The deficiency in nuclear localization signal of Neodiprion lecontei nucleopolyhedrovirus DNA polymerase prevents rescue of viral DNA replication and virus production in dnapol-null Autographa californica multiple nucleopolyhedrovirus.

abstract：:The transforming potential of DNA tumor viruses derives mainly from the ability of their encoded oncogene products to interact with cellular proteins. Many of these viral oncoproteins share regions of sequence similarity, designated conserved region 1 and 2, which have been implicated in complex formation with pRb, th...

journal_title：Virus research

authors： Desjardins P,Pilon AA,Hassell JA,Mes-Masson AM

更新日期：1997-01-01 00:00:00

abstract：:Species members of the genus Parapoxvirus (PPV) within the family Poxviridae cause contagious pustular dermatitis in small ruminants (Orf virus, ORFV) and mostly mild localized inflammation in cattle (bovine papular stomatitis virus, BPSV and pseudocowpox virus, PCPV). All PPVs are known to be zoonotic, leading to cir...

journal_title：Virus research

authors： Friederichs S,Krebs S,Blum H,Wolf E,Lang H,von Buttlar H,Büttner M

更新日期：2014-03-06 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV) replication and transcription activator (RTA) is necessary and sufficient for the switch from KSHV latency to lytic replication. RTA activates promoters by several mechanisms. RTA can bind to sequences in viral promoters and activate transcription. In addition, RTA intera...

journal_title：Virus research

authors： Papugani A,Coleman T,Jones C,Zhang L

更新日期：2008-01-01 00:00:00

abstract：:The E2 glycoprotein of classical swine fever virus (CSFV) is involved in viral infection and induction of neutralizing antibodies. Little is known about how E2 interacts with host cells. To understand the cellular factors involved in viral replication cycle, E2 was used as bait in yeast two-hybrid screens, resulting i...

journal_title：Virus research

authors： He F,Ling L,Liao Y,Li S,Han W,Zhao B,Sun Y,Qiu HJ

更新日期：2014-01-22 00:00:00

abstract：:Previous investigations suggest that the divergence of the group I alphabaculoviruses was later than that of the group II alphabaculoviruses, however, there is no quantitative data to support this hypothesis. To examine this theory, the evolutionary rates of the 30 core genes that are conserved among all baculoviruses...

journal_title：Virus research

authors： Jiang Y,Deng F,Rayner S,Wang H,Hu Z

更新日期：2009-06-01 00:00:00

abstract：:Diagnostic methods allowing for rapid identification of pathogens are crucial for controlling and preventing dissemination after disease outbreaks as well as for use in surveillance programs. For arboviruses, detection of the presence of virus in their arthropod hosts is important for monitoring of viral activity and ...

journal_title：Virus research

authors： Mwaengo D,Lorenzo G,Iglesias J,Warigia M,Sang R,Bishop RP,Brun A

更新日期：2012-10-01 00:00:00

abstract：:The complete nucleotide sequence has been determined for the S RNA of Aino virus, a member of the Simbu serogroup (Bunyavirus genus, family Bunyaviridae). The S RNA is 850 nucleotides long (2.76 X 10(5) daltons) and in the viral complementary sequence has a short 5' non-coding region of 34 nucleotides and a more exten...

journal_title：Virus research

authors： Akashi H,Gay M,Ihara T,Bishop DH

更新日期：1984-01-01 00:00:00

abstract：:Certain insect cell lines have been shown to be permissive (TN-368) or semipermissive (IPLB-LD-652Y) for Autographa californica nuclear polyhedrosis virus (AcMNPV) replication (McClintock et al., 1986b). In this report DNA-binding proteins were identified in such cell:virus systems by hybridizing Western blots contain...

journal_title：Virus research

authors： McClintock JT,Guzo D,Guthrie KP,Dougherty EM

更新日期：1991-07-01 00:00:00

abstract：:Phylogenetic analysis has been extensively used as a tool for the reconstruction of epidemiological relations for research or for forensic purposes. It was our objective to assess the sensitivity of different phylogenetic methods and various phylogenetic programs to reconstruct epidemiological links among HIV-1 infect...

journal_title：Virus research

authors： Beloukas A,Magiorkinis E,Magiorkinis G,Zavitsanou A,Karamitros T,Hatzakis A,Paraskevis D

更新日期：2012-06-01 00:00:00

abstract：:Human rabies cases have been on the rise during the past few years in China and a total of 2651 cases were reported in 2004. To better understand the current rabies epidemics in China, we isolated rabies viruses from dogs and humans from five provinces and characterized these isolates genetically by sequencing the ent...

journal_title：Virus research

authors： Zhang YZ,Xiong CL,Zou Y,Wang DM,Jiang RJ,Xiao QY,Hao ZY,Zhang LZ,Yu YX,Fu ZF

