Abstract:
:Social group dynamics are highly complex. In this issue of Neuron, Anpilov et al. use a novel wireless optogenetic device to demonstrate that the repeated stimulation of oxytocin neurons modulates pro-social and agonistic behaviors in a time- and context-dependent manner.
journal_name
Neuronjournal_title
Neuronauthors
Maltese F,Papaleo Fdoi
10.1016/j.neuron.2020.07.027subject
Has Abstractpub_date
2020-08-19 00:00:00pages
591-593issue
4eissn
0896-6273issn
1097-4199pii
S0896-6273(20)30571-7journal_volume
107pub_type
评论,杂志文章相关文献
NEURON文献大全abstract::We describe the extent to which presynaptic structures at the embryonic neuromuscular junction of Drosophila can form in mutants where development of postsynaptic somatic muscles is affected. Although twist mutant embryos lack mesoderm, motor axons still grow out of the CNS and form morphologically normal presynaptic ...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(00)80195-6
更新日期:1996-10-01 00:00:00
abstract::Antibodies were raised to three portions of the predicted sequences of Shaker, a gene that encodes a family of K+ channel components that are produced by the alternative splicing of transcripts. On immunoblots, the protein products appear to be 65,000-85,000 daltons in size. No smaller products were detected. Immunocy...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/0896-6273(90)90448-o
更新日期:1990-01-01 00:00:00
abstract::The rhodopsin regulatory protein, visual arrestin, undergoes light-dependent trafficking in mammalian and Drosophila photoreceptor cells, though the mechanisms underlying these movements are poorly understood. In Drosophila, the movement of the visual arrestin, Arr2, functions in long-term adaptation and is dependent ...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2004.06.014
更新日期:2004-07-08 00:00:00
abstract::During the metamorphosis of the Xenopus laevis retina, thyroid hormone (TH) preferentially induces ventral ciliary marginal zone (CMZ) cells to both increase their proliferation and give rise to ipsilaterally projecting ganglion cells. Here we show that dorsal CMZ cells express type III deiodinase (D3), an enzyme that...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(00)81034-x
更新日期:1999-12-01 00:00:00
abstract::Rhythmic spontaneous electrical activity occurs in many parts of the developing nervous system, where it plays essential roles in the refinement of neural connections. By blocking or slowing this bursting activity, via in ovo drug applications at precise developmental periods, we show that such activity is also requir...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2004.08.018
更新日期:2004-09-02 00:00:00
abstract::Many animals guide their movements using optic flow, the displacement of stationary objects across the retina caused by self-motion. How do animals selectively synthesize a global motion pattern from its local motion components? To what extent does this feature selectivity rely on circuit mechanisms versus dendritic p...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2018.08.022
更新日期:2018-10-10 00:00:00
abstract::The intraparietal cortex is involved in the control of visually guided actions, like reach-to-grasp movements, which require extracting the 3D shape and position of objects from 2D retinal images. Using fMRI in behaving monkeys, we investigated the role of the intraparietal cortex in processing stereoscopic informatio...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2007.06.040
更新日期:2007-08-02 00:00:00
abstract::The visual cortex has the capacity for experience-dependent change, or cortical plasticity, that is retained throughout life. Plasticity is invoked for encoding information during perceptual learning, by internally representing the regularities of the visual environment, which is useful for facilitating intermediate-l...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2012.06.030
更新日期:2012-07-26 00:00:00
abstract::A meta-analysis of non-human primates performing three different tasks (Object-Match, Category-Match, and Category-Saccade associations) revealed signatures of explicit and implicit learning. Performance improved equally following correct and error trials in the Match (explicit) tasks, but it improved more after corre...
journal_title:Neuron
pub_type: 杂志文章,meta分析
doi:10.1016/j.neuron.2017.09.032
更新日期:2017-10-11 00:00:00
abstract::The p75 neurotrophin receptor (p75NTR) collaborates with the Nogo receptor (NgR) and LINGO-1 to activate RhoA in response to myelin-based growth inhibitors such as myelin-associated glycoprotein (MAG). In this issue of Neuron, Domeniconi et al., in a surprising turn, show that MAG induces intramembrane proteolysis (RI...
