetsky A,Koren G

    更新日期:2008-08-01 00:00:00

  • Long-chain polyunsaturated fatty acid transport across human placental choriocarcinoma (BeWo) cells.

    abstract::Long-chain polyunsaturated fatty acids (LCPUFAs) such as docosahexaenoic acid (DHA) and arachidonic acid (AA) are essential for proper development of fetal brain and retina. These LCPUFAs are selectively enriched in the fetal circulation compared with the maternal circulation. In the current study we investigated the ...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2008.10.007

    authors: Tobin KA,Johnsen GM,Staff AC,Duttaroy AK

    更新日期:2009-01-01 00:00:00

  • The effect of ceruloplasmin on iron release from placental (BeWo) cells; evidence for an endogenous Cu oxidase.

    abstract::The mechanism of iron release from the placenta into the fetal circulation is not well understood. Ceruloplasmin, a plasma ferroxidase, has been implicated in iron efflux from a variety of cell types. The hypothesis is that circulating ceruloplasmin facilitates iron efflux by oxidizing the released Fe(II) to Fe(III) f...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1053/plac.2000.0582

    authors: Danzeisen R,Ponnambalam S,Lea RG,Page K,Gambling L,McArdle HJ

    更新日期:2000-11-01 00:00:00

  • Bovine placental steroid sulphatase: molecular cloning and expression pattern in placentomes during gestation and at parturition.

    abstract::Apart from during the prepartal period, the main oestrogen produced by the bovine trophoblast is oestrone sulphate (E1S) which does not bind to nuclear oestrogen receptors (ER). High steroid sulphatase (StS) activities previously detected in the maternal part of bovine placentomes (caruncles) suggest the local activat...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2007.01.008

    authors: Greven H,Kowalewski MP,Hoffmann B,Geyer J,Rex-Haffner M,Ugele B,Schuler G

    更新日期:2007-08-01 00:00:00

  • RANKL promotes the growth of decidual stromal cells in an autocrine manner via CCL2/CCR2 interaction in human early pregnancy.

    abstract:OBJECTIVE:Receptor-activator of NF-κB ligand (TNFSF11, also known as RANKL) and its receptor RANK are essential regulators on bone remodeling, mammary gland development and hormone-associated breast cancer development. However, the expression pattern and role of RANKL/RANK axis in decidual stromal cells (DSCs) are uncl...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2013.04.020

    authors: Meng YH,Li H,Chen X,Liu LB,Shao J,Chang KK,Du MR,Jin LP,Li MQ,Li DJ

    更新日期:2013-08-01 00:00:00

  • Nitric oxide synthase activity in placentae from women with pre-eclampsia.

    abstract::The syncytiotrophoblast (ST) cell layer of the human villous placenta expresses nitric oxide (NO) synthase. Because NO is a potent relaxant of vascular smooth muscle and inhibitor of platelet activity, we postulated that exaggerated intervillous aggregation of platelets and reduced fetoplacental blood flow in pre-ecla...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/0143-4004(95)90013-6

    authors: Conrad KP,Davis AK

    更新日期:1995-12-01 00:00:00

  • Placental magnetic resonance imaging in chronic hypertension: A case-control study.

    abstract:INTRODUCTION:We aimed to explore the use of magnetic resonance imaging (MRI) in vivo as a tool to elucidate the placental phenotype in women with chronic hypertension. METHODS:In case-control study, women with chronic hypertension and those with uncomplicated pregnancies were imaged using either a 3T Achieva or 1.5T I...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2020.12.006

    authors: Ho A,Hutter J,Slator P,Jackson L,Seed PT,Mccabe L,Al-Adnani M,Marnerides A,George S,Story L,Hajnal JV,Rutherford M,Chappell LC

    更新日期:2020-12-13 00:00:00

  • The chemokine connection: hormonal and embryonic regulation at the human maternal-embryonic interface--a review.

    abstract::Chemokines are small polypeptides that attract specific leukocyte subsets by binding to cell-surface receptors. In reproductive biology, they have been implicated in ovulation, menstruation, and embryo implantation, and pathological processes such as preterm delivery, HIV infection, and endometriosis. It is known that...

    journal_title:Placenta

    pub_type: 杂志文章,评审

    doi:10.1016/s0143-4004(03)00134-6

    authors: Dominguez F,Pellicer A,Simon C

    更新日期:2003-10-01 00:00:00

  • Multiscale three-dimensional imaging of the placenta.

    abstract::Placental function involves multiple different processes which operate at different scales from centimetres to nanometres. Everything that the placenta does from mediating blood flow to gene expression, occurs within a three-dimensional anatomical framework. This review outlines how multiscale three-dimensional imagin...