更新日期：2006-11-01 00:00:00

abstract：:The paramyxo- and pneumoviruses are members of the order Mononegavirales, a group of viruses with non-segmented, negative strand RNA genomes. The polymerases of these viruses are multi-functional complexes, capable of transcribing subgenomic capped and polyadenylated mRNAs and replicating the genome. Although there is...

journal_title：Virus research

authors： Fearns R,Plemper RK

更新日期：2017-04-15 00:00:00

abstract：:One of the leading causes of the hand, foot and mouth disease (HFMD) is Enterovirus 71 (EV-A71), displaying symptoms such as fever and ulcers in children but some strains can produce cardiopulmonary oedema which leads to death. There is no FDA-approved vaccine for prevention of severe HFMD. The molecular determinants ...

journal_title：Virus research

authors： Yee PTI,Mohamed RAH,Ong SK,Tan KO,Poh CL

更新日期：2017-06-15 00:00:00

abstract：:Confocal microscopy revealed that Rice dwarf virus (RDV) initially accumulated in epithelial cells of the filter chamber of leafhopper vector Nephotettix cincticeps 2 days after acquisition access feeding on diseased plants. Subsequently, RDV accumulation progressed to the anterior midgut, and then spread to the nervo...

journal_title：Virus research

authors： Chen H,Chen Q,Omura T,Uehara-Ichiki T,Wei T

更新日期：2011-09-01 00:00:00

abstract：:We describe a rapid method for genetic characterisation of influenza virus genes using reverse transcription and amplification by polymerase chain reaction (RT/PCR) of all virus segments simultaneously (multiplex RT/PCR) using primers based on the conserved terminal sequences. The product has been shown to be suitable...

journal_title：Virus research

authors： Adeyefa CA,Quayle K,McCauley JW

更新日期：1994-06-01 00:00:00

abstract：:In adenovirus type 12 (Ad12)-induced tumor cells, in Ad12-transformed cells and in continuously passaged cell lines from these sources, the viral DNA is integrated in multiple copies, usually at a single chromosomal location. In different tumors or cell lines, the sites of integration of Ad12 DNA are all different. Ra...

journal_title：Virus research

authors： Pfeffer A,Schubbert R,Orend G,Hilger-Eversheim K,Doerfler W

更新日期：1999-01-01 00:00:00

abstract：:Zika virus is an emergent arbovirus that has caused a public health emergency in South America. Zika virus infection is known to cause microcephaly and other congenital defects and Guillain-Barré syndrome. Unfortunately no direct antiviral treatments are available at present. IFN-stimulated gene 15 (ISG15) is one of t...

journal_title：Virus research

authors： Wang Y,Ren K,Li S,Yang C,Chen L

更新日期：2020-10-02 00:00:00

abstract：:The Herpes simplex virus type-1 (HSV-1) regulatory protein ICP0, a RING-finger E3 ubiquitin ligase, stimulates the onset of viral lytic replication and the reactivation of quiescent viral genomes from latency. Like many ubiquitin ligases ICP0 induces its own ubiquitination, a process that can lead to its proteasome-de...

journal_title：Virus research

authors： Antrobus R,Boutell C

更新日期：2008-10-01 00:00:00

abstract：:Influenza virus rgVac1sub-P0 (H5N1) (rgVac1-P0), in which a pair of dibasic amino acid residues was introduced at the cleavage site of the HA of a reassortant of H5N2 and H7N1 viruses of duck origin, was low pathogenic in chickens. Vac1sub-P3 (H5N1) (Vac1-P3) was selected as a highly pathogenic avian influenza virus b...

journal_title：Virus research

authors： Yamamoto N,Soda K,Sakoda Y,Okamatsu M,Kida H

更新日期：2013-05-01 00:00:00

abstract：:The epitopes of six monoclonal antibodies generated against type A12 foot-and-mouth disease virus (FMDV) VP1 or its largest cyanogen bromide fragment (13 kd) were characterized. Five of these monoclonal antibodies neutralized viral infectivity. Solid-phase and competitive antigen binding assays using virion-derived an...

journal_title：Virus research

authors： Robertson BH,Morgan DO,Moore DM

更新日期：1984-09-01 00:00:00

abstract：:We selected Chinese hamster ovary (CHO) cell-adapted strains of human enterovirus 71 (HEV71) belonging to sub-genogroups B5 (HEV71-B5) and C2 (HEV71-C2) by serial passage in CHO cells at a high multiplicity of infection. During the course of CHO cell passage, virus growth improved significantly, with increasing virus ...