journal_title:Neuron
pub_type: 评论,杂志文章
doi:10.1016/j.neuron.2005.06.002
更新日期:2005-06-16 00:00:00
abstract::Using high resolution capacitance measurements, we have characterized an ultrafast component of transmitter release in ribbon-type synaptic terminals of retinal bipolar neurons. During depolarization, capacitance increases to a plateau of approximately 30 fF with a time constant of approximately 1.5 ms. When not limit...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(00)80254-8
更新日期:1996-12-01 00:00:00
abstract::Neocortical excitatory and inhibitory neurons derive from distinct progenitor domains during embryonic development and migrate to their final positions, where they assemble into functional circuits. This process appears to be influenced by lineage relationships among locally born excitatory neurons, raising the intrig...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2016.09.034
更新日期:2016-10-05 00:00:00
abstract::Plus end tracking proteins (+TIPS) bind to microtubules. Results reported by Lee et al. and Zhou et al. in this issue of Neuron demonstrate that, via intracellular pathways signaling to +TIPs, microtubules can be a direct target of guidance cues in steering growth cones and regulating axon elongation. ...
journal_title:Neuron
pub_type: 评论,杂志文章
doi:10.1016/j.neuron.2004.06.009
更新日期:2004-06-24 00:00:00
abstract::Activity is known to be important for the refinement of neural connections in the developing brain. In this issue of Neuron, Hanson and Landmesser provide evidence that GABA-dependent spontaneous bursting of motor neurons in the embryonic spinal cord is required for the correct execution of an early axon pathfinding d...
journal_title:Neuron
pub_type: 评论,杂志文章,评审
doi:10.1016/j.neuron.2004.08.027
更新日期:2004-09-02 00:00:00
abstract::Oxytocin (OT) release by axonal terminals onto the central nucleus of the amygdala exerts anxiolysis. To investigate which subpopulation of OT neurons contributes to this effect, we developed a novel method: virus-delivered genetic activity-induced tagging of cell ensembles (vGATE). With the vGATE method, we identifie...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2019.04.029
更新日期:2019-07-03 00:00:00
abstract::Voltage-activated potassium (Kv) channels from mammalian brain are hetero-oligomers containing alpha and beta subunits. Coexpression of Kv1 alpha and Kv beta 1 subunits confers rapid A-type inactivation on noninactivating potassium channels (delayed rectifiers) in expression systems in vitro. We have delineated a Kv1....
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(00)80063-x
更新日期:1996-02-01 00:00:00
abstract::Formation of the normal mammalian cerebral cortex requires the migration of GABAergic inhibitory interneurons from an extracortical origin, the lateral ganglionic eminence (LGE). Mechanisms guiding the migratory direction of these neurons, or other neurons in the neocortex, are not well understood. We have used an exp...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(00)80801-6
更新日期:1999-07-01 00:00:00
abstract::Calcium/calmodulin-dependent protein kinase II (CaMKII) has been described as a biochemical switch that is turned on by increases in intracellular calcium to mediate synaptic plasticity. Here, we show that reductions in CaMKII activity trigger persistent increases in intrinsic excitability. In spontaneously firing ves...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2005.04.009
更新日期:2005-05-19 00:00:00
abstract::Sensory input reaching the brain from bilateral and offset channels is nonetheless perceived as unified. This unity could be explained by simultaneous projections to both hemispheres, or inter-hemispheric information transfer between sensory cortical maps. Odor input, however, is not topographically organized, nor doe...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2018.07.012
更新日期:2018-08-22 00:00:00
abstract::The MAG-deficient mouse was used to test whether MAG acts as a significant inhibitor of axonal regeneration in the adult mammalian CNS, as suggested by cell culture experiments. Cell spreading, neurite elongation, or growth cone collapse of different cell types in vitro was not significantly different when myelin prep...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/0896-6273(95)90015-2
更新日期:1995-12-01 00:00:00
abstract::Cysteine string protein alpha (CSPalpha)--an abundant synaptic vesicle protein that contains a DNA-J domain characteristic of Hsp40 chaperones--is thought to regulate Ca2+ channels and/or synaptic vesicle exocytosis. We now show that, in young mice, deletion of CSPalpha does not impair survival and causes no significa...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(04)00190-4
更新日期:2004-04-22 00:00:00
abstract::Experience is a powerful sculptor of developing neural connections. In the primary visual cortex (V1), cortical connections are particularly susceptible to the effects of sensory manipulation during a postnatal critical period. At the molecular level, this activity-dependent plasticity requires the transformation of s...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(02)00966-2
更新日期:2002-10-24 00:00:00
abstract::Two papers in the current issue of Neuron (Izuma et al. and Zink et al.) report that activity in specific regions of the brain, especially the striatum, reflects a common signal of reward in both the economic (e.g., money) and social (e.g., praise and status) domains. ...
