Abstract:
:The nucleotide sequence of the dnaK operon cloned from Porphyromonas gingivalis revealed that the operon does not contain homologues of either dnaJ or grpE. However, there were two genes which encode small heat shock proteins immediately downstream from the dnaK and they were transcribed together with dnaK as one unit. The ATPase activity of the P. gingivalis DnaK was synergistically stimulated up to 40-fold in the simultaneous presence of Escherichia coli DnaJ and GrpE. These results suggest that the DnaK homologue of P. gingivalis, with its unique genetic structure and evolutionary features, works as a member of the DnaK chaperone system.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Yoshida A,Nakano Y,Yamashita Y,Oho T,Shibata Y,Ohishi M,Koga Tdoi
10.1016/s0014-5793(99)00237-9keywords:
subject
Has Abstractpub_date
1999-03-12 00:00:00pages
287-91issue
2-3eissn
0014-5793issn
1873-3468pii
S0014-5793(99)00237-9journal_volume
446pub_type
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