journal_title：Virus research

authors： Zaini Z,Phuektes P,McMinn P

更新日期：2012-05-01 00:00:00

abstract：:The nucleoprotein (N), phosphoprotein (P) and glycoprotein (G) genes of Irkut and West Caucasian bat viruses (WCBV) were sequenced and compared with those of other lyssaviruses. N gene nucleotide identities provided unequivocal separation of all lyssavirus genotypes with an identity threshold of 82%. On this basis, Ir...

journal_title：Virus research

authors： Kuzmin IV,Hughes GJ,Botvinkin AD,Orciari LA,Rupprecht CE

更新日期：2005-07-01 00:00:00

abstract：:Highly pathogenic avian H5N1 influenza A viruses occasionally infect humans and cause severe respiratory disease and fatalities. Currently, these viruses are not efficiently transmitted from person to person, although limited human-to-human transmission may have occurred. Nevertheless, further adaptation of avian H5N1...

journal_title：Virus research

authors： Imai M,Herfst S,Sorrell EM,Schrauwen EJ,Linster M,De Graaf M,Fouchier RA,Kawaoka Y

更新日期：2013-12-05 00:00:00

abstract：:In alfalfa samples analyzed by hightroughput sequencing, four de novo assembled contigs encoding gene products showing identities to alphapartitiviruses proteins were found based on BlastX analysis. The predicted amino acid (aa) sequences of two contigs presented 99-100% identity to the RNA-dependent RNA polymerase (R...

journal_title：Virus research

authors： Bejerman N,Debat H,Nome C,Cabrera-Mederos D,Trucco V,de Breuil S,Lenardon S,Giolitti F

更新日期：2019-05-01 00:00:00

abstract：:As master transcription factors for lipogenesis, sterol regulatory element-binding protein-1 (SREBP-1) has two isoforms, SREBP-1a and SREBP-1c. Hepatitis B virus X (HBx) can up-regulate the transcription of both SREBP-1a and SREBP-1c. HBx is a small protein consisting of 154 amino acids. Truncated forms of HBx, often ...

journal_title：Virus research

authors： Wu Q,Liu Q

更新日期：2015-12-02 00:00:00

abstract：:It has been previously reported that the fp25K product of Bombyx mori nucleopolyhedrovirus (BmNPV) is required for post-mortem host degradation, but the mechanism by which it regulates host degradation is still unknown. This study shows that disruption of BmNPV fp25K attenuates the expression of viral cathepsin gene (...

journal_title：Virus research

authors： Katsuma S,Nakanishi T,Shimada T

更新日期：2009-03-01 00:00:00

abstract：:Single-cell sequencing (SCS) has emerged as a valuable tool to study cellular heterogeneity in diverse fields, including virology. By studying the viral and cellular genome and/or transcriptome, the dynamics of viral infection can be investigated at single cell level. Most studies have explored the impact of cell-to-c...

journal_title：Virus research

authors： Rato S,Golumbeanu M,Telenti A,Ciuffi A

更新日期：2017-07-15 00:00:00

abstract：:Plant viruses express RNA silencing suppressor (RSS) proteins to counteract plant defence mechanisms. Here, we describe a method to assess the RSS activity based on an alfalfa mosaic virus (AMV) RNA 3 expression vector and transgenic Nicotiana tabacum plants that express the P1 and P2 subunits of the AMV replicase (P1...

journal_title：Virus research

authors： Martínez-Pérez M,Navarro JA,Pallás V,Sánchez-Navarro JA

更新日期：2019-10-15 00:00:00

abstract：:The purpose of this study was to test whether the region coding for subgroup envelope specificity was a determinant of oncogenic potential. An avian retrovirus recombinant was constructed to contain the envelope gene (env) determinant for subgroup A of an avian RNA tumor virus in one of the non-oncogenic, endogenous a...

journal_title：Virus research

authors： Wright SE,Bennett DD

更新日期：1986-11-01 00:00:00

abstract：:VP28 and VP24 are two major envelope proteins of white spot syndrome virus (WSSV). The direct interaction between VP28 and VP24 has been described in previous studies. In this study, we confirmed this interaction and mapped the interaction domains of VP28 and VP24 by constructing a series of deletion mutants. By co-im...

journal_title：Virus research

authors： Li Z,Chen W,Xu L,Li F,Yang F

更新日期：2015-03-16 00:00:00

abstract：:The CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats and CRISPR-associated protein 9) system has been widely used for viral genome editing, transcription regulation and chromosomal localization in eukaryotic cells. In this study, a guide RNA (gRNA) that specifically recognizes HSV-1 viral genomes...

journal_title：Virus research

authors： Li Z,Bi Y,Xiao H,Sun L,Ren Y,Li Y,Chen C,Cun W

更新日期：2018-01-15 00:00:00