journal_title:Neuron
pub_type: 评论,杂志文章
doi:10.1016/j.neuron.2008.04.005
更新日期:2008-04-24 00:00:00
abstract::Using a transgenic mouse line in which GFP is expressed in a single population of retinal ganglion cells (RGCs), Huberman and colleagues report in this issue of Neuron that the axon terminals of RGCs exhibit an orderly pattern of distribution in the higher visual centers. This pattern undergoes a developmental refinem...
journal_title:Neuron
pub_type: 评论,杂志文章
doi:10.1016/j.neuron.2008.08.001
更新日期:2008-08-14 00:00:00
abstract::The molecular specification of central circuits that coordinate expression of innate behaviors in response to specific sensory cues from the environment remains a puzzle. In this issue of Neuron, Choi, Dong, and colleagues used expression profiling and genetic axonal tracing to visualize a hypothalamic point of conver...
journal_title:Neuron
pub_type: 评论,杂志文章
doi:10.1016/j.neuron.2005.05.001
更新日期:2005-05-19 00:00:00
abstract::We utilized the Cre-LoxP system to establish erbB2 conditional mutant mice in order to investigate the role of erbB2 in postnatal development of the enteric nervous system. The erbB2/nestin-Cre conditional mutants exhibit retarded growth, distended colons, and premature death, resembling human Hirschsprung's disease. ...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/s0896-6273(02)01128-5
更新日期:2003-01-09 00:00:00
abstract::L-Glutamate is regarded as the major excitatory neurotransmitter in the mammalian CNS. However, whether the released transmitter originates from a cytosolic pool or is discharged from synaptic vesicles by exocytosis (vesicle hypothesis) remains controversial. A problem with the general acceptance of the vesicle hypoth...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/0896-6273(89)90240-7
更新日期:1989-12-01 00:00:00
abstract::The ERK MAP kinase signaling cascade plays critical roles in brain development, learning, memory, and cognition. It has recently been appreciated that mutation or deletion of elements within this signaling pathway leads to developmental syndromes in humans that are associated with impaired cognitive function and autis...
journal_title:Neuron
pub_type: 杂志文章,评审
doi:10.1016/j.neuron.2009.01.001
更新日期:2009-01-29 00:00:00
abstract::Promises are one of the oldest human-specific psychological mechanisms fostering cooperation and trust. Here, we study the neural underpinnings of promise keeping and promise breaking. Subjects first make a promise decision (promise stage), then they anticipate whether the promise affects the interaction partner's dec...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/j.neuron.2009.11.017
更新日期:2009-12-10 00:00:00
abstract::To learn about the carboxy-terminal extent of amyloid beta-protein (A beta) composition of senile plaques (SPs) in the brain affected with Alzheimer's disease (AD), we employed two end-specific monoclonal antibodies as immunocytochemical probes: one is specific for A beta 40, the carboxyl terminus of A beta 1-40, whil...
journal_title:Neuron
pub_type: 杂志文章
doi:10.1016/0896-6273(94)90458-8
更新日期:1994-07-01 00:00:00