    journal_title:Placenta

    pub_type: 杂志文章,评审

    doi:10.1016/j.placenta.2020.01.016

    authors: Lewis RM,Pearson-Farr JE

    更新日期:2020-12-01 00:00:00

  • A new method for measurement of placental elasticity: acoustic radiation force impulse imaging.

    abstract:INTRODUCTION:The velocities of the lateral shear waves (Vs; m s⁻¹) generated by an acoustic radiation force impulse (ARFI) correlate with Young's modulus. Therefore, ARFI can be used as a new method to evaluate tissue elasticity. The aim of this study was to investigate the safety of ARFI imaging and the differences in...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2013.08.014

    authors: Sugitani M,Fujita Y,Yumoto Y,Fukushima K,Takeuchi T,Shimokawa M,Kato K

    更新日期:2013-11-01 00:00:00

  • Polyploidization in the trophoblast and uterine glandular epithelium of the endotheliochorial placenta of silver fox (Vulpes fulvus Desm.), as revealed by the DNA content.

    abstract::Dynamics of genome multiplication during establishment of interrelations between trophoblast and glandular epithelium of the endometrium has been studied in the course of formation of placenta in the silver fox. During formation of the placenta, penetration of the trophoblast into the zone of the endometrial glandular...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1053/plac.2001.0675

    authors: Zybina TG,Zybina EV,Kiknadze II,Zhelezova AI

    更新日期:2001-05-01 00:00:00

  • Leptin expression in the fetus and placenta during mouse pregnancy.

    abstract::During pregnancy, leptin concentrations in the maternal circulation are elevated in both humans and rodents but decrease to pre-pregnancy levels at birth, suggesting a role for leptin in the maintenance of pregnancy. Synthesis of leptin by the human placenta is established but whether the murine placenta synthesizes l...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2004.03.009

    authors: Malik NM,Carter ND,Wilson CA,Scaramuzzi RJ,Stock MJ,Murray JF

    更新日期:2005-01-01 00:00:00

  • Placental expression of vascular endothelial growth factor in placentae from pregnancies complicated by pre-eclampsia and intrauterine growth restriction does not support placental hypoxia at delivery.

    abstract::In view of the pathological placental features of pre-eclampsia and intrauterine growth restriction (IUGR), and the angiogenic effects of vascular endothelial growth factor (VEGF), the aim of this study was to determine the expression of VEGF in placentae from normal pregnancies and to compare the results with placent...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/s0143-4004(97)80061-6

    authors: Lyall F,Young A,Boswell F,Kingdom JC,Greer IA

    更新日期:1997-05-01 00:00:00

  • Differential host response to LPS variants in amniochorion and the TLR4/MD-2 system in Macaca nemestrina.

    abstract:OBJECTIVES:Microbial-specific factors are likely critical in determining whether bacteria trigger preterm labor. Structural variations in lipopolysaccharide (LPS), a component of gram-negative bacteria, can determine whether LPS has an inflammatory (agonist) or anti-inflammatory (antagonist) effect through Toll-like re...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2010.06.010

    authors: Chang J,Jain S,Carl DJ,Paolella L,Darveau RP,Gravett MG,Adams Waldorf KM

    更新日期:2010-09-01 00:00:00

  • Evidence for the functional activity of hypoxia-inducible transcription factors overexpressed in preeclamptic placentae.

    abstract::Placentas from women with preeclampsia overexpress the hypoxia-inducible transcription factor proteins, HIF-1alpha and -2alpha (Rajakumar 2001, Biol Reprod 64; p499-506 and p1019-1020). As a first step in evaluating whether HIF-alpha overexpressed in preeclamptic placentae is capable of transactivation, we tested its ...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2004.02.011

    authors: Rajakumar A,Brandon HM,Daftary A,Ness R,Conrad KP

    更新日期:2004-11-01 00:00:00

  • All-trans-retinoic acid regulates aquaporin-3 expression and related cellular membrane permeability in the human amniotic environment.

    abstract:INTRODUCTION:The aquaporins (AQP1, 3, 8, 9 and 11) are known to be expressed, and involved in the transport of water and small molecules through fetal membranes. To exert these crucial functions, these AQPs have to be finely regulated. All-trans-retinoic acid (atRA) was previously found to regulate some genes in this e...

    journal_title:Placenta

    pub_type: 杂志文章

    doi:10.1016/j.placenta.2015.05.010

    authors: Prat C,Bouvier D,Comptour A,Marceau G,Belville C,Clairefond G,Blanc P,Gallot D,Blanchon L,Sapin V

    更新日期:2015-08-01 00:00:00