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How early is firing required for wiring?

Abstract：

:Activity is known to be important for the refinement of neural connections in the developing brain. In this issue of Neuron, Hanson and Landmesser provide evidence that GABA-dependent spontaneous bursting of motor neurons in the embryonic spinal cord is required for the correct execution of an early axon pathfinding decision.

journal_name

Neuron

journal_title

Neuron

authors

Goulding M

doi

10.1016/j.neuron.2004.08.027

subject

Has Abstract

pub_date

2004-09-02 00:00:00

pages

601-3

issue

5

eissn

0896-6273

issn

1097-4199

pii

S0896627304005392

journal_volume

43

pub_type

评论,杂志文章,评审

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